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총 131건 검색
본문검색 결과만 보기
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Feasibility of On-chip Detection of Endotoxin by LAL Test
Lee. Eun-Kyu, Suh. Chang-Woo, Hwang. Sang-Youn, Park. Hyo-Jin, Seong. Gi-Hoon, Ahn. Yoo-Min, Kim. Yang-Sun 한국생물공학회 Biotechnology and bioprocess engineering 5 Pages
한국생물공학회 Biotechnology and bioprocess engineering 2004, Vol.9 No.2 132-136 (5 pages)
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Correlation of age of pigs and endotoxin in respirable dust in swine barns with pigs’ immune response
Katharine Roque, Yong Heo, Eun Seob Song, Ah Rang Cho, Yun Gyeong Kim, Jae Hee Lee, Ravi Gautam, So Jung Sin, Chang Yeol Kim, Hyung Ah Ki 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 380 397-398 (2 pages)
a biologically active aerosol. Endotoxin in particular has been associated with various pulmonary illnesses. We investigated the relationship of endotoxin level in dust with the various immunological markers of pigs from ten different pig farms in Korea. Materials and Methods: Concentrations of total and respirable dust (PM10) inside pig farms were collected using PVC membrane filters and... -
Association between endotoxin levels in dust from indoor swine housing environments and the immune responses of pigs
Katharine Roque, Kyung Min Shin, Ji Hoon Jo, Gyeong Dong Lim, Eun Seob Song, So Jung Shin, Ravi Gautam, Jae Hee Lee, Yeon Gyeong Kim, Ah 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 3호 2 331-338 (8 pages)
endotoxin exposure than isolation of Gram-negative bacteria. Hence, to test the hypothesis that exposure to endotoxins in natural husbandry settings can alter the immune responses of pigs, we measured endotoxin levels in several swine farms and assessed the relationship of endotoxin level with the immunological profiles of the swine in these farms. Materials and Methods Pig farms and blood... Indoor animal husbandry environments are inevitably contaminated with endotoxins. Endotoxin exposure is associated with various inflammatory illnesses in animals. This cross-sectional study evaluated the relationship between the degree of endotoxin exposure and the cellular and humoral immune profiles of fattening pigs. Blood samples were taken from the jugular vein of 47 pigs from ten pig farms in Korea. Whole blood cell counts and plasma immunoglobulin (Ig) classes were determined.... -
Relationship between chicken cellular immunity and endotoxin levels in dust from chicken housing environments
Katharine Roque, Kyung-Min Shin, Ji-Hoon Jo, Hyoung-Ah Kim, Yong Heo 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 2호 6 173-177 (5 pages)
B cells was lower in layers from farms with higher endotoxin levels than those from locations with lower endotoxin levels. Overall, these results suggest a probable negative association between dust endotoxin levels and cell-mediated immunity in chickens. Keywords: cellular immunity, chicken, endotoxin, dust, interferon- Introduction Animal welfare has been continuously discussed since the Worl... biochemical agents in animal husbandry indoor environments are known to promote the occurrence of various illnesses among workers and animals. The relationship between endotoxin levels in dust collected from chicken farms and various immunological markers was investigated. Peripheral blood was obtained from 20 broiler chickens and 20 laying hens from four different chicken farms in Korea. Concentrations of total or respirable dust in the inside the chicken farm buildings were measured using a... -
Influence of endotoxin induced fever on the pharmacokinetics of intramuscularly administered cefepime in rabbits
Ayman Goudah, Samar M. Mouneir, Jae-Han Shim, A. M. Abd El-Aty 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 2호 10 151-155 (5 pages)
enzyme activities [14], which can alter the pharmacokinetics of certain drugs [3]. For example, an increased volume of distribution for penicillin-G has been reported in rabbits, pigs and dogs during endotoxin-induced fever [26]. However, pigs, dogs and rabbits showed higher blood concentrations of sulphathiazole, sulphadimidine and gentamicin during endotoxin-induced fever [26]. Therefore, animal... in the elimination halflife by 21.8% in the febrile rabbits compared to healthy animals. In addition, the infection significantly increased the peak plasma concentrations by 11.9%, the mean residence time by 19.9%, the area under the plasmaconcentration- time curve by 53.6% and the area under the moment curve by 62.3%. In conclusion, the endotoxin-induced febrile state produced significant changes in the plasma levels as well as some of the pharmacokinetic variables of cefepime in rabbits. -
