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A two-component signal transduction system contributes to the virulence of Riemerella anatipestifer
Qing Wang, Mianmian Chen, Wei Zhang 대한수의학회 Journal of Veterinary Science 11 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 2호 12 260-270 (11 pages)
signal transduction response regulator (ArsR) and a signal transduction histidine kinase (SthK) were predicted to be located on the same operon. A mutant was constructed by deletion of both of these genes. Duck infection tests showed that genes ArsR and SthK were related to the virulence of the pathogen in vivo. Differentially expressed genes identified by comparison of in vitro and in vivo conditions provided an insight into the physiological process of RA infection and provided an opportunity... -
The signal sequence of type II porcine reproductive and respiratory syndrome virus glycoprotein 3 is sufficient for endoplasmic reticulum retention
Do-Geun Kim, Chang-Seon Song, In-Soo Choi, Seung-Yong Park, Joong-Bok Lee, Sang-Soo Lee 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2013, 제 14권 제 3호 10 307-313 (7 pages)
reticulum (ER) rather than transported to the plasma membrane of the cell. In this study, we performed confocal laser scanning microscopy analysis of variants of GP3 and foundthat the signal sequence of the GP3 led to confinement of GP3 in the ER, while the functional ortransmembrane domain did not affect its localization. Based on these results, we concludedthat the signal sequence of GP3 contains the ER retention signal, which might play an important role in assembly of viral proteins. -
Comparative proteomic analysis of outer membrane protein 43 (omp43)-deficient Bartonella henselae
Jun-Gu Kang, Hee-Woo Lee, Sungjin Ko, Joon-Seok Chae 대한수의학회 Journal of Veterinary Science 12 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 1호 9 59-70 (12 pages)
7 proteins associated with information storage and processing, and 3 proteins associated with cellular processing and signaling. By semi-quantitative reverse transcriptase polymerase chain reaction, increases in tldD, efp, ntrX, pdhA, purB, and ATPA mRNA expression and decreases in Rho and yfeA mRNA expression were confirmed in Δomp43. In conclusion, this is the first report showing that a loss of OMP43 expression in B. henselae leads to retarded proliferation. Furthermore, our proteomic data... -
Molecular characterization of duck enteritis virus CHv strain UL49.5 protein and its colocalization with glycoprotein M
Meng Lin, Renyong Jia*, Mingshu Wang, Xinghong Gao, Dekang Zhu, Shun Chen, Mafeng Liu, Zhongqiong Yin, Yin Wang, Xiaoyue Chen, A 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 3호 7 389-398 (10 pages)
and gM (a conserved protein in herpesviruses) colocalize. DEV pUL49.5 was thought to be an envelope glycoprotein with a signal peptide and two transmembrane domains. This protein was also predicted to localize in the cytoplasm and endoplasmic reticulum with a probability of 66.7%. Images taken by a fluorescence microscope at different time points revealed that the DEV pUL49.5 and gM proteins were both expressed in the cytoplasm. Overlap of the two different fluorescence signals appeared 12 h... -
