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Effects of Repeated Citalopram Treatments on Chronic Mild Stress- Induced Growth Associated Protein-43 mRNA Expression in Rat Hippocampus
Sang-HaPark, Song-hyenChoi, JiminLee, SeungwooKang, You-ChanShin, Hyun-JuKim, HyunJungKim, SeungKeonShin, Min-SooLee, Kyung-HoShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.3 5 117-124 (8 pages)
GAP-43 mRNA expression in CA3 region of the hippocampus, however, tianeptine pretreatment does not prevent chronic restraint stress-induced decrease in ..PAGE:2 118 SH Park, et al Table 1. Schedule of chronic mild stress Monday Tuesday Wednesday Thursday Friday Morning Restraint 1 h Restraint 1 h Access to restricted food (3 g) for 2 h 1 h exposure to empty bottle, restraint 1 h Restraint 1 h... chronic mild stress (CMS)-induced changes in GAP-43 mRNA expression in the hippocampus have not been explored before. To explore this question, male rats were exposed to acute immobilization stress or CMS. Also, citalopram was given prior to stress everyday during CMS procedures. Acute immobilization stress significantly increased GAP-43 mRNA expression in all subfields of the hippocampus, while CMS significantly decreased GAP-43 mRNA expression in the dentate granule cell layer (GCL). Repeated... -
Fluoxetine이 Schedule-Induced Polydipsia가 유발된 백서 뇌에서 Tyrosine Hydroxylase 발현에 미치는 영향
이기철, 이정호, 최영민, 정주호, 정홍경, 이용민, 김도형, 이대환 대한신경정신의학회 신경정신의학 8 Pages
대한신경정신의학회 신경정신의학 2001, 제 40권 제 2호 17 348-355 (8 pages)
Schedule-Induced Polydipsia 가 유발된 백서 뇌에서 Tyrosine Hydroxylase 발현에 미치는 영향 * 이기철 1)†·이정호 1)·최영민 1)·정주호 2) 정홍경 1)·이용민 3)·김도형 1)·이대환 1) Effects of Fluoxetine on Tyrosine Hydroxylase Expression in Schedule-Induced Polydipsia Rats* Gi-Chul Lee, M.D., 1)† Jung-Ho Lee, M.D., 1) Young-Min Choi, M.D., 1) Joo-Ho Chung, M.D., 2) Hong-Kyung Jung, M.D., 1)... 유발한다고 알려져 있다. 그러나 신경세포체에서 fluoxetine이 dopamine에 어떠한 영향을 주는지는 아직까지 확실치 않다. 저자들은 schedule-induced polydipsia를 유발시 킨 백서 뇌의 흑질, 복부피개영역, 미상핵에서 tyrosine hydroxylase(TH) 발현이 저하됨을 발견하였다. 이를 통해서 fluoxetine 만성투여가 백서 뇌에서 dopamine 기능에 미치는 영향을 알아 보고, 그 결과로서 fluoxetine이 백서 뇌의 dopamine 기능에 긍정적인지 혹은 부정적인지를 규명하고자 하였다. 방 법： 4주간의 schedule-induced polydipsia 과정을 거친... -
The effects computerized cognitive rehabilitation on cognitive function, depression, rehabilitative motivation in older adults with mild cognitive impairment : A pilot study
Moon Jong-Hoon 고령자치매작업치료학회 고령자·치매작업치료학회지 8 Pages
고령자치매작업치료학회 고령자·치매작업치료학회지 2019, 제 13권 제 2호 4 25-32 (8 pages)
to level 5. All sub- jects also received universal occupational therapy in ac- cordance with the rehabilitation schedule for four weeks. The occupational therapy included purposeful activities based on the patient’s desired activities in a clinical set- ting (Moon et al., 2018). After the interventions were completed, a post-assessment was performed (Figure 1). Figure 1. Diagram of this study... aims to investigate the effects of computerized cognitive rehabilitation on cognitive function, depression, and rehabilitative motivation in older adults with mild cognitive impairment (MCI). Methods : This pilot study follows a pre-post design and 15 older adults with MCI participated. The intervention comprised of 30-minute sessions 4 to 5 times a week for 4 weeks. The Lowenstein Occupational Therapy Cognitive Assessment-G (LOTCA-G), the short form Geriatric Depression Scale (SGDS-K), and a... -
The effects of low level laser radiation on bacterial growth
Wendy Chung, Jerrold S. Petrofsky, Michael Laymon, Jason Logoluso, Joon Park, Judy Lee, Ha-neul Lee 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2014, 제 3권 제 1호 4 20-26 (7 pages)
