자료유형
발행기관
- 대한생리학회-대한약리학회(171)
- 대한수의학회(56)
- 대한약리학회(29)
- 대한생리학회(26)
- 한국식물병리학회(17)
- 한국식품과학회(10)
- 한국식품영양과학회(7)
- 대한치과교정학회(6)
- 한국수산과학회(5)
- 대한신경정신의학회(4)
- 한국미생물생명공학회(4)
- 한국탄소학회(4)
- 한방비만학회(4)
- 한국수산학회(3)
- 한국기초간호학회(2)
- 한국미생물학회(2)
- 한국생명과학회(2)
- 한국생약학회(2)
- 한국약용작물학회(2)
- 고려인삼학회(1)
- 대한치과이식임플란트학회(1)
- 대한치주과학회(1)
- 한국고분자학회(1)
- 한국미용산업학회(1)
- 한국발생생물학회(1)
- 한국보건기초의학회(1)
- 한국생물공학회(1)
- 한국유가공기술과학회(1)
- 한국응용생명화학회(1)
- 한국작물학회(1)
간행물
- THE KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY(171)
- JOURNAL OF VETERINARY SCIENCE(39)
- 대한약리학잡지(29)
- 대한생리학회지(26)
- THE PLANT PATHOLOGY JOURNAL (14)
- KOREAN JOURNAL OF VETERINARY RESEARCH(구 대한수의학회지)(12)
- 한국식품과학회지(8)
- THE KOREAN JOURNAL OF ORTHODONTICS(6)
- 대한수의학회 학술대회발표집(5)
- CARBON LETTERS(4)
- 대한한방비만학회지(4)
- 신경정신의학(4)
- 식물병연구(3)
- 한국수산과학회지(3)
- 한국수산학회지: BULLETIN OF THE KOREAN FISHERIES SOCIETY(3)
- 한국식품영양과학회지(3)
- 한국영양식량학회지(3)
- FOOD SCIENCE AND BIOTECHNOLOGY(2)
- JOURNAL OF KOREAN BIOLOGICAL NURSING SCIENCE(2)
- NATURAL PRODUCT SCIENCES(2)
- 생명과학회지(2)
- 한국미생물-생명공학회지(2)
- 한국약용작물학회지(2)
- JOURNAL OF CROP SCIENCE AND BIOTECHNOLOGY(1)
- JOURNAL OF DENTAL IMPLANT RESEARCH(1)
- JOURNAL OF FISHERIES SCIENCE AND TECHNOLOGY(1)
- JOURNAL OF FOOD SCIENCE AND NUTRITION(1)
- JOURNAL OF GINSENG RESEARCH(1)
- JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY(1)
- KSBB JOURNAL(1)
- MACROMOLECULAR RESEARCH(1)
- THE JOURNAL OF MICROBIOLOGY(1)
- 대한치주과학회지(1)
- 미생물학회지(1)
- 미용산업연구(1)
- 발생과 생식(1)
- 산업미생물학회지(1)
- 한국농화학회지(1)
- 한국보건기초의학회지(1)
- 한국양식학회지(1)
- 한국유가공기술과학회지(1)
전체 선택해제
총 367건 검색
본문검색 결과만 보기
-
Purification of a Trypsin Inhibitor from Cocculus hirsutus and Identification of Its Biological Activity
Bhattacharjee. Chumki, Manjunath. Nagenahalli Huchappa, Prasad. Doddananjappa Theertha 한국작물학회 Journal of crop science and biotechnology 8 Pages
한국작물학회 Journal of crop science and biotechnology 2009, Vol.12 No.4 248-255 (8 pages)
-
Effect of Cultivars, Cooking and Processing on the Trypsin Inhibitor Activity of Soybean
Felipe. Penelope, Yang. Yoon-Hyung, Lee. Jung-Hee, Sok. Dai-Eun, Kim. Hyoung-Chin, Yoon. Won-Kee, Kim. Hwan-Mook, Kim. Mee-Ree 한국식품영양과학회 Journal of food science and nutrition 5 Pages
한국식품영양과학회 Journal of food science and nutrition 2005, Vol.10 No.1 6-10 (5 pages)
-
Combinational Effect of Moist Heating and Gamma Irradiation on The Inactivation of Trypsin Inhibitory Activity in Soybean
Felipe. Penelope, Yang. Yun-Hyoung, Lee. Jeong-Hee, Sok. Dai-Eun, Kim. Hyoung-Chin, Yoon. Won-Kee, Kim. Hwan-Mook, Kim. Mee-Ree 한국식품과학회 Food science and biotechnology 6 Pages
한국식품과학회 Food science and biotechnology 2005, Vol.14 No.6 732-737 (6 pages)
-
Streptomyces griseus Trypsin (SGT) Has Gelatinase Activity and Its Proteolytic Activity Is Enhanced by Manganese
Chi. Won-Jae, Kim. Yoon-Hee, Kim. Jong-Hee, Kang. Dae-Kyung, Kang. Sang-Soon, Suh. Joo-Won, Hong. Soon-Kwang 한국미생물학회 The journal of microbiology 6 Pages
한국미생물학회 The journal of microbiology 2003, Vol.41 No.4 289-294 (6 pages)
-
치주낭 탐침깊이와 치은연하치태내 Trypsin-like activity와의 관계
박재한, 한경윤, Park. Jea-Han, Han. Kyung-Yoon 대한치주과학회 대한치주과학회지 12 Pages
대한치주과학회 대한치주과학회지 1993, Vol.23 No.3 442-453 (12 pages)
-
Effect of oleanolic acid on the activity, secretion and gene expression of matrix metalloproteinase-3 in articular chondrocytes in vitro and the production of matrix metalloproteinase-3 in vivo
Dong-GeunKang, HyunJaeLee, KunTaeKim, Sun-ChulHwang, ChoongJaeLee, JinSungPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.2 7 197-204 (8 pages)