An overview of calf diarrhea - infectious etiology, diagnosis, and intervention
Yong-il Cho, Kyoung-Jin Yoon* 대한수의학회 Journal of Veterinary Science 17 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 1호 1 1-17 (17 pages)
Calf diarrhea is a commonly reported disease in young animals, and still a major cause of productivity and economic loss to cattle producers worldwide. In the report of the 2007 National Animal Health Monitoring System for U.S. dairy, half of the deaths among unweaned calves was attributed to diarrhea. Multiple pathogens are known or postulated to cause or contribute to calf diarrhea development. Other factors including both the environment and management practices influence disease severity or... -
Induction of humoral responses to BHV-1 glycoprotein D expressed by HSV-1 amplicon vectors
Andrea Maria Blanc, Mabel Beatriz Berois, Lorena Magalí Tomé, Alberto L. Epstein, Juan Ramón Arbiza* 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2012, 제 13권 제 1호 9 59-65 (7 pages)
Herpes simplex virus type-1 (HSV-1) amplicon vectors are versatile and useful tools for transferring genes into cells that are capable of stimulating a specific immune response to their expressed antigens. In this work, two HSV-1-derived amplicon vectors were generated. One of these expressed the full-length glycoprotein D (gD) of bovine herpesvirus 1 while the second expressed the truncated form of gD (gDtr) which lacked the trans-membrane region. After evaluating gD expression in the infected... -
TaqMan reverse transcription polymerase chain reaction for the detection of Japanese encephalitis virus
Dong-Kun Yang, Chang-Hee Kweon, Byoung-Han Kim, Seong-In Lim, Seong-Hee Kim, Jun-Hun Kwon, Hong-Ryul Han 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2004, 제 5권 제 4호 10 345-351 (7 pages)
One step TaqMan reverse transcription polymerase chain reaction (RT-PCR) using TaqMan probe was developed for detection of Japanese encephalitis virus (JEV). Real-time RT-PCR was optimized to quantify JEV using the detection system (Rotor Gene 2000 detector) and dual-labeled fluorogenic probes. The gene specific labeled fluorogenic probe for the 3' non-translated region (3' NTR) was used to detect JEV. When the specificity of the assay using specific JEV primers was evaluated by testing three... -
서울굿 굿거리장단에서의 9소박의 특성에 관한 경험적 연구
이미경(Mikyung Lee), 송현주(Hyeonjoo Song) 한국음악교육공학회 음악교육공학 16 Pages
한국음악교육공학회 음악교육공학 2018, 제 34호 2 27-42 (16 pages)
본 연구는 우리 민속악 4박 계열 장단들 중 서울굿 음악의 타령을 부를 때 반주로 사용하는 굿거리 장단의 연주과정에서 소박 단위의 박들에 나타나는 타이밍 데이터 상의 특징적 현상을 분석하고자 하였다. 서울굿 실제 연주를 녹음한 연주에서 장군거리에 나오는 4개의 타령을 연구대상으로 하였고, 데이터의 처리방식은 오디오 파일을 중심으로 온 셋데이터를 추출하여 첫 박을 기준으로 하는 소박들의 상대적 위상값을 계산하여 그 값들의 변화를 추적하였다. 그 결과 9소박의 데이터에서 통계적으로 유의함이 발견되었고... -
Time-dependent proteomic and genomic alterations in Toll-like receptor-4-activated human chondrocytes: increased expression of lamin A/C and annexins
SeungHeeHa, HyoungKyuKim, NguyenThiTuyetAnh, NariKim, KyungSooKo, ByoungDooRhee, JinHan 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 16 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.5 8 531-546 (16 pages)
