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쑥갓의 꽃에서 분리한 sesquiterpene lactones의 항균활성
하태정, 한효심, 장기창, 장대식, 조동령, 양민석, 이경동, Ha. Tae-Jung, Han. Hyo-Shim, Jang. Ki-Chang, Jang. Dae-Sik, Cho. Dong-Young, Yang. Min-Suk, Lee. Kyung-Don 한국응용생명화학회 한국농화학회지 5 Pages
한국응용생명화학회 한국농화학회지 2003, Vol.46 No.3 235-239 (5 pages)
쑥갓(Chrysanthemum coronapium L.)의 꽃에서 분리한 13개의 sesequiterpene lactone들에 대한 생리활성 실험의 일환으로, 세균 8종과 곰팡이 5종을 이용하여 항미생물 활성을 검토하였다. 그 결과, 항세균 실험에서 Gram 양성균인 Bacillus subtilis, Bacillus cereus, Staphylococcus aureus 균들과 Gram 음성균인 Vibrio parahaemolyticus균이 쑥갓에서 분리된 13종의 화합물들에 대하여 광범위한 활성을 나타내었으며, 이들 중에 dihydrochrysanolide 유도체가 Staphylococcus aureus균에서 $3.1;{mu}g{cdot}disc^{-1}$이하의 강한... -
지칭개, 구절초 및 산국에서 분리한 Sesquiterpene lactones의 항균활성
장대식, 박기훈, 이종록, 하태정, 박윤배, 남상해, 양민석, Jang. Dae-Sik, Park. Ki-Hun, Lee. Jong-Rok, Ha. Tae-Joung, Park. Yun-Bae, Nam. Sang-Hae, Yang. Min-Suk 한국응용생명화학회 한국농화학회지 4 Pages
한국응용생명화학회 한국농화학회지 1999, Vol.42 No.2 176-179 (4 pages)
지칭개, 구절초 및 산국에서 분리한 9종류의 sesquiterpene lactones에 대한 생리활성 실험의 일환으로, 10종의 세균에 대한 항세균활성과 6종의 식물병원균에 대한 항진균활성을 조사하였다. 항세균 활성실험에서는 지칭개에서 분리한 hemistepsin A와 B 그리고 산국에서 분리한 tulipinolide가 시험균주 전반에 대하여 강한 활성을 보였으며, 항진균 활성실험에서는 hemistepsin B, angeloylcumambrin B, tigloylcumambrin B, 그리고 costunolide가 광범위한 활성을 보였다. 또한, 항세균 활성실험과 항진균 활성실험 모두 비교적... -
산국으로부터 분리한 Sesquiterpene Lactones의 흰쥐 복수암에 대한 효과
남상해, 최상도, 최진상, 장대식, 최상욱, 양민석 한국식품영양과학회 한국식품영양과학회지 4 Pages
한국식품영양과학회 한국식품영양과학회지 1997, Vol.26 No.1 144-147 (4 pages)
산국의 꽃으로부터 2종의 sesquiterpene lactones을 분리정제하였으며, 각각 Compound I 과 II로 명명하였으며, 이 두 물질을 Sarcoma180에 감염된 ICR mouse에 대하여 항암효과실험을 수행한 결과 Compound I과 II의 투여농도가 10mg/kg일 때 수명 연장효과가 각 각 143%, 134%로 나타났다. 또한 Compound I 과 II 를 1mg/kg 씩을 섞어서 투여하였을 때에 158%의 수명 연장효과가 나타났다 -
Isolation of Magnolialide and Artesin from Cichorium intybus: Revised Structures of Sesquiterpene Lactones
Park. Hee-Juhn, Kwon. Sang-Hyuk, Yoo. Ki-Oug, Jung. Won-Tae, Lee. Kyung-Tae, Kim. Joo-Il, Han. Yong-Nam 한국생약학회 Natural product sciences 5 Pages
한국생약학회 Natural product sciences 2000, Vol.6 No.2 86-90 (5 pages)
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A Highly Diastereoselective Cyclocarbonylation of Allene-Aldehyde Mediated by Mo(CO)6: Synthesis of Bicyclic Lactones
Ko. Kyoung-Jun, Kim. Sang-Hoon, Kim. Yu-Rim, Min. Dong-Won, Yu. Chan-Mo 대한화학회 Bulletin of the Korean Chemical Society 2 Pages
대한화학회 Bulletin of the Korean Chemical Society 2007, Vol.28 No.11 1921-1922 (2 pages)
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Cephalosporolides H and I, Two Novel Lactones from a Marine-Derived Fungus, Penicillium sp.