on IL-1β-induced secretion and proteolytic activity of MMP-3 were investigated using western blot analysis and casein zymography, respectively. The effect of oleanolic acid on in vivo MMP-3 protein production was also examined, after intra-articular injection to the knee joint of rat. The results were as follows: (1) oleanolic acid inhibited the gene expression of MMP-3, MMP-1, MMP-13, ADAMTS-4, and ADAMTS-5, but increased the gene expression of type II collagen; (2) oleanolic acid reduced the... -
4-(Tert-butyl)-2,6-bis(1-phenylethyl)phenol induces pro-apoptotic activity
JunHoKim, YunmiLee, Mi-YeonKim, JaeYoulCho 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.3 4 253-259 (7 pages)
(Cb-BF) displayed anti-cancer activity. To improve its anti-proliferative activity and production yield, we employed a total synthetic approach and derivatized KTH-13 to obtain chemical analogs. In this study, one KTH-13 derivative, 4-(tert-butyl)-2,6-bis(1-phenylethyl)phenol (KTH-13-t-Bu), was selected to test its anti-cancer activity. KTH-13-t-Bu diminished the proliferation of C6 glioma, MDA-MB-231, LoVo, and HCT-15 cells. KTH-13-t-Bu induced morphological changes in C6 glioma cells in a... -
Suppression of Peripheral Sympathetic Activity Underlies Protease-Activated Receptor 2-Mediated Hypotension
Young-HwanKim, Duck-SunAhn, Ji-HyunJoeng, SeungsooChung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.6 7 489-496 (8 pages)
completely occluded the suppression of EFS-evoked contraction by PAR-2 agonists. Finally, PAR-2 agonists suppressed the EFS-evoked overflow of NA in endothelium-denuded rat superior mesenteric arterial strips and this suppression was nearly completely occluded by ω-CgTx. These results suggest that activation of PAR-2 may suppress peripheral sympathetic outflow by modulating activity of ICa-N which are located in peripheral sympathetic nerve terminals, which results in PAR-2-induced hypotension. -
Effects of Lubiprostone on Pacemaker Activity of Interstitial Cells of Cajal from the Mouse Colon
Han-YiJiao, DongHyunKim, JungSukKi, KwonHoRyu, SeokChoi, JaeYeoulJun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.4 9 341-346 (6 pages)
cells of Cajal (ICCs) are pacemaker cells that generate slow-wave activity in smooth muscles. We studied the effects of lubiprostone on the pacemaker potentials of colonic ICCs. We used the whole-cell patch-clamp technique to determine the pacemaker activity in cultured colonic ICCs obtained from mice. Lubiprostone hyperpolarized the membrane and inhibited the generation of pacemaker potentials. Prostanoid EP1, EP2, EP3, and EP4 antagonists (SC-19220, PF-04418948, 6-methoxypyridine-2-boronc acid... -
Spontaneous Electrical Activity of Cultured Interstitial Cells of Cajal from Mouse Urinary Bladder
Sun-OuckKim, Han-SeongJeong, SujeongJang, Mei-JinWu, JongKyuPark, Han-YiJiao, JaeYeoulJun, Jong-SeongPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.6 9 531-536 (6 pages)
Interstitial cells of Cajal (ICCs) from the urinary bladder regulate detrusor smooth muscle activities. We cultured ICCs from the urinary bladder of mice and performed patch clamp and intracellular Ca2+ ([Ca2+]i) imaging to investigate whether cultured ICCs can be a valuable tool for cellular functional studies. The cultured ICCs displayed two types of spontaneous electrical activities which are similar to those recorded in intact bladder tissues. Spontaneous electrical activities of cultured... -
