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Isolation and characterization of canine umbilical cord blood-derived mesenchymal stem cells
Min-Soo Seo, Yun-Hyeok Jeong, Jeung-Ran Park, Sang-Bum Park, Kyoung-Hwan Rho, Hyung-Sik Kim, Kyung-Rok Yu, Seung-Hee Lee, Ji-Won 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2009, 제 10권 제 3호 2 181-187 (7 pages)
in color and had atransparent structure. The pellet formed aggregates in the bottom of the tube (Fig. 3D), and positive to toluidine blue staining (Figs. 4E and F). Discussion Isolation and characterization of stem cells derived from various tissues and sources have been one very critical issue for stem cell therapy [12,28,33]. The purpose of this study was to isolate, characterize, and... differentiation genes by RT-PCR. This finding also suggests that cMSCs might have the ability to differentiate multipotentially. It was concluded that isolated MSCs from canine cord blood have multipotential differentiation abilities. Therefore, it is suggested that cMSCs may represent a be a good model system for stem cell biology and could be useful as a therapeutic modality for canine incurable or intractable diseases, including spinal cord injuries in future regenerative medicine studies. -
The anti-tumor effect of combined treatment with arsenic trioxide and interferone-α on transplanted murine Lewis Lung carcinoma
DeugLogSeo, JeHoonYang, ChungKilWon, MyeongOkKim, JongHwanLee, SooDongKwark, PhilOkKoh 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 7 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2005, 제 45권 제 1호 3 17-23 (7 pages)
a experimental model, LL2 cells (1×10 6/mouse) were injected subcutaneously into the back region of mice. When the tumor volume reached 100 mm 3, mice were treated with 1 mg/kg arsenic trioxide, 50000 IU IFN-α, or arsenic trioxide and IFN-α. The development of tumor cells was significantly inhibited by combined treatment with arsenic trioxide and IFN-α. In arsenic trioxide and IFN-α treated... -
Therapeutic effects of orally administered CJLP55 for atopic dermatitis via the regulation of immune response
KyeongEunHyung, SooJeongKim, YeWonJang, DaKyoungLee, KeeHyeobHyun, ByoungSeokMoon, BongjoonKim, HeeyoonAhn, So-YoungPark, UyDongSohn, EonS 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.3 8 335-343 (9 pages)
of the skin barrier, a key factor in AD [16,17]. IgE level was determined to assess the degree of AD because it is observed in many other studies with a model similar to that in our study [18-20]. In this study, significant increase in serum IgE was observed in the mice with AD in the control group. Orally administered live and heat-killed CJLP55 decreased the serum IgE levels. It suggests a... inflammatory skin condition accompanied by symptoms such as edema and hemorrhage. Kimchi is a traditional fermented Korean dish consisting of various probiotics. In this study, the therapeutic effect of Lactobacillus plantarum CJLP55 isolated from Kimchi was studied in AD-induced mice. Orally administered Lactobacillus strain, CJLP55, suppressed AD symptoms and high serum IgE levels. CJLP55 administration reduced the thickness of the epidermis, infiltration of mast cells and eosinophils into the... -
p-Coumaric Acid Attenuates UVB-Induced Release of Stratifin from Keratinocytes and Indirectly Regulates Matrix Metalloproteinase 1 Release from Fibroblasts
JinKyungSeok, YongChoolBoo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.3 8 241-247 (7 pages)
retard the skin aging process. ..PAGE:7 p-Coumaric Acid Attenuates Stratifin Release by UVB 247 Because SFN derived from UVB-irradiated keratinocytes plays a role in the regulation of MMP1 expression in fibro- blasts, intervention of SFN expression or SFN-mediated signaling pathways may be useful to control expression and release of MMP1 from fibroblasts. In the present study, p-CA was tested... loss of dermal extracellular matrix is associated with skin photoaging. Recent studies demonstrated that keratinocyte-releasable stratifin (SFN) plays a critical role in skin collagen metabolism by inducing matrix metalloproteinase 1 (MMP1) expression in target fibroblasts. In the present study, we examined whether SFN released from UVB-irradiated epidermal keratinocytes increases MMP1 release from dermal fibroblasts, and whether these events are affected by p-coumaric acid (p-CA), a natural... -
Effects of Human Mesenchymal Stem Cell Transplantation Combined with Polymer on Functional Recovery Following Spinal Cord Hemisection in Rats
JiSooChoi, JoongWooLeem, KyungHeeLee, Sung-SooKim, HaeyoungSuh-Kim, SeJungJung, UnJengKim, BaeHwanLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.6 6 405-411 (7 pages)
