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간행물
- JOURNAL OF VETERINARY SCIENCE(8)
- THE KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY(5)
- HONAM MATHEMATICAL JOURNAL(3)
- 신경정신의학(3)
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- JOURNAL OF THE KOREAN MATHEMATICAL SOCIETY(1)
- STRUCTURAL ENGINEERING AND MECHANICS : AN INTERNATIONAL JOURNAL(1)
- THE KOREAN JOURNAL OF COMPUTATIONAL & APPLIED MATHEMATICS, 한국전산응용수학술지 SERIES A(1)
- 대한기계학회론문집. TRANSACTIONS OF THE KOREAN SOCIETY OF MECHANICAL ENGINEERS. A. A(1)
- 대한조선학회 논문집(1)
- 임상약리학회지= THE JOURNAL OF KOREAN SOCIETY FOR CLINICAL PHARMACOLOGY AND THERAPEUTICS(1)
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- 정보처리학회논문지. THE KIPS TRANSACTIONS. PART A. PART A(1)
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BOUNDS OF ZERO MEAN GAUSSIAN WITH COVARIANCE FOR AVERAGE ERROR OF TRAPEZOIDAL RULE
Hong. Bum-Il, Choi. Sung-Hee, Hahm. Nahm-Woo 한국전산응용수학회 The Korean journal of computational & applied mathematics, 한국전산응용수학술지 Series A 12 Pages
한국전산응용수학회 The Korean journal of computational & applied mathematics, 한국전산응용수학술지 Series A 2001, Vol.8 No.1 231-242 (12 pages)
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Effect of chronic lead intoxication on the distribution and elimination of amoxicillin in goats
Ahmed M. Soliman, Ehab A. Abu-Basha, Salah A. H. Youssef, Aziza M. Amer, Patricia A. Murphy, Catherine C. Hauck, Ronette Gehring 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2013, 제 14권 제 4호 4 395-403 (9 pages)
as previously described [11] with commercially available software (WinNonlin software version 5.2; Pharsight Corporation, USA). The AUC was calculated using the trapezoidal rule with extrapolation to infinity. C max and tmax were determined by inspecting the individual drug serum concentration-time profiles. The slope of the terminal phase of the time- concentration curve was calculated by... A study of amoxicillin pharmacokinetics was conducted in healthy goats and goats with chronic lead intoxication. The intoxicated goats had increased serum concentrations of liver enzymes (alanine aminotransferase and γ-glutamyl transferase), blood urea nitrogen, and reactivated δ-aminolevulinic acid dehydratase compared to the controls. Following intravenous amoxicillin (10 mg/kg bw) in control and lead-intoxicated goats, elimination half-lives were 4.14 and 1.26 h, respectively. The volumes... -
Quantitation of meloxicam in the plasma of koalas (Phascolarctos cinereus) by improved high performance liquid chromatography
Benjamin Kimble, Kong Ming Li, Merran Govendir* 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2013, 제 14권 제 1호 2 7-14 (8 pages)
a linear trapezoidal rule, terminal half life (t 1/2), volume of distribution (Vdarea), and clearance (CLarea). The formulae used were: t1/2 = 0.693/ (kel) where kel is the elimination rate constant, CLarea = dose/AUC0-∞, and Vdarea = dose/AUC0-∞*(kel). Results Chromatographic separation Based on the UV spectra, the optimal wavelength was set at 355 nm for quantitative analysis of MEL.... An improved method to determine meloxicam (MEL) concentrations in koala plasma using reversed phase high performance liquid chromatography equipped with a photo diode array detector was developed and validated. A plasma sample clean-up step was carried out with hydrophilic- lipophilic copolymer solid phase extraction cartridges. MEL was separated from an endogenous interference using an isocratic mobile phase [acetonitrile and 50 mM potassium phosphate buffer (pH 2.15), 45:55 (v:v)] on a... -
Disposition kinetics and urinary excretion of ciprofloxacin in goats following single intravenous administration
R. Raina, S. Prawez*, D.J. Dimitrova, N.K. Pankaj, P.K. Verma 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 3호 3 241-246 (6 pages)
pharmacokinetic analysis [11,40]. The non-compartment model was used to determine the area under concentration-time curve (AUC), and area under the first moment curve (AUMC), using the linear trapezoidal rule with extrapolation to time infinity. Mean residence time (MRT) and systemic clearance (Cl B) were calculated as MRT = AUMC/AUC and ClB = Dose/AUC, respectively. The apparent volumes of... We evaluated the pharmacokinetics of ciprofloxacin in serum (n = 6) and urine (n = 4) in goats following a single intravenous administration of 4 mg/kg body weight. The serum concentration-time curves of ciprofloxacin were best fitted by a two-compartment open model. The drug was detected in goat serum up to 12 h. The elimination rate constant (b) and elimination half-life (t1/2b) were 0.446 ± 0.04 h and 1.630 ± 0.17 h, respectively. The apparent volume of distribution at steady state...


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