Activation of the cGMP/Protein Kinase G Pathway by Nitric Oxide Can Decrease TRPV1 Activity in Cultured Rat Dorsal Root Ganglion Neurons
YunjuJin, JunKim, JiyeonKwak 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.3 10 211-217 (7 pages)
G (PKG) pathway and the direct modification of proteins. Thus, in the present study, we investigated whether NO could indirectly modulate the activity of TRPV1 via a cGMP/PKG-dependent pathway in cultured rat dorsal root ganglion (DRG) neurons. NO donors, sodium nitroprusside (SNP) and S-nitro-N-acetylpenicillamine (SNAP), decreased capsaicin-evoked currents (Icap). NO scavengers, hemoglobin and 2-(4-carboxyphenyl)- 4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide (CPTIO), prevented the inhibitory... -
5-Hydroxytryptamine Generates Tonic Inward Currents on Pacemaker Activity of Interstitial Cells of Cajal from Mouse Small Intestine
PawanKumarShahi, SeokChoi, DongChuanZuo, CheolHoYeum, PyungJinYoon, JunLee, YoungDaeKim, ChanGukPark, ManYooKim, HyeRangShin, HyunJungOh, J 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.3 2 129-135 (7 pages)
the 5-HT-induced action on pacemaker activity, but not SB 204741 (a 5-HT2B receptor antagonist). Based on [Ca2＋]i analysis, we found that 5-HT increased the intensity of [Ca2＋]i. The treatment of PD 98059 or JNK II inhibitor blocked the 5-HT-induced action on pacemaker activity of ICC, but not SB 203580. In summary, these results suggest that 5-HT can modulate pacemaker activity through 5-HT3, 4, and 7 receptors via [Ca2＋]i mobilization and regulation of mitogen-activated protein kinases. -
The Inhibitory Effects of Hydrogen Sulfide on Pacemaker Activity of Interstitial Cells of Cajal from Mouse Small Intestine
ShankarPrasadParajuli, SeokChoi, JunLee, YoungDaeKim, ChanGukPark, ManYooKim, HyunIlKim, CheolHoYeum, JaeYeoulJun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.2 4 83-89 (7 pages)
of interstitial cells of Cajal (ICC), in the small intestine of mice. The actions of H2S on pacemaker activity were investigated using whole-cell patch-clamp technique, intracellular Ca2＋ analysis at 30oC and RT-PCR in cultured mouse intestinal ICC. Exogenously applied sodium hydrogen sulfide (NaHS), a donor of hydrogen sulfide, caused a slight tonic inward current on pacemaker activity in ICC at low concentrations (50 and 100</SUP>ՌM), but at high concentration (500ՌM and 1... -
Cytotoxic Activity and Three-Dimensional Quantitative Structure Activity Relationship of 2-Aryl-1,8-naphthyridin-4-ones
YongJinKim, EunAeKim, MiLyangChung, ChaeukIm 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.6 16 511-516 (6 pages)
13 exhibited the most potent activity with IC50 values of 2.3 and 13.4</SUB>ՌM, respectively. Three-dimensional quantitative structure activity relationship (3D-QSAR) studies of comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) were performed. Predictive 3D-QSAR models were obtained with q2 values of 0.869 and 0.872 and r2ncv values of 0.983 and 0.993 for CoMFA and CoMSIA, respectively. These results demonstrate that CoMFA and... -
(? )-Epigallocatechin Gallate Inhibits the Pacemaker Activity of Interstitial Cells of Cajal of Mouse Small Intestine
KweonYoungKim, SooJinChoi, HyukJinJang, DongChuanZuo, PawanKumarShahi, ShankarPrasadParajuli, CheolHoYeum, PyungJinYoon, SeokChoi, JaeYeo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.3 4 111-116 (6 pages)
