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Up-regulation of CD11c Expression on Human Acute Myelogenous Leukemia Cells by Flt-3 Ligand
서기, 곽종영, Xu. Qi, Kwak. Jong-Young 한국생명과학회 생명과학회지 8 Pages
한국생명과학회 생명과학회지 2009, Vol.19 No.12 1690-1697 (8 pages)
HL-60 세포와 NB4 세포의 CD11c 발현도 증가시켰으나 THP-1 세포에서는 아무런 영향이 없었다. CD11c의 발현과 비교하여 CD11b의 발현은 Flt-3 리간드에 의하여 KG-1 세포에서는 약하게 증가하였으나 NB4 세포와 HL-60 세포에서는 증가되지 않았다. KG-1 세포를 Flt-3 리간드로 처리하였을 때 extracellular signal-regulated kinase-1/2 (ERK-1/2)와 p38-mitogen-activated protein kinase (p38-MAPK)의 단백질 인산화가 증가되었으며 Flt-3 리간드에 의한 CD11c 발현의 증가는 MEK의 억제제인PD98059에 의하여 사라짐을 확인하였다. 본... -
생쥐 수지상세포에서 발현하는 CD11c 프로모터의 규명
김봉긔, 김정식, 박정규, Kim. Bon-Gi, Kim. Jung-Sik, Park. Chung-Gyu 대한면역학회 Immune network : official journal of the Korean association of immunobiologists 6 Pages
대한면역학회 Immune network : official journal of the Korean association of immunobiologists 2008, Vol.8 No.4 137-142 (6 pages)
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Effectiveness of Brucellosis Eradication Program in the Republic of Korea during Decline Period
Hac hung Yoon, Oun Kyong Moon, Moon Her, Woo seog Jeong, Jida Choi, Yong Myong Kang, Hyo Young Ahn, Yong Sang Kim 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 춘계학술심포지움 83 181-181 (1 pages)
with antigen presentation, MHC II, CD40, CD80, and CD86. In addition, the lineage markers expressed on myeloid DC, CD11b, CD11c, and CD172a, were also highly expressed on th ese cells, indicating this subsetcontains myeloid DC. Conclusions: A mAb to bovine CD209 (209MD26A) was successfully developed in the current study. The mAb detects a population in PBMC corresponding to human CD209 +... -
Characterization of Blood Circulating CD209 (DC-SIGN) Expressing Cells in Bovine using Flow Cytometry
Kun Taek Park, Yong Ho Park, William Davis 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 춘계학술심포지움 82 181-181 (1 pages)
with antigen presentation, MHC II, CD40, CD80, and CD86. In addition, the lineage markers expressed on myeloid DC, CD11b, CD11c, and CD172a, were also highly expressed on th ese cells, indicating this subsetcontains myeloid DC. Conclusions: A mAb to bovine CD209 (209MD26A) was successfully developed in the current study. The mAb detects a population in PBMC corresponding to human CD209 +... -
Prevalence, Antibiotic Resistance, and Virulence Features of Shiga Toxin-producing Escherichia coli Isolates from the Retail Meats and Meat by-products in Korea
June Bong Lee, Dalmuri Han, Jeong Hoon Park, Hyung Tae Lee, Hyun Seok Joh, Yeon Soo Chung, Suk Shin, Yong Ho Park , Chong Hae Hong, Jang 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 춘계학술심포지움 81 180-181 (2 pages)
with antigen presentation, MHC II, CD40, CD80, and CD86. In addition, the lineage markers expressed on myeloid DC, CD11b, CD11c, and CD172a, were also highly expressed on th ese cells, indicating this subsetcontains myeloid DC. Conclusions: A mAb to bovine CD209 (209MD26A) was successfully developed in the current study. The mAb detects a population in PBMC corresponding to human CD209 +... -
Lymphosarcoma in the spinal cord of a cat
Jae Hyeon Shin, Yong Eun Shin, Jae Hoon Kim 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 286 365-366 (2 pages)
of dendritic cell differentiation including CDla, CD1c, and CD11c [2]. By contrast to the high prevalence of histiocytoma in the dog, cutaneous histiocytoma is very rarely recognized in the cat and the tumor does not feature in the majority of published surveys of feline cutaneous neoplasia [1]. In the study, we describe the histopathologic characteristics of cutaneous histiocytoma in a cat.... -
Cutaneous histiocytoma in a cat
Hyeon Ho Song, Ja Sil Park, Jae Hoon Kim 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 285 365-365 (1 pages)
