주제분류
- 의약학(301)
- 농수해양학(105)
- 교육학(73)
- 자연과학(44)
- 보건학(14)
- 기타(12)
- 사회과학(7)
- 인문학(5)
- 특수교육학(4)
- 심리학(2)
- 유아교육학(2)
- 공학(1)
- 사회복지학(1)
- 예체능(1)
- 종교(1)
자료유형
발행기관
- 대한생리학회-대한약리학회(189)
- 대한수의학회(105)
- 대한신경정신의학회(58)
- 우리말학회(55)
- 한국탄소학회(32)
- 대한생리학회(27)
- 대한약리학회(15)
- 한국기초간호학회(11)
- 한국식물병리학회(8)
- 한국일본교육학회(6)
- 대한방사선방어학회(5)
- 인문사회과학기술융합학회(5)
- 물리치료재활과학회(4)
- 한국박물관학회(4)
- 한국습지학회(4)
- 한국의학교육학회(4)
- 한국교육행정학회(3)
- 대한치과이식임플란트학회(2)
- 한국교육개발원(2)
- 한국응용생명화학회(2)
- 한국학습장애학회(2)
- 한방비만학회(2)
- 경인교육대학교 교육연구원(1)
- 국민연금연구원(1)
- 대한방사선종양학회(1)
- 대한핵의학회(1)
- 아시아장애사회학회(1)
- 은행법학회(1)
- 이화여자대학교 교과교육연구소(1)
- 한국교원교육학회(1)
- 한국교육방법학회(1)
- 한국기업교육학회(1)
- 한국노인간호학회(1)
- 한국농촌간호학회(1)
- 한국대학박물관협회(1)
- 한국미술치료학회(1)
- 한국보건기초의학회(1)
- 한국불교상담학회(1)
- 한국사회과수업학회(1)
- 한국상담평가학회(1)
- 한국식품영양학회(1)
- 한국아동권리학회(1)
- 한국열환경공학회(1)
- 한국웰니스학회(1)
- 한국정보처리학회(1)
- 한국조형교육학회(1)
- 한국청각언어재활학회(1)
- 한국특수교육교과교육학회(1)
- 한국환경농학회(1)
- 환태평양유아교육연구학회(1)
간행물
- THE KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY(189)
- JOURNAL OF VETERINARY SCIENCE(78)
- 신경정신의학(58)
- 우리말연구(55)
- CARBON LETTERS(32)
- 대한생리학회지(27)
- KOREAN JOURNAL OF VETERINARY RESEARCH(구 대한수의학회지)(22)
- 대한약리학잡지(15)
- JOURNAL OF KOREAN BIOLOGICAL NURSING SCIENCE(11)
- THE PLANT PATHOLOGY JOURNAL (8)
- 대한수의학회 학술대회발표집(5)
- 방사선방어학회지(5)
- 예술인문사회융합멀티미디어논문지(5)
- KOREAN JOURNAL OF MEDICAL EDUCATION(4)
- PHYSICAL THERAPY REHABILITATION SCIENCE(4)
- 박물관학보(4)
- 한국습지학회지(4)
- 한국일본교육학연구(4)
- 교육행정학연구(3)
- JOURNAL OF DENTAL IMPLANT RESEARCH(2)
- 대한한방비만학회지(2)
- 한국교육개발원 연구보고서(2)
- 한국농화학회지(2)
- 한국일본교육학회 학술대회(2)
- AUDIOLOGY AND SPEECH RESEARCH(1)
- PACIFIC EARLY CHILDHOOD EDUCATION RESEARCH ASSOCIATION ANNUAL CONFERENCE(1)
- 고문화(1)
- 교과교육학연구(1)
- 교육논총(1)
- 교육방법연구(1)
- 국민연금연구원 연구보고서(1)
- 노인간호학회지(1)
- 대한치료방사선과학회지(1)
- 대한핵의학회지(1)
- 미술치료연구(1)
- 불교상담학연구(1)
- 사회과수업연구(1)
- 상담평가연구(1)
- 아동과 권리(1)
- 아시아장애사회학연구(1)
- 열환경공학(1)
- 은행법연구(1)
- 정보처리학회논문지. THE KIPS TRANSACTIONS. PART D. PART D(1)
- 조형교육(1)
- 특수교육교과교육연구(1)
- 학습장애연구(1)
- 한국HRD연합회 연합학술대회지(1)
- 한국교원교육연구(1)
- 한국농촌간호학회 학술대회지(1)
- 한국보건기초의학회지(1)
- 한국식품영양학회지(1)
- 한국웰니스학회지(1)
- 한국학습장애학회 학술대회지(1)
- 한국환경농학회지(1)
전체 선택해제
총 573건 검색
본문검색 결과만 보기
-
Bacillus sp. CS-17로 제조한 청국장 발효기간별 품질변화
손동화, 권오진, 지원대, 최웅규, 권오준, 이은정, 조영제, 차원섭, 정영건, Son. Dong-Hwa, Kwon. Oh-Jin, Ji. Won-Dae, Choi. Ung-Kyu, Kwon. O-Jun, Lee. Eun-Joung, Cho. Young-J 한국응용생명화학회 한국농화학회지 6 Pages
한국응용생명화학회 한국농화학회지 2000, Vol.43 No.1 1-6 (6 pages)
Bacillus sp. CS-17를 이용하여 청국장을 제조한 후 발효기간별 특성을 조사하였다. pH는 발효가 진행됨에 따라 점차 알카리화하였다. 색도를 조사한 결과 명도는 숙성이 지속될수록 낮아졌으며, 황색도는 약간 증가 하였다. 적색도는 차이가 없었다. 지용성 갈변물질은 거의 생성되지 않았으며, 수용성 갈현물질은 많은 양이 생성되었다. 강도와 경도는 발효초기부터 급격히 감소하였다. 아미노산 총 함량은 $8274.7{sim}9301.4;mg%$이었고 phenylalanine, lysine, leucine, tyrosine이 많이 함유되어 있었다. 총 필수아미노산의 함량은... -
Bacillus sp. CS-17의 색소 생성조건 및 색소 농축액의 항균특성
손동화, 권오진, 최웅규, 정영건, Son. Dong-Hwa, Kwon. Oh-Jin, Choi. Ung-Kyu, Chung. Yung-Gun 한국응용생명화학회 한국농화학회지 6 Pages
한국응용생명화학회 한국농화학회지 1998, Vol.41 No.3 213-218 (6 pages)
첨가한 색소 생성용 기본배지에서 가장 높은 색소 생성능을 가지는 것으로 나타났다. 배양조건이 Bacillus sp. CS-17의 색소 생성에 미치는 효과를 조사한 결과, pH 8.5에서 $37^{circ}C$, 72시간 배양하였을 때 최적의 색소 생성을 보였다. NaCl의 첨가는 색소 생성능을 억제하는 것으로 나타났다. 이상의 결과로 Bacillus sp. CS-17의 색소 생성 최적조건은 $37^{circ}C$, pH 8.5에서 72시간동안 배양하였을 때로 추정되었다. 그람 양성균 5주 및 그람 음성균 6주에 대하여 색소 농축액의 항균활성을 paper disc법으로 조사한 결과, B.... -
Cs-137 및 Co-60감마선 조사장치 설치 연구
김원식, 하석호, 황선태, Kim. Wuon-Shik, Hah. Suck-Ho, Hwang. Sun-Tae 대한방사선방어학회 방사선방어학회지 7 Pages
대한방사선방어학회 방사선방어학회지 1986, Vol.11 No.2 123-129 (7 pages)
