자료유형
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Optimum Conditions for the Formation of Acetoin as a Precursor of Tetramethylpyrazine during the Citrate Fermentation by Lactococcus lactis subsp. lactis biovar. diacetilactis FC1
Kim. Kyoung-Heon, Lee. Hyong-Joo 한국미생물생명공학회 Journal of microbiology and biotechnology 5 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 1991, Vol.1 No.3 202-206 (5 pages)
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Inhibition of β-amyloid1-40 Peptide Aggregation and Neurotoxicity by Citrate
YongHoonPark, Young-JinKim, IlHongSon, HyunDukYang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.4 2 273-279 (7 pages)
β1-40 aggregates. Accordingly, our findings suggest that citrate administration should be viewed as a novel neuroprotective strategy for AD. Key Words: Citrate, Alzheimer’s disease, β-amyloid, Aggregation, Apoptosis INTRODUCTION The accumulation of β-amyloid (Aβ) peptides in senile plaque represents a major pathological change in the AD brain. Aβ is generated by the sequential proteolytic... from 84.6 to 93.8% as compared with the AՂ1-40 aggregates alone treated cells (65.3%). Furthermore, Hoechst 33342 staining showed that citrate (1.0 mM) suppressed AՂ1-40 aggregates-induced apoptosis in the cells. This study suggests that citrate can inhibit AՂ1-40 aggregation and protect neurons from the apoptotic effects of AՂ1-40 aggregates. Accordingly, our findings suggest that citrate administration should be viewed as a novel neuroprotective strategy for AD. -
Immunohistochemical evaluation of the goat forestomach during prenatal development
Angela Garcia, Javier Masot, Antonio Franco, Antonio Gazquez, Eloy Redondo, * 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 1호 4 35-43 (9 pages)
are thought to arise from the same precursor cell as a different type of epithelial cell [32]. These neuroendocrine cells originating in the embryonic neural crest migrate to the gastrointestinal epithelium during the course of prenatal development [24]. GFAP-positive glial cells were detected at 68 days (45% gestation) in the rumen, and at 64 days (43% gestation) in reticulum and omasum.... Here we report the detection and distribution of synaptophysin (SPY), non-neuronal enolase (NNE), glial fibrillary acidic protein (GFAP), vimentin (VIM), neuropeptide Y (NPY), and vasoactive intestinal peptide (VIP) expression in the goat forestomach during prenatal development. A total of 140 embryos and fetuses were examined to evaluate protein expression from the first stage of prenatal life until birth. In all cases, SPY immunoreactivity was detected at 53 days gestation in the lamina... -
Immunohistochemical Localization of Bcl-2 in the Spinal Cords of Rats with Experimental Autoimmune Encephalomyelitis
Chang-Jong Moon, Yong-Duk Lee and Tae-Kyun Shin 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 4호 5 279-283 (5 pages)
as a site for precursor T cell proliferation and effector T cell selection in experimental autoimmune encephalomyelitis. J. Neuroimmunol. 1995,56, 171-178. 17. Waggoner, S.E., Baunoch, D.A., Anderson, S.A., Leigh,F.,Zagaja,V.G.Bcl-2 protein expression associated with resistance to apoptosis in clear cell adenocarcinoma of the vagina and cervix expressing wild-type p53.Ann. Surg. Oncol. 1998, 5,... We examined the localization of the anti-apoptotic molecule Bcl-2 in the spinal cords of Lewis rats with experimental autoimmune encephalomyelitis (EAE). Western blot analysis showed that Bcl-2 was constitutively expressed in normal spinal cords, and weakly increased in response to complete Freund's adjuvant(CFA) immunization. In EAE, with infiltration of inflammatory cells into spinal cords, Bcl-2 declined during the peak stage and further decreased during the recovery stage.... -
Enhanced expression of constitutive and inducible forms of nitric oxide synthase in autoimmune encephalomyelitis
Seungjoon Kim, Changjong Moon, Myung Bok Wie, Hyungmin Kim, Naoyuki Tanuma, Yoh Matsumoto, Taekyun Shin 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2000, 제 1권 제 1호 2 11-17 (7 pages)
site for precursor T cell proliferation and effector and T cell selection in experimental autoimmune encephalomyelitis. J. Neuroimmunol. 1995, 56(2), 171-178. 43. Shin, T., Tanuma, N., Kim, S., Jin, J., Moon, C., Kim, K., Kohyama, K., Matsumoto, Y. and Hyun, B. An inhibitor of inducible nitric oxide synthase ameliorates experimental autoimmune myocarditis. J. Neuroimmunol. 1998, 92(1-2), 133-138.... To elucidate the role of nitric oxide synthase (NOS) in the pathogenesis of experimental autoimmune encephalomyelitis (EAE), we analyzed the expression of constitutive neuronal NOS (nNOS), endothelial NOS (eNOS), and inducible NOS (iNOS) in the spinal cords of rats with EAE. We further examined the structural interaction between apoptotic cells and spinal cord cells including neurons and astrocytes, which are potent cell types of nitric oxide (NO) production in the brain. Western blot analysis... -
