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본문검색 결과만 보기
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The role of pH in magnesium homeostasis of heart
Shang Jin Kim 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 85 230-230 (1 pages)
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Tissue distribution of marbofloxacin in pigs after a single intramuscular injection
Fan Yang, Yiming Liu, Zhili Li, Yuqin Wang, Baobao Liu, Zhensheng Zhao, Bianhua Zhou, Guoyong Wang 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 2호 6 169-173 (5 pages)
Tissue distribution of marbofloxacin was studied in pigs after a single intramuscular injection at 2.5 mg/kg body weight. Samples of plasma, muscle, liver, kidney, heart, lung, and muscle at the injection site were randomly collected from five pigs at 2, 6, 10, 24, 48, 72, and 96 h after administration. Marbofloxacin concentrations were determined by using high-performance liquid chromatography with ultraviolet detection and were subjected to non-compartmental analysis to obtain kinetic... -
Claudin-1, -2, -4, and -5: comparison of expression levels and distribution in equine tissues
Bonn Lee, Hee Young Kang, Dong Oh Lee, Changhwan Ahn, Eui-Bae Jeung 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 4호 2 445-451 (7 pages)
In this study, the expression level and distribution of claudin-1, -2, -4, and -5 in eight tissues were assessed by Western blotting and immunohistochemistry methods. Claudin-1 was primarily identified in the lung, duodenum, and uterus, claudin-2 was evenly observed in equine tissues, claudin-4 was abundantly detected in the liver, kidney and uterus, and claudin-5 was strongly expressed in the lung, duodenum, ovary, and uterus, as determined by Western blotting method. The localization of equine... -
Preparation and evaluation of enrofloxacin microspheres and tissue distribution in rats
Fan Yang, Jijun Kang, Fang Yang, Zhensheng Zhao, Tao Kong, Zhenling Zeng 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 2호 4 157-164 (8 pages)
New enrofloxacin microspheres were formulated, and their physical properties, lung-targeting ability, and tissue distribution in rats were examined. The microspheres had a regular and round shape. The mean diameter was 10.06 μm, and the diameter of 89.93% of all microspheres ranged from 7.0 μm to 30.0 μm. Tissue distribution of the microspheres was evaluated along with a conventional enrofloxacin preparation after a single intravenous injection (7.5 mg of enrofloxacin/kg bw). The results... -
The production and distribution of IL-6 and TNF-α in subcutaneous adipose tissue and their correlation with serum concentrations in Welsh ponies with equine metabolic syndrome
Katarzyna Basinska, Krzysztof Marycz, Agnieszka ?mieszek, Jakub Nicpo? 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 1호 15 113-120 (8 pages)
A main symptom of equine metabolic syndrome (EMS) in ponies is pathological obesity characterized by abnormal accumulation of fat deposits and inflammation. In this study, we analyzed the expression of two pro-inflammatory cytokines, interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α), in subcutaneous adipose tissue and the correlation with serum concentrations in peripheral blood of Welsh ponies. Based on clinical examination findings, the animals were... -
Effect of chronic lead intoxication on the distribution and elimination of amoxicillin in goats