Cs-137 및 Co-60감마선 조사장치를 사용하여 비임의 입체각이 $2.4{pi}{ imes}10^{-3}sr$에서 $17.3{pi}{ imes}10^{-3}sr$로 변함에 따른 공기의 산란인자와 두께 2.9cm 납 흡수체 사용에 따른 축적인자를 결정하였다. 그 결과 산란인자는 $1{sim}1.064$, 축적인자는 $1.054{sim}1.194$범위의 값을 갖는 것으로 각각 나타났다. 결정된 인자들의 검증을 위하여 계산값과 측정값을 비교한 결과 그 차이는 3.3%이하인 것으로 나타났다. -
아동·청소년복지 종사자의 공감만족과 공감피로(CS-CF)에 미치는 영향요인 연구
박지선, 천지은 인문사회과학기술융합학회 예술인문사회융합멀티미디어논문지 8 Pages
인문사회과학기술융합학회 예술인문사회융합멀티미디어논문지 2016, 제 6권 제 10호 34 355-363 (8 pages)
-
한국의 논과 밭에서 $^{137}Cs$ 의 토양-작물체 전이계수
최용호, 임광묵, 이명호, 최근식, 정규회, Choi. Yong-Ho, Lim. Kwang-Muk, Lee. Myung-Ho, Choi. Geun-Sik, Chung. Kyu-Hoi 한국환경농학회 한국환경농학회지 5 Pages
한국환경농학회 한국환경농학회지 1999, Vol.18 No.2 164-168 (5 pages)
우리나라 농경지에서의 토양-작물체간 $^{137}Cs$ 전이계수를 조사하기 위하여 전국 33지역의 논과 밭에서 벼와 배추의 수확기에 작물과 표층토를 채취하고 ${gamma}$-스펙트로메트리법으로 $^{137}Cs$ 농도를 측정하였다. 경작지 토양중 $^{(137)}Cs$의 농도는 논에서는 $0.7{sim}17.7$ Bq/kg-dry, 밭에서는 $1.2{sim}27.8$ Bq/kg-dry의 범위로 평균은 각각 6.9Bq/kg-dry 및 9.9Bq/kg-dry였다. 현미 및 배추내 $^{(137)}Cs$의 농도는 각각 12 지역에서만 측정되었는데 현미의 경우 0.019$0.019{sim}0.111$ Bq/kg-dry의 범위로 평균... -
Effects of 3-dimensional balance trainer in combination with a video-game system on balance and gait ability in subacute stroke patients
Hyun Geun Ha, Young Jun Ko, Hwang Jae Lee, Wan Hee Lee 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2014, 제 3권 제 1호 2 7-12 (6 pages)
Objective: The purpose of this study was to investigate the effects of a three dimensional balance trainer in combination with a video-game system and visual feedback on balance recovery and gait function in subacute stroke patients. Design: Randomized controlled trial. Methods: Twenty-three subacute stroke patients were assigned to either an experimental (n=12) or a control group (n=11) using a random permuted block design and sealed envelopes. The experimental group received additional... -
International Collaborative Faculty Development Program on Simulation-Based Healthcare Education: A Report on Its Successes and Challenges
Hyun Soo Chung, S. Barry Issenberg, Paul Phrampus, Geoff Miller, Sang Mo Je, Tae Ho Lim, Young Min Kim 한국의학교육학회 Korean Journal of Medical Education 9 Pages
한국의학교육학회 Korean Journal of Medical Education 2012, 제 24권 제 4호 6 319-327 (9 pages)
-
Genetic Characterization of Salmonella Enteritidis and Salmonella Typhimurium Isolated from Samples of Slaughtered Animals during 2003-2008 in Korea
Sia Kang, Heui Jin Kim, Suk Kyung Lim, Kichan Lee, Dong Chan Moon, Hee Soo Lee, Hyang Mi Nam 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 춘계학술심포지움 96 188-189 (2 pages)
-
Aminoglycoside Modifying Enzymes (AMEs) occurrence among Isolates of Escherichia coli exhibiting High-Level of Aminoglycoside Resistance Isolated from Korean Cattle Farms
Kuastros Mekonnen Belaynehe, Seung Won Shin, Hong Tae Park, Han Sang Yoo 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 197 299-300 (2 pages)
-
An enhanced immunochromatographic strip test using colloidal gold nanoparticle-labeled dual-type N proteins for detection of antibodies to PRRS virus
Ji Eun Yu, In-Ohk Ouh, Hyeonjeong Kang, Hye-young Lee, Kwang-Myun Cheong, In-Soo Cho, Sang-Ho Cha 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 4호 7 519-527 (9 pages)
Porcine reproductive and respiratory syndrome (PRRS) is recognized as one of the most important infectious diseases causing serious economic loss in the swine industry worldwide. Due to its increasing genetic diversity, a rapid and accurate diagnosis is critical for PRRS control. The immunochromatographic strip test (ICST) is a rapid and convenient type of immunoassay. In this study, an on-site immunochromatographic assay-based diagnostic method was developed for detection of PRRS virus... -
