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전체 선택해제
총 42건 검색
본문검색 결과만 보기
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Minimal Amount of Insulin Can Reverse Diabetic Heart Function Sarcoplasmic Reticulum Ca2+ Transport and Phospholamban Protein Expression
HaeWonKim, YongSunCho, YunSongLee, EunHeeLee, HeeRanLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.2 7 175-182 (8 pages)
In the present study, the underlying mechanisms for diabetic functional derangement and insulin effect on diabetic cardiomyopathy were investigated with respect to sarcoplasmic reticulum (SR) Ca2-ATPase and phospholamban at the transcriptional and translational levels. The maximal Ca2 uptake and the affinity of Ca2-ATPase for Ca2 were decreased in streptozotocin-induced diabetic rat cardiac SR, however, even minimal amount of insulin could reverse both parameters.... -
Identification of the Distribution Function of the Preisach Model using Inverse Algorithm
Koh. Chang-Seop, Ryu. Jae-Seop 대한전기학회 KIEE international transactions on electrical machinery and energy conversion systems 6 Pages
대한전기학회 KIEE international transactions on electrical machinery and energy conversion systems 2002, No.0 168-173 (6 pages)
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유아의 언어발달 정도에 대한 기초연구
단현국(Dan Hyun Kook), 한은희(Han Eun Hee), 한유진(Han Yoo Jin) 한국교원대학교 유아교육연구소 한국유아교육연구 33 Pages
한국교원대학교 유아교육연구소 한국유아교육연구 2012, 제 14권 제 1호 6 153-185 (33 pages)
본 연구는 대전광역시와 울산광역시에 소재한 8개 공립유치원 13학급에 재원중인 5세 학급 유아 255명(남아: 120명, 여아: 135명)을 대상으로, 취학 전 아동의 수용언어 및 표현언어 발달 척도에서 유아의 생활연령에 따라 언어발달을 어떻게 보이고 있으며 발달경향은 지역과 성별에 따라 차이가 있는지를 알아보고자 하였다. 그 결과, 첫째, 5․6세 유아의 언어능력은 수용언어 능력이 표현언어 능력보다 먼저 발달하고 있었다. 둘째, 수용언어 능력은 5세 1개월부터 발달이 이루어지고, 표현언어 능력은 5세 7개월 이후부터... -
Tissue-specific expression of the NOD-like receptor protein 3 in BALB/c mice
Zhiqiang Huang, Meng Yu, Shuang Tong, Kun Jia, Rongchang Liu, Heng Wang, Shoujun Li*, Zhangyong Ning* 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 2호 1 173-177 (5 pages)
to further elucidate its function in innate immunity in this commonly used laboratory animal model. NLRP3 mRNA expression levels and tissue distribution of the protein were investigated by real-time quantitative PCR and immunohistochemical analyses, respectively. NLRP3 mRNA expression was higher in the kidney and inguinal lymph nodes than in other tissues. Cytoplasmic expression of NLRP3 was detected in the epithelial reticular cells of the spleen and thymus, lymphocytes in the inguinal lymph... -
Risk factors associated with bacteriological cure, new infection, and incidence of clinical mastitis after dry cow therapy with three different antibiotics
Yasmin Gundelach, Elke Kalscheuer, Henning Hamann, Martina Hoedemaker* 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2011, 제 12권 제 3호 5 227-233 (7 pages)
Factors affecting bacteriological cure rates (BCR) and new intramammary infections (IMI) during the dry period as well as clinical mastitis (CM) during early lactation were investigated in 414 German Holstein dairy cows receiving dry cow therapy. Cows were treated with either benethamine benzylpenicillin (300,000 IU), penethamate hydriodide (100,000 IU), and framycetin sulphate (100 mg, n = 136), or cefquinome (150 mg, n = 135), or benzathine cloxacillin (1,280 mg, n = 143). Overall BCR, IMI,... -
Risk factors for delayed conception in Korean dairy herds
Ill-Hwa Kim, Hyun-Gu Kang 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 4호 13 381-385 (5 pages)
