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Genetic Polymorphisms of Cytochrome P450 2C19 in Functional Dyspeptic Patients Treated with Cimetidine
MinheeKim, EunheeKong 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.5 8 339-342 (4 pages)
Korea), which is a simple, in- novative dual priming oligonucleotide (DPO) primer-based multiplex polymerase chain reaction system which has high specificity and sensitivity for detecting two single nucleo- tide polymorphisms: the CYP2C19*2 and CYP2C19*3 al- leles [6]. The allele specific DPO primers have an SNP in the middle of the 30-segment which maximizes disturbance of the 30-segment... with cimetidine in Korea. One hundred subjects with functional dyspepsia participated in this study from March 1, 2010 to June 30, 2011. They were tested by upper gastrointestinal endoscopy and treated for their dyspepsia with cimetidine. The single nucleotide polymorphisms (SNPs) of CYP2C19 were genotyped using the Seeplex CYP2C19 ACE Genotyping system. There were no significant differences in the demographic, clinical, or laboratory findings among the CYP2C19 subgroups which are wild type... -
Assessment of Relationship between Fyn-related Kinase Gene Polymorphisms and Overweight/Obesity in Korean Population
MiYoungJung, BumShikKim, YounJungKim, InSongKoh, Joo-HoChung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.2 8 83-86 (4 pages)
the genetic association between FRK polymorphisms and the risk of obesity in Korean population, single nucleotide polymorphisms (SNPs) in the FRK gene region were selected and analyzed. The body mass index (BMI) was calculated, and biochemical data (systolic blood pressure, diastolic blood pressure, hemoglobin A1C, triglyceride, total cholesterol, high density lipoprotein, and low density... To investigate the genetic association between FRK polymorphisms and the risk of obesity in Korean population, single nucleotide polymorphisms (SNPs) in the FRK gene region were selected and analyzed. The body mass index (BMI) was calculated, and biochemical data (systolic blood pressure, diastolic blood pressure, hemoglobin A1C, triglyceride, total cholesterol, high density lipoprotein, and low density lipoprotein) of blood sample from each subject were also measured. One hundred fifty five... -
Surveillanceof Chronic Wasting Disease in Korean Water Deer in South Korea
In Soon Roh, Hyun Joo Sohn, Hyun Jeong Kim, Tae Young Suh, Hyo Jin Kim, In Soo Cho, Jong Tak Kim, Jae Hwa Seo, Mun Seok Hur, Jip Seol Jeo 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 172 425-426 (2 pages)
exon of the PRNP gene. Four Polymorphisms in Korean water deer were G96D (0.1%), N100S (25.2%), D170G(0.8%), A187V (100%) when compared to the reference gene (GenBank, DQ358969.1). The PrP amino acid sequence of the Korean water deer showed 98.4~99.2%, 97.9~98.8% and 98.8~99.6% homology with those of American elk, mule deer and white-tailed de er, respectively. In addition, fourteen single... -
Application of biotechnological tools for coccidia vaccine development
Wongi Min, Rami A. Dalloul, Hyun S. Lillehoj 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2004, 제 5권 제 4호 1 279-288 (10 pages)
at the known position of the array. By comparing samples tested in well-controlled conditions, change of expression levels of individual genes can be detected. The DNA sequences immobilized on an array are usually produced by PCR from genes whose sequences are partially or completely known. This technique has been widely used to detect gene mutations and polymorphisms, gene expression profiling,... Coccidiosis is a ubiquitous intestinal protozoan infection of poultry seriously impairing the growth and feed utilization of infected animals. Conventional disease control strategies have relied on prophylactic medication. Due to the continual emergence of drug resistant parasites in the field and increasing incidence of broiler condemnations due to coccidia, novel approaches are urgently needed to reduce economic losses. Understanding the basic biology of host-parasite interactions and... -