Comparison of electrophysiological properties of two types of pre-sympathetic neurons intermingled in the hypothalamic paraventricular nucleus
Yiming Shen, Seong Kyu Han, Pan Dong Ryu 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 4호 2 483-491 (9 pages)
The hypothalamic paraventricular nucleus (PVN) contains two types of neurons projecting to either the rostral ventrolateral medulla (PVNRVLM) or the intermediolateral horn (IML) of the spinal cord (PVNIML). These two neuron groups are intermingled in the same subdivisions of the PVN and differentially regulate sympathetic outflow. However, electrophysiological evidence supporting such functional differences is largely lacking. Herein, we compared the electrophysiological properties of these... -
Production of transgenic pigs using a pGFAP-CreERT2/EGFP LoxP inducible system for central nervous system disease models
Seon-Ung Hwang, Kiyoung Eun, Junchul David Yoon, Hyunggee Kim, Sang-Hwan Hyun 대한수의학회 Journal of Veterinary Science 12 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 3호 13 434-445 (12 pages)
Transgenic (TG) pigs are important in biomedical research and are used in disease modeling, pharmaceutical toxicity testing, and regenerative medicine. In this study, we constructed two vector systems by using the promoter of the pig glial fibrillary acidic protein (pGFAP) gene, which is an astrocyte cell marker. We established donor TG fibroblasts with pGFAP-CreERT2/LCMV-EGFPLoxP and evaluated the effect of the transgenes on TG-somatic cell nuclear transfer (SCNT) embryo development. Cleavage... -
Comparison of the effects of isoflurane versus propofolremifentanil anesthesia on oxygen delivery during thoracoscopic lung lobectomy with one-lung ventilation in dogs
Jiyoung Park, Hae-Beom Lee, Seong Mok Jeong 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 3호 12 426-433 (8 pages)
This study compared effects of isoflurane inhalation (ISO) and propofol-remifentanil combined total intravenous anesthesia (TIVA) on oxygenation during thoracoscopic lung lobectomy with 30-min one-lung ventilation (1LV). Thoracoscopic right middle lung lobectomy was performed in ten dogs divided into ISO and TIVA groups, and cardiopulmonary parameters were measured with blood gas analysis. Throughout the study, isoflurane was inhaled up to 1.5%, and the infusion rates of propofol and... -
Tibial dyschondroplasia is closely related to suppression of expression of hypoxia-inducible factors 1α, 2α, and 3α in chickens
Shucheng Huang, Mujeeb U. Rehman, Gang Qiu, Houqiang Luo, Muhammad K. Iqbal, Hui Zhang, Khalid Mehmood, Jiakui Li 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 1호 14 107-115 (9 pages)
Tibial dyschondroplasia (TD) cases has not been reported in Tibetan chickens (TBCs), but it is commonly seen in commercial broilers characterized by lameness. The underlying mechanism remains unclear. Hypoxia-inducible factors (HIFs) are important regulators of cellular adaptation to hypoxic conditions. In this study, we investigated the role of HIF-1α, -2α, and -3α in hypoxia and thiram-induced TD and their effect on tibial growth plate development in Arbor Acres chickens (AACs) and TBCs.... -
Comparison of allele-specific PCR, created restriction-site PCR, and PCR with primer-introduced restriction analysis methods used for screening complex vertebral malformation carriers in Holstein cattle