Activation of Toll-like receptor-4 (TLR-4) in articular chondrocytes increases the catabolic compartment and leads to matrix degradation during the development of osteoarthritis. In this study, we determined the proteomic and genomic alterations in human chondrocytes during lipopolysaccharide (LPS)-induced inflammation to elucidate the underlying mechanisms and consequences of TLR-4 activation. Human chondrocytes were cultured with LPS for 12, 24,and 36 h to induce TLR-4 activation. The... -
Cyclophilin A as a New Therapeutic Target for Hepatitis C Virus- induced Hepatocellular Carcinoma
JinhwaLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.5 1 375-383 (9 pages)
Hepatocellular carcinoma (HCC) related to hepatitis B virus (HBV) and hepatitis C virus (HCV) infections is thought to account for more than 80% of primary liver cancers. Both HBV and HCV can establish chronic liver inflammatory infections, altering hepatocyte and liver physiology with potential liver disease progression and HCC development. Cyclophilin A (CypA) has been identified as an essential host factor for the HCV replication by physically interacting with the HCV non structural protein... -
Genome Wide Analysis of the Potato Soft Rot Pathogen Pectobacterium carotovorum Strain ICMP 5702 to Predict Novel Insights into Its Genetic Features
Tista Mallick, Rukmini Mishra, Sasmita Mohanty, Raj Kumar Joshi 한국식물병리학회 The Plant Pathology Journal 13 Pages
한국식물병리학회 The Plant Pathology Journal 2022, 38권 2호 4 102-114 (13 pages)
Pectobacterium carotovorum subsp. carotovorum (Pcc) is a gram-negative, broad host range bacterial pathogen which causes soft rot disease in potatoes as well as other vegetables worldwide. While Pectobacterium infection relies on the production of major cell wall degrading enzymes, other virulence factors and the mechanism of genetic adaptation of this pathogen is not yet clear. In the present study, we have performed an in-depth genome-wide characterization of Pcc strain ICMP5702 isolated from... -
Suppression of Rice Stripe Virus Replication in Laodelphax striatellus Using Vector Insect-Derived Double-Stranded RNAs
Ying Fang, Jae Young Choi, Dong Hwan Park, Min Gu Park, Jun Young Kim, Minghui Wang, Hyun Ji Kim, Woo Jin Kim, Yeon Ho Je 한국식물병리학회 The Plant Pathology Journal 9 Pages
한국식물병리학회 The Plant Pathology Journal 2020, 36권 3호 8 280-288 (9 pages)
RNA interference (RNAi) has attracted attention as a promising approach to control plant viruses in their insect vectors. In the present study, to suppress replication of the rice stripe virus (RSV) in its vector, Laodelphax striatellus, using RNAi, dsRNAs against L. striatellus genes that are strongly upregulated upon RSV infection were delivered through a rice leaf-medi- ated method. RNAi-based silencing of peroxiredoxin, cathepsin B, and cytochrome P450 resulted in significant down regulation... -
Development of a Species-specific PCR Assay for Three Xanthomonas Species, Causing Bulb and Flower Diseases, Based on Their Genome Sequences
한국식물병리학회 The Plant Pathology Journal 7 Pages
한국식물병리학회 The Plant Pathology Journal 2015, 31권 3호 2 212-218 (7 pages)
