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본문검색 결과만 보기
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Repair of ischemic injury by pluripotent stem cell derived endothelial cells without teratoma formation through selective photosensitivity
Seung Ju Cho, So Yeon Kim, Ho Chang Jeong, Hyung Min Chung, Sung Hwan Moon, Hyuk Jin Cha 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 춘계학술심포지움 11 83-83 (1 pages)
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Nafamostat Mesilate Inhibits TNF-α-Induced Vascular Endothelial Cell Dysfunction by Inhibiting Reactive Oxygen Species Production
Min-WoongKang, Hee-JungSong, ShinKwangKang, YonghwanKim, Saet-byelJung, SungjuJee, JaeYoungMoon, Kwang-sunSuh6, SangDoLee, ByeongHwaJeon, 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.3 6 229-234 (6 pages)
extracorporeal circulation in patients undergoing continuous renal replacement therapy and extra corporeal membrane oxygenation. Oxidative stress is an independent risk factor for atherosclerotic vascular disease and is associated with vascular endothelial function. We investigated whether NM could inhibit endothelial dysfunction induced by tumor necrosis factor-α (TNF-α). Human umbilical vein endothelial cells (HUVECs) were treated with TNF-α for 24 h. The effects of NM on monocyte adhesion,... -
Ginsenoside Rg2 Inhibits Lipopolysaccharide-Induced Adhesion Molecule Expression in Human Umbilical Vein Endothelial Cell
Young-SukCho, ChanHyungKim, Tae-SunHa, SangJinLee, HeeYulAhn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.2 4 133-137 (5 pages)
Vascular cell adhesion molecule 1 (VCAM-1), intercellular adhesion molecule 1 (ICAM-1), P- and E-selectin play a pivotal role for initiation of atherosclerosis. Ginsenoside, a class of steroid glycosides, is abundant in Panax ginseng root, which has been used for prevention of illness in Korea. In this study, we investigated the mechanism(s) by which ginsenoside Rg2 may inhibit VCAM-1 and ICAM-1 expressions stimulated with lipopolysaccharide (LPS) in human umbilical vein endothelial cell... -
Overexpression of Ref-1 Inhibits Lead-induced Endothelial Cell Death via the Upregulation of Catalase
KwonHoLee, SangKiLee, HyoShinKim, EunJungCho, HeeKyoungJoo, EunJiLee, JiYoungLee, MyoungSooPark, SeokJongChang, Chung-HyunCho, JinBongPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.6 4 431-436 (6 pages)
in a concentration- and time-dependent manner. However, Ref-1 overexpression with AdRef-1 significantly inhibited Pb-induced cell death in the endothelial cells. Also the overexpression of Ref-1 significantly suppressed Pb-induced superoxide and hydrogen peroxide elevation in the endothelial cells. Pb exposure induced the downregulation of catalase, it was inhibited by the Ref-1 overexpression in the endothelial cells. Taken together, our data suggests that the overexpression of Ref-1 inhibited... -
Heparin Attenuates the Expression of TNFα-induced Cerebral Endothelial Cell Adhesion Molecule
JeongHoLee, ChulHoonKim, GiHoSeo, JinuLee, JooHeeKim, DongGooKim, YoungSooAhn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.5 3 231-236 (6 pages)
on neuroinflammation-related diseases, such as Alzheimer's disease and meningitis. However, the underlying mechanism of its actions remains unclear. In the present study, we examined the anti-inflammatory mechanism of heparin in cultured cerebral endothelial cells (CECs), and found that heparin inhibited the tumor necrosis factor Ձ(TNFՁ)-induced and nuclear factor kappa B (NF-ՊB)-dependent expression of adhesion molecules, such as intercellular adhesion molecule-1 (ICAM-1) and... -
NADPH Oxidase and Mitochondrial ROS are Involved in the TNF-α-induced Vascular Cell Adhesion Molecule-1 and Monocyte Adhesion in Cultured Endothelial Cells
JaeHyeonYu, CukSeongKim, DaeGoonYoo, YunJeongSong, HeeKyoungJoo, GunKang, JiYoonJo, JinBongPark, ByeongHwaJeon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.4 9 217-221 (5 pages)