Kozet Avanus, Ahmet Altınel 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 4호 9 465-470 (6 pages)
Complex vertebral malformation (CVM) is an inherited, autosomal recessive disorder of Holstein cattle. The aim of this study was to compare sensitivity, specificity, positive and negative predictive values, accuracy, and rapidity of allele-specific polymerase chain reaction (AS-PCR), created restriction-site PCR (CRS-PCR), and PCR with primer-introduced restriction analysis (PCR-PIRA), three methods used in identification of CVM carriers in a Holstein cattle population. In order to screen for... -
Inhibitory effects of resveratrol on hepatitis B virus X protein-induced hepatocellular carcinoma
Seungmo Park, Jihae Lim, Jong Rhan Kim, Seongbeom Cho 대한수의학회 Journal of Veterinary Science 11 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 4호 1 419-429 (11 pages)
Liver cancer occurs very frequently worldwide and hepatocellular carcinoma (HCC) accounts for more than 80% of total primary liver cancer cases. In this study, the anticarcinogenic effects of resveratrol against hepatitis B virus (HBV)-induced HCC were investigated by using HBV X-protein-overexpressing Huh7 (Huh7-HBx) human hepatoma cells. MTT assay showed that resveratrol decreased cell viability. Fluorescence-activated cell-sorter analysis showed that resveratrol induced G1 cell cycle arrest... -
Sequence analysis of the spike gene of Porcine epidemic diarrhea virus isolated from South China during 2011-2015
Xiaoya Zhao, Zhili Li, Xiduo Zeng, Guanqun Zhang, Jianqiang Niu, Baoli Sun, Jingyun Ma 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 2호 14 237-243 (7 pages)
The spike gene of porcine epidemic diarrhea virus (PEDV) was sequenced from 55 South China field strains isolated from pigs with symptoms of diarrhea. The sequences were compared within the set of field strains as well as with reference strains available in GenBank. Within the 55 South China PEDV field strains, the deduced amino acid sequence identities ranged from 93.8% to 99.9 % and ranged from 90.7% to 99.5% when compared with the foreign reference strains in GenBank. Our phylogenetic... -
A serological study of severe fever with thrombocytopenia syndrome using a virus neutralization test and competitive enzyme-linked immunosorbent assay
Hyojin Lee, Eun-Ju Kim, In-Soo Cho, Jae-Young Song, Jeong Soo Choi, Ji Youn Lee, Yeun-Kyung Shin 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 1호 5 33-38 (6 pages)
Severe fever with thrombocytopenia syndrome (SFTS) is caused by the SFTS virus (SFTSV). The SFTSV appears to have a wide host range, as SFTSV-positive ticks have been isolated from both farm animals and wild rodents. Therefore, it is important to monitor SFTSV-positive animals to prevent the transmission of SFTSV from animals to humans. Previously, we developed a competitive enzyme-linked immunosorbent assay (cELISA) to detect SFTSV-specific antibodies from field animals and compared the cELISA... -
Effects of gonadotropin-releasing hormone administration or a controlled internal drug-releasing insert after timed artificial insemination on pregnancy rates of dairy cows
Jae Kwan Jeong, In Soo Choi, Hyun Gu Kang, Tai Young Hur, Ill Hwa Kim 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 4호 18 577-582 (6 pages)
