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Developmental changes in GABAA tonic inhibition are compromised by multiple mechanisms in preadolescent dentate gyrus granule cells
SudipPit, GyuSeungLee, JinBongPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.6 15 695-702 (8 pages)
multiple mechanisms in preadolescent dentate gyrus granule cells Sudip Pandit #,†, Gyu Seung Lee #,¶, and Jin Bong Park* Department of Physiology, School of Medicine and Brain Research Institute, Chungnam National University, Daejeon 35015, Korea ARTICLE INFO Received August 28, 2017 Revised September 20, 2017 Accepted September 21, 2017 *Correspondence Jin Bong Park E-mail: jinbong @cnu.ac.kr... in the presence of exogenous GABA. Itonic sensitivity to L-655,708, a GABAAR α5 subunit inverse agonist, gradually decreased during the preadolescent period in the presence of NPA or exogenous GABA. Finally, Western blot analysis showed that the expression of the GABAAR α5 subunit in the dentate gyrus gradually decreased with age. Collectively, our results suggested that the Itonic regulation of altered GATs is under the final tune of GABAAR α5 subunit activation in DGGCs at different ages. -
Ahcyl2 upregulates NBCe1-B via multiple serine residues of the PEST domain-mediated association
PilWhanPark, JeongYealAhn, DongkiYang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.4 13 433-440 (8 pages)
is essential for the Original Article Ahcyl2 upregulates NBCe1-B via multiple serine residues of the PEST domain-mediated association Pil Whan Park 1,#, Jeong Yeal Ahn 1,#, and Dongki Yang 2,* 1Department of Laboratory Medicine, Gachon University Gil Hospital, Incheon 21565, 2Department of Physiology, College of Medicine, Gachon University, Incheon 21936, Korea ARTICLE INFO Received April 25,... Inositol-1,4,5-triphosphate [IP3] receptors binding protein released with IP3 (IRBIT) was previously reported as an activator of NBCe1-B. Recent studies have characterized IRBIT homologue S-Adenosylhomocysteine hydrolase-like 2 (AHCYL2). AHCYL2 is highly homologous to IRBIT (88%) and heteromerizes with IRBIT. The two important domains in the N-terminus of AHCYL2 are a PEST domain and a coiled-coil domain which are highly comparable to those in IRBIT. Therefore, in this study, we tried to... -
Mathematics using multiple senses: Developing finger gnosis with three- and four-year-olds in an era of multi-touch technologies
Nathalie Sinclair, David Pimm 환태평양유아교육연구학회 Asia-Pacific journal of research in early childhood education 11 Pages
환태평양유아교육연구학회 Asia-Pacific journal of research in early childhood education 2015, Vol.9 No.3 7 99-110 (11 pages)
overlooked. Further analysis of the affective flow in this episode would provide even greater insight into the dynamic nature of the process. ..PAGE:11 Mathematics using Multiple Senses: Developing Finger Gnosis with Three- and Four-year-olds in an Era of Multi-touch Technologies 109 References Austin, J. (1962). How to do things with words. Cambridge, MA: Harvard University Press. Baroody,... In this paper, we explore a richer sense of finger gnosis (finger knowledge) with respect to three- and four-year-olds’ interactions with a novel iPad application (TouchCounts), focusing on their responses to an “inverse subitising” task. The direct and tactile nature of their engagement with TouchCounts leads to a striking shift from incrementing using the index finger to deployment of several fingers all-at-once (in a cardinal touch gesture) to achieve a given target number that is then... -
A Comparison of Three Bayesian Point Estimates for Cross-Classified Multiple Membership Growth Curve Modeling
Chung Hyewon, Jeon Hyeonjeong, Park Soyoung 한국교육학회 교육학연구 26 Pages
한국교육학회 교육학연구 2021, 59권 7호 7 167-192 (26 pages)
is because Bayesian analysis assumes that a parameter arises from a distribution of possible values. However, it is possible to examine the expected value mean, median or mode of the posterior distribution to provide a point estimate as the correspondence between the posteriordistribution and frequentistinferentialprocedures. Bayesian inference requires the specification of prior distributions for... mode estimates of the between-school variances in the intercept and slope were substantially overestimated. In general, with the inverse Wishart prior, the Markov chain Monte Carlo (MCMC) posterior median is recommended for cross-classified multiple membership growth curve modeling, except under certain conditions. With the uniform prior, the MCMC mode is recommended for estimating cross-classified multiple membership growth curve modeling rather than the MCMC posterior mean or posterior median. -
An Analysis of Unit Assessments in Elementary-School Mathematics Textbooks