of dendritic cell differentiation including CDla, CD1c, and CD11c [2]. By contrast to the high prevalence of histiocytoma in the dog, cutaneous histiocytoma is very rarely recognized in the cat and the tumor does not feature in the majority of published surveys of feline cutaneous neoplasia [1]. In the study, we describe the histopathologic characteristics of cutaneous histiocytoma in a cat.... -
A Salmonella Typhi ghost induced by the E gene of phage X174 stimulates dendritic cells and efficiently activates the adaptive immune response
Gayeon Won, Seong Kug Eo, Sang-Youel Park, Jin Hur, John Hwa Lee 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 4호 9 536-542 (7 pages)
CD11c + cell populations using fluorescence-activated cell sorting (FACS). (A) Representative FACS histogram of the surface marker-positive cell population. (B) Percentages of co-stimulatory molecule-positive DCs. NS, non-stimulated; LPS, lipopolysaccharide. *p 0.05 (vs. non-stimulated DCs). measured in purified DCs pulsed with STG, LPS, or culture medium alone. The proportion of CD11c +CD80 +... Previously, we genetically engineered a Salmonella Typhi bacterial ghost (STG) as a novel inactivated vaccine candidate against typhoid fever. The underlying mechanism employed by the ghost in stimulating the adaptive immune response remains to be investigated. In this study, we aimed to evaluate the immunostimulatory effect of STG on mouse bone marrow-derived dendritic cells (BMDCs) and its activation of the adaptive immune response in vitro. Immature BMDCs were stimulated with STG, which... -
Immunogenicity of recombinant Lactobacillus plantarum NC8 expressing goose parvovirus VP2 gene in BALB/c mice
Yu-Ying Liu, Wen-Tao Yang, Shao-Hua Shi, Ya-Jie Li, Liang Zhao, Chun-Wei Shi, Fang-Yu Zhou, Yan-Long Jiang, Jing-Tao Hu, Wei Gu, 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 2호 5 159-167 (9 pages)
cells from spleen) from mice administered pSIP409-VP2/NC8 (thick red line) in comparison with the mice administered pSIP409/NC8 (thick green line) or PBS (filled histograms with gray color). (B) The CD11c + levels of Group A were significantly different from those of Group B (*p 0.05). (C) Gate strategy. (D) There were significantly different percentages of CD3 + CD4 + and CD3 + CD8 + cells betwe... L. plantarum strain, and the ratios and numbers of CD11c, CD3CD4, CD3CD8, and interferon gamma- and tumor necrosis factor alpha-expressing spleen lymphocytes in the pSIP409-VP2/NC8 group were higher than those in the control groups. In addition, we assessed the capacity of L. plantarum SIP409-VP2/NC8 to induce secretory IgA production. We conclude that administered pSIP409-VP2/NC8 leads to relatively extensive cellular responses. This study provides information on GPV infection and offers a... -
Mycobacterium vaccae induces a strong Th1 response that subsequently declines in C57BL/6 mice
Lijiao Zhang, Yanlong Jiang, Ziyin Cui, Wentao Yang, Limin Yue, Yingcong Ma, Shaohua Shi, Chunfang Wang, Chunfeng Wang, Aidong Q 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 4호 9 505-513 (9 pages)
IgG), CD25 (3C7, rat IgM), CD152 (cytotoxic T-lymphocyte-associated protein [CTLA]-4, cloneUC10-4F10-11, hamster anti-mouse IgG), CD11b (Mac-1, clone M1/70, rat anti-mouse IgG), CD11c (clone N418, anti-mouse IgG), CD45R/B220 (RA3-6B2, rat anti-mouse IgG), and Ly-6C/Gr1 (AL-21, rat anti-mouse IgG) (BD Biosciences). The monoclonal antibody data acquisition and analysis were performed by BD... Mycobacterium (M.) vaccae is a fast-growing species of saprophytic bacteria that is widely distributed. To understand the host immune responses induced by M. vaccae isolated from bovine submaxillary lymph nodes, C57BL/6 mice were infected with reference strain M. bovis Bacillus Calmette-Gu?rin (BCG) and isolated M. vaccae using intraperitoneal injections. Comparison of the bacterial replication and organ pathology between M. vaccae and M. bovis BCG revealed that M. vaccae was more malignant than...