This study investigated the effects of gonadotrophin-releasing hormone (GnRH) administration (Experiment 1) and a controlled internal drug-releasing (CIDR) insert (Experiment 2) after timed artificial insemination (TAI) on the pregnancy rates of dairy cows. In Experiment 1, 569 dairy cows that underwent TAI (day 0) following short-term synchronization with prostaglandin F2α were randomly allocated into two groups: no further treatment (control, n = 307) or injection of 100 μg of gonadorelin on... -
Canine adipose tissue-derived mesenchymal stem cells ameliorate severe acute pancreatitis by regulating T cells in rats
Hyun-Wook Kim, Woo-Jin Song, Qiang Li, Sei-Myoung Han, Kee-Ok Jeon, Sang-Chul Park, Min-Ok Ryu, Hyung-Kyu Chae, Kweon Kyeong, Hw 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 4호 13 539-548 (10 pages)
Severe acute pancreatitis (SAP) is associated with systemic complications and high mortality rate in dogs. Mesenchymal stem cells (MSCs) have been investigated for their therapeutic potential in several inflammation models. In the present study, the effects of canine adipose tissue-derived (cAT)-MSCs in a rat model of SAP induced by retrograde injection of 3% sodium taurocholate solution into the pancreatic duct were investigated. cAT-MSCs labeled with... -
Matrix-assisted laser desorption ionization-time of flight mass spectrometry based identification of Edwardsiella ictaluri isolated from Vietnamese striped catfish (Pangasius hypothalamus)
Truong Quynh Nhu, Seong Bin Park, Si Won Kim, Jung Seok Lee, Se Pyeong Im, Jassy Mary S. Lazarte, Jong Pyo Seo, Woo-Jai Lee, Jae 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 3호 15 377-383 (7 pages)
Edwardsiella (E.) ictaluri is a major bacterial pathogen that affects commercially farmed striped catfish (Pangasius hypothalamus) in Vietnam. In a previous study, 19 strains of E.ictaluri collected from striped catfish were biochemically identified with an API-20E system. Here, the same 19 strains were used to assess the ability of matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS; applied using a MALDI Biotyper) to conduct rapid, easy and accurate... -
Expression of neurotrophic factors in injured spinal cord after transplantation of human-umbilical cord blood stem cells in rats
Hyo-jin Chung, Wook-hun Chung, Jae-Hoon Lee, Dai-Jung Chung, Wo-Jong Yang, A-Jin Lee, Chi-Bong Choi, Hwa-Seok Chang, Dae-Hyun Ki 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 1호 12 97-102 (6 pages)
We induced percutaneous spinal cord injuries (SCI) using a balloon catheter in 45 rats and transplanted human umbilical cord blood derived mesenchymal stem cells (hUCB-MSCs) at the injury site. Locomotor function was significantly improved in hUCB-MSCs transplanted groups. Quantitative ELISA of extract from entire injured spinal cord showed increased expression of brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF) and neurotrophin-3 (NT-3). Our results show that treatment of SCI... -
Effect of autologous platelet-rich plasma application on cutaneous wound healing in dogs
Cho-Hee Jee, Na-Young Eom, Hyo-Mi Jang, Hae-Won Jung, Eul-Soo Choi, Jin-Hee Won, Il-Hwa Hong, Byeong-Teck Kang, Dong Wook Jeong, 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 1호 10 79-87 (9 pages)
This study was conducted to identify the effectiveness of platelet-rich plasma (PRP) and efficacy of intralesional injection as a method of application to acute cutaneous wounds in dogs. Healthy adult beagles (n = 3) were used in this study. Autologous PRP was separated from anticoagulant treated whole blood in three dogs. Cutaneous wounds were created and then treated by intralesional injection of PRP in the experimental group, while they were treated with saline in the control group on days 0,... -