Yao. Yanhua, Zheng. Yinan, Sattler. Isabel, Lin. Wenhan, Li. Xiang 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 4 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2007, Vol.30 No.7 812-815 (4 pages)
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Cytotoxic Germacranolide Sesquiterpene Lactones from Carpesium triste var. manshuricum
Kim. Mi-Ran, Hwang. Bang-Yeon, Jeong. Eun-Sook, Yoo. Hwan-Soo, Chung. Youn-Bok, Hong. Jin-Tae, Moon. Dong-Cheul 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 5 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2007, Vol.30 No.5 556-560 (5 pages)
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Cytotoxic and ACAT-inhibitory Sesquiterpene Lactones from the Root of Ixeris dentata forma albiflora
Ahn. Eun-Mi, Bang. Myun-Ho, Song. Myoung-Chong, Park. Mi-Hyun, Kim. Hwa-Young, Kwon. Byoung-Mog, Baek. Nam-In 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 5 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2006, Vol.29 No.11 937-941 (5 pages)
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Cytotoxic Sesquiterpene Lactones from Saussurea calcicola
Choi. Sang-Zin, Choi. Sang-Un, Lee. Kang-Ro 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 5 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2005, Vol.28 No.10 1142-1146 (5 pages)
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Cytotoxic Effects of Sesquiterpene Lactones from the Flowers of Hemisteptia Iyrata B.
Ha. Tae-Joung, Jang. Dae-Sik, Lee. Jong-Rok, Lee. Kyung-Dong, Lee. Jun, Hwang. Seon-Woo, Jung. Hwa-Jin, Nam. Sang-Hae, Park. Ki-Hun, Yang 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 4 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2003, Vol.26 No.11 925-928 (4 pages)
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Novel insertion mutation of ABCB1 gene in an ivermectin-sensitive Border Collie
Jae-Ik Han, Hyoung-Won Son, Seung-Cheol Park, Ki-Jeong Na* 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2010, 제 11권 제 4호 10 341-344 (4 pages)
P-glycoprotein (P-gp) is encoded by the ABCB1 gene and acts as an efflux pump for xenobiotics. In the Border Collie, a nonsense mutation caused by a 4-base pair deletion in the ABCB1 gene is associated with a premature stop to P-gp synthesis. In this study, we examined the full- length coding sequence of the ABCB1 gene in an ivermectin- sensitive Border Collie that lacked the aforementioned deletion mutation. The sequence was compared to the corresponding sequences of a wild-type Beagle and... -
Effects of C18 Fatty Acids on Intracellular Ca2+ Mobilization and Histamine Release in RBL-2H3 Cells
MyungChulKim, MinGyuKim, YoungSooJo, HoSunSong, TaeInEom, SangSooSim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.3 7 241-247 (7 pages)
To investigate the underlying mechanisms of C18 fatty acids (stearic acid, oleic acid, linoleic acid and α-linolenic acid) on mast cells, we measured the effect of C18 fatty acids on intracellular Ca2+ mobilization and histamine release in RBL-2H3 mast cells. Stearic acid rapidly increased initial peak of intracellular Ca2+ mobilization, whereas linoleic acid and α-linolenic acid gradually increased this mobilization. In the absence of extracellular Ca2+, stearic acid (100 μM) did not cause... -
Intracellular Ca2＋ Mobilization and Beta-hexosaminidase Release Are Not Influenced by 60 Hz-electromagnetic Fields (EMF) in RBL 2H3 Cells
YeonHeeHwang, HoSunSong, HeeRaeKim, MyoungSooKo, JaeMinJeong, YongHoKim, JeongSooRyu, UyDongSohn, Yoon-MyoungGimm, SungHoMyung, SangSooSim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.5 10 313-317 (5 pages)
The effects of extremely low frequency electromagnetic fields (EMF) on intracellular Ca2＋ mobilization and cellular function in RBL 2H3 cells were investigated. Exposure to EMF (60 Hz, 0.1 or 1 mT) for 4 or 16 h did not produce any cytotoxic effects in RBL 2H3 cells. Melittin, ionomycin and thapsigargin each dose-dependently increased the intracellular Ca2＋ concentration. The increase of intracellular Ca2＋ induced by these three agents was not affected by exposure to EMF (60 Hz, 1 mT) for 4... -
Diphenylhydantoin 및 Ouabain 이 흰쥐 적혈구세포막 ATPase에 미치는 영향
박찬웅(Park, Chan-Woong), 대한약리학회 대한약리학잡지 8 Pages
대한약리학회 대한약리학잡지 1970, 제 6권 제 1호 1 1-8 (8 pages)
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Phytoplasma Infection could Affect Chemical Composition of Artemisia sieberi
Chamran Hemmati, Mehrnoosh Nikooei 한국식물병리학회 The Plant Pathology Journal 6 Pages
한국식물병리학회 The Plant Pathology Journal 2019, 35권 3호 8 274-279 (6 pages)
Artemisia sieberi showing symptoms resembling those caused by phytoplasma were observed in Geno Mountain, Hormozgan Province, Iran, and were examined for phytoplasma presence by PCR assays. In addition, the essential oils hydrodistilled from the aerial parts of phytoplasma-infected and healthy plants have been analyzed and compared by GC and GC/MS. Phylogenetic and virtual RFLP analysis of the 16S rRNA gene sequences revealed that the phytoplasma associated with A. sieberi witches’ broom (AsWB)...
