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고지방식이로 유도된 비만형 동물모델에서 부자 물추출물의 비만 및 당대사 개선 효능 평가
송미영(Mi young Song) 한방비만학회 대한한방비만학회지 8 Pages
한방비만학회 대한한방비만학회지 2017, 제 17권 제 1호 4 29-36 (8 pages)
pandurata attenuates diet-induced obesity by activating AMP-activated protein kinase and regulating lipid metabolism. Int J Mol Sci. 2012 ; 13(1) : 994-1005. 23. Kahn BB, Flier JS. Obesity and insulin resistance. J Clin Invest. 2000 ; 106(4) : 473-81. 24. Landsberg L, Young JB, Leonard WR, Linsenmeier RA, Turek FW. Is obesity associated with lower body temperatures? Core temperature: a... -
Effects of exercise on obesity-induced mitochondrial dysfunction in skeletal muscle
Jun-WonHeo, Mi-HyunNo, Dong-HoPark, Ju-HeeKang, DaeYunSeo, JinHan, P.DarrellNeufer, Hyo-BumKwak 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.6 1 567-577 (11 pages)
in imbalance of mitochondrial fusion and fission and elevation of fission proteins. However, exercise training allows mitochondria to maintain the balance between fusion and fission by up-regulating fusion pro- teins and down-regulating fission proteins. ↓, decrease; ↑, increase; =, no change. ..PAGE:5 Exercise and mitochondria with obesity Korean J Physiol Pharmacol 2017;21(6):567-577... Obesity is known to induce inhibition of glucose uptake, reduction of lipid metabolism, and progressive loss of skeletal muscle function, which are all associated with mitochondrial dysfunction in skeletal muscle. Mitochondria are dynamic organelles that regulate cellular metabolism and bioenergetics, including ATP production via oxidative phosphorylation. Due to these critical roles of mitochondria, mitochondrial dysfunction results in various diseases such as obesity and type 2 diabetes.... -
Analysis of the Baroreceptor and Vestibular Receptor Inputs in the Rostral Ventrolateral Medulla following Hypotension in Conscious Rats
YanLan, Huan-JunLu, XianJiang, Li-WeiLi, Yan-ZhaoYang, Guang-ShiJin, JooYoungPark, MinSunKim, ByungRimPark, Yuan-ZheJin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.2 11 159-165 (7 pages)
canals, and project to the NTS, CVLM and RVLM [6-9]. The NTS receives primary inputs from car- diovascular, gastrointestinal, and pulmonary afferents and key components of the central pathway regulating the sym- pathetic vasomotor activity [10]. In addition, the NTS in- tegrates afferent signals from baroreceptors and vestibular receptors to control blood pressure [11]. The RVLM has direct... Input signals originating from baroreceptors and vestibular receptors are integrated in the rostral ventrolateral medulla (RVLM) to maintain blood pressure during postural movement. The contribution of baroreceptors and vestibular receptors in the maintenance of blood pressure following hypotension were quantitatively analyzed by measuring phosphorylated extracellular regulated protein kinase (pERK) expression and glutamate release in the RVLM. The expression of pERK and glutamate release in the... -
The Effect of Ghrelin on Ca2+ Concentration in Thyroid FRTL-5 Cells
ByungJooKim, YoungJooPark, DoJoonPark, InsukSo, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.4 4 195-200 (6 pages)
