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전체 선택해제
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The Effects of A High-Fat Diet on Pro- and Macro-Glycogen Accumulation and Mobilization During Exercise in Different Muscle Fiber Types and Tissues in Rats
Lee. Jong-Sam, Eo. Su-Ju, Cho. In-Ho, Pyo. Jae-Hwan, Kim. Hyo-Sik, Lee. Jang-Kyu, Kwon. Young-Woo, Kim. Chang-Keun 한국영양학회 Nutritional sciences 8 Pages
한국영양학회 Nutritional sciences 2005, Vol.8 No.3 181-188 (8 pages)
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Mechanical and electrical properties of cement paste incorporated with pitch-based carbon fiber
Inkyu Rhee, Jin Hee Kim, Sang Hee Park, Sungho Lee, Bong Ryeul Ryu, Yoong Ahm Kim 한국탄소학회 Carbon Letters 8 Pages
한국탄소학회 Carbon Letters 2017, Vol.23 4 22-29 (8 pages)
a novel dispersion method have been reported, prob- lems remain for applying these nano-inclusions to the structure member of the macro-size, such as mortar and concrete in terms of strength, durability and electrical performance. In fact, car- bon fber is not a new material; it has been used commercially since 1963 [12]. Carbon fbers can be divided into pitch-based and PAN-based carbon fbers.... The compressive strength and electrical resistance of pitch-based carbon fiber (CF) in cementitious materials are explored to determine the feasibility of its use as a functional material in construction. The most widely used CFs are manufactured from polyacrylonitrile (PAN-based CF). Alternatively, short CFs are obtained in an economical way using pitch as a precursor in a melt-blown process (pitch-based CF), which is cheaper and more eco-friendly method because this pitch-based CF is basically... -
Tricyclic antidepressant amitriptyline inhibits 5-hydroxytryptamine 3 receptor currents in NCB-20 cells
Yong Soo Park, Seok Ho Myeong, In-Beom Kim, Ki-Wug Sung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.5 12 585-595 (11 pages)
in simulated data was consistent with our macro- scopic current data, which showed desensitization was accelerated by amitriptyline only in the co-application mode (Fig. 6). In the pre-application mode, receptor desensitization might be occurred not much because current rise slowly and did not decay to the end of 5-HT application, thus kd+ was not significantly changed (Table 1). Although a... Amitriptyline, a tricyclic antidepressant, is commonly used to treat depression and neuropathic pain, but its mechanism is still unclear. We tested the effect of amitriptyline on 5-hydroxytryptamine 3 (5-HT3) receptor currents and studied its blocking mechanism because the clinical applications of amitriptyline overlapped with 5-HT3 receptor therapeutic potentials. Using a whole-cell voltage clamp method, we recorded the currents of the 5-HT3 receptor when 5-HT was applied alone or co-applied... -
The Critical Roles of Zinc: Beyond Impact on Myocardial Signaling
SungRyulLee, SuJinNoh, JuliusRyanPronto, YuJeongJeong, HyoungKyuKim, InSungSong, ZhelongXu, HyogYoungKwon, SeChanKang, Eun-HwaSohn, KyungS 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.5 1 389-400 (12 pages)
macro Zn 2+ transporter to target tissues; thus, changes in the concentration of albumin or an increase of fatty acids, which interferes with Zn 2+ binding to albumin, impairs the control of blood Zn 2+ levels. The availability of intracellular Zn 2+ is governed by the action of MTs (MTs; binding or trapping of Zn 2+), zinc transporters (ZnTs; Zn 2+ efflux), Zn 2+ importers (ZIPs; Zn 2+ influx)... Zinc has been considered as a vital constituent of proteins, including enzymes. Mobile reactive zinc (Zn2+) is the key form of zinc involved in signal transductions, which are mainly driven by its binding to proteins or the release of zinc from proteins, possibly via a redox switch. There has been growing evidence of zinc’s critical role in cell signaling, due to its flexible coordination geometry and rapid shifts in protein conformation to perform biological reactions. The importance and... -
Matrix Metalloproteinase Inhibitors Attenuate Neuroinflammation Following Focal Cerebral Ischemia in Mice
CheolHongPark, TaeKyeongShin, HoYounLee, SoJungKim, WonSukLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.2 7 115-121 (7 pages)
A fiber optic bundle of a cold light source (KL 1500 LCD; Carl Zeiss, Gottingen, Germany) with a 4-mm aperture was centered using a micromanipulator at a lateral distance of 2 mm from the bregma. The ap erture of the cold light source was placed as close as possible to the skull to avoid scattering of light, which can cause variability. The skull was then irradiated for 15 min starting at 5... The aim of this study was to investigate whether matrix metalloproteinase (MMP) inhibitors attenuate neuroinflammation in an ischemic brain following photothrombotic cortical ischemia in mice. Male C57BL/6 mice were anesthetized, and Rose Bengal was systemically administered. Permanent focal ischemia was induced in the medial frontal and somatosensory cortices by irradiating the skull with cold white light. MMP inhibitors, such as doxycycline, minocycline, and batimastat, significantly reduced... -
Study on the Action by PAF on IL-1 Modulation in Alveolar Macrophages Involvement of Endogenous Arachidonate Metabolites and Intracellular Ca++ Mobilization
JiheeLee, Won-KiKim, Jong-SikHah 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.2 13 241-249 (9 pages)
AF on IL-l Modulation in Alveolar Macro phages: Involvement of Endogenous Arachidonate Metabolites and ++ Intracellular Ca" Mobilization 2 Jihee Lee， Won-Ki Kim"， and Jong-Sik Hah Department of 1Physiology and 2Pharmacology， College of Medicine， Ewha Womans University， Seoul 158 -056， Korea Platelet-activating factor(PAF) enhanced interleukin-l(IL-l) activity by the interaction with... Platelet-activating factor(PAF) enhanced interleukin-1(IL-1) activity by the interaction with a specific receptor in rat alveolar macrophages. In this study, we investigated the role of endogenous arachidonate metabolites and intracellular calcium mobilization in the PAF-induced IL-1 activity. Alveolar macrophages were preincubated with 5-lipoxygenase and cyclooxygenase inhibitors 30 min before the addition of PAF and lipopolysaccharide(LPS). After 24h culture, IL-1 activity was measured in the... -
정신분열병환자의 뇌량에 대한 신경병리적 고찰： 확산텐서영상(Diffusion Tensor Image)기법의 적용
이경진, 신용욱, 하태현, 이종민, 김인영, 김선일, 문원진, 정은철, 박해정, 오정은, 박지영, 강경훈, 권기원, 권준수 대한신경정신의학회 신경정신의학 7 Pages
대한신경정신의학회 신경정신의학 2005, 제 44권 제 4호 7 432-438 (7 pages)
고안되어진 영상기법이다. 특히 백질에서 축삭돌기가 신 경섬유의 경로(fiber track)를 따라 수직방향을 이루고 이 때 수초화된 백질 내부에 있는 물 분자들의 움직임 역시 축삭돌기의 방향을 따라 수직의 방향성을 형성하기 때문 에 물분자의 확산정도에 있어서 비등방성(anisotropy)이 생기게 된다. 백질 내부의 물분자는 정상적으로 수직의 방향성 즉 비등방성을 이루어야 하며 그렇지 못하고 감 소하는 경우 이는 백질의...