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Quantification of mitral regurgitation using proximal isovelocity surface area method in dogs
Hojung Choi, Kichang Lee, Heechun Lee, Youngwon Lee, Dongwoo Chang, Kidong Eom, Hwayoung Youn, Mincheol Choi, Junghee Yoon 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2004, 제 5권 제 2호 12 163-171 (9 pages)
this anesthetic study, isoflurane anesthesia resulted in a non-significant change in echocardiographic parameters except regurgitant volume. Bach et al. [2] demonstrated general anesthesia with isoflurane altered blood pressure and LV cavity dimensions Fig. 6. Correlation between the regurgitant stroke volume (RSV) obtained by the proximal isovelocity surface area (PISA) method and by quantitative... and r = 0.996). The isoflurane anesthetic echocardiography demonstrated a significant decrease of RSV, and there was no significant change in fractional shortening (FS), ERO area, LV end-diastolic and LV end-systolic volume. ERO area showed increasing tendency after ketamine-xylazine administration, but not statistically significant. RSV, LV end-systolic and LV end-diastolic volume increased significantly (p < 0.01), whereas FS significantly decreased (p < 0.01). The PISA method is accurate and... -
A Simple Method for Predicting Hippocampal Neurodegeneration in a Mouse Model of Transient Global Forebrain Ischemia
Kyung-OkCho, Seul-KiKim, Young-JinCho, Ki-WugSung, SeongYunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.4 1 167-172 (6 pages)
o C with a heating lamp. Measurement of regional cerebral blood flow (rCBF) Cortical microperfusion was monitored using laser Doppler flowmetry (LDF; Perimed, PF5010, Jarfalla, Sweden) from anesthetic induction through 5 min after reperfusion. A flexible probe (407) was attached on the intact skull, 3.5 mm right from the bregma with cyanoacrylate adhesives. The change of cerebral blood flow... a simple method to predict the neuronal cell death in the mouse hippocampus and striatum following transient global forebrain ischemia by evaluating both cerebral blood flow and the plasticity of the posterior communicating artery (PcomA). Male C57BL/6 mice were anesthetized with halothane and subjected to bilateral occlusion of the common carotid artery (BCCAO) for 30 min. The regional cerebral blood flow (rCBF) was measured by laser Doppler flowmetry. The plasticity of PcomA was visualized by... -
Effect of Propofol, an Intravenous Anesthetic Agent, on KATP Channels of Pancreatic β-cells in Rats
EunJeePark, Dae-KyuSong, JaeKyuCheun, JungInBae, Won-KyungHo, YungEEarm 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.1 4 25-31 (7 pages)
of single channe1 records. In: Sakmann B， Neher E， eds. Single Channel Recording. London: Plenum Press 191-263， 1983 Concas A， Santoro G， Mascia MP， Maciocco E， Biggio G. The general anesthetic propofol: a biochemical tool to study the function of the GABA-coup1ed chloride channe1. Clin Neurophormacol 15: S685 -686， 1992 Friederich P， Urban BW. The inhibition of human neu rona1 K... ATP-sensitive potassium channels (KATP channels) play an important role in insulin secretion from pancreatic beta cells. We have investigated the effect of propofol on KATP channels in cultured single pancreatic beta cells of rats. Channel activity was recorded from membrane patches using the patch-clamp technique. In the inside-out configuration bath-applied propofol inhibited the KATP channel activities in a dose-dependent manner. The half-maximal inhibition dose (ED50) was 48.6⁑8.4μM... -
Comparison of the Efficacy of Caudal, Interlaminar, and Transforaminal Epidural Injections in Managing Lumbar Disc Herniation: Is One Method Superior to the Other?
Manchikanti. Laxmaiah, Singh. Vijay, Pampati. Vidyasagar, Falco. Frank J.E., Hirsch. Joshua A. 대한통증학회 The Korean journal of pain 11 Pages
대한통증학회 The Korean journal of pain 2015, Vol.28 No.1 11-21 (11 pages)
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Comparison of the effects of isoflurane versus propofolremifentanil anesthesia on oxygen delivery during thoracoscopic lung lobectomy with one-lung ventilation in dogs
Jiyoung Park, Hae-Beom Lee, Seong Mok Jeong 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 3호 12 426-433 (8 pages)
and propofol- remifentanil combined TIVA, on HPV and oxygenation during thoracoscopic lung lobectomy with 1LV in Beagle dogs. The aims of this study were (1) to evaluate the effect of each anesthetic encountered during the overall steps of thoracoscopic lung lobectomy with 1LV, and (2) to determine differences between the two anesthetic groups. Materials and Methods Experimental animals This... to open chest condition, 1LV, or surgical maneuver in either group, rather it increased during 1LV in the TIVA group. All parameters showed no significant difference between groups. Pulmonary vascular resistant index was unaffected in both groups, and there was no difference between groups except in re-ventilation phase. Accordingly, the effect of both anesthetic regimens on oxygenation was not different between groups and can be used with short-term 1LV for thoracoscopic lung lobectomy in dogs. -
Novel vertebral computed tomography indices in normal and spinal disorder dogs
Jongsu Lim, Youngmin Yoon, Taesung Hwang, Hee Chun Lee 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 2호 16 296-300 (5 pages)