Irradiation schedule for bacteria exposure to laser light (unit: lux) IR Low red Low blue Low green Low UV High red High blue High green High UV Escherichia coli (×3 trials) 5,000 5,000 5,000 5,000 5,000 240,000 230,000 16,000 100,000 Pseudomonas aeruginosa (×3 trials) 5,000 5,000 5,000 5,000 5,000 240,000 230,000 16,000 100,000 Staphylococcus aureus (×3 trials) 5,000 5,000 5,000 5,000 5,000... Objective: The low level lasers currently in the market vary in wavelength, dosage, and frequency. These devices are used with much different clinical pathology. Most notably, some studies claim that wounds heal faster with low level laser therapy due to the fact that bacteria commonly found in wounds are killed by laser light. Systemic and meta-analysis studies found the difficulty of comparison of numerous research studies because of differences in the intensities and frequencies of low level... -
Evaluation of a fixed-dose combination of benazepril and pimobendan in dogs with congestive heart failure: a randomized non-inferiority clinical trial
Jonathan N. King, Atsushi Hirakawa, Junko Sonobe, Hiroshi Otaki, Nobuhiro Sakakibara, Wolfgang Seewald, Sophie Forster 대한수의학회 Journal of Veterinary Science 12 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 1호 15 117-128 (12 pages)
fixed-dose combination tablets of benazepril and pimobendan ..PAGE:2 118 Jonathan N. King et al. Journal of Veterinary Science Table 1. Study schedule Responsible Event/day (D) D0 D7 ± 1 D14 ± 2 D28 ± 2 D56 ± 3 At withdrawal Visit to clinic X X X X X X Investigator Case history and baseline X Inclusion/exclusion criteria X Owner’s consent X Physical examination,odyweightnd BCSX GCS X X X X X... A fixed-dose combination tablet of benazepril and pimobendan (Fortekor Plus; Elanco Animal Health) was tested in dogs with congestive heart failure (CHF) caused by myxomatous mitral valve disease (MMVD) in a three-arm, masked, randomized, non-inferiority clinical trial in Japan. The test group (n = 34) received Fortekor Plus twice daily. Two control groups received registered formulations of benazepril (Fortekor; Elanco Animal Health) and pimobendan (Vetmedin; Boehringer Ingelheim Vetmedica)... -
Effects of induced endometritis on uterine blood flow in cows as evaluated by transrectal Doppler sonography
Letizia Debertolis, Gaetano Mari, Barbara Merlo, Sabine Merbach, Heinz-Adolf Schoon, Eleonora Iacono, Heinrich Bollwein 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 2호 8 189-197 (9 pages)
described earlier [4]. Briefly, with the ultrasound transducer oriented transversely and faced dorsally, ..PAGE:3 Doppler sonography in bovine endometritis 191 www.vetsci.org Table 1. Schedule of investigations and treatments Day (h) B mode US Doppler US PGF2 GnRH analogue Policresulen Blood Biopsy 0 ＋ ＋ 2 ＋ ＋ 3 ＋ ＋ 4 ＋ 6 (0 h) ＋ ＋ ＋ 6 (1 h) ＋ ＋ 7 (12 h)... This study was conducted to evaluate the effects of induced endometritis on uterine blood flow in cows. Transrectal Doppler sonography was performed on uterine arteries of six cyclic cows before and for 4 days after inducing acute endometritis by intrauterine infusion of 720 mg of policresulen, and for 4 days of the following estrous cycle. Time-averaged maximum velocity (TAMV) increased (p < 0.001) and pulsatility index (PI) decreased (p < 0.0001) within 1 h of policresulen... -
Reduction of adult hippocampal neurogenesis is amplified by aluminum exposure in a model of type 2 diabetes
Sung Min Nam, Jong Whi Kim, Dae Young Yoo, Hyo Young Jung, Jung Hoon Choi, In Koo Hwang, Je Kyung Seong, Yeo Sung Yoon 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 1호 2 13-20 (8 pages)
were 6 to 10 weeks old. This schedule was adopted because Al-induced brain dysfunction and accumulation at this concentration in previous studies [21,32]. All animals were euthanized at 16 weeks of age. Body weight and blood glucose levels To confirm the effects of Al treatment on diabetic model animals, body weight and blood glucose (fed glucose) levels were measured on the last day of the... In this study, we investigated the effects of chronic aluminum (Al) exposure for 10 weeks on cell proliferation and neuroblast differentiation in the hippocampus of type 2 diabetic rats. Six-week-old Zucker diabetic fatty (ZDF) and Zucker lean control (ZLC) rats were selected and randomly divided into Al- and non-Al-groups. Al was administered via drinking water for 10 weeks, after which the animals were sacrificed at 16 weeks of age. ZDF rats in both Al- and non-Al-groups showed increases in... -