Time-course changes in the expression levels of miR-122, -155, and -21 as markers of liver cell damage, inflammation, and regeneration in acetaminophen-induced liver injury in rats
Hyun-Kyu Park, Woori Jo, Hyun-Ji Choi, Sungwoong Jang, Jae-Eun Ryu, Hyo-Ju Lee, Hyojin Lee, Hyejin Kim, Eun-Sil Yu, Woo-Chan Son 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 1호 6 45-51 (7 pages)
Drug-induced liver injury (DILI) is a significant threat to patient health and a major concern during drug development. Recently, multiple circulating microRNAs (miRNAs) have been reported to be potential biomarkers for DILI. To adapt and validate miRNAs for clinical use, we investigated the time-course changes in miR-122 expression levels in an acetaminophen-induced liver injury model in rats. In addition, miR-155 and miR-21 were evaluated as makers of inflammation and regeneration,... -
A multiplex quantitative real-time polymerase chain reaction panel for detecting neurologic pathogens in dogs with meningoencephalitis
Jae-Ik Han, Dong-Woo Chang, Ki-Jeong Na 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 3호 12 341-347 (7 pages)
Meningoencephalitis (ME) is a common inflammatory disorder of the central nervous system in dogs. Clinically, ME has both infectious and non-infectious causes. In the present study, a multiplex quantitative real-time polymerase chain reaction (mqPCR) panel was optimized for the detection of eight canine neurologic pathogens (Blastomyces dermatitidis, Cryptococcus spp., Neospora caninum, Borrelia burgdorferi, Bartonella spp., Toxoplasma gondii, Ehrlichia canis, and canine distemper virus [CDV]).... -
Comparison of pharmacological and genetic inhibition of cyclooxygenase-2: effects on adult neurogenesis in the hippocampal dentate gyrus
Sung Min Nam, Jong Whi Kim, Dae Young Yoo, Jung Hoon Choi, Woosuk Kim, Hyo Young Jung, Moo-Ho Won, In Koo Hwang, Je Kyung Seong, 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 3호 1 245-251 (7 pages)
Inducible cyclooxygenase-2 (COX-2) has received much attention because of its role in neuro-inflammation and synaptic plasticity. Even though COX-2 levels are high in healthy animals, the function of this factor in adult neurogenesis has not been clearly demonstrated. Therefore, we performed the present study to compare the effects of pharmacological and genetic inhibition of COX-2 on adult hippocampal neurogenesis. Physiological saline or the same volume containing celecoxib was administered... -
The potential role of COX-2 in cancer stem cell-mediated canine mammary tumor initiation: an immunohistochemical study
Jian Huang, Di Zhang, Fuqiang Xie, Degui Lin 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 2호 13 225-231 (7 pages)
Increasing evidence suggests that cancer stem cells (CSCs) are responsible for tumor initiation and maintenance. Additionally, it is becoming apparent that cyclooxygenase (COX) signaling is associated with canine mammary tumor development. The goals of the present study were to investigate COX-2 expression patterns and their effect on CSC-mediated tumor initiation in primary canine mammary tissues and tumorsphere models using immunohistochemistry. Patterns of COX-2, CD44, octamer-binding...
