자료유형
발행기관
- 대한생리학회-대한약리학회(10)
- 대한수의학회(8)
- 한국식물병리학회(5)
- 공주교육대학교 초등교육연구원(1)
- 대한생리학회(1)
- 대한신경계작업치료학회(1)
- 대한약리학회(1)
- 대한전자공학회(1)
- 인문사회과학기술융합학회(1)
- 한국습지학회(1)
간행물
- THE KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY(10)
- JOURNAL OF VETERINARY SCIENCE(6)
- THE PLANT PATHOLOGY JOURNAL (5)
- KOREAN JOURNAL OF VETERINARY RESEARCH(구 대한수의학회지)(2)
- 교육논총(1)
- 대한생리학회지(1)
- 대한약리학잡지(1)
- 예술인문사회융합멀티미디어논문지(1)
- 재활치료과학(1)
- 전자공학회논문지. JOURNAL OF THE INSTITUTE OF ELECTRONICS ENGINEERS OF KOREA. TC, 통신(1)
- 한국습지학회지(1)
전체 선택해제
총 30건 검색
본문검색 결과만 보기
-
Pharmacokinetics of tilmicosin in healthy pigs and in pigs experimentally infected with Haemophilus parasuis
Ling Zhang, Li Zhao, Yonghong Liu, Junfeng Liu, Xianqiang Li 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 4호 2 431-437 (7 pages)
polyvinylidene difluoride filter (Chucheng, China). The plasma TIL concentration was linear over the range of 0.02 g/mL with a correlation coefficient of 0.999. The limit of quantification (LOQ) was 0.05 g/mL and the intra-day variation for the three different plasma concentrations (0.02, 0.5 and 5 g/mL) were 2.37%, 2.89%, and 3.45%, respectively, while inter-day variation were 1.62%, 2.11%,... A comparative in vivo pharmacokinetic (PK) study of tilmicosin (TIL) was conducted in 6 crossbred healthy pigs and 6 crossbred pigs infected with Haemophilus (H.) parasuis following oral administration of a single 40 mg/kg dose. The infected model was established by intranasal inoculation and confirmed by clinical signs, blood biochemistry, and microscopic examinations. Plasma TIL concentrations were determined by a validated high-performance liquid chromatography method with ultraviolet... -
Preparation and evaluation of enrofloxacin microspheres and tissue distribution in rats
Fan Yang, Jijun Kang, Fang Yang, Zhensheng Zhao, Tao Kong, Zhenling Zeng 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 2호 4 157-164 (8 pages)
0.22-m syringe filter into a sample vial. Extraction of the drugs from tissues was performed using a previously published method [27] with minor modifications. Briefly, 0.5 g of homogenized tissue was placed in a centrifuge tube and mixed with 0.2 M phosphate buffer (0.5 mL). The extraction protocol was performed twice with 3 mL of DCM. For each round of extraction, the solution was vortexed... New enrofloxacin microspheres were formulated, and their physical properties, lung-targeting ability, and tissue distribution in rats were examined. The microspheres had a regular and round shape. The mean diameter was 10.06 μm, and the diameter of 89.93% of all microspheres ranged from 7.0 μm to 30.0 μm. Tissue distribution of the microspheres was evaluated along with a conventional enrofloxacin preparation after a single intravenous injection (7.5 mg of enrofloxacin/kg bw). The results... -
Effect of chronic lead intoxication on the distribution and elimination of amoxicillin in goats
Ahmed M. Soliman, Ehab A. Abu-Basha, Salah A. H. Youssef, Aziza M. Amer, Patricia A. Murphy, Catherine C. Hauck, Ronette Gehring 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2013, 제 14권 제 4호 4 395-403 (9 pages)
amoxicillin, bioavailability, disposition, lead intoxication, pharmacokinetics Introduction Lead is a high-risk environmental pollutant and extensively used by industry. This metal is therefore widely distributed in the environment. Routes of lead exposure include air, water, soil, food, and consumer products. One of the largest sources is chipping lead-based paint that exists in many old... A study of amoxicillin pharmacokinetics was conducted in healthy goats and goats with chronic lead intoxication. The intoxicated goats had increased serum concentrations of liver enzymes (alanine aminotransferase and γ-glutamyl transferase), blood urea nitrogen, and reactivated δ-aminolevulinic acid dehydratase compared to the controls. Following intravenous amoxicillin (10 mg/kg bw) in control and lead-intoxicated goats, elimination half-lives were 4.14 and 1.26 h, respectively. The volumes... -