needs a short anesthetic time (even light sedation can be suitable) for image acquisition. Based on these characteristics, CT could be preferred over MRI or examination of sedated patients. Therefore, clinicians should consider using CT for screening tests and for acquiring clinical indices of spinal disorders. This study was carried out to derive reference MRI and CT values for normal spine... This study was carried out to derive and evaluate reference computed tomography (CT)-based indices for normal canine spine. CT and magnetic resonance images were acquired from 12 clinically normal Beagle dogs (normal group) and 50 dogs with 56 spinal disorders (patient group). Image acquisition regions were cervical spine (C2-T1), thoracic spine (T1-T13), and lumbar spine (L1-L7). Measured indices were: the ratios of width to height of the spinal cord including the dura matter (CR) and of the... -
Evaluation of the ureteral jet in dogs by using color Doppler ultrasonography
Hyunjung Oh, Seongsoo Kim, Suyeon Kim, Jeosoon Lee, Sookyung Yun, Junghee Yoon, Joohyun Jung, Mincheol Choi 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 3호 17 399-406 (8 pages)
jet. The urinary bladder was scanned in dorsal recumbency to assess the degree of distention. Real-time examination was performed in each dog when the urinary bladder was partially distended. Anesthetic (Zoletil 50; Virbac, France) was injected intravenously at a dose of 5 mg/kg, and an equal amount of the anesthetic was injected into the antebrachial muscle region. Under anesthesia, the... Ureteral jets are the result of a forceful ejection of urine from the vesicoureteral junction into the urinary bladder. By using color Doppler ultrasonography (US), we aimed to identify distinct ureteral jets in dogs, provide insight into ureteral obstruction, and facilitate study of urodynamics and vesicoureteric sphincter function via pulsed Doppler US. Color Doppler US was applied to detect urinary flow from the right ureteral orifices in eight healthy beagles. Under anesthesia, 0.9% saline... -
Gintonin, an exogenous ginseng-derived LPA receptor ligand, promotes corneal wound healing
Hyeon-Joong Kim, Joon Young Kim, Byung-Hwan Lee, Sun-Hye Choi, Hyewon Rhim, Hyoung-Chun Kim, Seoung-Yob Ahn, Soon-Wuk Jeong, Min 대한수의학회 Journal of Veterinary Science 11 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 3호 16 387-397 (11 pages)
applying the fluorescein staining test after using local anesthetic eye drops (Alcaine; Alcon). After staining the cornea with fluorescein, the ocular surface was photographed by using 8× slit-lamp biomicroscopy under cobalt blue light. In the obtained images, the Image-Pro Plus program (ver. 4.5.0.29; Media Cybernetics, USA) was used to measure the area of fluorescein uptake in the cornea.... Ginseng gintonin is an exogenous ligand of lysophosphatidic acid (LPA) receptors. Accumulating evidence shows LPA helps in rapid recovery of corneal damage. The aim of this study was to evaluate the therapeutic efficacy of gintonin in a rabbit model of corneal damage. We investigated the signal transduction pathway of gintonin in human corneal epithelium (HCE) cells to elucidate the underlying molecular mechanism. We next evaluated the therapeutic effects of gintonin, using a rabbit model of... -
Effect of canine mesenchymal stromal cells overexpressing heme oxygenase-1 in spinal cord injury
Seung Hoon Lee, Yongsun Kim, Daeun Rhew, Ahyoung Kim, Kwang Rae Jo, Yongseok Yoon, Kyeung Uk Choi, Taeseong Jung, Wan Hee Kim, O 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 3호 15 377-386 (10 pages)
Korea). Anesthesia was maintained with 2% isoflurane inhalation (Aerrane; Ilsung Pharmaceuticals, Korea) in oxygen. The anesthetic monitor Datex-Ohmeda (Microvitec Display, UK) was used to monitor physiological parameters, including rectal temperature, oxygen saturation, end tidal CO 2, and pulse rate, during anesthesia. Hemilaminectomy was performed at the fourth lumbar segment (L4). A... Heme oxygenase-1 (HO-1) is a stress-responsive enzyme that modulates the immune response and oxidative stress associated with spinal cord injury (SCI). This study aimed to investigate neuronal regeneration via transplantation of mesenchymal stromal cells (MSCs) overexpressing HO-1. Canine MSCs overexpressing HO-1 were generated by using a lentivirus packaging protocol. Eight beagle dogs with experimentally-induced SCI were divided into GFP-labeled MSC (MSC-GFP) and HO-1-overexpressing MSC... -
Optimal scan delay depending on contrast material injection duration in abdominal multi-phase computed tomography of pancreas and liver in normal Beagle dogs
Soo-Young Choi, In Lee, Ji-Won Seo, Hyun-Young Park, Ho-Jung Choi, Young-Won Lee 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 4호 15 555-561 (7 pages)
counts, serum chemistry analyses, and radiography of the thorax and abdomen. Upon echocardiography, left ventricular ejection fraction by Simpson’s method and mitral valve inflow by pulsed-wave Doppler examination were measured to identify the normal cardiac function in all dogs. Preparations for experimental CT scan The dogs were not fed for 6 hours before the anesthetic procedure, and a... of two experiments employing the crossover method. In experiment 1, three dynamic scans at the porta hepatis were performed using 5, 10 and 15 sec injection durations. In experiment 2, two CT scans consisting of five multi-phase series with different scan delays of 5 sec intervals for bolus-tracking were performed using 5, 10 and 15 sec injection duration. Mean arrival times to aortic enhancement peak (12.0, 15.6, and 18.6 sec for 5, 10, and 15 sec, respectively) and pancreatic parenchymal peak...