(Model 683, Rodent Ventilator, Harvard, Holliston, MA, USA). Levels of CO 2 in expired air were maintained within the physiological range using a capnometer (Model 2200, Traverse Medical Monitors, Saline, MI, USA). Somatosensory evoked poten- tials (SSEPs) were recorded to measure the conduction re- covery of the sensory system. A special electrode (NE-120, Rhodes Medical Instruments, Inc.,... a spinal cord hemisection injury model. Rats were subjected to hemisection injuries and then divided into three groups. Two groups of rats underwent partial thoracic hemisection injury followed by implantation of either polymer only or polymer with hMSCs. Another hemisection-only group was used as a control. Behavioral, electrophysiological and immunohistochemical studies were performed on all rats. The functional recovery was significantly improved in the polymer with hMSC-transplanted group as... -
계층화된 3차원 피부색 모델을 이용한 피부색 분할
박경미, 윤가림, 김영봉, Park. Gyeong-Mi, Yoon. Ga-Rim, Kim. Young-Bong 한국정보통신학회 한국해양정보통신학회논문지 10 Pages
한국정보통신학회 한국해양정보통신학회논문지 2010, Vol.14 No.8 1809-1818 (10 pages)
요인을 포함한 영상들로부터 효율적으로 피부영역을 검출하기 위해 계층화된 피부 모델과 컨텍스트 정보를 통합하여 피부 영역 검출의 성능을 향상시키는 방법을 제안한다. 먼저, 획득된 영상들로부터 뽑아낸 피부색 색깔 값들의 확률분포를 YCbCr칼라 공간에 만들고, 그 확률 값에 따라 피부(Skin), 피부후보(Skinness), 비피부(Non-skin)의 3계층으로 분류한 3차원 피부색 모델을 만든다. 계층화된 피부색 모델을 이용하여 각 픽셀의 피부색 여부를 결정하고, 피부후보(Skinness)색에 해당하는 경우에는 이웃 화소의 정보를 고려하여... -
Comparing the osteogenic potential of canine mesenchymal stem cells derived from adipose tissues, bone marrow, umbilical cord blood, and Wharton's jelly for treating bone defects
Byung-Jae Kang, Hak-Hyun Ryu, Sung Su Park, Yoshihisa Koyama, Masanori Kikuchi, Heung-Myong Woo, Wan Hee Kim, Oh-Kyeong Kweon* 대한수의학회 Journal of Veterinary Science 12 Pages
대한수의학회 Journal of Veterinary Science 2012, 제 13권 제 3호 12 299-310 (12 pages)
spectrophotometer after color development. Measurement of VEGF M S C s w e r e s e e d e d i n 7 5 c m 2 flasks with DMEM containing 2% FBS and incubated at 37 o C in a humidified atmosphere of 5% CO2. Cultured media was collected after 48 h of incubation. Levels of VEGF in the media were then measured using an enzyme-linked immunosorbent assay kit (Quantikine Canine VEGF; R&D Systems, USA)... Alternative sources of mesenchymal stem cells (MSCs) for replacing bone marrow (BM) have been extensively investigated in the field of bone tissue engineering. The purpose of this study was to compare the osteogenic potential of canine MSCs derived from adipose tissue (AT), BM, umbilical cord blood (UCB), and Wharton's jelly (WJ) using in vitro culture techniques and in vivo orthotopic implantation assays. After canine MSCs were isolated from various tissues, the proliferation and osteogenic... -
Carbon-allotropes: synthesis methods, applications and future perspectives
P. S. Karthik, A. L. Himaja and Surya Prakash Singh 한국탄소학회 Carbon Letters 19 Pages
한국탄소학회 Carbon Letters 2014, Vol.15 No.4 1 219-237 (19 pages)
A facile microwave avenue to electrochemiluminescent two-color graphene quantum dots. Adv Funct Mater, 22, 2971 (2012). http:// dx.doi.org/10.1002/adfm.201200166. [10] Frondel C, Marvin UB. Lonsdaleite, a hexagonal polymorph of dia- mond. Nature, 214, 587 (1967). http://dx.doi.org/10.1038/214587a0. [11] Bundy FP, Kasper JS. Hexagonal diamond: a new form of carbon. J Chem Phys, 46, 3437 (1967).... The element carbon has been used as a source of energy for the past few hundred years, and now in this era of technology, carbon has played a significant and very prominent role in almost all fields of science and technology. So as an honour to this marvellous element, we humans should know about its various forms of existence. In this review article, we shed light on all possible carbon-allotropes; similarities in their synthesis techniques and the starting materials; their wide range of... -
Superhydrophobic carbon-based materials: a review of synthesis, structure, and applications
Long-Yue Meng, Soo-Jin Park 한국탄소학회 Carbon Letters 16 Pages
한국탄소학회 Carbon Letters 2014, Vol.15 No.2 5 89-104 (16 pages)
model surface II (WCA: 154~165°); Fig. 6c represents model surface III (WCA: 155~166°), where nanoscale roughness exists in the CNT array grooves. The only difference between surfaces II and III is the nanoscale roughness that exists in the CNT array grooves on surface III. These surfac- es are coated with 20 nm fuorocarbon layers that have low sur- face energy and stabilize the CNT arrays.... Materials with appropriate surface roughness and low surface energy can form superhydrophobic surfaces, displaying water contact angles greater than 150°. Superhydrophobic carbon-based materials are particularly interesting due to their exceptional physicochemical properties. This review discusses the various techniques used to produce superhydrophobic carbon-based materials such as carbon fibers, carbon nanotubes, graphene, amorphous carbons, etc. Recent advances in emerging fields such as...