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DESIGN OF A PWR POWER CONTROLLER USING MODEL PREDICTIVE CONTROL OPTIMIZED BY A GENETIC ALGORITHM
NA. Man-Gyun, HWang. In-Joon 한국원자력학회 Nuclear engineering and technology : an international journal of the Korean Nuclear Society 12 Pages
한국원자력학회 Nuclear engineering and technology : an international journal of the Korean Nuclear Society 2006, Vol.38 No.1 81-92 (12 pages)
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Efficient Management Design for Swimming Exercise Treatment
KyunghunKim, TaewonKyung, WonhyunKim, ChungsickShin, YoungjaeSong, MooYeolLee, HyunwooLee, YongchanCho 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.6 14 497-502 (6 pages)
73 swimming were indexed and we ighted values and priority ranking for these indices was analyzed. In addition, using the same index, we tried to model a system to systemati- cally manage patients based on different priority rankings; that is, we tried to model a system that provided patients with optimized exercise therapy. The modeling was done in real-time based on a dispersion environment... muscular and cardiovascular diseases. The present study sought to design a swimming-based exercise treatment management system. A survey questionnaire was completed by participants to assess the prevalence of muscular and cardiovascular diseases among adult males and females participating in swimming programs at sport centers in metropolitan regions of country. Using the Fuzzy Analytic Hierarchy Process (AHP) technique, weighted values of indices were determined, to maximize participant clarity.... -
Polymorphism in the serotonin transporter protein gene in Maltese dogs with degenerative mitral valve disease
Chang-Min Lee, Jae-Ik Han, Min-Hee Kang, Seung-Gon Kim, Hee-Myung Park 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 1호 16 129-135 (7 pages)
1.1, GA341 model score ＞ 0.7, E-value ＜ 0.0001, and z-discrete optimized protein energy ＜ 0. All prediction model results were within the reliable ranges in ModWeb. The 3D structure of the native model was generated by using RaptorX (Fig. 1). The SERT gene contains 630 amino acid residues. Of these, 599 amino acid residues (88%) were modeled, and 81 to 83 amino acid residues (12%13%) of... in five exons. Protein structure and function of the five nonsynonymous genetic variations were predicted. Three of the five polymorphisms were predicted to be probable causes of damage to protein function and confirmed by protein structure model verification. This study identified six polymorphisms of the SERT gene in Maltese dogs with DMVD, suggesting an association between the SERT gene and canine DMVD. This is the first study of SERT mutation in Maltese dogs with DMVD and is considered a... -
Porcine circovirus type 2 increases interleukin-1beta and interleukin-10 production via the MyD88-NF-kappa B signaling pathway in porcine alveolar macrophages in vitro
Junyuan Han, Shuxia Zhang, Yaqun Zhang, Mengmeng Chen, Yingjun Lv 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 2호 8 183-191 (9 pages)
h and were then inoculated with PCV2 virus after washing twice with PBS buffer. The siRNA dose was optimized in pilot experiments, and no appreciable cellular toxicity was observed. Experimental design The PAMs were divided into four groups as follows: Group 1, inoculation with PCV2 virus at 1 × 10 6.5 TCID50; Group 2, inoculation with MyD88 siRNA and PCV2 virus at 1 × 10 6.5 TCID50; Group... Porcine alveolar macrophages (PAMs) represent the first line of defense in the porcine lung after infection with porcine circovirus type 2 (PCV2) via the respiratory tract. However, PCV2 infection impairs the microbicidal capability of PAMs and alters cytokine production and/or secretion. At present, the reason for the imbalance of cytokines has not been fully elucidated, and the regulatory mechanisms involved are unclear. In this study, we investigated the expression levels and regulation of... -
Hsp70 and HSF-1 expression is altered in the tissues of pigs transported for various periods of times
Miao Zhang, Zhenhua Yue, Zhijun Liu, Ali Islam, Buriro Rehana, Shu Tang, Endong Bao*, Jorg Hartung 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2012, 제 13권 제 3호 6 253-259 (7 pages)
