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Modern Methods for Analysis of Antiepileptic Drugs in the Biological Fluids for Pharmacokinetics, Bioequivalence and Therapeutic Drug Monitoring
JuseopKang, Yoo-SinPark, Shin-HeeKim, Sang-HyunKim, Min-YoungJun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 16 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.2 1 67-82 (16 pages)
GC system [121]. Monitoring of free VPA concentration may be helpful in patient care because VPA has an unusual nonlinear protein binding charadteristics and a wide interindividual va riation [122]. Both GC and ..PAGE:5 Modern Methods for Analysis of Antiepileptic Drugs 71 HPLC methods with various detection systems are devel- oped for the determination of free VPA [116,117,123,124] and its... of AEDs in biological fluids is a necessity in order to explore pharmacokinetics, bioequivalence and TDM in various clinical situations. There are hundreds of published articles on the analysis of specific AEDs by a wide variety of analytical methods in biological samples have appears over the past decade. This review intends to provide an updated, concise overview on the modern method development for monitoring AEDs for pharmacokinetic studies, bioequivalence and therapeutic drug monitoring. -
Dendritic Cells-based Vaccine and Immune Monitoring for Hepatocellular Carcinoma
Dae-HeuiLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.1 2 11-14 (4 pages)
Medicine, 34, Amnam-dong, Seo-gu, Busan 602-703, Korea. (Tel) 82-51-990-6493, (Fax) 82-51-990-3081, 82-51-241-5458, (E-mail) dhlee@ns.kosinmed.or.kr Dendritic Cells-based Vaccine and Immune Monitoring for Hepato- cellular Carcinoma Dae-Heui Lee Department of Pharmacology, Kosin University College of Medicine, Busan 602-703, Korea Human tumors, including those of the hepatobiliary system, express... Human tumors, including those of the hepatobiliary system, express a number of specific antigens that can be recognized by T cells, and may provide potential targets for cancer immunotherapy. Dendritic cells (DCs) are rare leucocytes that are uniquely potent in their ability to capture, process and present antigens to T cells. The ability to culture sufficient numbers of DCs from human bone marrow or blood progenitors has attracted a great deal of interest in their potential utilization in human... -
A Web-based Information System for Plant Disease Forecast Based on Weather Data at High Spatial Resolution
한국식물병리학회 The Plant Pathology Journal 12 Pages
한국식물병리학회 The Plant Pathology Journal 2010, 26권 1호 6 37-48 (12 pages)
measurement of weather conditions. In this study, the original weather data were from AWSN of KMA which has more than 600 AWS's covering about 100,000 km 2 (Joo et al., 2005). The high spatial density of AWS's and the data quality control system of KMA ensure the quality of weather data in Korea. However, the AWS's are often installed at non-agricultural areas or on the roof-top of buildings (Joo... This paper describes a web-based information system for plant disease forecast that was developed for crop growers in Gyeonggi-do, Korea. The system generates hourly or daily warnings at the spatial resolution of 240 m -
Melting Characteristics of Simulated Non-combustible Radioactive Wastes in a Plasma Torch Melter System
Seung-Chul Park, Hyun-Je Cho, Cheon-Woo Kim 한국열환경공학회 열환경공학 7 Pages
한국열환경공학회 열환경공학 2011, 제 8권 3호 7 53-59 (7 pages)
of chemical cobalt and cesium tracers. The control and monitoring system, called a human machine interface (HMI), provides various displays and functions. In the beginning of the waste melting test, the torch is triggered by high frequency AC power under an argon atmosphere. Just after ignition, the power and plasma gas are automatically switched to DC and nitrogen gas, respectively. The... with the invention of the KHNP-CRI patented power supply system. Among a series of dual mode performance tests, a 24-hour melting test for typical surrogate non-combustible waste is introduced in this paper. Electrical currents and voltages of the system was well confined under the operation limits at the test. And the slag melt was well stabilized without severe abnormal behavior as well. But for safe and long-run operation, the advanced slag tapping equipment and slag level measurement device... -
Effect of lower extremity resistance exercise on gait performance in a patient with systemic lupus erythematosus with cerebral infarction and lower extremity vasculitis
Yong-seop Oh, Young-keun Woo 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2016, 제 5권 제 2호 9 106-112 (7 pages)
With a verbal cue “start” the tester monitoring the screen and the subject started the test at the same time and measurement of the accelerator and deceler- ator as soon as the subject crossed the 2 minutes mark and stopped the test once 6 minutes of data was collected. A ver- bal cue “stop” was given and both tester and subject stopped after 2 minutes more of walking. Reliability of gait... Objective: This study was conducted to investigate the effects of resistant exercise on the gait performance of a patient with systemic lupus erythematosus (SLE) patient. Design: A case study. Methods: A 30-year-old male adult who had been diagnosed with systemic lupus erythmatosus (SLE) in April 2013, right middle cerebral artery infarction, and with left hemiplegia agreed to participate in this case study. Patient was unable to walk due to being affected with adynamia. Due to developing... -
