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Anti-tumor Effects of Canine and Human Adipose Tissue-derived Mesenchymal Stem Cells in a Xenograft Mouse Model for Melanoma
Jin ok Ahn, Ye rin Coh, Hee woo Lee, Il seob Shin, Sung keun Kang, Hwa young Youn 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 춘계학술심포지움 84 182-182 (1 pages)
Canine and Human Adipose Tissue-derived Mesenchymal Stem Cells in a Xenograft Mouse Model for Melanoma Jin-ok Ahn 1 , Ye-rin Coh 1 , Hee-woo Lee 1 , Il-seob Shin 2 , Sung-keun Kang 2 , Hwa-young Youn *1 1 Department of Veterinary Internal Medicine and Research Institute for Veterinary Medicine, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea; 2 Stem Cell... -
Therapeutic effect of human adipose tissue-derived mesenchymal stem cells in a L-arginine induced severe acute pancreatitis mouse model
Qiang Li, Woo Jin Song, Sang Cheol Park, Bo Yeon Lee, Kyeong Kweon, Hyung Kyu Chae, Hyeon Jin Kim, Su Yeon Kim, Hye Mi Yang, Hwa Young Yo 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 366 391-391 (1 pages)
of human adipose tissue-derived mesenchymal stem cells in a L-arginine induced severe acute pancreatitis mouse model Qiang Li 1, Woo-Jin Song 1, Sang-Cheol Park 1, Bo-Yeon Lee 1, Kyeong Kweon 1, Hyung-Kyu Chae 1, Hyeon-Jin Kim 1, Su-Yeon Kim 1, Hye-Mi Yang 1, Hwa-Young Youn *1 1Department of Veterinary Internal Medicine, College of Veterinary Medicine, Seoul National University, Gwanak-ro,... -
Prediction of Pharmacokinetics and Penetration of Moxifloxacin in Human with Intra-Abdominal Infection Based on Extrapolated PBPK Model
LiQinZhu, JianWeiYang, YuanZhang, YongMingWang, JianLeiZhang, YuanYuanZhao, WeiLinDong 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.2 3 99-104 (6 pages)
in rats. And then human physiological and the metabolic parameters were substituted into the model. K m and V max values of moxifloxacin used in the human model were taken from Senggunprai et al. [21]. And then moxiflo- xacin concentrations in different tissues in man could be predicted based on the establ ished model. Thus, the model would be extrapolated to human. Validation of PBPK model... a physiologically based pharmacokinetic (PBPK) model in intra- abdominal infected rats, and extrapolate it to human to predict moxifloxacin pharmacokinetics profiles in various tissues in intra-abdominal infected human. 12 male rats with intra- abdominal infections, induced by Escherichia coli, received a single dose of 40 mg/kg body weight of moxifloxacin. Blood plasma was collected at 5, 10, 20, 30, 60, 120, 240, 480, 1440 min after drug injection. A PBPK model was developed in rats and... -
Suppression of the growth of human choriocarcinoma cellsby therapeutic neural stem cells expressing cytosine deaminase and interferon- β in cellularand xenografte mouse models
Goen Tae Park, Kyung Chul Choi 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 300 498-498 (1 pages)
in mRNA and protein expressions of cell cyclerelated genes by CS were measured by reverse-transcription(RT)-PCR and Western blot assay. Results: The extracts of CS (CSE) were collected from a standard cigarette, 3R4F,and two commercial cigarettes, respectively, solubilized in 0.1% PBS, andquantified based on the concentration of nicotine included in CS. JEG-3 cellswere cultured with CSE of... -
Exposure of cigarette smoke extract repressed cellviability of placental cells via regulation of cell cycle related genes in a placentacell model
Hae Miru Lee, Kyung Chul Choi 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 299 497-498 (2 pages)