152-bp product) and GAPDH (forward primer, 5´-GAAGGTCGGAGTGAAC GGAT-3´; reverse primer, 5´-CATGGGTAGAATCATACTG GAACA-3´; 149-bp product) were synthesized by Invitrogen (USA) and had an optimized annealing temperature of 60 o C. Measurement of Hsp70 mRNA levels by fluorescent quantitative real-time PCR (FQㆍRT-PCR) Each cDNA sample (2 L, 25× dilution in ribonuclease- free water) was... The aim of this study was to assess changes of Hsp70 and HSF-1 protein and mRNA expression in stress-sensitive organs of pigs during transportation for various periods of time. Twenty pigs were randomly divided into four groups (0 h, 1 h, 2 h, and 4 h of transportation). A significant increased activity of AST and CK was observed after 1 h and 2 h of transportation. Histopathological changes in the heart, liver, and stomach indicated that these organs sustained different degrees of injury. Hsp70... -
Optimization of culture media of pathogenic Mycoplasma hyopneumoniae by a response surface methodology
Mi-Hyun Hwang, Dereje Damte, Min-Hee Cho, Young-Hoan Kim, Seung-Chun Park* 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2010, 제 11권 제 4호 8 327-332 (6 pages)
extract, and horse and porcine sera, were selected for further optimization using a central composite design (CCD) of RSM. The experimental results were fitted into a second order polynomial model equation. Estimated optimal c o n d i t i o n o f t h e f a c t o r s for maximum production of mycoplasmal protein (i.e., triple-fold increase from 0.8 mg/L produced by basal mycoplasma media to... central composite design (CCD) of RSM. The experimental results were fitted into a second order polynomial model equation. Estimated optimal condition of the factors for maximum production of mycoplasmal protein (i.e., triple-fold increase from 0.8 mg/L produced by basal mycoplasma media to 2.5 mg/L) was 10.9% fresh yeast extract, 15% horse serum, and 31.5% porcine serum (v/v). For the optimized conditions, a 2.96 mg/L experimental result was observed, similar to the estimated optimal conditions... -
Bioavailability of the amino acid-attached prodrug as a new anti-HIV agent in rats
Kyung-Ae Chae, Hee-Jung Cho, Ji-Min Sung, Hee Lee, Dong-Cheol Seo, Jin-Suk Kim, Ho-Chul Shin 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 3호 10 263-267 (5 pages)
of optimized protein therapy by bioconjugation as a polymeric DDS. Anticancer Agents Med Chem 2006, 6, 251-258. 2.Arnold E, Das K, Ding J, Yadav PN, Hsiou Y, Boyer PL, Hughes SH. Targeting HIV reverse transcriptase for anti- AIDS drug design: structual and biological consideration for chemotherapeutic strategies. Drug Des Discov 1996, 13, 29- 47. 3.Bardsley-Elliot A, Perry CM. Nevirapine: a review... The primary objective of this study was to compare the pharmacokinetics of a new anti-human immunodeficiency virus agent 1-(2-amino-pyridin-4-ylmethyl)-6-(3,5-dimethylbenzoyl)- 5-isopropyl-1H-pyrimidine-2,4-dione (VP-0502) with its amino acid prodrug alanine amide of VP-0502 (VP-0502AL), following intravenous and oral administrations to rats. The plasma concentrations of both analytes were analyzed via high-performance liquid chromatography coupled with photodiode-array detection (HPLC-DAD).... -
Angiogenesis effects of nerve growth factor (NGF) on rat corneas
Kangmoon Seo, Jongil Choi, Myungjin Park, Changhun Rhee 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2001, 제 2권 제 2호 10 125-130 (6 pages)
a computer program. If needed, digitized images were optimized for analysis by erasing nonvascular structures and completing vascular profiles. The contiguous circumferential zone of neovascularization was measured as clock hours with a 360 o reticule (where 30 o of arc equalled 1 clock hour). The area of corneal neovascularization was determined with a reticule by measuring the vessel length(L)... This study was performed to evaluate the effects of nerve growth factor (NGF) upon angiogenesis in the rat cornea, to examine its possible application as an alternative angiogenic inducer and to provide basic data for further studies. Angiogenesis was induced by cornea micropocket assay, as previously described. Eight of thirty two eyes of Sprague-Dawley rats were randomly assigned to one of four groups, namely, a non-NGF group (Group 0), a 0.5 ng of NGF group (Group 0.5), a 1.0 ng of NGF group... -
Physiology,Pharmacology,Chemistry : Comparison of Linear and non-Linear equation for the calibration of roxithromycin analysis using Liquid chromatography/mass spectrometry
Jong Hwan Lim , Hyo In Yun 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 7 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2010, 제 50권 제 1호 2 11-17 (7 pages)
with a hexapole ion guide. The instrument was tuned and optimized for the transmission of the nominal positive ion of roxithromycin (m/z 837.5). The optimal condition for the analysis of roxithromycin employed pneumatic nebulization with nitrogen (45 p.s.i.) and a counterflow of nitrogen (9 L/min) heated to 350 oC for the nebulization and desolvation of the introduced liquid. Mass spectrometer was...