Ahmed M. Soliman, Ehab A. Abu-Basha, Salah A. H. Youssef, Aziza M. Amer, Patricia A. Murphy, Catherine C. Hauck, Ronette Gehring 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2013, 제 14권 제 4호 4 395-403 (9 pages)
half-lives were 4.14 and 1.26 h, respectively. The volumes of distribution based on the terminal phase were 1.19 and 0.38 L/kg, respectively, and those at steady-state were 0.54 and 0.18 L/kg, respectively. After intramuscular (IM) amoxicillin (10 mg/kg bw) in lead-intoxicated goats and control animals, the absorption, distribution, and elimination of the drug were more rapid in lead-intoxicated goats than the controls. Peak serum concentrations of 21.89 and 12.19 μg/mL were achieved at 1 h and... -
Distribution and characterization of IL-10-secreting cells in lymphoid tissues of PCV2-infected pigs
Alan R. Doster, Sakthivel Subramaniam, Ji-Young Yhee, Byung-Joon Kwon, Chi-Ho Yu, So-Young Kwon, Fernando A. Osorio, Jung-Hyang 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2010, 제 11권 제 3호 1 177-183 (7 pages)
Distribution and characterization of interlukin-10 (IL-10)- secreting cells in lymphoid tissues of pigs naturally infected with porcine circovirus type 2 (PCV2) were evaluated in accordance with PCV2 antigen detection. After screening a total of 56 pigs showing the symptoms of postweaning multisystemic wasting syndrome (PMWS), 15 pigs were PCV2 positive and 5 pigs, which showed stronger positive signals over multiples tissues were further investigated. This study showed that in PCV2-infected... -
Distribution of the putative virulence factor encoding gene sheta in Staphylococcus hyicus strains of various origins
Talah Kanbar, Andrey V. Voytenko, Jörg Alber, Christoph Lämmler, Reinhard Weiss, Vladimir N. Skvortzov 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 3호 14 327-330 (4 pages)
In the present study, Staphylococcus (S.) hyicus strains isolated in Russia (n = 23) and Germany (n = 17) were investigated for the prevalence of the previously described genes sheta and shetb. Sheta was detected in 16 S. hyicus strains. Sheta-positive strains were mainly found among strains isolated from exudative epidermitis, and frequently together with the exfoliative toxin-encoding genes exhD and exhC. Partial sequencing of sheta in a single S. hyicus strain revealed an almost complete... -
Distribution of trkA in cerebral cortex and diencephalon of the mongolian gerbil after birth
Il-Kwon Park, Xilin Hou, Kyung-Youl Lee, O-Sung Park, Kang-Yi Lee, Min-Young Kim, Tae-Sun Min, Geun-Jwa Lee, Won-Sik Kim, Moo-Kan 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2004, 제 5권 제 4호 4 303-307 (5 pages)
TrkA is essential components of the high-affinity NGF receptor necessary to mediate biological effects of the neurotrophins NGF. Here we report on the expression of trkA in the cerebral cortex and diencephalon of mongolian gerbils during postnatal development. The expression of trkA was identified by immunohistochemical method. In parietal cortex and piriform cortex, higher levels of trkA-IR (immunoreactivity) were detected at 3 days postnatal (P3) and at P9. Although trkA was not expressed till... -
Regional Distribution and Relative Frequency of Gastrointestinal Endocrine Cells in Large Intestines of C57BL/6 Mice
Tae-Su Ham 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 3호 13 233-238 (6 pages)
