자료유형
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Parsing KEGG XML Files to Find Shared and Duplicate Compounds Contained in Metabolic Pathway Maps: A Graph-Theoretical Perspective
Kang. Sung-Hui, Jang. Myung-Ha, Whang. Ji-Young, Park. Hyun-Seok 한국유전체학회 Genomics & informatics 6 Pages
한국유전체학회 Genomics & informatics 2008, Vol.6 No.3 147-152 (6 pages)
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Enhanced Production of Astaxanthin by Metabolic Engineered Isoprenoid Pathway in Escherichia coli
이재형, 서용배, 김영태, Lee. Jae-Hyung, Seo. Yong-Bae, Kim. Young-Tae 한국생명과학회 생명과학회지 7 Pages
한국생명과학회 생명과학회지 2008, Vol.18 No.12 1764-1770 (7 pages)
이 연구의 목적은 생물공학적으로 이소프레노이드 생합성 유전자를 클로닝하여 이들을 형질전환시킨 대장균을 제조하여 이들을 숙주로 사용하여 아스타잔틴의 생산을 증가시키는 것이다. 본 연구진은 선행연구에서 Paracoccus haeundaensis로부터 아스타잔틴 생산에 관여하는 6개의 아스타잔틴 생합성 유전자군을 보고하였고, 이들 유전자들을 발현 벡타(pCR-XL-TOPO-Crt)에 재조합한 후 이 벡터를 대장균에 형질 전환시켜서 건조중량으로 400 ${mu}g$/g의 아스타잔틴을 생산하였다. 아스타잔틴의 생산성을 증가시키기 위해서... -
Real-Time PCR Analysis of Metabolic Pathway of PHB in Acidiphilium cryptum DX1-1
Xu. Ai-Ling, Xia. Jin-Lan, Liu. Ke-Ke, Li. Li, Yang. Yu, Nie. Zhen-Yuan, Qiu. Guan-Zhou 한국미생물생명공학회 Journal of microbiology and biotechnology 7 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 2010, Vol.20 No.1 71-77 (7 pages)
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Investigation of the Central Carbon Metabolism of Sorangium cellulosum: Metabolic Network Reconstruction and Quantification of Pathway Fluxes
Bolten. Christoph J., Heinzle. Elmar, Muller. Rolf, Wittmann. Christoph 한국미생물생명공학회 Journal of microbiology and biotechnology 14 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 2009, Vol.19 No.1 23-36 (14 pages)
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Estimation of Theoretical Yield for Ethanol Production from D-Xylose by Recombinant Saccharomyces cerevisiae Using Metabolic Pathway Synthesis Algorithm
Lee. Tae-Hee, Kim. Min-Young, Ryu. Yeon-Woo, Seo. Jin-Ho 한국미생물생명공학회 Journal of microbiology and biotechnology 5 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 2001, Vol.11 No.3 384-388 (5 pages)
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Could Organic Solvents Be Used for the Alteration of Flux of Hydrophobic Intermediates through a Metabolic Pathway in Microorganismsulcorner
Zucchi. Gioia, Khan. Jeffrey-A., Vulfson. Evgeny-N. 한국미생물생명공학회 Journal of microbiology and biotechnology 4 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 1998, Vol.8 No.6 719-722 (4 pages)
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Effect of low intensity pulsed ultrasound in activating the mitogen-activated protein kinase signaling pathway and inhibition inflammation cytokine synthesis in chondrocytes
Eun-Jung Kim, Gye-Yeop Kim 물리치료재활과학회 Physical Therapy Rehabilitation Science 5 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2014, 제 3권 제 1호 6 33-37 (5 pages)
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BDNF/ERK pathway in TMT-induced neurotoxicity
Su eun Lee, Mi young Yang, Ju hwan Kim, Jin wook Kim, So hi Kang, Woo seok Ahn, Sung Ho Kim, Jong Choon Kim, Tae kyun Shin, Heh In Im, Ho 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 267 481-481 (1 pages)
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In silico analysis of putative drug and vaccine targets of the metabolic pathways of Actinobacillus pleuropneumoniae using a subtractive/comparative genomics approach
Biruk T. Birhanu, Seung-Jin Lee, Na-Hye Park, Ju-Beom Song, Seung-Chun Park 대한수의학회 Journal of Veterinary Science 12 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 2호 5 188-199 (12 pages)
20 metabolic pathways that were unique and contained 273 non-homologous proteins, of which 122 were essential. Of the 122 essential proteins, there were 95 cytoplasmic proteins and 11 transmembrane proteins, which are potentially suitable for drug and vaccine targets, respectively. Among these, 25 had at least one hit in DrugBank, and three had similarity to metabolic proteins from Mycoplasma hyopneumoniae, another pathogen causing porcine respiratory disease complex; thus, they could serve as... -