정신분열병의 인지적 표지자와 Catechol-O-Methyltransferase Val158Met 유전자 다형성의 연합연구
박해정, 박동연, 조은영, 김나라, 전현옥, 이유상, 이동수, 홍경수 대한신경정신의학회 신경정신의학 8 Pages
대한신경정신의학회 신경정신의학 2008, 제 47권 제 2호 3 126-133 (8 pages)
EJ, Jeong SH, Yoon SC, Maeng SJ, Yoon KS, Chung IW, et al. Genetic association between single nucleotide polymorphism on COMT gene and schizophrenia in Korean population. Korean J Psy- chopharmacol 2003;14:172-180. 20) Kim MS, Chee IS, Lee SW, Shin SC, Lee YH. Catechol-O-methyl- transferase genepolymorphism (valine/methionine) associated neither with schizophrenia nor with bipolar disorder in... -
주의력결핍과잉행동장애에서 Alpha-2A-Adrenergic 수용체 유전자와 Methylphenidate 반응과의 연관성에 대한 연구
박진우, 김재원, 조수철, 김붕년, 신민섭, 홍순범, 박은진, 김효진, 박민현 대한신경정신의학회 신경정신의학 6 Pages
대한신경정신의학회 신경정신의학 2011, 제 50권 제 5호 8 386-391 (6 pages)
다형성 (single nucleotide polymorphism, 이하 SNP)과 DraI으로 알려진 3’ untranslated region의 C to T SNP가 ADHD와 관 련하여 연구된 두가지 주요 다형성(polymorphism)이다. 15,16) 본 연구자들의 이전 연구 17)에서는 한국인 ADHD의 원인에 있어 ADRA2A MspI 및 DraI 다형성이 관여한다는 증거를 제공했으며, 추가로 response time variability의 증가와 같은 ADHD의 신경심리 내적표현형(neuropsychological endo-... -
Oomycetes RXLR Effectors Function as Both Activator and Suppressor of Plant Immunity
한국식물병리학회 The Plant Pathology Journal 7 Pages
한국식물병리학회 The Plant Pathology Journal 2010, 26권 3호 1 209-215 (7 pages)
320-326. Qutob, D., Tedman-Jones, J., Dong, S., Kuflu, K., Pham, H., Wang, Y., Dou, D., Kale, S. D., Arredondo, F. D., Tyler, B. M. and Gijzen, M. (2009). Copy number variation and transcrip- tional polymorphisms of Phytophthora sojae RXLR effector genes Avr1a and Avr3a. PLoS One 4:e5056. Rehmany, A. P., Gordon, A., Rose, L. E., Allen, R. L., Armstrong, ..PAGE:7 Function of Oomycetes RXLR Effecto... Plant pathogenic oomycetes, such as Phytophthora spp., are the causal agent of the most devastating plant diseases. During infection, these pathogens accomplish parasitic colonization of plants by modulating host defenses through an array of disease effector proteins. These effectors are classified in two classes based on their target sites in the host plant. Apoplastic effectors are secreted into the plant extracellular space, and cytoplasmic effectors are translocated inside the plant cell,... -
Genetic Mapping of a Resistance Locus to Phytophthora sojae in the Korean Soybean Cultivar Daewon
Ik-Hyun Jang, In Jeong Kang, Ji-Min Kim, Sung-Taeg Kang, Young Eun Jang, Sungwoo Lee 한국식물병리학회 The Plant Pathology Journal 9 Pages
한국식물병리학회 The Plant Pathology Journal 2020, 36권 6호 6 591-599 (9 pages)
(R) if <20% died, susceptible (S) if >80% died, or intermediate (I) if 20 to 80% died. This experiment was replicated three times. ..PAGE:3 Rps in Daewon 593 DNA extraction and single nucleotide polymorphism (SNP) genotyping. Genomic DNA of parents and RILs was extracted using cetyl trimethyl ammonium bromide as described by Doyle and Doyle (1987). Samples were genotyped with Axiom 180 K... cross of Daepung × Daewon. Singlemarker analysis identified 20 single nucleotide polymorphisms associated with resistance to the P. sojae isolate 2457, which explained ~67% of phenotypic variance. Daewon contributed a resistance allele for the locus. This region is a well-known location for Rps1 and Rps7. The present study is the first, however, to identify an Rps gene locus from a major soybean variety cultivated in South Korea. Linkage analysis also identified a 573 kb region on chromosome 3... -
An update of preimplantation genetic diagnosis in gene diseases, chromosomal translocation, and aneuploidy screening
Chang. Li-Jung, Chen. Shee-Uan, Tsai. Yi-Yi, Hung. Chia-Cheng, Fang. Mei-Ya, Su. Yi-Ning, Yang. Yu-Shih 대한생식의학회 Clinical and experimental reproductive medicine 9 Pages
대한생식의학회 Clinical and experimental reproductive medicine 2011, Vol.38 No.3 126-134 (9 pages)