In this study, we developed a species-specific PCR assay for rapid and accurate detection of three Xanthomonas species, X. axonopodis pv. poinsettiicola (XAP), X. hyacinthi (XH) and X. campestris pv. zantedeschiae (XCZ), based on their draft genome sequences. XAP, XH and XCZ genomes consist of single chromosomes that contain 5,221, 4,395 and 7,986 protein coding genes, respectively. Species-specific primers were designed from variable regions of the draft genome sequence data and assessed by a... -
강인한 베어링 결함 진단을 위한 경험 모드 분리법과 히스토그램 모델링을 이용한 특징 추출 방법
파미드 파리드, 장원철, 김종면 인문사회과학기술융합학회 예술인문사회융합멀티미디어논문지 12 Pages
인문사회과학기술융합학회 예술인문사회융합멀티미디어논문지 2014, 제 4권 제 2호 23 281-292 (12 pages)
본 논문에서는 저속으로 회전하는 유도 전동기의 베어링 결함을 검출하기 위해 경험 모드 분리법 과 히스토그램 모델링을 이용하는 방법을 제안한다. 제안한 방법은 유도 전동기에서 취득된 원신호에 EMD 기법을 적용하여 잡음으로 인한 신호의 왜곡을 최소화하고, 신호를 정규화하여 신호를 구성하 는 히스토그램의 포락선을 모델링한다. 모델링된 신호에서 부분 상관 계수와 DET(Distance Evaluation Technique) 기법을 적용하여 결함 유형별 고유한 특징을 추출 및 선택한다. 추출된 특징 을 SVR(Support Vector Regression) 분류기의... -
인공와우를 통한 말지각과 반대편 귀 사용 효과에 대한 최근 연구 고찰
오수희, 김진숙 한국청각언어재활학회 Audiology and Speech Research 12 Pages
한국청각언어재활학회 Audiology and Speech Research 2014, 제 10권 제 2호 1 87-98 (12 pages)
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시간-주파수 변환 압축에 따른 정상 성인의 한국어 단음절 숫자 인지 기능
임덕환, 원유경 한국청각언어재활학회 Audiology and Speech Research 6 Pages
한국청각언어재활학회 Audiology and Speech Research 2012, 제 8권 제 2호 7 190-195 (6 pages)
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인공와우 착용자의 주파수 여과에 따른 일음절 재인 능력
장현숙, 이지연, 유수연, ·정은조, 박홍준 한국청각언어재활학회 Audiology and Speech Research 6 Pages
한국청각언어재활학회 Audiology and Speech Research 2007, 제 3권 제 1호 9 58-63 (6 pages)
인공와우 착용인들은 청신경의 직접적인 전기적인 자극으로 상당한 청각능력(audibility)을 가지므로 말지각 능력에 향상된 결과를 보이고 있음에도 불구하고 청력에 비하여 말지각 능력이 훨씬 못 미치는 경향이 있다. 이것은 인공와우 착용인의 말지각 어려움이 청력(audibility)에 더하여 다른 요소들과도 부합되어 있음을 시사한다. 이런 말지각의 어려움은 인공와우를 통한 청각적 정보의 열약한 spectral 및 temporal resolution 등의 요소13)11)16)나 말소리 습득의 결정적 시기와 오랜 기간 동안의 청각박탈에 따른 청각적인... -
잡음대역과 SNR 변화조건에서 Binaural Masking Level Difference가 “곰/공”변별에 미치는 효과 분석
구성민, 김은옥, 정두환, 임덕환 한국청각언어재활학회 Audiology and Speech Research 4 Pages
한국청각언어재활학회 Audiology and Speech Research 2007, 제 3권 제 2호 10 154-157 (4 pages)
정상 청력인이 소리를 변별하는데 여러 변수 중에서 temporal fine structure information과 envelope information 의 두 가지 정보도 이용하게 된다.7)8) 이 두 정보를 좌우하는 요소에는 fundamental frequency, unequalled level, stimulus duration, modulation depth (index)등의 변수들이 작용한다. 이러한 변수 외에도 소리의 위상(phase)과 관련 하여 양이 청취를 이용한 소음 속에서 합성음 또는 어음변별의 향상, 어음청취력과 방향성의 개선으로 소리를 변별하는 데 BMLD(binaural masking level difference) 효과가... -
AE 신호를 이용한 조기 결함 검출을 위한 Hilbert 변환과 Hilbert-Huang 변환의 비교
구동식, 이종명, 이정훈, 하정민, 최병근, Gu. Dong-Sik, Lee. Jong-Myeong, Lee. Jung-Hoon, Ha. Jung-Min, Choi. Byeong-Keun 한국마린엔지니어링학회 한국마린엔지니어링학회지 9 Pages
한국마린엔지니어링학회 한국마린엔지니어링학회지 2012, Vol.36 No.2 258-266 (9 pages)
개발을 위해 적용되고 있으며, 그에 따르는 신호처리 기법에 대한 문제를 해결하기 위해 많은 노력을 기울이고 있다. 신호처리 기법 중 포락처리(Envelope analysis)가 베어링 결함 분석에 사용되고, Wavelet Transform은 기어 등의 결함 분석에 용이한 것으로 알려져 있다. 하지만 여전히 AE 신호를 위한 신호처리 기법은 불확실하다. 따라서 본 논문에서는 AE 시스템을 적용한 조기 결함 검출 시스템 개발을 위한 사전 연구로, AE 신호를 분석하기 위한 신호처리 기법으로 Hilbert Transform(HT)과 Hilbert-Huang Transform(HHT)에 대해...
