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전체 선택해제
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본문검색 결과만 보기
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Increased Yield of High-Purity and Active Tetrameric Recombinant Human EC-SOD by Solid Phase Refolding
Ryu. Kang, Kim. Young-Hoon, Kim. Young-Hwa, Lee. Joon-Seok, Jeon. Byeong-Wook, Kim. Tae-Yoon 한국미생물생명공학회 Journal of microbiology and biotechnology 7 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 2008, Vol.18 No.10 1648-1654 (7 pages)
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Extracellular Superoxide Dismutase (EC-SOD) Transgenic Mice: Possible Animal Model for Various Skin Changes
Kim. Sung-Hyun, Kim. Myoung-Ok, Lee. Sang-Gyu, Ryoo. Zae-Young 한국동물번식학회 Reproductive & developmental biology 6 Pages
한국동물번식학회 Reproductive & developmental biology 2006, Vol.30 No.4 229-234 (6 pages)
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Human extracellular superoxide dismutase (EC-SOD) expression in transgenic chicken
Byun. Sung June, Ji. Mi-Ran, Jang. Ye-Jin, Hwang. A-In, Chung. Hee Kyoung, Kim. Jeom Sun, Kim. Kyung-Woon, Chung. Hak-Jae, Yang. Byoung- 생화학분자생물학회 BMB reports 6 Pages
생화학분자생물학회 BMB reports 2013, Vol.46 No.8 404-409 (6 pages)
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Effects of aluminum on the reduction of neural stem cells, proliferating cells, and differentiating neuroblasts in the dentate gyrus of D-galactose-treated mice via increasing oxidative stress
Sung Min Nam, Jong Whi Kim, Dae Young Yoo, Woosuk Kim, Hyo Young Jung, Jung Hoon Choi, In Koo Hwang, Je Kyung Seong, Yeo Sung Yo 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 2호 1 127-136 (10 pages)
(EC-SOD, SOD3) forms [5,38]. Oxidative stress is one mechanism of aging related phenotype [32]. An aging-like phenotype is induced by treatment of D-galactose (D-gal) for 610 weeks [6,18,22,26]. Additional long-term treatment with Al in this model enhances the amyloidogenic pathway [18]. The hippocampus and connected areas are vulnerable to AD-like pathology and are also associated with... Aluminum (Al) accumulation increases with aging, and long-term exposure to Al is regarded as a risk factor for Alzheimer’s disease. In this study, we investigated the effects of Al and/or D-galactose on neural stem cells, proliferating cells, differentiating neuroblasts, and mature neurons in the hippocampal dentate gyrus. AlCl3 (40 mg/kg/day) was intraperitoneally administered to C57BL/6J mice for 4 weeks. In addition, vehicle (physiological saline) or D-galactose (100 mg/kg) was... -
Alcohol-induced Hyperlipidemia Is Ameliorated by Orally Administered DWP208, a Sodium Succinate Form of ZYM201
JaeYoulCho, JongwonChoi, JaeGwangPark, Young-SuYi, MuhammadJahangirHossen, HyeongminKim, JieunRo, BaeCheonCha, EunSookYoo, Jong-HoonKim, J 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.6 4 469-474 (6 pages)
EC-SOD C) reduces myocardial damage in rats subjected to coronary occlusion and 24 hours of reper- fusion. Free Radic Res Commun. 1992;17:41-47. 18. Ametaj BN, Bobe G, Lu Y, Young JW, Beitz DC. Effect of sample preparation, length of time, and sample size on quantification of total lipids from bovine liver. J Agric Food Chem. 2003;51:2105-2110. 19. Bradford MM. A rapid and sensitive method for... DWP208 is a sodium succinate form of ZYM-201 which is a triterpenoid glycoside isolated from Sanguisorba officinalis, a medicinal plant prescribed for various diseases, such as duodenal ulcers and bleeding in East Asian counties. We demonstrated that this compound is able to normalize the altered lipid metabolism induced by hyperglycemia and a high fat diet. In this study, we determined whether hyperlipidemic conditions induced with chronically treated alcohol can also be restored by DWP208.... -
