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Detection of Lung Nodule on Temporal Subtraction Images Based on Artificial Neural Network
Tokisa. Takumi, Miyake. Noriaki, Maeda. Shinya, Kim. Hyoung-Seop, Tan. Joo Kooi, Ishikawa. Seiji, Murakami. Seiichi, Aoki. Takatoshi 한국지능시스템학회 International journal of fuzzy logic and intelligent systems 6 Pages
한국지능시스템학회 International journal of fuzzy logic and intelligent systems 2012, Vol.12 No.2 137-142 (6 pages)
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영상 Subtraction을 이용한 이동 물체 감시 시스템
이승현, 류충상 한국안전학회 한국산업안전학회지 7 Pages
한국안전학회 한국산업안전학회지 1997, Vol.12 No.3 60-66 (7 pages)
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Subtraction법을 이용한 악관절 X-선사진 판독에 관한 연구
라춘화, 유동수, Na. Choon-Wha, Yoo. Dong-Soo 대한구강악안면방사선학회 齒科放射線 7 Pages
대한구강악안면방사선학회 齒科放射線 1987, Vol.17 No.1 175-181 (7 pages)
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Real time observation of mouse fetal skeleton using a high resolution X-ray synchrotron
Dong Woo Chang, Bora Kim, Jae Hoon Shin, Young Min Yun, Jung Ho Je, Yeu kuang Hwu, Jung Hee Yoon, Je Kyung Seong 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2011, 제 12권 제 2호 1 107-114 (8 pages)
addition, synchrotron-based K-edge digital subtraction angiography is another imaging technique that is highly sensitive to low concentrations of contrast agents. It has been recently reported that K-edge digital subtraction angiography is particularly useful for studying neurovascular pathology in pigs [21]. In teratologic studies, experiments investigating the effect ..PAGE:2 108 Dong Woo... The X-ray synchrotron is quite different from conventional radiation sources. This technique may expand the capabilities of conventional radiology and be applied in novel manners for special cases. To evaluate the usefulness of X-ray synchrotron radiation systems for real time observations, mouse fetal skeleton development was monitored with a high resolution X-ray synchrotron. A non-monochromatized X-ray synchrotron (white beam, 5C1 beamline) was employed to observe the skeleton of mice under... -
Frequencies of Micronuclei in Peripheral Lymphocytes in Korean Populations after Chronic Low-dose Radiation Exposure
Mi-Young An and Tae-Hwan Kim 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 3호 11 213-218 (6 pages)
counted by light microscope (LM). The number of observed MN was obtained by subtraction of the number of cells scored as MN in the control samples from the total number of those cells in the separated groups. The morphological findings of observed MN were typical in lymphocytes. As shown in Fig. 1, the average numbers of MN induced, obtained by pooling the LM data of subjects, are presented as a... correlated with age, sex and life-style factors. So far, it is evident that with regard to the application of MN assay all future studies have to take into account the influence of age, gender, and life-style. In Conclusion, using micronuclei assay technique a large population can be easily monitored. This study illustrated that the MN assay may provide a high potential to ensure appropriate quality control and standard documentation protocol that can be used to monitor a large population expos... -
Antidepressant drug paroxetine blocks the open pore of Kv3.1 potassium channel
HyangMiLee, OkHeeChai, SangJuneHahn, BokHeeChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.1 8 71-80 (10 pages)
of 2-3 MΩ when filled with the intracellular pipette solution. For whole-cell recordings, the membrane capacitance and 80% of the series resistance were compensated by amplifier circuits. Leak subtraction was not used. The sampling rate was 5 kHz and the currents were low-pass fil- tered at 2 kHz through a four-pole Bessel filter. The generation of voltage-clamp pulses and data acquisition... inhibitor (SSRI), interacts with ion channels that modulate neuronal excitability, we examined the effects of paroxetine on Kv3.1 potassium channels, which contribute to high-frequency firing of interneurons, using the whole-cell patch-clamp technique. Kv3.1 channels were cloned from rat neurons and expressed in Chinese hamster ovary cells. Paroxetine reversibly reduced the amplitude of Kv3.1 current, with an IC50 value of 9.43 µM and a Hill coefficient of 1.43, and also accelerated the... -
The advantage of topographic prominence-adopted filter for the detection of short-latency spikes of retinal ganglion cells
JungryulAhn, Myoung-HwanChoi, KwangsooKim, SolomonS.Senok, Dong-ilDanCho, Kyo-inKoo, YongsookGoo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.5 10 555-563 (9 pages)
such as frequency based filtering [17], tetro- dotoxin application [13,18,19], template subtraction method [20], sample and interpolate technique [21], and algorithmic approach e.g. subtraction of artifacts by local polynomial approximation (SALPA) [22-24]. All fore-mentioned methods have mutually exclusive pros and cons. Therefore, in our previous paper, we pro- posed topographic prominence... valid and useful for artifact subtraction. In this study, we compared the performance of forward backward (FB) filter only vs. TP-adopted FB filter for artifact subtraction. From the extracted retinae of rd1 mice, we recorded RGC spikes with 8×8 multielectrode array (MEA). The recorded signals were classified into four groups by distances between the stimulation and recording electrodes on MEA (200-400, 400-600, 600-800, 800-1000 μm). Fifty cathodic phase-1st biphasic current pulses (duration... -
Lamotrigine, an antiepileptic drug, inhibits 5-HT3 receptor currents in NCB-20 neuroblastoma cells
KiJungKim, SeungHyunJeun, Ki-WugSung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.2 4 169-177 (9 pages)
a gigaohm seal was formed. Capacitive currents were compensated with analog compensation, but leak subtraction was not used in this study. After achieving a whole-cell configuration, a variable amount of current run-down was typically observed for several minutes. To minimize run-down condition, we waited at least 10 min after getting whole-cell configuration, and drug applications were... Lamotrigine is an antiepileptic drug widely used to treat epileptic seizures. Using whole-cell voltage clamp recordings in combination with a fast drug application approach, we investigated the effects of lamotrigine on 5-hydroxytryptamine (5-HT)3 receptors in NCB-20 neuroblastoma cells. Coapplication of lamotrigine (1~300 μM) resulted in a concentration-dependent reduction in peak amplitude of currents induced by 3 μM of 5-HT for an IC50 value of 28.2±3.6 μM with a Hill coefficient of... -
Blockade of Kv1.5 channels by the antidepressant drug sertraline
HyangMiLee, SangJuneHahn, BokHeeChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.2 8 193-200 (8 pages)
compensated at 80% with the amplifier, while leak subtraction was not used. The generation of voltage commands and acquisition of data were controlled with pClamp 10.1 software (Molecular Devices) running on an IBM-compatible Pentium computer. Recording chamber (RC-13, Warner Instrument Corporation, Hamden, CT, USA) was continuously perfused with bath solution (see below for composition) at... the action of sertraline on Kv1.5, which is one of cardiac ion channels. The effect of sertraline on the cloned neuronal rat Kv1.5 channels stably expressed in Chinese hamster ovary cells was investigated using the whole-cell patch-clamp technique. Sertraline reduced Kv1.5 whole-cell currents in a reversible concentrationdependent manner, with an IC 50 value and a Hill coefficient of 0.71 μM and 1.29, respectively. Sertraline accelerated the decay rate of inactivation of Kv1.5 currents without...


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