Delayed conception is defined as an interval of greater than 90 days postpartum before a cow becomes pregnant again. In this study, the risk factors for delayed conception in Korean dairy herds were determined by evaluating several reproductive factors in individual cows. The following data was recorded from 1,012 pregnancies in eight dairy herds (designated A-H) from July 2001 to June 2006: herd, cow parity, repeated animal (cows included 2, 3, or more times), calving season, calving condition... -
General pharmacological profiles of bee venom and its water soluble fractions in rodent models
Hyun-Woo Kim, Young-Bae Kwon, Tae-Won Ham, Dae-Hyun Roh, Seo-Yeon Yoon, Seuk-Yun Kang, Il-Suk Yang, Ho-Jae Han, Hye-Jung Lee, Al 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2004, 제 5권 제 4호 5 309-318 (10 pages)
Recently, the antinociceptive and anti-inflammatory efficacy of bee venom (BV, Apis mellifera) has been confirmed in rodent models of inflammation and arthritis. Interestingly, the antinociceptive and anti-inflammatory effect of whole BV can be reproduced by two water-soluble fractions of BV (>20 kDa:BVAF1 and<10 kDa: BVAF3). Based on these scientific findings, BV and its effective water-soluble fractions have been proposed as potential anti-inflammatory and antinociceptive pharmaceuticals.... -
Analysis of in vitro apoptosis induced by virulent Korean isolate of classical swine fever virus in peripheral blood B cell line
Seon Mi Kim , Seong In Lim , Jae Young Song , Bang Hun Hyun , 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 4 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2012, 제 52권 제 4호 6 259-262 (4 pages)
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Roles of Gonadal Steroids on Exocrine Secretion of Isolated Perfused Rat Pancreas
HyungSeoPark, SeHoonKim, HyoungJinPark, MeeYoungLee, YoungHeeHan 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.4 5 217-221 (5 pages)
To clarify the roles of gonadal steroids on pancreatic exocrine secretion, effects of progesterone and estradiol-17β on spontaneous and secretagogue-induced exocrine response of isolated perfused rat pancreas were investigated. Intra-arterial infusion of progesterone resulted in significant increase of the spontaneous pancreatic fluid and amylase secretion dose-dependently. However, estradiol-17β did not exert any influence on spontaneous pancreatic exocrine secretion. Exogenous secretin,... -
Molecular Mechanism of Pancreatic Bicarbonate Secretion
MinGooLee, JeWooKim, KyungHwanKim, ShmuelMuallem 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2002, Vol.6 No.3 1 131-138 (8 pages)
Thanks to recent progress in availability of molecular and functional techniques it became possible to search for the basic molecular and cellular processes that mediate and control HCO3 and fluid secretion by the pancreatic duct. The coordinated action of various transporters on the luminal and basolateral membranes of polarized epithelial cells mediates the transepithelial HCO3 transport, which involves HCO3 absorption in the resting state and HCO3 secretion in the... -
Tissue-Specific Regulation of Angiotensinogen and Angiotensin II Receptor Gene Expression in Deoxycorticosterone Acetate-Salt Hypertensive Rats
JongUnLeeMiRaAn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.3 9 315-320 (6 pages)