on the vascular cell adhesion molecule-1 (VCAM-1) and monocyte adhesion in the cultured endothelial cells. TNF-α at a range of 1~30 ng/ml induced VCAM-1 expression dose-dependently. BCECF-AM-labeled U937 cells firmly adhered on the surface of endothelial cells when the endothelial cells were incubated with TNF-α (15 ng/ml). Ten μmol/L of SB203580, an inhibitor of p38 MAPK, significantly reduced TNF-α-induced VCAM-1 expression, compared to the JNK inhibitor (40μmol/L of SP60015) or ERK... -
Vibrio vulnificus Cytolysin Forms Anion-selective Pores on the CPAE Cells, a Pulmonary Endothelial Cell Line
Bok-HeeChoi, Byung-HyunPark, Yong-GeunKwak 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.5 4 259-264 (6 pages)
a CPAE cell, a cell line of pulmonary endothelial cell, using inside-out patch clamp techniques. In symmetrical NaCl concentration (140 mM), intracellular or extracellular application of cytolysin formed ion-permeable pores with a single channel conductance of 37.5⁑4.0 pS. The pore currents were consistently maintained after washout of cytolysin. Replacement of Na in bath solution with monovalent ions (K, Cs or TEA) or with divalent ions (Mg2, Ca2)... -
Inhibition of NF-κB Activation Increases Oxygen-Glucose Deprivation-Induced Cerebral Endothelial Cell Death
JinuLee, ChulHoonKim, KyuDaeShim, YoungSooAhn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.2 3 65-71 (7 pages)
injury was investigated. OGD was found to activate NF-κB and to induce bEnd.3 cell death in a time-dependent manner. OGD phosphorylated neither 32 Ser nor 42 Tyr of IκBα. OGD did not change the amount of IκBα. The extents of OGD-induced cell death after 8 h, 10 h, 12 h and 14 h of OGD were 10%, 35%, 60% and 85%, respectively. Reperfusion following OGD did not cause additional cell death, indicating no reperfusion injury after ischemic insult in cerebral endothelial cells. Three known as... -
Role of Protein Kinases on NF-κB Activation and Cell Death in Bovine Cerebral Endothelial Cells
YoungSooAhn, ChulHoonKim, JooHeeKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.1 2 11-18 (8 pages)
Nuclear factor κB (NF-κB) activation is modulated by various protein kinases. Activation of NF-κB is known to be important in the regulation of cell viability. The present study investigated the effect of inhibitors of protein tyrosine kinase (PTK), protein kinase C (PKC) and protein kinase A (PKA) on NF-κB activity and the viability of bovine cerebral endothelial cells (BCECs). In serum-deprivation-induced BCEC death, low doses of TNFα showed a protective effect. TNFα induced NF-κB... -
Nitric Oxide Prevents the Bovine Cerebral Endothelial Cell Death Induced by Serum-Deprivation
ChulHoonKimYoungSooAhn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.5 6 515-521 (7 pages)
was partially blocked, suggesting that iNOS expression was involved in controlling cell death. Exogenously added NO substrate (L-arginine) and NO donors (sodium nitroprusside and S-nitroso-N-acetylpenicillamine) also inhibited the cell death induced by serum deprivation. These results suggest that NO has protective effect on bovine cerebral endothelial cell death induced by serum-deprivation and that iNOS is one of the possible target molecules by which NF-κB exerts its cytoprotective effect. -
Effects of Tubulyzines, Novel Microtubule-Binding Triazine Molecules, on Endothelial Progenitor Cell Differentiation
Park. Hyo-Eun, Lee. Soo-Young, Ahn. Hyun-Young, Shin. Jong-Cheol, Chang. Young-Tae, Joe. Young-Ae 한국응용약물학회 The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmaco 6 Pages
한국응용약물학회 The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmaco 2003, Vol.11 No.2 85-90 (6 pages)
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Identification of Plant Extracts that Inhibit Cellular Senescence in Human Fibroblasts, Endothelial Cells, and Vascular Smooth Muscle Cell