A study of experimental autoimmune encephalomyelitis in dogs as a disease model for canine necrotizing encephalitis
Jong-Hyun Moon, Hae-Won Jung, Hee-Chun Lee, Joon-Hyeok Jeon, Na-Hyun Kim, Jung-Hyang Sur, Jeongim Ha, Dong-In Jung 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 2호 10 203-211 (9 pages)
magnetic resonance imaging (MRI) after immunization, and 3) nucleated cell pleocytosis identified ..PAGE:3 EAE in dogs as a NE model 205 www.vetsci.org Table 2. Immunization and clinical evaluation schedule for this study including neurological examination, MRI, and cerebrospinal fluid (CSF) analysis Days after immunization Clinical assessment (neurological exam) MRI CSF analysis Immunization ... In the present study, the use of dogs with experimental autoimmune encephalomyelitis (EAE) as a disease model for necrotizing encephalitis (NE) was assessed. Twelve healthy dogs were included in this study. Canine forebrain tissues (8 g), including white and grey matter, were homogenized with 4 mL of phosphate-buffered saline for 5 min in an ice bath. The suspension was emulsified with the same volume of Freund’s complete adjuvant containing 1 mg/mL of killed Mycobacterium tuberculosis H37Ra.... -
Differential expression of thymic DNA repair genes in low-dose-rate irradiated AKR/J mice
Jin Jong Bong, Yu Mi Kang, Suk Chul Shin, Seung Jin Choi, Kyung Mi Lee, Hee Sun Kim 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2013, 제 14권 제 3호 6 271-279 (9 pages)
12-h lighting schedule (200∼ 300 Lux; 08：00 to 20：00). After a 1-week adaptation period, 15 mice were placed in a polycarbonate cage and provided with γ-sterilized pellets and autoclaved water ad libitum. Five mice each were assigned to the sham-irradiated group, HDR-irradiated group and LDR-irradiated group. All procedures were reviewed by the institutional Animal Care and Use Committee... (Cs, 0.7 mGy/h, 2.1 Gy) γ-irradiation facility developed less spontaneous thymic lymphoma and survived longer than those receiving sham or high-dose-rate (HDR) (Cs, 0.8 Gy/min, 4.5 Gy) radiation. Interestingly, histopathological analysis showed a mild lymphomagenesis in the thymus of LDR-irradiated mice. Therefore, in this study, we investigated whether LDR irradiation could trigger the expression of thymic genes involved in the DNA repair process of AKR/J mice. The enrichment analysis of Gene... -
Inhibitory effects of interleukin-10 plasmid DNA on the development of atopic dermatitis-like skin lesions in NC/Nga mice
Bock-Gie Jung, Sun-Ju Cho, Jae-Hyung Ko, Bong-Joo Lee* 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2010, 제 11권 제 3호 6 213-220 (8 pages)
days after the third application of 0.2% (w/v) DNCB solution. The experiment schedule is shown in Fig. 1. Evaluation of clinical skin severity The severity of dermatitis was evaluated by scoring clinical ..PAGE:3 Interleukin-10 plasmid DNA suppressive effect 215 Fig. 1. Induction of dermatitis and interleukin (IL)-10 plasmid DNA injection schedule. Dorsal regions of mice were shaved on day 0.... Interleukin (IL)-10 exerts potent anti-inflammatory effects by suppression of both T-help (Th) 1 and Th2 cells. Previous studies have reported that IL-10 can ameliorate various inflammatory disorders. The present study was performed to examine whether IL-10 plasmid DNA could suppress development of atopic dermatitis (AD)-like skin lesions in NC/Nga mice, as an initial step towards the development of an appliance for use in dogs with AD. Intradermal injection of IL-10 plasmid DNA markedly...