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총 89건 검색
본문검색 결과만 보기
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Differential Functional Expression of Clotrimazole-sensitive Ca2+-activated K+ Current in Bal-17 and WEHI-231 Murine B Lymphocytes
HaifengZheng, JaeHongKo, JooHyunNam, YungEEarm, SungJoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.1 4 19-24 (6 pages)
resting membrane potential described in this study was measured under the zero- current clamp condition of the whole-cell patch clamp. Vol- tage and current data were low pass filtered (5 kHz), stored in a Pentium-grade computer and analyzed using pCLAMP software version 9.0 and Origin version 6.1 (Microcal Soft- ware Inc., Northampton, MA). Data were represented as mean± S.E.M.. Student's t... pipette solution revealed a voltage-independent K current that was blocked by clotrimazole (1 mM), an SK4 blocker. The expression of mRNAs for SK4 was confirmed in both Bal-17 and WEHI-231 cells. The density of clotrimazole-sensitive SK4 current was significantly larger in Bal-17 than WEHI-231 cells (11.4⁑3.1 Vs. 5.7⁑1.15 pA/pF). Also, the chronic stimulation of B cell receptors (BCR) by BCR-ligation (anti-IgM Ab, 3μg/ml, 8∼12 h) significantly upregulated the... -
The Current Concept on Mechanism of Positive Inotropic Action of Cardiac Glycosides on the Heart
Lee Kwang-Soo 대한약리학회 대한약리학잡지 23 Pages
대한약리학회 대한약리학잡지 1986, 제 22권 제 1호 1 1-23 (23 pages)
to zero ex- ternal Na concentration. J Mo! Cell Cardiol 16: 155-164, 1.984 Beeler GW Jr : Ionic currents in cardiac muscle: a framework for glycoside action. Fed Proc 36: 2209-2213, 1977 - 1 4 - ..PAGE:15 Beeler GW and Reuter H: Membrane calcium current in ventricular myocardial fibers. J Physiol (London) 207: 191-209, 1970a Beeler GW and Reuter H: The relation between membrane... -
Reliability and validity of the patellofemoral disability index as a measure of functional performance and subjective pain in subjects with patellofemoral pain syndrome
Mastour Saeed Alshaharani, Everett Bernell Lohman, Khaled Bahjri, Travis Harp, Mansoor Alameri, Noha S. Daher 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2018, 제 7권 제 2호 3 61-66 (6 pages)
any of the following conditions were excluded from the study: traumatic injuries to the knee join/lower limbs, me- niscus lesion or ligamentous-related pathology, neuro- logical disorders, past and current medical history of dia- betes, osteoarthritis, osteoporosis or rheumatoid arthritis, and/or use of over-the-counter pain medication during the study period. Subjects were not screened for low... stairs. The Patellofemoral Disability Index (PDI) was developed to assess the effect of pain on functional activities in individuals with PFPS. The objectives of the current study were to determine the internal consistency, test-retest reliability, and validity of this index. Design: Cross-sectional study. Methods: Forty-one subjects who had PFPS with a mean age of 28.8±5.0 years and a mean body mass index of 25.6±4.7 kg/m2 participated in the study. All subjects were concurrently enrolled in... -
Long-Term Surveillance of Classical Swine Fever in Wild Boar (Sus scrofa sp.) in South Korea from 2010-2016
Sung Hyun Choi, Son Il Pak, Dong Jun An 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 81 227-228 (2 pages)
y populations. The goal of the current study was to describe the spatial pattern of AI risk using the data from the routine AI surveillance during the period 2014-2015. Materials and Methods: The number of domestic poultry farms including broiler, egg-layer, or breed chicken and duck and the number of AI-positive cases were obtained from the Animal and Plant Quarantine Agency. Data were... -
Spatial Pattern of Avian Influenza Risk Using Surveillance Data in the Republic of Korea, 2014-2015
Eu Tteum Kim, Son Il Pak, Woo-seog Jeong, Hong Shik Park 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 80 227-227 (1 pages)
y populations. The goal of the current study was to describe the spatial pattern of AI risk using the data from the routine AI surveillance during the period 2014-2015. Materials and Methods: The number of domestic poultry farms including broiler, egg-layer, or breed chicken and duck and the number of AI-positive cases were obtained from the Animal and Plant Quarantine Agency. Data were... -