Gene Expression Alterations between a Persistently PrPBSE Infected and Rubus coreanus Miquel - cured M2B Cell Line
Hyo Jin Kim, Hyun Jeong Kim, In Soon Roh, Won Yong Lee, Tae Young Suh, Hoo Chang Park, Byoung han Kim, Hyun Joo Sohn 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 138 404-405 (2 pages)
..PAGE:1 404 Korean Journal of Veterinary Science resistant to degradation by protease. There are currently no proven therapeutic agents for BSE although several researchers have been searching for anti-prion drugs. Thus, it is important to identify inhibitors with therapeutic or prophylactic activity against BSE prion. In a previous experiment, we found the new antiprion natural compounds... -
Time-dependent proteomic and genomic alterations in Toll-like receptor-4-activated human chondrocytes: increased expression of lamin A/C and annexins
SeungHeeHa, HyoungKyuKim, NguyenThiTuyetAnh, NariKim, KyungSooKo, ByoungDooRhee, JinHan 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 16 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.5 8 531-546 (16 pages)
..PAGE:1 www.kjpp.net Korean J Physiol Pharmacol 2017;21(5):531-546 531 Korean J Physiol Pharmacol 2017;21(5):531-546 https://doi.org/10.4196/kjpp.2017.21.5.531 Author contributions: S.H.H. and H.K.K. designed experiments and performed proteomics and genomics experiments. N.T.T.A. and N.K. contributed to systemic analysis of proteome data. K.S.K. and B.D.R. contributed to the advice and... Activation of Toll-like receptor-4 (TLR-4) in articular chondrocytes increases the catabolic compartment and leads to matrix degradation during the development of osteoarthritis. In this study, we determined the proteomic and genomic alterations in human chondrocytes during lipopolysaccharide (LPS)-induced inflammation to elucidate the underlying mechanisms and consequences of TLR-4 activation. Human chondrocytes were cultured with LPS for 12, 24,and 36 h to induce TLR-4 activation. The... -
Ellagic acid plays a protective role against UV-B-induced oxidative stress by up-regulating antioxidant components in human dermal fibroblasts
BeomyeolBaek, SuHeeLee, KyunghoonKim, Hye-WonLim, Chang-JinLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.3 6 269-277 (9 pages)
..PAGE:1 www.kjpp.net Korean J Physiol Pharmacol 2016;20(3):269-277 269 Korean J Physiol Pharmacol 2016;20(3):269-277 http://dx.doi.org/10.4196/kjpp.2016.20.3.269 Author contributions: B.B. and S.H.L. performed the experiment and analyzed the data. H.W.L. supervised and coordinated the experiment. K.K. and C.J.L. designed the research and wrote the manuscript. This is an Open Access article... Ellagic acid (EA), an antioxidant polyphenolic constituent of plant origin, has been reported to possess diverse pharmacological properties, including anti-inflammatory, anti-tumor and immunomodulatory activities. This work aimed to clarify the skin anti-photoaging properties of EA in human dermal fibroblasts. The skin anti-photoaging activity was evaluated by analyzing the reactive oxygen species (ROS), matrix metalloproteinase-2 (MMP-2), total glutathione (GSH) and superoxide dismutase (SOD)... -
Synergistic antidiabetic activity of quercetin and resveratrol in animal model of type-1 diabetes
Ye ram Rhee, Mahbubur Rahman, Shang Jin Kim, Jin Shang Kim, Hyung Sub Kang 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 285 490-491 (2 pages)
..PAGE:1 490 Korean Journal of Veterinary Science [7] Matute-Bello, G., Frevert, C. W., Martin, T. R. 2008. Animal models of acute lung injury. Am. J. Physiol. Lung Cell Mol. Physiol. 295: L379L399. P-202 Anti-diabetic effects of Korean yam (Dioscorea batatas) and its active constituent, allantoin, in a rat model of type-1 diabetes Yeram Rhee, Md. Mahbubur Rahman, Shang-Jin Kim, Jin-Shang...