The regional distributions and relative frequencies of some gastrointestinal endocrine cells in the three portions (cecum, colon and rectum) of the large intestinal tract of C57BL/6 mice were examined with immunohistochemical method using 7 types of specific antisera against chromogranin A (CGA), serotonin, somatostatin, human pancreatic polypeptide (HPP), glucagon, gastrin and cholecyctokinin (CCK)-8. In this study, all 3 types of immunoreactive (IR) cells were identified. Most of these IR... -
Effects of acidic pH on voltage-gated ion channels in rat trigeminal mesencephalic nucleus neurons
Jin-EonHan, Jin-HwaCho, In-SunChoi, Do-YeonKim, Il-SungJang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.2 9 215-223 (9 pages)
voltage-dependent Ca2+ channels were significantly inhibited by an acidic pH. The application of an acidic pH solution significantly shifted the current-voltage and conductance-voltage relationships to the depolarization range. The modulation of several voltage-dependent ion channels by an acidic pH might affect the excitability of mesencephalic trigeminal nucleus neurons, and thus physiological functions mediated by the mesencephalic trigeminal nucleus could be affected in acidic pH conditions. -
Regional Distribution of Interstitial Cells of Cajal (ICC) in Human Stomach
Hyo-YungYun, RohyunSung, YoungChulKim, WoongChoi, HunSikKim, HeonKim, GwangJuLee, RaYoungYou, Seon-MeePark, SeiJinYun, Mi-JungKim, WonSeopK 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.5 11 317-324 (8 pages)
which had morphology very similar to ICC were found in gastric mucosa. We could not find any significant difference in the distribution of ICC between fundus and corpus, except for submucosa where the density of ICC was much higher in gastric fundus than corpus. Furthermore, there was no significant difference in the density of ICC between each area of fundus and corpus, except for muscularis mucosa. Finally, we also found similar distribution of ICC in normal and cancerous tissue obtained from... -
Asymmetrical Distribution of P2Y Nucleotide Receptors in Rabbit Inner Medullary Collecting Duct Cells
JaeSukWoo, JinSupJung, YongKeunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.4 6 311-318 (8 pages)
We cultured the rabbit inner medullary collecting duct (IMCD) cells as monolayers on collagen-coated membrane filters, and investigated distribution of the P2Y receptors by analyzing nucleotide-induced short circuit current (Isc) responses. Exposure to different nucleotides of either the apical or basolateral surface of cell monolayers stimulated Isc. Dose-response relationship and cross-desensitization studies suggested that at least 3 distinct P2Y receptors are expressed asymmetrically on the... -
Distribution, Content and Molecular Heterogeneity of Gastrin- Releasing Peptide in Rat Pancreas
HyungSeoParkHyoungJinPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.4 7 427-432 (6 pages)
Although importance of intrapancreatic neurons containing gastrin-releasing peptide (GRP) in control of exocrine secretion has been raised, the nature of GRP in the pancreas is unclear. Thus, the present study was undertaken to see distribution, content and molecular heterogeneity of immunoreactive GRP in the rat pancreas. Content of immunoreactive GRP in the rat pancreas was 2.99 ⁑ 0.66 ng/g wet tissues determined by radioimmunoassay. Immunoreactive GRP was most abundantly expressed in... -
External pH Effects on Delayed Rectifier K+ Currents of Small Dorsal Root Ganglion Neuron of Rat
YoungHoKim, JungHyunHahn, InJaLim, SungkwonChung, HyoWeonBang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.2 4 165-172 (8 pages)