Yang. Hyo-Hyun, Jung. Bo-Chan, Kim. Jae-Ryong 한국응용생명화학회 Journal of the Korean Society for Applied Biological Chemistry 9 Pages
한국응용생명화학회 Journal of the Korean Society for Applied Biological Chemistry 2010, Vol.53 No.5 584-592 (9 pages)
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A standardized bamboo leaf extract inhibits monocyte adhesion to endothelial cells by modulating vascular cell adhesion protein-1
Choi. Sunga, Park. Myoung Soo, Lee. Yu Ran, Lee. Young Chul, Kim. Tae Woo, Do. Seon-Gil, Kim. Dong Seon, Jeon. Byeong Hwa 한국영양학회 Nutrition research and practice 6 Pages
한국영양학회 Nutrition research and practice 2013, Vol.7 No.1 9-14 (6 pages)
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Comparison of the Adhesion and Proliferation Characteristics of HUVEC and Two Endothelial Cell Lines (CRL 2922 and CRL 2873) on Various Substrata
Heng. Boon-Chin, Xia. Yun, Shang. Xiaobo, Preiser. Peter Rainer, Law. S.K. Alex, Boey. Freddy Yin-Chiang, Venkatraman. Subbu S. 한국생물공학회 Biotechnology and bioprocess engineering 9 Pages
한국생물공학회 Biotechnology and bioprocess engineering 2011, Vol.16 No.1 127-135 (9 pages)
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4-Hydroxynonenal Induces Endothelial Cell Apoptosis via ROS and Peroxynitrite Generation
정상운, 이수복, 이지영, 호세인 모하메드 악바르, 김동환, 장정윤, 윤정현, 정해영, 김남득, Chung. Sang-Woon, Yee. Su-Bog, Lee. Ji-Young, Hossain. Mohammad Akbar, Kim. Dong-Hwan, Y 한국생명과학회 생명과학회지 8 Pages
한국생명과학회 생명과학회지 2011, Vol.21 No.7 961-968 (8 pages)
지질과산화로부터 생성된 aldehyde 중 4-hydroxynonenal (HNE)는 산화적 손상과 관련된 다량의 arachidonic acids, linoleic acids 등으로부터 생성될 수 있다. 그러므로 HNE는 산화적 스트레스와 관련된 세포사에서 중요한 매개인자로 작용을 할 수가 있을 것이다. 본 연구는 HNE가 세포사를 유발할 것이라 가정하고, 먼저 흰쥐 전립선 유래 내피세포인 YPEN-1 세포에서 세포독성을 측정하였다. 세포생장 저해능력은 HNE를 $5sim15;{mu}M$ 농도로 처리하여 형태적 변화와 MTT assay를 통하여 결과를 관찰하였다. 그 결과 HNE가 이... -
Protection Effects of Allylmercaptan, Metabolite of Garlic on Endothelial Cell Injury Induced by Oxidized Low Density Lipoprotein
양승택, Yang. Seung-Taek 한국생명과학회 생명과학회지 8 Pages
한국생명과학회 생명과학회지 2010, Vol.20 No.11 1595-1602 (8 pages)
LDH와 GSH 함량을 조사하였다. 본 실험 결과 allylmercaptan을 일정 농도 별로 endothelial cell에 첨가하여 배양했을 때 LDH의 방출과 GSH의 감소를 현저하게 억제하였다. Peroxide를 형광분석법으로 24 well plate에서 직접 측정한 결과 allylmercaptan이 폐동맥 내피세포 내에서 ox-LDL 유도 peroxide의 방출을 억제하였다. 그리고 allylmercaptan은 과산화수소의 소거능도 있었다. 본 실험결과 allylmercaptan은 ox-LDL 유도 폐동맥 내피세포를 보호할 수 있었으므로 allylmercaptan은 동맥경화의 예방에 유용할 것으로 생각된다. -
Tissue microarray를 이용한 사이모신 베타4(Thymosin β4)와 vascular endothelial cell growth factor (VEGF)의 정상 인간 조직 발현 양상 연구
옥미선, 차희재, Ock. Mee-Sun, Cha. Hee-Jae 한국생명과학회 생명과학회지 10 Pages
한국생명과학회 생명과학회지 2009, Vol.19 No.12 1777-1786 (10 pages)
사이모신 베타 4와 VEGF의 발현을 여러 인간 조직에서 tissue microarray를 사용하여 조사하였다. 사이모신 베타 4는 간, 이자, 침샘의 관상피, 심장에서 강한 발현을 보였으며 피부, 폐, 이자, 림프절, 갑상선, 요관, 폐와 부신의 혈관 내피세포 등에서 중간 수준의 발현 양상을 보였다. VEGF의 발현 양상은 대체적으로 사이모신 베타 4와 동일하였으며 이자, 요관, 유선, 간, 식도, 신장, 폐, 부신 등의 혈관 내피세포에서 강하게 발현되었다. 이러한 결과를 통해 사이모신 베타 4는 간, 이자, 침샘의 관상피, 심장에서 중요한 역할을... -
Effect of Overexpressed Ref-1 on AKT Phosphorylation for NO Production in Mouse Aortic Endothelial Cell Line
송주동, 이상권, 박영철, Song. Ju-Dong, Lee. Sang-Kwon, Park. Young-Chul 한국생명과학회 생명과학회지 6 Pages
한국생명과학회 생명과학회지 2008, Vol.18 No.12 1651-1656 (6 pages)
Redox factor-1 (Ref-1)은 산화적으로 손상된 DNA의 복구와 세포내 산화환원에 민감한 전사인자들의 활성화에 필수적인 역할을 수행한다. 본 연구에서는 마우스 유래 혈관내피세포주 (MAE)에서 nitric oxide (NO) 생성과정에 관여하는 AKT 활성화의 측면에서 adenoviral vector를 사용하여 과발현된 Ref-1의 역할을 살펴보았다. NO 측정을 위하여 fluorophore DAF-2를 사용하였다. 과발현된 Ref-1은 bradykinin으로 자극한 세포뿐만 아니라 자극되지 않은 세포의 NO 생성도 증가시켰다. 놀랍게도 이 과발현된 Ref-1은 AKT의 직접적인... -
Methanolic Extract Isolated from Root of Lycoris aurea Inhibits Cancer Cell Growth and Endothelial Cell Tube Formation In Vitro
Kang. Moo-Rim, Lee. Chang-Woo, Yun. Ji-Eun, Oh. Soo-Jin, Park. Song-Kyu, Lee. Ki-Ho, Kim. Hwan-Mook, Han. Sang-Bae, Kim. Hyoung-Chin, Kan 한국독성학회 Toxicological research 6 Pages