regulating thyroid hormone synthesis (Raspe et al, 1991). The activity of a calcium/NADPH-dependent thyroid peroxidase in the plas- ma membrane is considered to be the rate-limiting step in the iodination of tyrosine gr oups and the production of thyroid hormones. Therefore, agonists which increase [Ca 2+ ]i potently activate this system. Growth hormone secretagogues (GHSs) are synthetic pep-... Ghrelin is a newly discovered peptide, which is released from the stomach and neurons in the hypothalamic arcuate nucleus (ARC), and potently stimulates growth hormone release and food intake. In the present study, we investigated the effect of ghrelin on [Ca2]i in thyroid FRTL-5 cells. Ghrelin (5 nM) increased [Ca2]i and TSH (1 unit/l) had an additive effect on [Ca2]i when extracellular normal solution was 1.1mM Ca2 containing Coon's modified Ham's F12 medium. When... -
해마추상체 신경세포에서 칼슘에 의한 신경섬유 성장억제에 대한 칼파인 억제제의 영향
송동근(Dong-Keun Song), Stanley B. Kater, Donald L. Mykles 대한약리학회 대한약리학잡지 10 Pages
대한약리학회 대한약리학잡지 1993, 제 29권 제 2호 1 165-174 (10 pages)
Ca'+ before any effect of calpain inhibitor is observed. It is possible that culture conditions reduced the calpain activity in the hippocampal neurons, either by down-regulat- ing calpain or up-regulating calpastatin. In PC12 cells, for example, nerve growth factor-induced neuritogenesis is correlated with a decrease in calpain activity caused by increased levels of calpastatin (Oshima et... 칼슘이온은 신경섬유 성장의 중요한 조절인자이나 그 정확한 작용기전은 불명확하다. 세포골격 단백은 in vivo 및 in vitro에서 칼슘의존성 단백분해효소(칼파인)에 의해 신속히 분해되므로, 칼슘이온에 의한 신경섬유의 퇴행에 있어서 칼파인의 관련성을 추구하기위하여, 배양된 해마신경세포에서 칼슘이온 ionophore인 A23187에 의한 신경섬유의 성장억제가 칼파인의 억제제인 EST 및 MDL 28170에 의해 차단되는지를 조사하였다. A23187은 100nM의 농도에서 축삭에는 영향이 없이 수상돌기의 퇴행을 유발하였으나, 300 nM의 농도에서는... -
Special Education Policy in Nepal: A Critical Review from Policy Theory
Jung, Dae-Young, Rabindra Shiwakoti 부산대학교 교육발전연구소 교육혁신연구 22 Pages
부산대학교 교육발전연구소 교육혁신연구 2017, 제 27권 제 4호 11 219-240 (22 pages)
..PAGE:13 Special Education Policy in Nepal: A Critical Review from Policy Theory - 231 - 3. Structural Dimension This dimension emphasizes the structure of the institutions and plays vital role in regulating system and policy process. These structures are primarily the government organizations and institutions; and these structures help in promulgating and supporting policies in education. The... Purpose: Education policy is considered as a core document developed to ensure the educational rights of all children including the children with disabilities. By considering the fact, every nation design its educational policy to ensure access to basic education for all school-age children. Nepal Government has also been formulating different educational policies to ascertain educational rights of every child including the children with disabilities. Method: However, a group of children are... -
페룰 가공용 초정밀 무심 연삭기의 열 특성 해석
김석일, 조재완, Kim. Seo-Kil, Cho. Jae-Wan 한국정밀공학회 한국정밀공학회지 8 Pages
한국정밀공학회 한국정밀공학회지 2006, Vol.23 No.1 193-200 (8 pages)
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콘크리트 층진 베드를 적용한 초정밀 무심 연삭기의 구조 해석
김석일, 조재완, Kim. Seok Il, Cho. Jae Wan 한국정밀공학회 한국정밀공학회지 8 Pages
한국정밀공학회 한국정밀공학회지 2005, Vol.22 No.2 172-179 (8 pages)
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Thermal Characteristic Analysis of a High-Precision Centerless Grinding Machine for Machining Ferrules
Kim. Seok-Il, Cho. Jae-Wan 한국정밀공학회 International journal of precision engineering and manufacturing 6 Pages
한국정밀공학회 International journal of precision engineering and manufacturing 2007, Vol.8 No.1 32-37 (6 pages)
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Structural Characteristic Analysis of a High-precision Centerless Grinding Machine with a Concrete-filled Bed
Kim. Seok-Il, Cho. Jae-Wan 한국정밀공학회 International journal of precision engineering and manufacturing 6 Pages
한국정밀공학회 International journal of precision engineering and manufacturing 2006, Vol.7 No.4 34-39 (6 pages)