pH. In this study, the whole cell configuration of the patch clamp technique has been applied to the recording of the responses of change of external pH on the delayed rectifier K+ current of cultured DRG neurons of rat. Outward K+ currents were examined in DRG cells, and the Charybdotoxin and Mn2+ could eliminate Ca2+-dependent K+ currents from outward K+ currents. This outward K+ current was activated around 60 mV by step depolarizing pulses from holding potential 70 mV. Outward... -
Effect of pH on Calcium-Activated Potassium Channels in Pulmonary Arterial Smooth Muscle Cells of the Rabbit
Lee, Suk-Ho, Ho, Won-Kyung, Earm, Yung-E 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1991, 제 25권 제 1호 2 17-26 (10 pages)
by increasing [Ca2+]i, was an unexpected result and one additional closed state which might be arisen from a block of the open channel by Ca binding was suggested. The P0-membrane potential relationship was modulated by internal pH. Decreasing pH reduced P0. Increasing pH not only increased P0 but also weakened the voltage dependency of the channel opening. The modulation of Ca-activated K channel by pH was thought to be related to the mechanism of regulation of vascular tone by the pH change. -
아로마용액과 0.9% N/S 구강함수가 간호대학생의 구강건조, 구취 및 타액 pH에 미치는 효과 비교
조미경, 조윤희 한국기초간호학회 Journal of Korean Biological Nursing Science 9 Pages
한국기초간호학회 Journal of Korean Biological Nursing Science 2014, Volume 16, No 2 9 141-149 (9 pages)
구강건조 및 구취 등은 개인에게 불편감을 줄 뿐만 아니라 상대방에게 불쾌감을 유발하는 등 대인관계에도 영향을 미치는 요소 중 하나이며(Krespi, Shrime, & Kacker, 2006), 전신건강상태 및 건강관련 삶의 질과도 연관이 있다(Kim, Kang, & Jeong, 2010). 따라서 구강간호는 간호대상자의 안위를 살피는 간호사에게 있어서 기본적 간호중재 중 하나이다. -
도림천 상류의 pH, NO3 -, PO4 3-와 식물성 플랑크톤 분포와의 관계
김재근, 김태현, 유지민, 이주연 한국습지학회 한국습지학회지 9 Pages
한국습지학회 한국습지학회지 2012, Vol.14 No.2 10 255-263 (9 pages)
농도 그리고 식물성 플랑크톤을 조사하였다. pH는 5.05 ~ 7.56의 범위에 있었으며, NO3 -와 PO4 3-의 농도는 0.4 ~ 4.9ppm와 0.02 ~ 0.99ppm의 범위에 있었다. 서울대학 교로부터 PO4 3-이 유입되는 것으로 확인되었지만 그 농도는 그리 높지 않았으며, 400m 정도 지나면 거의 모두 정화되었다. NO3 -/PO4 3- 비율은 유입되는 PO4 3-의 영향을 받는 곳을 제외하면 28 ~ 152의 범위로 나타났다. pH, NO3 -, PO4 3-의 농도는 하류로 갈수록 증가하였으며, 이는 한강 본류에서 끌어온 물의 유입뿐만 아니라 비점 오염원으로부터의 유입과... -
생리식염수를 이용한 구강함수가 요양시설노인의 구강건강상태, 구강건조, 구취, 타액 pH 변화에 미치는 효과
정선아, 조은아 한국노인간호학회 노인간호학회지 11 Pages
한국노인간호학회 노인간호학회지 2017, 제 19권 제 3호 2 173-183 (11 pages)
우리나라 노인의 경우 80%가 만성퇴행성 질환으로 신체적 문제를 겪고 있고 신체기능 저하로 인한 기능장애 및 병리적 변화 등으로 다양한 건강 관련 문제가 발생할 수 있으므로 노 인들의 행복한 삶을 유지하기 위해서는 건강과 관련된 문제를 주의깊게 관리할 필요가 있다[1-3]. -
동관에서 pH, 알칼리도, 염소이온이 부식에 미치는 영향
조관형, 김선일, 우달식, Jo. Kwan-Hyung, Kim. Sun-Il, Woo. Dal-Sik 한국환경보건학회 韓國環境保健學會誌 6 Pages
한국환경보건학회 韓國環境保健學會誌 2007, Vol.33 No.1 43-48 (6 pages)
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Variations of Disinfection By-products in a Chlorinated Drinking Water Distribution System
Lee. Soo-Hyung, Park. Jeong-Kun, Lee. Hyung-Jun, Kim. He-Kap 한국환경과학회 Environmental sciences : bulletin of The Korean Environmental Sciences Society 8 Pages
한국환경과학회 Environmental sciences : bulletin of The Korean Environmental Sciences Society 2000, Vol.4 No.2 71-78 (8 pages)
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역류분배를 이용한 모델단백질의 분리정제시 pH의 영향에 관한 연구
이부용, 이창호, 이철호, Lee. Boo-Yong, Lee. Chang-Ho, Lee. Cherl-Ho 한국식품과학회 한국식품과학회지 5 Pages
한국식품과학회 한국식품과학회지 1990, Vol.22 No.1 56-60 (5 pages)
역류분배 방법을 이용한 단백질의 분리정제 가능성을 높이기 위하여 4가지 모델단백질에 대하여 수용성 액체 2상계에서의 분획계수를 pH 변화에 따라 조사하였다. 또한 역류분배를 이용한 다중분배추출방식으로 모델 단백질의 혼합물을 수준의 pH(4.5-12.0)에서 분획하였다. 그 결과 pH에 따라 단백질들의 등전점 차이로 인한 분획계수(K)값이 다르게 나타서, 다중분배를 행할 때 각 단백질 분획들이 위치하는 튜브번호가 다르게 되므로 역류분배 방법을 통한 단백질의 분리 가능성을 보여주었다.