한국독성학회 Toxicological research 2012, Vol.28 No.1 33-38 (6 pages)
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Photodynamically induced endothelial cell injury and neutrophil-like HL-60 adhesion
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한국광과학회 Journal of photoscience: an international journal officail organ of the Korean Society of Photoscien 2002, Vol.9 No.2 518-520 (3 pages)
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Serum Vascular Endothelial Growth Factor-A (VEGF-A) as a Biomarker in Squamous Cell Carcinoma of Head and Neck Patients Undergoing Chemoradiotherapy
Srivastava. Vikas Kumar, Gara. Rishi Kumar, Rastogi. Namrata, Mishra. Durga Prasad, Ahmed. Mohd Kaleem, Gupta. Shalini, Goel. Madhu Ma 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 5 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2014, Vol.15 No.7 3261-3265 (5 pages)
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Serum Tumor Markers, Hypoxia-Inducible factor-1α HIF-1α and Vascular Endothelial Growth Factor, in Patients with Non-small Cell Lung Cancer Before and after Intervention
Liang. Jun, Qian. Ying, Xu. Dan, Yin. Qun, Pan. Hui-Juan 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 4 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2013, Vol.14 No.6 3851-3854 (4 pages)
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Norcantharidin Anti-Angiogenesis Activity Possibly through an Endothelial Cell Pathway in Human Colorectal Cancer
Yu. Tao, Hou. Fenggang, Liu. Manman, Zhou. Lihong, Li. Dan, Liu. Jianrong, Fan. Zhongze, Li. Qi 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 5 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2012, Vol.13 No.2 499-503 (5 pages)
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Prevalence and Clinical Significance of Mammalian Target of Rapamycin Phosphorylation (p-mTOR) and Vascular Endothelial Growth Factor (VEGF) in Clear Cell Carcinoma of the Ovary
Khemapech. Nipon, Pitchaiprasert. Sunaree, Triratanachat. Surang 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 6 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2012, Vol.13 No.12 6357-6362 (6 pages)
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Effect of Tea Polyphenols on the Adhesion of Highly Metastatic Human Lung Carcinoma Cell Lines to Endothelial Cells in Vitro
Zheng. Feng-Jin, Shi. Lin, Yang. Jun, Deng. Xiao-Hui, Wu. Yu-Quan, Yan. Xi-Qing, Huang. Ning 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 5 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2012, Vol.13 No.8 3751-3755 (5 pages)
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Computational Analysis on Calcium Dynamics of Vascular Endothelial Cell Modulated by Physiological Shear Stress
Kang. Hyun-Goo, Lee. Eun-Seok, Shim. Eun-Bo, Chnag. Keun-Shik 순환기의공학회 International Journal of Vascular Biomedical Engineering 9 Pages
순환기의공학회 International Journal of Vascular Biomedical Engineering 2005, Vol.3 No.2 1-9 (9 pages)
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Identification of p54nrb and the 14-3-3 Protein HS1 as TNF-α-Inducible Genes Related to Cell Cycle Control and Apoptosis in Human Arterial Endothelial Cells
Stier. Sebastian, Totzke. Gudrun, Grunewald. Elisabeth, Neuhaus. Thomas, Fronhoffs. Stefan, Schoneborn. Silke, Vetter. Hans, Ko. Yon 생화학분자생물학회 Journal of biochemistry and molecular biology 10 Pages
생화학분자생물학회 Journal of biochemistry and molecular biology 2005, Vol.38 No.4 447-456 (10 pages)
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Endothelial progenitor cell transplantation decreases lymphangiogenesis and adverse myocardial remodeling in a mouse model of acute myocardial infarction
Park. Jae-Hyeong, Yoon. Jung-Yeon, Ko. Seon-Mi, Jin. Seon-Ah, Kim. Jun-Hyung, Cho. Chung-Hyun, Kim. Jin-Man, Lee. Jae-Hwan, Choi. Si-Wan 생화학분자생물학회 Experimental & molecular medicine : EMM 7 Pages
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