inhibitor, and ODQ, a guanylate cyclase inhibitor, did not inhibit the effects of EGCG. EGCG-induced effects on pacemaker currents were not inhibited by glibenclamide, an ATP-sensitive K＋ channel blocker and TEA, a Ca2＋-activated K＋ channel blocker. Also, we found that EGCG inhibited the spontaneous [Ca2＋]i oscillations in cultured ICC. In conclusion, EGCG inhibited the pacemaker activity of ICC and reduced [Ca2＋]i oscillations by cAMP-, cGMP-, ATP-sensitive K+ channel-independent manner. -
Involvement of Thromboxane A2 in the Modulation of Pacemaker Activity of Interstitial Cells of Cajal of Mouse Intestine
JinHoKim, SooJinChoi, CheolHoYeum, PyungJinYoon, SeokChoi, JaeYeoulJun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.1 4 25-30 (6 pages)
Although many studies show that thromboxane A2 (TXA2) has the action of gastrointestinal (GI) motility using GI muscle cells and tissue, there are no reports on the effects of TXA2 on interstitial cells of Cajal (ICC) that function as pacemaker cells in GI tract. So, we studied the modulation of pacemaker activities by TXA2 in ICC with whole cell patch-clamp technique. Externally applied TXA2 (5ՌM) produced membrane depolarization in current-clamp mode and increased tonic inward pacemaker... -
Effects of (-)-Epigallocatechin-3-gallate on Brain Infarction and the Activity Change of Matrix Metalloproteinase-9 Induced by Middle Cerebral Artery Occlusion in Mice
YongRiQian, JiHyunKook, ShinaeHwang, DoKyungKim, Jong-KeunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.3 2 85-88 (4 pages)
a potent free radical scavenger and reduces the neuronal damage caused by oxygen free radicals. And it has been known that EGCG could reduce the infarction volume in focal brain ischemia and inhibit MMP-9 activity. To delineate the relationship between the anti-ischemic action and the MMP-9-inhibiting action of EGCG, we investigated the effect of EGCG on brain infarction and the activity of matrix metalloproteinase-9 induced by permanent middle cerebral artery occlusion (pMCAO) in ICR mice. EGCG... -
Inhibition of Pacemaker Activity of Interstitial Cells of Cajal by Hydrogen Peroxide via Activating ATP-sensitive K+ Channels
SeokChoi, ShankarPrasadParajuli, HyeonSookCheong, DilliParasadPaudyal, CheolHoYeum, PyungJinYoon, JaeYeoulJun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.1 3 15-20 (6 pages)
To investigate whether hydrogen peroxide (H2O2) affects intestinal motility, pacemaker currents and membrane potential were recorded in cultured interstitial cells of Cajal (ICC) from murine small intestine by using a whole-cell patch clamp. In whole cell patch technique at 30oC, ICC generated spontaneous pacemaker potential under current clamp mode (I=0) and inward currents (pacemaker currents) under voltage clamp mode at a holding potential of 70 mV. When ICC were treated with H2O2 in... -
pH-mediated Regulation of Pacemaker Activity in Cultured Interstitial Cells of Cajal
ByungJooKim, JaeHwaLee, InsukSo, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.1 2 7-12 (6 pages)
pacemaker activity in cultured interstitial cells of Cajal. Under voltage clamp mode and at the holding potential of 60 mV, the I-V relationships and difference current showed that there was no reversal potential and voltage-independent inward current. Also, when the holding potentials were changed from 20 mV to 80 mV with intervals of 20 mV, there was little difference in inward current. In pacemaker activity, the resting membrane potential (RMP) was depolarized (In pH 5.5,...