Original Article : Virulence factors, antimicrobial resistance patterns, and genetic characteristics of hydrogen sulfide-producing Escherichia coli isolated from swine
Hyun Eui Park , Min Kyoung Shin , Hong Tae Park , Seung Won Shin , Myunghwan Jung , Young Bin Im , Han Sang Yoo 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 7 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2015, 제 55권 제 3호 7 191-197 (7 pages)
via a precursor molecule. Mol Microbiol 1992, 6, 1539-1546. 7. Darland G, Davis BR. Biochemical and serological characterization of hydrogen sulfide-positive variants of Escherichia coli. Appl Microbiol 1974, 27, 54-58. 8. Furrer B, Candrian U, Luthy J. Detection and identification of E. coli producing heat-labile enterotoxin type I by enzymatic amplification of a specific DNA fragment. Lett Appl... -
Original Article : Chemopreventive effects of garlic and mugwort mixture extract on Helicobacter pylori-associated mouse gastric carcinogenesis
So Young Youm , Tae Wang Kim , Sang Kyung Shin , Heon Sang Jeong , Jong Koo Kang , Tae Myoung Kim , Kil Ho Kim , Byeong 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 7 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2014, 제 54권 제 3호 7 171-177 (7 pages)
of gas- tric tumors, the gastric mucosae of non-neoplastic lesion were examined histologically to determine whether GME affected the development of precursor lesions of dysplasia (glandular atrophy, chronic inflammation and intestinal metaplasia). GME also significantly suppressed the histologic grades of those lesions in high dose groups determined by quantitative histo- pathological scoring (p <... -
Isolation and characterization of fowl adenovirus serotype 4 from chickens with hydropericardium syndrome in Korea
Hong Su Park , Il Soo Lim , Sang Kyu Kim , Toh Kyung Kim , Sang Geon Yeo 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 8 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2011, 제 51권 제 3호 5 209-216 (8 pages)
a peptide with 107 kDa as hexon protein. In these Indian strains, there also were polypeptide bands above 107 kDa, which were proposed as precursor polypeptides. On the other hands, Kumar and Chandra [13] reported a strain of Indian FAdV isolated from HPS had 12 peptide bands ranged 13.8~110 kDa, and they supposed a 110 kDa-peptide was hexon protein. In the present study, similarly, a peptide band... -
NecroX-5 protects mitochondrial oxidative phosphorylation capacity and preserves PGC1α expression levels during hypoxia/ reoxygenation injury
VuThiThu, HyoungKyuKim, LeThanhLong, BayalagmaaNyamaa, In-SungSong, ToThanhThuy, NguyenQuangHuy, JubertMarquez, SoonHaKim, NariKim, KyungS 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.2 9 201-211 (11 pages)
kDa 0.58 Clpp Putative ATP-dependent Clp protease proteolytic subunit, mitochondrial precursor IPI00373718 30 kDa 0.58 Nexn Nexilin IPI00209938 78 kDa 0.75 B. Up-regulated protein expression Identified Proteins Identified Proteins Accession Number MW Expression ratio (NecroX-5/HR) Atp5i ATP synthase subunit e, mitochondrial IPI00231978 8 kDa 1.46 Ak1 Adenylate kinase isoenzyme 1 IPI00210351 22... system. Proteomic analysis was performed using liquid chromatography-mass spectrometry (LC-MS) and non-labeling peptide count protein quantification. Real-time PCR, western blot, citrate synthases and mitochondrial complex activity assays were then performed to assess heart function. Treatment with NecroX-5 during hypoxia significantly preserved electron transport chain proteins involved in oxidative phosphorylation and metabolic functions. NecroX-5 also improved mitochondrial complex I, II, and... -
Epigallocatechin-3-Gallate (EGCG) Attenuates Traumatic Brain Injury by Inhibition of Edema Formation and Oxidative Stress
BoZhang, BingWang, ShuhuaCao, YongqiangWang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.6 3 491-497 (7 pages)
8. Rezai-Zadeh K, Shytle D, Sun N, Mori T, Hou H, Jeanniton D, Ehrhart J, Townsend K, Zeng J, Morgan D, Hardy J, Town T, Tan J. Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice. J Neurosci. 2005;25: 8807-8814. 9. Ahn HY, Kim CH, Ha TS. Epigallocatechin-3-gallate regulates Nadph oxidase... Traumatic brain injury (TBI) is a major cause of mortality and long-term disability, which can decrease quality of life. In spite of numerous studies suggesting that Epigallocatechin-3- gallate (EGCG) has been used as a therapeutic agent for a broad range of disorders, the effect of EGCG on TBI remains unknown. In this study, a weight drop model was established to evaluate the therapeutic potential of EGCG on TBI. Rats were administered with 100 mg/kg EGCG or PBS intraperitoneally. At different...