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Antioxidant and anticancer effect of methanolic extract of Aerva lanata Linn. against Ehrlich Ascites Carcinoma (EAC) in vivo
Raihan. Obayed, Brishti. Afrina, Bahar. Entaz, Islam. Forhadul, Rahman. Mominur, Tareq. Syed Mohammed, Hossain. Md. Aslam 경희한의학연구센터 Oriental pharmacy and experimental medicine : OPEM 7 Pages
경희한의학연구센터 Oriental pharmacy and experimental medicine : OPEM 2012, Vol.12 No.3 219-225 (7 pages)
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Effect of fermented soybean products intake on the overall immune safety and function in mice
Jae Hee Lee, Se Hee Paek, Hye Won Shin, Seung Yeon Lee, Byoung Seok Moon, Jung Eun Park, Gyeong Dong Lim, Chang Yul Kim, Yong He 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 1호 4 25-32 (8 pages)
tissue samples were collected from the thymus, spleen, and mesenteric lymph nodes from one mouse per group since these organs from seven mice per group were used for immune cell phenotyping or ex vivo production of cytokines or immunoglobulins. Tissue samples were processed for hematoxylin and eosin staining by a CRO company (Croen Research, Korea), then subjected to microscopic examination... diet of DJ, CGJ, or a mixture of unfermented raw material for 4 weeks on overall immunity and immune safety in mice. No significant alterations were observed in peripheral or splenic immune cells among groups. Enhanced splenic natural killer cell activity was observed in the DJ and CGJ groups compared with the plain diet group. T helper type-1 (Th1)-mediated immune responses were enhanced in the DJ and CGJ groups with an upregulated production ratio of IFN-γ vs. IL-4 and IgG2a vs. IgG1 in... -
CLA와 selenium의 투여가 닭의 체구성과 혈중 콜레스테롤 수준에 미치는 영향
전호진, 김진영, 임좌진, 이수한 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 10 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2005, 제 45권 제 3호 17 429-438 (10 pages)
immune cell function. Proc Soc Exp Biol Med 1995, 209, 369-375. 36. Scimeca JA, Miller GD. Potential health benefits of conjugated linoleic acid. J Am Coll Nutr 2000, 19, 470S-471S. 37. Sugano M, Tsujita A, Yamasaki M, Noguchi M, Yamada K. Conjugated linoleic acid modulates tissue levels of chemical mediators and immunoglobulins in rats. Lipids 1998, 33, 521-527. 38. Swain BK, Johri TS, Majumdar... -
The Effects of Puerariae Flos on Stress-induced Deficits of Learning and Memory in Ovariectomized Female Rats
Hyun-JungPark, Seung-MooHan, WonJuYoon, Kyung-SooKim, InsopShim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.2 3 85-90 (6 pages)
a result of stress (Kellendonk et al., 2002). In the hippocampus, stress hormones induce regression of the dendritic proc- esses and cell death, inhibit neurogenesis, and impair the ability of neurons to survive noxious stimuli such as seiz- ure, hypoxia-ischemia, metabolic poisons, hypoglycemia and oxygen radical generators (Sapolsky, 2000). The dam- age caused by a heightened stress response... Puerariae flos (PF) is a traditional oriental medicinal plant and has clinically been prescribed for a long time. The purpose of the present study was to examine the effect of PF on repeated stress-induced alterations of learning and memory on a Morris water maze (MWM) test in ovariectomized (OVX) female rats. The changes in the reactivity of the cholinergic system were assessed by measuring the immunoreactive neurons of choline acetyltransferase (ChAT) in the hippocampus after behavioral... -
Functional Connectivity Map of Retinal Ganglion Cells for Retinal Prosthesis
JangHeeYe, SangBaekRyu, KyungHwanKim, YongSookGoo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.6 4 307-314 (8 pages)
-100 ms -200 ms -300 ms Fig. 4. Spatio-temporal receptive field of ON cell (A) and OFF cell (B). (A) a. Four frames of the spatio-temporal receptive field of ON cell are shown i n succession to illustrate how the receptive field was evolved over time. Each frame shows spike-triggered average (STA) of stimulus, which preceded the action potential by the delay in milliseconds noted below eac h... was blocked by gap junction blocker, heptanol, but not by glutamatergic synapse blocker, kynurenic acid. By tracking down all the RGC pairs which showed narrow correlation, we could harvest 40 functional connectivity maps of RGCs which showed the cell cluster firing together. We suggest that finding functional connectivity map would be useful in stimulation encoding strategy for the retinal prosthesis since stimulating the cluster of RGCs would be more efficient than separately stimulating each... -