Electroencephalographic brain frequency in athletes differs during visualization of a state of rest versus a state of exercise performance
Lee Berk, Deeti Mali, Gurinder Bains, Bhagwant Madane, Jessica Bradburn, uchi Acharya, Ranjani Kumar, Savleen Juneja, Nikita Desai, Jin-h 물리치료재활과학회 Physical Therapy Rehabilitation Science 4 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2015, 제 4권 제 1호 5 28-31 (4 pages)
measurements was recorded and the mean was reported. The B-Alert ×10 telemetric electroencepha- lography (EEG), ten-channel system (Advanced Brain Monitoring Inc., Carlsbad, CA, USA) was used to acquire the EEG data. Following the 10-20 system, as shown in Figure 1, nine cerebral cortical channels (F3, Fz, F4, C3, Cz, C4, P3, POz, and P4) were used in this study. The reference electrodes... Design: Quasi-experimental design uncontrolled before and after study. Methods: EEG brain wave activity was recorded from 0-40 Hz from nine cerebral cortical scalp regions F3, Fz, F4, C3, Cz, C4, P3, POz, and P4 with a wireless telemetric EEG system. The subjects, while sitting on a chair with eyes closed, were asked to visualize themselves in a state of routine rest/relaxation and after a period of time in a state of their routine exercise performance. Results: The gamma frequency, 31-40 Hz,... -
Plyometrics and vibration: no clear winner on efficacy
R. Jeremy Hubbard, Jerrold S. Petrofsky, Everett Lohman, Lee Berk, Donna Thorpe 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2014, 제 3권 제 2호 2 86-92 (7 pages)
a less restrictive exclusion criteria may be helpful for future studies. Monitoring blood collection times for blood lactates be- came difficult. Goodwin et al. [27] cited specific peak collec- tion times (3-8 minutes) for blood lactates and we stayed within those parameters for post-exercise measures. However many subjects had to walk a notable distance from their ve- hicle or residence to the... Objective: Whole body vibration (WBV) and plyometrics are common training techniques which increase strength, blood flow, and lower body force and power. The effects these techniques have on sedentary population is unknown. It is our aim to assess the effectiveness of WBV and plyometrics on sedentary population. Design: Experimental study. Methods: Twenty-seven sedentary subjects were assigned to either the control group, jumping only group, or jumping with vibration group. Jump height (myotest... -
The use of laser Doppler blood flow to assess the effect of acute administration of vitamin D on micro vascular endothelial function in people with diabetes
Jerrold Petrofsky, Faris Alshammari, Iman Akef Khowailed, Riya Lodha, Pooja Deshpande, Praveen Rajaram, Mahendra Gaikwad, Vidhi Vadera 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2013, 제 2권 제 2호 1 63-69 (7 pages)
monitoring its effect on a weekly basis to see the rates of ..PAGE:6 68 Phys Ther Rehabil Sci 2(2) different pathways in the future. Another limitation of the study was that we did not examine brachial artery occlusion mediated vasodilation. Since brachial flow mediated dila- tion is mediate by NO as is the prolonged response of blood flow to heat, it can be predicted that this pathway would... Objective: To assess the effect of vitamin D administration on the skin blood flow response to occlusion and heat. Design: Cross-sectional study. Methods: Twenty age matched subjects; 10 who had diabetes and 10 who were controls were administered 4,000 IU of vitamin D3 for 3 weeks at breakfast. The function of the endothelial cells was evaluated in 2 ways; first, the response to 4 minutes of vascular occlusion of the skin was measured with a laser Doppler flow meter. Second, the skin blood flow... -
Effects of Ulmus davidiana Concentrate in Acute Lung Injury Model
Ye ram Rhee, Gi Beum Kim, Shang Jin Kim, Jin Shang Kim, Hyung Sub Kang 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 283 489-490 (2 pages)
monitoring of food and water intake and urine excretion. Results: Treatments with PY, EY or allantoin demonstrated positive antidiabetic activities; indicated by decreased fasting blood glucose, HbAlc, lipid peroxidation, serum total cholesterol, triglyceride, low density lipoprotein, creatinine, blood urea nitrogen, uric acid, alanine aminotransferase, aspartate aminotra nsferase, lactate... -
Korean Jeju ‘Byungkyul’, Citrus platymamma Hort.et Tanaka, Prevents Hepatocellular Carcinoma Hep3G Cells Propagation and Survival
Gyeong Eun Hong, Silvia Yumnam, Ho Jeong Lee, Suchismita Raha, Venu Venkatarame Gowda Saralamma, Jeong Doo Heo, Sang Joon Lee, Gon Sup 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 춘계학술심포지움 156 219-220 (2 pages)
(Water Lily) Extract Md. Akil Hossain, Seung-Chun Park * College of Veterinary Medicine, Kyungpook National University, Daegu 702-701, Republic of Korea Introduction: Quorum sensing is cell density dependent signaling system of bacter ial communication through diffusible chemical signal molecules that help them to control their enzyme secretion, virulence factor production and biofilm...