Development of a monoclonal antibody against deoxynivalenol for magnetic nanoparticle-based extraction and an enzyme-linked immunosorbent assay
Hyuk-Mi Lee, Sung-Ok Song, Sang-Ho Cha, Sung-Bok Wee, Karyn Bischoff, Sung-Won Park, Seong-Wan Son, Hwan-Goo Kang*, Myung-Haing 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2013, 제 14권 제 2호 5 143-150 (8 pages)
was spiked with different concentrations of DON (0, 250, 500 and 1,000 ng/g) and extracted with 100 mL water for 3 min by vigorous agitation. The extracts were filtered through Whatman No. 1 filter paper (GE Heathcare, UK). The concentration of DON in the extracted samples was measured using both ELISA systems developed in the current study. Conjugation of mAbs and MNPs A total 3 mg of an... Monoclonal antibody (mAb, NVRQS-DON) against deoxynivalenol (DON) was prepared. DON-Ag coated enzyme linked immunosorbent assay (ELISA) and DON-Ab coated ELISA were prepared by coating the DON-BSA and DON mAb. Quantitative DON calculation ranged from 50 to 4,000 ng/mL for DON-Ab coated ELISA and from 25 to 500 ng/mL for DON-Ag coated ELISA. 50% of inhibitory concentration values of DON, HT-2, 15-acetyl-DON, and nivalenol were 23.44, 22,545, 5,518 and 5,976 ng/mL based on the DON-Ab coated ELISA.... -
Efficacy of nano-hydroxyapatite prepared by an aqueous solution combustion technique in healing bone defects of goat
Samit Kumar Nandi, Biswanath Kundu*, Samir Kumar Ghosh, Dipak Kumar De, Debabrata Basu 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 2호 9 183-192 (10 pages)
materials, polymers, ceramics, and composites of the above materials have been recommended to fill and reconstruct bone defects, but none have been shown to be ideal. However, metals are being widely used for major load-bearing orthopedic applications [28]. The materials have many limitations, though, due to unfavour- able corrosion properties, wear, encapsulation by dense fibrous tissues to... The present study was undertaken to evaluate porous hydroxyapatite (HAp), the powder of which was prepared by a novel aqueous solution combustion technique, as a bone substitute in healing bone defects in vivo, as assessed by radiologic and histopathologic methods, oxytetracycline labeling, and angiogenic features in Bengal goat. Bone defects were created in the diaphysis of the radius and either not filled (group I) or filled with a HAp strut (group II). The radiologic study in group II showed... -
Comparative study of PM2.5 - and PM10 - induced oxidative stress in rat lung epithelial cells
Jin-Hyuk Choi, Jun-Sung Kim, Young-Chul Kim, Yoon-Shin Kim, Nam-Hyun Chung and Myung-Haing Cho 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2004, 제 5권 제 1호 3 11-18 (8 pages)
coarse mode (<10m). Two fractions of particles were collected onto two separate filters: one filter containing PM10 and the other filter containing PM2.5. Preparation and extraction of filters Teflon filters were baked for 2 h at 100 oC and transferred into 50 ml conical tube with the particles facing 0.1× PBS. Extraction of the PMs took place in an ultrasonic bath three times for 20 minutes. The... Accurate estimation of the exposure-response relationship between ambient urban particulate matters (PM) and public health is important for regulatory perspective of ambient urban particulate matters (PM). Ambient PM contains various transition metals and organic compounds. PM10 (aerodynamic diameter less than 10 μm) is known to induce diverse diseases such as chronic cough, bronchitis, chest illness, etc. However, recent evaluation of PM2.5 (aerodynamic diameter less than 2.5 μm) against... -
Evaluation of bioequivalence of two enrofloxacin formulations after intramuscular administration in goats
Mohamed Hafez Aboubakr 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 6 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2013, 제 53권 제 2호 3 77-82 (6 pages)