Molecular regulation of the renin-angiotensin system (RAS) was investigated in deoxycorticosterone acetate (DOCA)-salt hypertension. The expression of renin, angiotensinogen and angiotensin II receptor genes in the kidney and liver was determined by Northern blot analysis in rats which were made DOCA-salt hypertensive over the period of 2 or 4 weeks. Along with the hypertension, renin mRNA was decreased in the remnant kidney. The expression of angiotensinogen gene was not significantly altered... -
Gene Expression of Intrarenal Renin-angiotensin System in Streptozotocin-induced Diabetic Rats
EunKyoungYang, InKyeomKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.1 6 45-53 (9 pages)
In humans and many animal models with chronic progressive renal diseases, angiotensin-converting enzyme (ACE) inhibitor markedly attenuates the progression of nephropathy. Several studies have reported augmented gene expression and redistribution of renal renin in partial nephrectomized rats. Although precise mechanism(s) is not known, the renin-angiotensin system (RAS) may play an important role in the progression of renal diseases. Thus, this study was undertaken to examine the gene... -
Human Cerebellar Activation during Painful Cold Stimulation：a Functional Magnetic Resonance Imaging Study
Seung-Schik Yoo, Byung Gil Choi, Chang Uk Lee, Bum Soo Kim, , Su Jung Yoon, Soo Jung Lee, Tae Kim, Jung Jin Kim, Chul Lee, In Ho Paik 대한신경정신의학회 신경정신의학 7 Pages
대한신경정신의학회 신경정신의학 2001, 제 40권 제 4호 16 727-733 (7 pages)
연구목적： 본 연구에서는 기능적 자기공명영상법(fMRI)을 이용하여 동통 한랭 자극 동안의 소뇌 활동정도를 알아보 았다. 방 법： 6명의 건강한 자원자들을 선발하여 1.5 Tesla MR scanner 안에 누워 있는 동안 그들의 좌측 손에 0~3℃의 얼음주머니를 올려놓아 동통 한랭 자극을 주었다. 자극과 연관된 BOLD(blood oxygenation level dependent) 반응을 평가하기 위해 일련의 susceptibility-weighted MR image를 측정하였고 대뇌활동 영 역을 시각화하고 정량화하는 statistical parametric map을 작성하였다. 결 과： 한랭 자극으로... -
신경심리 검사에 나타난 남자 정신분열병 환자와 조증 환자의 전두엽 기능 장애
이황희, 박영남 대한신경정신의학회 신경정신의학 11 Pages
대한신경정신의학회 신경정신의학 1996, 제 35권 제 1호 5 39-49 (11 pages)
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당뇨성 심근질환에서의 근장그물 기능이상과 그 작용기전
김혜원(Hae Won Kim), 이희란(Hee Ran Lee), 장연진(Yeon Jin Jang), 박형섭(Hyoung-Sup Park), 박소영(So Young Park) 대한약리학회 대한약리학잡지 8 Pages
대한약리학회 대한약리학잡지 1993, 제 29권 제 2호 5 195-202 (8 pages)
스트렙토조토신으로 당뇨를 유발시킨 쥐의 심근 근장그물에서 칼슘이동이 저하됨을 볼 수 있었다. 칼슘이동의 저하는 최대칼슘 uptake의 감소와 칼슘에 대한 affinity의 감소로 나타났다. 이러한 심근 근장그물의 기능저하가 나타나는 작용기전이 심근 근장그물 단백의 산화성 손상과 관계가 있는지를 살펴보았다. 당뇨쥐에서는 glycohemoglobin과 carbonyl group의 양이 현저히 증가됨을 볼 수 있었다. 한편으로 cyclic AMP 의존성 protein kinase의 catalytic subunit에 의한 phospholamban 인산화에 의해 심근 근장고물 칼슘이동의... -
Neuroendocrine Control of Gonadotropin Secretion during the Menstrual Cycle
Ryu Kyung-Za 대한약리학회 대한약리학잡지 20 Pages
대한약리학회 대한약리학잡지 1987, 제 23권 제 2호 1 57-76 (20 pages)
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An Integrated Modeling Approach for Predicting Potential Epidemics of Bacterial Blossom Blight in Kiwifruit under Climate Change
Kwang-Hyung Kim, Young Jin Koh 한국식물병리학회 The Plant Pathology Journal 14 Pages
한국식물병리학회 The Plant Pathology Journal 2019, 35권 5호 7 459-472 (14 pages)
The increasing variation in climatic conditions under climate change directly influences plant-microbe interactions. To account for as many variables as possible that may play critical roles in such interactions, the use of an integrated modeling approach is necessary. Here, we report for the first time a local impact assessment and adaptation study of future epidemics of kiwifruit bacterial blossom blight (KBB) in Jeonnam province, Korea, using an integrated modeling approach. This study...