Baicalein Protects 6-OHDA-induced Neuronal Damage by Suppressing Oxidative Stress
Heh-InIm, EunjooNam, Eun-sunLee, Yu-jinHwang, YongSikKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.6 3 309-316 (8 pages)
determining cell viability using the MTT test (Fig. 5A). Mean MTT reduction levels in 20 μM 6-OHDA treated cells for 24 h reduced to 45.0±2.2% of the control level after incubating with 6-OHDA. Bai- calein pretreatment (5 or 10μM) significantly protected SH-SY5Y cells from this 6-OHDA-induced cytotoxicity, and MTT was reduced to 80.1±1.9% and 82.0±0.9%. ROS generation was measur ed by... TH-positive cell in the ipsilateral substantia nigra (SN). In addition, the levels of dopamine (DA) and DA metabolites were reduced and lipid peroxidation was increased in lesioned striatum. However, baicalein treatment reduced apomorphine-induced rotational behavior in 6-OHDA-lesioned mice, and increased TH immunoreactivity in the striatum and SN, and DA levels in lesioned striatum. Lipid peroxidation induced by 6-OHDA was also inhibited by baicalein treatment. Furthermore, when SH-SY5Y human... -
R-(-)-TNPA, a Dopaminergic D2 Receptor Agonist, Inhibits Catecholamine Release from the Rat Adrenal Medulla
Soon-PyoHong, Hong-JooSeo, Dong-YoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.5 8 273-282 (10 pages)
th e chromaffin cell membrane of the cat adrenal medulla contains a dopaminergic receptor that modulates the CA secretory process triggered by sti- mulation of the nicotinic cholinoceptor (Artalejo et al, 1985). The fact that dopamine is released in measurable amounts, together with EP and NE from the perfused cat adrenal glands in response to nicotini c stimulation, favors a role for this... The aim of the present study was to investigate the effects of R-()-2,10,11-trihydroxy-N-propylnoraporphine [R-()-TNPA], a selective agonist of dopaminergic D2 receptor and S()-raclopride, a selective antagonist of dopaminergic D2 receptor, on the secretion of catecholamines (CA) evoked by cholinergic stimulation and membrane-depolarization in the isolated perfused model of the rat adrenal gland, and also to establish its mechanism of action. R-()-TNPA (10∼100μM)... -
Inhibition of Adenosine Triphosphate-stimulated Mucin Secretion from Airway Epithelial Cells by Schizandrin
HoJinHeo, HyunJaeLee, CheolsuKim, KiHwanBae, YoungSikKim, SamSikKang, YangChunPark, YunHeeKim, UnKyoSeo, JeongHoSeok, ChoongJaeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.5 5 251-254 (4 pages)
We have tried to investigate the effects of some components from herbal medicines on mucin secretion from airway epithelial cells using a primary hamster tracheal surface epithelial (HTSE) cell culture-an established in vitro model for secretory cell metaplasia (Wasano et al, 1988). As a result, we previously reported that a few natural compounds affected mucin secretion from cultured HTSE... Schizandrae Fructus has been used for controlling respiratory allergic or inflammatory diseases in folk medicine and their components, schizandrin, schizandrin-A and gomisin-A were reported to have diverse biological effects. In this study, we investigated whether schizandrin, schizandrin-A and gomisin-A affect adenosine triphosphate (ATP)-induced mucin secretion from cultured airway epithelial cells. Confluent primary hamster tracheal surface epithelial (HTSE) cells were metabolically... -
Gene Expression Profiling in Rice Infected with Rice Blast Fungus using SAGE
한국식물병리학회 The Plant Pathology Journal 8 Pages
한국식물병리학회 The Plant Pathology Journal 2008, 24권 4호 3 384-391 (8 pages)
a given cell population. Transcriptomics is the study of the transcriptome, which is the set of all mRNA or transcripts produced in a population of cells. The transcriptome varies under stress conditions because all mRNA transcripts in a cell are a reflection of the genes that are being actively expressed under any stress conditions. Two technologies can be useful tools for transcriptomics. One of... Rice blast disease, caused by the pathogenic fungus Magnaporthe grisea, is a serious issue in rice (Oryza sativa L.) growing regions of the world. Transcript profiling in rice inoculated with the fungus has been investigated using the transcriptomics technology, serial analysis of gene expression (SAGE). Short sequence tags containing sufficient information which are ten base-pairs representing the unique transcripts were identified by SAGE technology. We identified a total of 910 tag sequences...