Mapping the Global Movement Patterns of Migratory Birds with Special Reference to Potential Risk of HPAI Transmission
Son Il Pak, Weon Hwa Jheong, Han Soo Lee 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 67 240-241 (2 pages)
to target interven tions and evaluate current preventive programs. Materials and Methods: Information about the HPAI cases since 2003were provided from the Quarantine Inspection Agency, the Ministry of Agricult ure, Food and Rural Affairs, using individual farm-basis which denotes essential information on geographic area, number of animals, date of notification for suspected cases, date of... -
Geospatial Analysis and Mapping the Risk of Highly Pathogenic Avian Influenza of Poultry Farms in Korea (2003-2017)
Eu Tteum Kim, Son Il Pak 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 66 240-240 (1 pages)
to target interven tions and evaluate current preventive programs. Materials and Methods: Information about the HPAI cases since 2003were provided from the Quarantine Inspection Agency, the Ministry of Agricult ure, Food and Rural Affairs, using individual farm-basis which denotes essential information on geographic area, number of animals, date of notification for suspected cases, date of... -
Investigating the Spatial Distribution of Highly Pathogenic Avian Influenza in Wild Birds in Korea(2004-2017)
Eu Tteum Kim, Son Il Pak 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 65 239-240 (2 pages)
to target interven tions and evaluate current preventive programs. Materials and Methods: Information about the HPAI cases since 2003were provided from the Quarantine Inspection Agency, the Ministry of Agricult ure, Food and Rural Affairs, using individual farm-basis which denotes essential information on geographic area, number of animals, date of notification for suspected cases, date of... -
Toward the development of a one-dose classical swine fever subunit vaccine
Rachel F. Madera, Lihua Wang, Wenjie Gong, Yulia Burakova, Sterling Buist, Jerome Nietfeld, Jamie Henningson, Ada G. Cino-Ozuna, Changch 대한수의학회 Journal of Veterinary Science 13 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 3호 9 393-405 (13 pages)
in vivo studies that have adequately demonstrated that antibodies against E2 can neutralize and protect against CSF [6,25,26]. Current knowledge of the immune system indicates that there are several, sometimes redundant, pathways by which protective immune responses against a particular pathogen can be induced [12,32,33,37]. In subunit vaccine formulations, the immunological component that... a geographical area would require permanent reduction to zero presence of the virus. It is therefore of paramount importance to develop a safe, potent, and non-infectious CSF vaccine. We have previously reported on a cost-effective CSF E2 subunit vaccine, KNB-E2, which can protect against CSF symptoms in a single dose containing 75 g of recombinant CSFV glycoprotein E2. In this study, we report on a series of animal studies undertaken to elucidate further the efficacy of KNB-E2. We found... -
Evaluation of endoscopically obtained duodenal biopsy samples from cats and dogs in an adapter-modified Ussing chamber
Isabelle Ruhnke*, John V. DeBiasio, Jan S. Suchodolski, Shelley Newman, Mark W. Musch, Jörg M. Steiner 대한수의학회 Journal of Veterinary Science 11 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 2호 17 297-307 (11 pages)
integrity. Multiple tissue responses to individual ouabain doses can be investigated in the future to characterize the viability of the tissue response. Another interesting finding was the time period until maximum current values were reached. The time period until reaching a maximum response to ouabain was 17.2 min, while responses to all other substances occurred within seconds. The lo... This study was conducted to evaluate an adapter-modified Ussing chamber for assessment of transport physiology in endoscopically obtained duodenal biopsies from healthy cats and dogs, as well as dogs with chronic enteropathies. 17 duodenal biopsies from five cats and 51 duodenal biopsies from 13 dogs were obtained. Samples were transferred into an adapter-modified Ussing chamber and sequentially exposed to various absorbagogues and secretagogues. Overall, 78.6% of duodenal samples obtained from...