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- 대한생리학회지(6)
- THE KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY(4)
- 대한기계학회론문집. TRANSACTIONS OF THE KOREAN SOCIETY OF MECHANICAL ENGINEERS. A. A(2)
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- 전기전자재료학회지= THE JOURNAL OF THE KOREAN INSTITUTE OF ELECTRICAL AND ELECTRONIC MATERIAL ENGINEERS(2)
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Alterations of Amino Acid Level in Depressed Rat Brain
PeiYang*, XuechunLi*, JianNi, JingchenTian, FuJing, ChanghaiQu, LongfeiLin, HuiZhang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.5 3 371-376 (6 pages)
LC-MS/MS 3200 (AB SCIEX, USA). The LC system was on-line couplet to an Agilent 6460 Triple Quad LC/MS equipped with the electro- spray ionization (ESI) source. Curtain Gas was set at 20 Psi and Collision Gas was performed in medium mode. 5500 V was chosen for IonSprayVoltag. The Ion Source Gas1 and Gas2 were set at 55 Psi and 60 Psi respectively. Temper- ature was set at the high level of 580... Amino-acid neurotransmitter system dysfunction plays a major role in the pathophysiology of depression. Several studies have demonstrated the potential of amino acids as a source of neuro-specific biomarkers could be used in future diagnosis of depression. Only partial amino acids such as glycine and asparagine were determined from certain parts of rats’ brain included hippocampi and cerebral cortex in previous studies. However, according to systematic biology, amino acids in different area of... -
Effects of Somatostatin on the Responses of Rostrally Projecting Spinal Dorsal Horn Neurons to Noxious Stimuli in Cats
SungJunJung, Su-HyunJo, SanghyuckLee, EunhuiOh, Min-SeokKim, WooDongNam, SeogBaeOh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.5 6 253-258 (6 pages)
Hz) stimulation, and 3) collision. Arrow (↑) represents the elect- rical stimuli to sciatic nerve. The activity of RPSDH neuron () b y electrical stimuli was observed after a constant latency. Gray circle () means the activity of RPSDH neuron, which vanished after collision (▼) by cervical dorsal column stimulation. In this experi- ment, RPSDH neurons were used. (B) Iontophoretic application o... Somatostatin (SOM) is a widely distributed peptide in the central nervous system and exerts a variety of hormonal and neural actions. Although SOM is assumed to play an important role in spinal nociceptive processing, its exact function remains unclear. In fact, earlier pharmacological studies have provided results that support either a facilitatory or inhibitory role for SOM in nociception. In the current study, the effects of SOM were investigated using anesthetized cats. Specifically, the... -
The Role of Somatostatin in Nociceptive Processing of the Spinal Cord in Anesthetized Cats
SungJunJung, JooMinPark, JunHoLee, JihyeLee, SangJeongKim, JunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.4 1 365-373 (9 pages)
recorded cell is projecting based on (1) response of a constant latency (100 μA and 1 Hz)， (2) ability of the spike to follow high-frequency stimulus trains (333 Hz， 3 pulses)， and (3) collision between the antidromic spike and the orthodromic action potentials evoked by natural stimulation to the RF (Trevino et al， 1973). Experimental procedure When a single neuronal activity of... Somatostatin (SOM) is one of the major neuropeptides in dorsal root ganglion cells, but its role in spinal nociceptive process has not been well known. In present study we aimed to investigate the effect of SOM on the response of dorsal horn neurons to the various types of peripheral nociceptive stimuli in anesthetized cats. Using carbon-filament microelectrode, the single cell activities of wide dynamic range neurons were recorded from the lumbosacral enlargement after noxious mechanical... -
Sensory Inputs to Upper Cervical Spinal Neurons Projecting to Midbrain in Cats
JongHoKim, Han-SeongJeong, Jong-SeongPark, Jong-KeunKim, Sah-HoonPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.1 2 9-19 (11 pages)
for the identification of antidromically activated SMT neuron. A: antidromic responses of C) SMT neuron. Discrete threshold and constant latεncy of antidromic spike to midbrain stimulation (a)， collision with spontaneous or evoked orthodromic impulse (b)， and ability to follow a high frequency (333 Hz) stimuli without any modification in latency (c) were considered as criteria. The laten... -
Discharge Patterns and Peripheral Nerve Inputs to Cardiovascular Neurons in the Medulla of Cats: Comparison between the lateral and medial medulla
Kim, Sang-Jeong, Lim, Won-Il, Park, Myoung-Kyu, Lee, Jin, Kim, Jun 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1994, 제 28권 제 2호 3 133-142 (10 pages)
