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Pathological features of bone marrow transplantation-related toxicity in a mouse
Yong-Hoon Kim, Chang-Su Ha, Hyun-Sook Lee, Sun-Hwa Lim, Kyoung-Sik Moon, Moon-Koo Chung, Hwa-Young Son* 대한수의학회 Journal of Veterinary Science 3 Pages
대한수의학회 Journal of Veterinary Science 2009, 제 10권 제 4호 15 361-363 (3 pages)
thymus, skin, liver, gastrointestinal tract, gonads, and heart are targeted in autoimmune-like complication [1,4,5,16]. However, reports dealing with the pathological features of BMT related- toxicity are limited. In the present study, we report the histopathological features, hematological values, and BM cytology of a mouse transplanted with mock-transduced bone marrow, which was found... In this case report, we present a mock-transduced bone marrow (BM) transplantation in a mouse, which was found moribund and autopsied to evaluate pathogenesis. Macroscopically, red discoloration of systemic organs was observed. Hematological values revealed a decrease in white blood cells, red blood cells, hematocrit, hemoglobin, and platelets, but an increase in reticulocytes. In BM cytology, hematopoietic cell lines were severely depleted. Histopathologically, hemorrhage in the cerebellar... -
Protective and therapeutic effects of an extract mixture of alder tree, labiate herb, milk thistle green bean-rice bran fermentation, and turnip against ethanol-induced toxicity in the rat
Min-Won Baek, Seung-Hyeok Seok, Hui-Young Lee, Dong Jae Kim, Byoung-Hee Lee, Young-Tae Ahn, Kwang-Sei Lim, Chul-Sung Huh, Jae-Ha 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 1호 5 31-37 (7 pages)
Science, College of Veterinary Medicine Seoul National University and Korea Research Foundation Grant (KRF-005-F00077). References 1. Baek MW, Seok SH, Lee HY, Kim DJ, Lee BH, Ahn YT, Lim KS, Huh CS, Park JH. Protective Effect of Y-mix in an Ethanol-induced Toxicity Model. Lab Anim Res 2005, 21, 413-417. 2. Bailey SM, Cunningham CC. Acute and chronic ethanol in- creases reactive oxygen speci... drugs were used for treatment for two weeks prior to administering a single oral dose of ethanol (3 g/kg body weight). The herbal extract mixture and yogurt added to the herbal extract mixture were found to provide protection against ethanolinduced toxicity comparable to the commercial drug treatment, according to the serum and histopathological analysis. It was also shown that co-treatment with herbal extract mixture and yogurt against a triple oral dose of ethanol (2 g/kg body weight, over one... -
A Review on Renal Toxicity Profile of Common Abusive Drugs
VarunParkashSingh, NirmalSingh, AmteshwarSinghJaggi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.4 13 347-357 (11 pages)
of renal toxicity. The renal complications include a wide range of glomerular, interstitial and vascular diseases leading to acute or chronic renal failure. The present review discusses the renal toxicity profile and possible mechanisms of commonly abused drugs including morphine, heroin, cocaine, nicotine, caffeine and alcohol. Key Words: Caffeine, Cocaine, Heroin, Morphine, Renal failure... are excreted through the kidneys and, thus, the renal complications of these drugs are very common. Morphine, heroin, cocaine, nicotine and alcohol are the most commonly abused drugs, and their use is associated with various types of renal toxicity. The renal complications include a wide range of glomerular, interstitial and vascular diseases leading to acute or chronic renal failure. The present review discusses the renal toxicity profile and possible mechanisms of commonly abused drugs... -
Suppression of the growth of human choriocarcinoma cellsby therapeutic neural stem cells expressing cytosine deaminase and interferon- β in cellularand xenografte mouse models
Goen Tae Park, Kyung Chul Choi 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 300 498-498 (1 pages)
will further examine the invivo toxicity of CS in a xenografted mouse model transplanted with JEC-3placenta cancer cells. References [1] Bainbridge SA, Sidle EH, Smith GN. Direct placental effects of cigarette smoke protect women from pre-eclampsia: the specific roles of carbon monoxide and antioxidant systems in the placenta. Med Hypotheses 64: 17 [2] Lambers DS, Clark KE. The maternal and... -
Exposure of cigarette smoke extract repressed cellviability of placental cells via regulation of cell cycle related genes in a placentacell model
Hae Miru Lee, Kyung Chul Choi 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 299 497-498 (2 pages)
will further examine the invivo toxicity of CS in a xenografted mouse model transplanted with JEC-3placenta cancer cells. References [1] Bainbridge SA, Sidle EH, Smith GN. Direct placental effects of cigarette smoke protect women from pre-eclampsia: the specific roles of carbon monoxide and antioxidant systems in the placenta. Med Hypotheses 64: 17 [2] Lambers DS, Clark KE. The maternal and... -
Retrospective study in cattle abortions submitted to the QIA, 2002~2015
Si Yeon Yang, Eun Jin Choi, Kyung Hyun Lee, Hyun Kyoung Lee, Yeon Hee Kim, Ha Young Kim, Byung Jae So 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 355 385-386 (2 pages)
in vivo toxicity of CS in a xenografted mouse model transplanted with JEC-3 and BeWo placenta cancer cells. Conclusions: The present results that CS components such as BaP and AN may induce apoptosis of JEG-3 and BeWo human choriocarcinoma cancer cells by increasing ROS level and simultaneously activating ER-stress. References: [1] Lee HM, Kim CW, Choi DW, Choi KC 2016 Three components of... -
Treatment with cigarette smoke components altered the cell proliferation, apoptosis in human choriocarcinoma cancer cell lines via ROS-induced ER-stress pathway
Soo Min Kim, Hae Miru Lee, Kyung Chul Choi 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 354 385-385 (1 pages)
in vivo toxicity of CS in a xenografted mouse model transplanted with JEC-3 and BeWo placenta cancer cells. Conclusions: The present results that CS components such as BaP and AN may induce apoptosis of JEG-3 and BeWo human choriocarcinoma cancer cells by increasing ROS level and simultaneously activating ER-stress. References: [1] Lee HM, Kim CW, Choi DW, Choi KC 2016 Three components of... -
Cigarettesmoke impaired maturation of ovarian follicle and abnormal growth of uterus innerwall via changed expression of estrogen receptors and cell cycle arrest proteinp21 in female rats
Hae Miru Lee, Cho Won Kim, Kyung Chul Choi 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 353 384-385 (2 pages)
in vivo toxicity of CS in a xenografted mouse model transplanted with JEC-3 and BeWo placenta cancer cells. Conclusions: The present results that CS components such as BaP and AN may induce apoptosis of JEG-3 and BeWo human choriocarcinoma cancer cells by increasing ROS level and simultaneously activating ER-stress. References: [1] Lee HM, Kim CW, Choi DW, Choi KC 2016 Three components of... -
Melatonin attenuates ariway inflammation induced by cigarette smoke via enhancement of SIRT 1 expression
Na Rae Shin, Je Won Ko, Sung Hyeuk Park, Jong Choon Kim, In Sik Shin 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 190 314-315 (2 pages)
has increased inrecent years. Copper oxide nanoparticles (CuONPs) are one of the most commontypes of nanoparticles, and they are mainly used as catalysts and preservatives. However, limited toxicity data areavailable on the toxicity of CuONPs to the respiratory system Materials and Methods: We investigated the effect of CuONPs on fibroticresponses in the respiratory tract using a mouse and...