Endotoxin-induced Acute Lung Injury is Mediated by PAF Produced via Remodelling of Lyso PAF in the Lungs
YoungManLee, TeoanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.3 6 219-226 (8 pages)
4: 219-226， June， 2000 Endotoxin-induced Acute Lung Injury is Mediated by PAF Produced via Remodelling of Lyso P AF in the Lungs Y oung Man Lee， and Teoan Kim Department of Physiology， School of Medicine， Catholic University of Taegu-Hyosung， Taegu 705-718， Korea In order to elucidate the role of platelet activating factor (PAF) in the acute lung injury induced by endotoxin (ETX) ，... In order to elucidate the role of platelet activating factor (PAF) in the acute lung injury induced by endotoxin (ETX), activities of phospholipase A2, lyso PAF acetyltransferase and oxidative stress by neutrophilic respiratory burst were probed in the present study. To induce acute lung injury, 100μg of E.coli ETX (type 0127; B8) was instilled directly into the tracheae of Sprague-Dawley rats. Five hours after the ETX instillation, induction of acute lung injury was confirmed by lung leak... -
Depression of L-type Ca2+ and Transient Outward K+ Currents in Endotoxin-treated Rat Cardiac Myocytes
KyuSangPark, BooSooLee, InDeokKongJoongWooLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.6 11 623-630 (8 pages)
endotoxin treated myocytes (16.51.5 pAfpF， P <0.05 was considered as significant1y different. Ca21 and K Test potential (mV) (B) 50 40 30 20 10 0 -40 -30 -20 -10 RESULTS L-te Ca2 十current of control and endotoxin-treated myocytes Fig. 1. L-type Ca2+ curents in rat ventricular myocytes. Ca2+ curents were recorded using the whole cell patch clamp technique. Cells were dialyzed with Cs +... in vitro also attenuated ICa,L (8.40.4 pA/pF, P＜0.01). The amplitude of Ito on depolarization to 60 mV was reduced in endotoxin treated myocytes (16.51.5 pA/pF, P＜0.01, ex vivo; 20.00.9 pA/pF, P＜0.01 , in vitro) compared to normal myocytes (control; 24.71.0 pA/pF). There was no voltage shift in steady-state inactivation of ICa,L and Ito between groups. These results suggest that endotoxin reduces Ca2 and K currents of rat cardiac myocytes, which may lead to cardiac dysfunction. -
The Enhancement of Endotoxin-Induced Nitric Oxide Production by Elevation of Glucose Concentration in Macrophage
HyunGooWoo, Yi-SookJung, EunJooBaik, Chang-HyunMoon, SooHwanLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.4 10 447-454 (8 pages)
up to 10 mM. Glucosamine marginally increased the endotoxin-induced nitrite release in both control and high glucose treated group. 6-diazo-5-oxonorleucine (L-DON) and azaserine， glutamine: fructose- 6-phosphate amidotransferase (GFAT) inhibitors， significant1y diminished the augmentation effect of high glucose on endotoxin-induced NO production. On the other hand， negative modulation of GFAT... The production of nitric oxide (NO) and the expression of inducible nitric oxide synthase (iNOS) are known to be modulated by a variety of factors. Recent study showed that endotoxin-induced NO synthesis and iNOS expression were greatly enhanced by elevation of extracellular glucose concentration in murine macrophages. Although this was suggested to be due to the activation of protein kinase C (PKC) via sorbitol pathway, there was lack of evidence for this speculation. This study was performed... -
의과대학생을 위한 임상미생물 멀티미디어 강의의 개발과 평가
오승환(Seung Hwan Oh), 이선민(Sun Min Lee), 김형회(Hyung Hoi Kim), 이은엽(Eun Yup Lee), 정해진(Hae Jin Jeong), 이상엽(Sang Yeoup Lee), 김성수(Sung Soo Kim) 한국의학교육학회 Korean Journal of Medical Education 10 Pages
한국의학교육학회 Korean Journal of Medical Education 2006, 제 18권 제 2호 6 161-170 (10 pages)
E. coli, Klebsiella, Enterobacter, Proteus, Serratia, Citrobacter Typhoid fever, Endotoxin shock 6. Antimicrobial resistance Antimicrobial susceptibility testing Extended spectrum betalactamase 7. Other bacteria Glucose nonfermenters, Vibrio, Hemophilus, Branhamella catarrhalis, Neisseria, Legionella, Chlamydia, Mycoplasma, Classification of bacteria 8. Fungi Specimen processing and diagnosis Host...