by the collision test: problems of interpretation. Brain Res 112, 283-298 Gebber GL & Barman SM (1980) Basis for 2-6 cycle/s rhythm in sympathetic nerve discharge. Am J Physiol 239, R48-R56 Goldman PL, Collins WF, Taub A & fitzmartin J (I 972) Evoked bulbar reticular unit activity following delta fiber stimulation of peripheral somatosensory nerve in cat. Exp... The discharge patterns and peripheral nerve inputs to cardiovascular neurons were investigated in rostral ventrolateral medulla (RVLM) and raphe nucleus of cats. The data from the two were compared to determine their roles in cardiovascular regulation and the endogenous analgesic system. Animals were anesthetized with α-chloralose and single cell activities were recorded by carbon-filament microelectrode and their relationships with cardiovascular activity were analyzed. In RVLM area, a total... -
Functional Characteristics of Lumbar Spinal Neurons Projecting to Midbrain Area in Rats
Park, Sah-Hoon, Kim, Geon 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1994, 제 28권 제 2호 1 113-122 (10 pages)
3)collision with spontaneous or evoked orthodromic impulses, and 4)discrete threshold (Fig. I). Spinal single cell units acti- vated by antidromic stimulation were recorded at the spinal cord level of L2-L5 through carbon filament electrodes (tip resistance, 1-4 MQ). It was necessary to make small holes in the pia to allow smooth penetration by the glass mi-... gray and midbrain reticular formation. Recording sites were located in laminae I-VII of spinal cord segments of L2-L5. Receptive field properties and responses to calibrated mechanical stimulation were studied in 78 SMT cells. Mean conduction velocity of SMT neurons was 19.1±1.04 m/sec. SMT units were classified according to their response profiles into four groups: wide dynamic range (58%), deep/tap (23%), high threshold (9%) and low threshold (3%). A simple excitatory receptive field was... -
Cardiovascular Neurons Mediating Somatosympathetic Reflex in Rostral Ventrolateral Medulla
Goo, Yong-Sook, Kim, Sang-Jeong, Kim, Jun, Sung, Ho-Kyung 대한생리학회 대한생리학회지 14 Pages
대한생리학회 대한생리학회지 1993, 제 27권 제 2호 7 185-198 (14 pages)
A300, WPI) coupled with an isolator (A360, WPI). The reticulospi- nal neurons were identified based on three basic criteria: 1) constant onset latency, 2) high frequency following, and 3) collision with spon- taneous activity (Morrison & Gebber, 1984). Peripheral nerve: The sciatic nerve was dis- sected and hooked with a tripolar platinum electrode for electrical stimulation to elicit the... The rostral ventrolateral medulla (RVLM) includes vasopressor neurons, which transmit activation signals to the intermediolateral nucleus (IML) of the spinal cord, where the preganglionic sympathetic nucleus is located, to raise arterial blood pressure (BP). However, controversy exists as to the possible depressor area in the RVLM and the pathway involved. The present study persued evidence far the location of depressor neurons and the pathway by simultaneously observing changes in BP and the... -
Electrophysiological Study on Medullospinal Tract Cells Related to Somatosympathetic Reflex in the Cat
Kim, Sang-Jeong, Goo, Yong-Sook, Kim, Jun 대한생리학회 대한생리학회지 14 Pages
대한생리학회 대한생리학회지 1992, 제 26권 제 1호 8 75-88 (14 pages)
pulse. Also, the spontaneous activity of this cell collided with the activity evoked by electrical stimulation. In this case, the conduc- tion distance was 10 cm and the calculated con- duction velocity was 5.07 m/sec, in the range of B-nerve fibers. A considerable number of cells showed no spontaneous activity, so the collision was confirmed with the cell activity ac- tivated by peripheral... not. Between these two groups, rostro-caudal coordinate of the distribution from obex [4.7±0.2 (mean S.E.) mm, 4.1 0.1 mm], depth from dorsal surface (5.5±0.2mm, 4.9±0.1mm and conduction velocity (9.9±1.7m/sec, 16.7±1.9 m/sec) were significantly different (p<0.05). In spontaneously discharging group, characteristics of rostral and caudal groups were significantly different and we demonstrated that cells in rostral group mediate somatosympathetic reflex. From these results, we conclude that... -
The Electrophysiological Characteristics of Medullospinal Tract Cells in Cat Ventrolateral Medulla
Lee, Woo-Yong, Kim, Sang-Jung, Kim, Jun 대한생리학회 대한생리학회지 11 Pages
대한생리학회 대한생리학회지 1991, 제 25권 제 2호 11 211-221 (11 pages)
of seventy cells in medulla had constant latency and responded to high frequency stimula- tion to thoracic cord. Among them fifty-six cells were identified as medullospinal tract cells either by collision with spontaneous activities or activities evoked by sciatic nerve stimulation(27 /56), or by determining the refractory period (29/56). Thirty-one of these cells branched to the contralateral... collision with spontaneous activities or activities evoked by sciatic nerve stimulation(27/56), or by determining the refractory period (29/56). Thirty-one of these cells branched to the contralateral thoracic spinal cord, twenty-one cells to the ipsilateral side and remaining four cells branched to both sides. The conduction velocity of cells branching to the contralateral side was 29±2.9 m/sec and that of cells to the ipsilateral side was 39.1±6.0 m/sec. When medulla was devided into two by...