Neuronal maturation in the hippocampal dentate gyrus via chronic oral administration of Artemisa annua extract is independent of cyclooxygenase 2 signaling pathway in diet-induced obesity mouse model
Hye Kyung Baek, Pan Soo Kim, Ji Ae Song, Dong-Hwa Choi, Do Eun Kim, Seung Il Oh, Sang-Kyu Park, Sung-Jo Kim, Ki-Duk Song, In Koo 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 2호 1 119-127 (9 pages)
Recently, we reported that Artemisia annua (AA) has anti-adipogenic properties in vitro and in vivo. Reduction of adipogenesis by AA treatment may dampen systemic inflammation and protect neurons from cytokine-induced damage. Therefore, the present study was undertaken to assess whether AA increases neuronal maturation by reducing inflammatory responses, such as those mediated by cyclooxygenase 2 (COX-2). Mice were fed normal chow or a high-fat diet with or without chronic daily oral... -
Involvement of the Ca signaling pathway in osteoprotegerin inhibition of osteoclast differentiation and maturation
Yingxiao Fu, Jianhong Gu, Yi Wang, Yan Yuan, Xuezhong Liu, Jianchun Bian, Zong-Ping Liu 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 2호 3 151-156 (6 pages)
The results confirmed that M-CSF + RANKL significantly increased [Ca]i and CaMKII phosphorylation in osteoclasts (p < 0.01), and that these effects were subsequently decreased by OPG treatment. Exposure to specific inhibitors of the Ca signaling pathway revealed that these changes varied between the different OPG treatment groups. Findings from the present study indicated that the Ca signaling pathway is involved in both the regulation of osteoclastogenesis as well as inhibition of osteoclast... -
Intragastric gavage with denatonium benzoate acutely induces neuronal activation in the solitary tract nucleus via the vagal afferent pathway
Hyo Young Jung, Woosuk Kim, Dae Young Yoo, Sung Min Nam, Jong Whi Kim, Jung Hoon Choi, Yeo Sung Yoon, Hye Young Kim, In Koo Hwan 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 4호 1 459-464 (6 pages)
Natural toxic substances have a bitter taste and their ingestion sends signals to the brain leading to aversive oral sensations. In the present study, we investigated chronological changes in c-Fos immunoreactivity in the nucleus tractus solitarius (NTS) to study the bitter taste reaction time of neurons in the NTS. Equal volumes (0.5 mL) of denatonium benzoate (DB), a bitter tastant, or its vehicle (distilled water) were administered to rats intragastrically. The rats were sacrificed at 0, 0.5,... -
Antepartal insulin-like growth factor concentrations indicating differences in the metabolic adaptive capacity of dairy cows
Marion Piechotta*, Lars Holzhausen, Marcelo Gil Araujo, Maike Heppelmann, Anja Sipka, Chistiane Pfarrer, Hans-Joachim Schuberth, 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 3호 2 343-352 (10 pages)
Cows with different Insulin-like Growth Factor-I (IGF-I) concentrations showed comparable expression levels of hepatic growth hormone receptor (GHR). Suppressor of cytokine signaling 2 (SOCS2), could be responsible for additional inhibition of the GHR signal cascade. The aims were to monitor cows with high or low antepartal IGF-I concentrations (IGF-I or IGF-I), evaluate the interrelationships of endocrine endpoints, and measure hepatic SOCS2 expression. Dairy cows (n = 20) were selected (240 to... -
Effects of resveratrol on the insulin signaling pathway of obese mice
Hyun Ju Hong, Wonyoung Kang, Dong Geon Kim, Dae Ho Lee, Youngjae Lee, Chang-Hoon Han* 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 2호 2 179-185 (7 pages)
compared with the levels in the HF group. In addition, the phosphorylation levels of IRS-1 (Ser636/Ser639), PI-3K p85-subunit α/γ (Tyr467/Tyr199), PDK1 (Ser241), GSK-3α (S21) and GSK-3 (Ser9), which are involved in the insulin signaling pathway, were decreased in the HF group, whereas the levels were restored to normal in the HFR group. Overall, the results show that resveratrol restores the phosphorylation levels of proteins involved in the insulin signaling pathway, which were decreased by...


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