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The Uptake of 2-deoxy-D-glucose (2dGlc) by the Endogenous Sugar Transporter(s) of Spodoptera frugiperda Clone 21-AE Cells and the Inhibition of 2dGIc Transport in the Insect Cells by Fructose and Cytoc halasin B
Lee. Chong-Kee 대한의생명과학회 The Journal of biomedical laboratory sciences 5 Pages
대한의생명과학회 The Journal of biomedical laboratory sciences 2003, Vol.9 No.4 177-181 (5 pages)
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Cross-reactivity of Human Polyclonal Anti-GLUT1 Antisera with the Endogenous Insect Cell Glucose Transporters and the Baculovirus-expressed GLUT1
Lee. Chong-Kee 대한의생명과학회 The Journal of biomedical laboratory sciences 6 Pages
대한의생명과학회 The Journal of biomedical laboratory sciences 2001, Vol.7 No.4 161-166 (6 pages)
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Cytotoxicological Effect of Tebufenozide, an Insect Growth Regulator (IGR): Stimulation of Filamentous Actin Reorganization and Enhancement of Hsp27 Expression in Drosophila Kc Cells
JeeNaHwang, Hwa-JinJung, YoungRokSeo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.6 10 351-354 (4 pages)
an ecdysone-inducible APT-binding cassette transporter capable of repressing ecdysone-mediated gene acti- vation. PNAS 97: 9519 －9524, 2000 Li GC, Li L, Liu YK, Mak JY, Lee C. Thermal response of rat fibroblasts stably transfected with the human 70-kDa heat shock protein-encoding genes. Proc Natl Acad Sci USA 88: 1681 －1685, 1991 Marks EP. Insect tissue culture: An overview. Annu Rev Entomol... The cytotoxicological responses to insect growth regulator (IGR), using tebufenozide as ecdysteroid mimic, were investigated in Drosophila Kc cells. Treatment of Kc cells with tebufenozide showed significant growth inhibition and striking morphological changes including aggregation and elongation of the cells. In order to understand the cellular mechanism underlying the response of Drosophila cells to tebufenozide, immunofluorescence microscopy was performed. We found that treatment of Kc cells... -
PCR detection of Giardia lamblia in Stray dogs in Kyunggi Province, Korea
Yun Dong Choi, Do Young Kim, Min Hyeok Gong, Ye Eul Lee, Ju Hee Son, Ji Jeong Lee, Tae Wan Kim 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 93 255-256 (2 pages)
the NCBI Blast. The specific single nucleotide polymorphisms (SNPs) of bcsp31, fbaA, ssrA, omp25, entE, ABC transporter, H, rpoB, RS00005, glk, BAb-RB51, rplV, clpX and rpsL gene were analyzed using CLC Main Workbench software version 6.0 (Insilicogen Inc, south Korea) and their primer size including specific SNP site were synthesized as about 200bp. The PCR assay was performed to annealing... -
Effects of Fluvastatin on the Pharmacokinetics of Repaglinide: Possible Role of CYP3A4 and P-glycoprotein Inhibition by Fluvastatin
Chong-KiLee, Jun-ShikChoi, JoonSeokBang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.3 10 245-251 (7 pages)
oral BA of repaglinide, which may be mainly attributable to the inhibition of the CYP3A4-mediated metabolism of repaglinide in the small intestine and/or liver, to the inhibition of the P-gp efflux transporter in the small intestine and/or to the reduction of TBC of repaglinide by fluvastatin. The study has raised the awareness of potential interactions during concomitant use of repaglinide wi... be mainly attributable to the inhibition of the CYP3A4-mediated metabolism of repaglinide in the small intestine and/or liver, to the inhibition of the P-gp efflux transporter in the small intestine and/or to the reduction of TBC of repaglinide by fluvastatin. The study has raised the awareness of potential interactions during concomitant use of repaglinide with fluvastatin. Therefore, the concurrent use of repaglinide and fluvastatin may require close monitoring for potential drug interactions. -
Prolyl 4 Hydroxylase: A Critical Target in the Pathophysiology of Diseases
RaviKant, AnjanaBali, NirmalSingh, AmteshwarSinghJaggi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.2 1 111-120 (10 pages)
methyloxalylglycine (DMOG) as P4H enzyme inhibitors. The treatment with these inhibi tors and short duration hy- poxia were found to induce th e expression of different pro- teins including glucose transporter 1 (GLUT1), nitric oxide synthase (NOS) and heme oxygenase-1 (HO-1). In conjunc- tion with these changes in gene expression and HIF-P4H inhibition, increased myocyte viability was observed... Prolyl 4 hydroxylases (P4H) are iron- and 2-oxoglutamate-dependent dioxygenase enzymes and hypoxia-inducible transcription factor (HIF)-P4Hs play a critical role in the regulating oxygen homeostasis in the local tissues as well in the systemic circulation. Over a period of time, a number of prolyl hydroxylase inhibitors and activators have been developed. By employing the pharmacological tools and transgenic knock out animals, the critical role of these enzymes has been established in the... -
Effects of Dopamine on Intracellular pH in Opossum Kidney Cells
KyungWooKang, YungKyuKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.3 11 187-191 (5 pages)
H +-ATPase transporter (Aronson, 1983; Alpern, 1990; Krapf & Alpern, 1993; Alpern & Rector Jr, 1996). The NHE activity is influenced by the systemic and/or cellular acid-base status (Ambuhl et al, 1996). NHE is a ubiquitous transporter present in all mammalian cell types, and func- tions to regulate intracellular pH (pHi) by removing one intracellular H + for one inwarded-directed Na + whose... Na/H exchanger (NHE) has a critical role in regulation of intracellular pH (pHi) in the renal proximal tubular cells. It has recently been shown that dopamine inhibits NHE in the renal proximal tubules. Nevertheless, there is a dearth of information on the effects of long-term (chronic) dopamine treatment on NHE activities. This study was performed to elucidate the pHi regulatory mechanisms during the chronic dopamine treatments in renal proximal tubular OK cells. The resting pHi... -
Proteomic Changes in the Sound Vibration-Treated Arabidopsis thaliana Facilitates Defense Response during Botrytis cinerea Infection
Ritesh Ghosh, Bosung Choi, Young Sang Kwon, Tufail Bashir, Dong-Won Bae, Hanhong Bae 한국식물병리학회 The Plant Pathology Journal 14 Pages
한국식물병리학회 The Plant Pathology Journal 2019, 35권 6호 7 609-622 (14 pages)
(Atgox3 and Athaox2) after inoculation with P. syringae (Rojas et al., 2012). Alterations in amino acid metabolism also in- fluence plant defense responses. Arabidopsis lht1 (lysine histidine transporter 1) mutant that constitutively expresses PR1 and has reduced contents of glutamine, alanine, and proline, showed enhanced resistance against diverse fungal and bacterial pathogens (Liu et... Sound vibration (SV) treatment can trigger various molecular and physiological changes in plants. Previously, we showed that pre-exposure of Arabidopsis plants to SV boosts its defense response against Botrytis cinerea fungus. The present study was aimed to investigate the changes in the proteome states in the SV-treated Arabidopsis during disease progression. Proteomics analysis identified several upregulated proteins in the SVinfected plants (i.e., SV-treated plants carrying Botrytis...