Nam Jinyoung 경인교육대학교 교육연구원 교육논총 21 Pages
경인교육대학교 교육연구원 교육논총 제 41권 특별호 8 133-153 (21 pages)
3) 2) 1-2 means (first grade)-(second semester) ..PAGE:5 An Analysis of Unit Assessments in Elementary-School Mathematics Textbooks 137 Ⅲ. Results 1. Mathematical Content The main lessons assessed in each item are presented in Table 3. Some, such as those in Figure 1, assess content taught over multiple main lessons, such as asking students to sort figures with the same area. The areas of a... The 2015 revised elementary-school curriculum reduced the number of standardized tests in favor of course-centered assessments. As a consequence, textbook unit assessments have become more central and important. The present study analyzes unit assessments in elementary-school mathematics textbooks, developed in accordance with the 2015 revised curriculum, to determine whether they provide even coverage of mathematical content and competencies. The findings show that main lesson content is... -
뇌기반 기독교교육의 새로운 모형 연구
한국종교교육학회 종교교육학연구 2016, 제 51권 6 129-151 (23 pages)
작업이고, 미래 지향적 방식은 ‘상응화’(correspondence) 작업에 해당한다.65) 행동의 단계가 성공적으로 마무리되 면, 네 단계 교수학습 과정은 전체적인 순환을 또다시 반복하게 된다. Ⅴ. 결론 신경과학의 급속한 발달은 인간의 학습, 또는 인지처리과정과 관계가 있거나 관심을 갖 고 있는 분야에 새로운 가능성을 제시하고 있는 게 사실이다. 이런 발전의 영향으로 심리 철학부터 인지과학, 그리고 더 나가서... 신경과학의 급격한 발전으로 기독교교육은 물론 인접 학문까지 과거에 예상하지 못한 변화를겪고 있다. 특히 최근 학습자의 전인적 측면에 관심을 갖고 있는 기독교교육은 신경과학과의 학제적 대화를 통해서 뇌의 특성과 기능에 주목하게 되었다. 신경과학적 논의가 기독교교육에 함의하는 연구결과들을 중심으로 뇌기반 기독교교육의 모형을 구성하는 것을 목적으로 삼고 있는 이 글은 일차적으로 뇌의 특성화된 기능을 강조하는 뇌기반 기독교교육 모형들을 검토했다. 계속해서기존 모형들의 대안이 될 수 있는 신경과학의 주요 논제들... -
SNP genetic polymorphisms of MDR-1, CYP1A2 and CYPB11 genes in four canine breeds upon toxicological evaluation
Rosa Gagliardi, Silvia Llambí, M. Victoria Arruga 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 3호 4 273-280 (8 pages)
to principal component analysis, this method provides a means of displaying or summarising a set of data in three-dimensional graphical form. The analysis is conducted from a contingency table according to breed in which the rows are composed of the dependent variable (breed) and the columns are the set of explanatory variables (alleles). The analysis mode is multiple correspondence. The... The fields of pharmacogenetics and pharmacogenomics have become increasingly promising regarding the clinical application of genetic data to aid in prevention of adverse reactions. Specific screening tests can predict which animals express modified proteins or genetic sequences responsible for adverse effects associated with a drug. Among the genetic variations that have been investigated in dogs, the multidrug resistance gene (MDR) is the best studied. However, other genes such as CYP1A2 and... -
Dehydroepiandrosterone and cortisol concentrations in the cerebrospinal fluid of dogs
Paolo Mongillo , Marco Bernardini , Elisa Prana , Federica Balducci , Gianfranco Gabai , Lieta Marinelli 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 4 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2017, 제 57권 제 1호 8 47-50 (4 pages)
b was not dif- ferent from zero, indicating good correspondence between observed and expected concentrations. The results of the intra- and inter-assay precision test are expressed as coefficients of variation. ..PAGE:3 Dehydroepiandrosterone and cortisol concentrations in the cerebrospinal fluid of dogs 49 DHEA and DHEA-S concentrations in the CSF, which were both approximately twice as high in... -
삼정환의 랫드를 이용한 90일 반복 경구투여 독성시험
김민지(Min-Jee Kim), 이명종(Myeong-Jong Lee), 김호준(Hojun Kim) 한방비만학회 대한한방비만학회지 14 Pages
한방비만학회 대한한방비만학회지 2018, 제 18권 제 1호 5 36-49 (14 pages)
SJH extract during the study period. Results: There were no toxicologically significant changes in mortalities, clinical signs, body weight gains, food consumption, ophthalmologic findings, urine analysis, hematology, se- rum biochemistry, necropsy findings, organ weights, histological markers in any of rats tested. Conclusions: The NOAEL of the modified SJH extract in male rats and no observed... -
비만 치료 한약 무작위 대조 임상시험에서의 음식 섭취량과 운동량 실태분석
김두희(Doo Hee Kim), 신우석(Woo Suk Shin), 박원형(Won Hyung Park), 차윤엽(Yun Yeop Cha), 송윤경(Yun Kyung Song), 안민윤(Min Youn Ahn), 고성규(Seong Gyu Ko) 한방비만학회 대한한방비만학회지 8 Pages
한방비만학회 대한한방비만학회지 2013, 제 13권 제 2호 2 58-65 (8 pages)
by multiple choice survey that are designed to help patients to diagnose themselves more accurately leading to less bias. For the exercise side, it is highly recommended to confine the exercises to walking only so as to quantify the amount of physical activity more easily by using pedometer. Key Words: Randomized controlled trial, Obesity, Food intake, Physical activity Correspondence to:...


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