It is widely used in veterinary medicine in cattle, pigs, poultry, fish, dogs and cats in the treatment of diseases caused by aerobic Gram-negative, Gram-positive bacteria and such pathogens as Mycoplasma, Chlamydia and Rickettsia [7]. It is mainly indicated for gastrointestinal, urogenital, skin and respiratory tract infections in various domestic animal species [29, 2]. It is metabolized to... -
The bifunctional effect of propofol on thromboxane agonist (U46619)-induced vasoconstriction in isolated human pulmonary artery
NingHao, ZhaojunWang, SujuanKuang, GuangyanZhang, ChunyuDeng, JueMa, JianxiuCui 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.6 3 591-598 (8 pages)
by non-linear regression curve fitting (Graphpad Prism software, version 5.0). Effect curves were analyzed by non- linear curve fitting using Sigmaplot version 10.0 (Systat Software, Chicago, IL, USA). One-way ANOVA followed by the LSD test was used for statistical analysis when more than two groups were compared. Individual concentration response curves were compared by two- way analysis of... Propofol is known to cause vasorelaxation of several systemic vascular beds. However, its effect on the pulmonary vasculature remains controversial. In the present study, we investigated the effects of propofol on human pulmonary arteries obtained from patients who had undergone surgery. Arterial rings were mounted in a Multi-Myograph system for measurement of isometric forces. U46619 was used to induce sustained contraction of the intrapulmonary arteries, and propofol was then applied (in... -
A Novel Nicotinamide Adenine Dinucleotide Correction Method for Mitochondrial Ca2+ Measurement with FURA-2-FF in Single Permeabilized Ventricular Myocytes of Rat
JeongHoonLee, JeongMiHa, ChaeHunLeem 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.4 10 373-382 (10 pages)
that are widely used for the quantitative measurement of [Ca 2+]. However, the dye usage is intrinsically limited, as the dyes require ultraviolet (UV) excitation, which can also generate great interference, mainly from nicotinamide adenine dinucleotide (NADH) autofluorescence. Specifically, this limitation causes serious problems for the quantitative measurement of mitochondrial [Ca 2+], as... Fura-2 analogs are ratiometric fluoroprobes that are widely used for the quantitative measurement of [Ca2+]. However, the dye usage is intrinsically limited, as the dyes require ultraviolet (UV) excitation, which can also generate great interference, mainly from nicotinamide adenine dinucleotide (NADH) autofluorescence. Specifically, this limitation causes serious problems for the quantitative measurement of mitochondrial [Ca2+], as no available ratiometric dyes are excited in the visible range.... -
The Effect of Methanol on the Structural Parameters of Neuronal Membrane Lipid Bilayers
Hyung-JinJoo, Shin-HoAhn, Hang-RaeLee, Sung-WooJung, Chang-WonChoi, Min-SeokKim, Moon-KyoungBae, In-KyoChung, Soo-KyoungBae, Hye-OckJang, 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.4 5 255-264 (10 pages)
almost linear ly related to the number of carbon atoms between it and carboxyl group) [16-19]. The fluorophores of anthroyloxy derivatives can also be used to differentiate whether the bilayer has a fluidity gradient across it, as the anthroyloxy group can be positioned at dif- ferent positions of the stearic acid moiety [18-21]. These probes have been suggested to measure primarily the dy-... The structures of the intact synaptosomal plasma membrane vesicles (SPMVs) isolated from bovine cerebral cortexs, and the outer and the inner monolayer separately, were evaluated with 1,6-diphenyl- 1,3,5-hexatriene (DPH) and 1,3-di(1-pyrenyl)propane (Py-3-Py) as fluorescent reporters and trinitrophenyl groups as quenching agents. The methanol increased bulk rotational and lateral mobilities of SPMVs lipid bilayers. The methanol increased the rotational and lateral mobilities of the outer...