LC and CP, while down-regulatedby E2. Finally, in xenografted mouse model transplanted with BG-1 human ovariancancer cells, E2 significantly increased the tumor volume compare to a negativecontrol, but LC did not. Conclusions: Taken together, theseresults suggest that LC and CP may possess estrogenic potentials by stimulatingthe growth of BG-1 ovarian cancer cells via partially ER signaling... -
Poncirin Induced Fas-Dependent and Mitochondrial Independent Apoptotic Cell Death in AGS Human Gastric Cancer Cells
Venu Venkatarame Gowda Saralamma, Gyeong Eun Hong, Silvia Yumnam, Suchismita Raha, Ho Jeong Lee, Jeong Doo Heo, Sang Joon Lee, Gon Sup 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 춘계학술심포지움 142 212-213 (2 pages)
of Poncirin on AGS human gastric cancer cell. MTT assay was conducted to evaluate cell vi ability, Flow cytometry was employed for cell cycle analysis, DAPI staining and DNA fragmentation assay was used for analyzing nuclear fragmentation and DNA condensation, Western blot was done to analysis the apoptotic related protein. All the Data are expressed as the mean ± standard deviation(SD) of... -
Autophagy flux plays a pivotal role in LPS-mediated inflammation via TLR4 and NF-κB activation in primary human keratinocytes
Ji Hong Moon, Ju Hee Lee, You Jin Lee, Jae Won Seol, Nazim Uddin, Rasheduzzaman, Sang Youel Park 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 252 330-331 (2 pages)
the mechanism underlying this interactionin normal human epidermal keratinocytes (NHEKs). Materials and Methods: NHEK (human primary keratinocytes) were maintained in KGM-Gold medim (Lonza) at standard conditions. Real-time quantitative reverse transcription polymerase chain reaction (qRT-PCR) and western blotting were performed to detect gene products and proteins involved in NF-κB-p65,... -
Development of In Vitro Cellular Circadian Rhythm Model to Test the Effects of Neurotoxicants on Circadian Rhythm
Young Il Park, Hee Yi, Seok Jin Kang, So Ryeon Hwang, JI Hyun Bang, Jae Young Song, Hyun Ok Ku, Helmut Zarbl, Hwan Goo Kang, Mingzhu Fang 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 147 270-270 (1 pages)
antioxidants such as MSC and NAC that were known to reduce neurotoxicity can prevent the loss of, or restore a normal pattern of cellular circadian rhythm. Conclusions: Given the lack of human data on how disruption of circadian rhythm contributes to neurotoxicity, there is a critical need to establish and validate an in vitro circadian reporter assays in neural cells. This in vitro model... -
Temozolomide reduced the side population in human malignant mesothelioma cell lines
Na Yon Kim, Myung Chul Kim, Hong Seok Lee, Yu Ri Seo, Yong-baek Kim 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 춘계학술심포지움 104 140-141 (2 pages)
and Fisheries (IPET) through Advanced Production Technology Development Program, funded by Ministry of Agriculture, Food and Rural Affairs (MAFRA) (Grant number: 315005-3), Republic of Korea 기 타 P-94 Education and Standard of Animal Welfare in Poultry farms Hong-Kook Kim 1, Ha-Young Kim 1, Hye-Won Lee 1 Byeong-Soo Kim *1 1Department of Companion & Laboratory Animal Science, Kongju -
Developmentof an EX vivo Porcine Lung Model for Studying Respiratory Viral Infections
Myeon Sik Yang, Zhou Zixiong, Amina Khatun, Salik Nazki, Chang Gi Jeong, Won Il Kim, Sang Myeong Lee, Chae Woong Lim, Bum-seok Kim 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 321 384-384 (1 pages)
laws, regulations, recommendations in relation to Korean human an d veterinary medical devices and other countries such as U.S.A., EU, and Japan. The literature search was perfomed to review varies types of definition, criteria of classification & scope, regulatory approval process to permit, standard and specification, application of good manufacturing practices(GMP) requirement, safety &...


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