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Pineal Photoreceptor and Ganglion Cells in River Lamprey, Lampetra japonica -Two Types of Pineal Ganglion Cell-
Tamotsu. Satoshi, Kinugawa. Yoshimi, Kawano. Emi, Watanabe. Mai, Samejima. Michikazu, Oishi. Tadashi 한국광과학회 Journal of photoscience: an international journal officail organ of the Korean Society of Photoscien 4 Pages
한국광과학회 Journal of photoscience: an international journal officail organ of the Korean Society of Photoscien 2002, Vol.9 No.2 21-24 (4 pages)
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Direct conversion of human AESCs and UCB-MSCs into cone and rod photoreceptor-like cells by inhibition of microRNA-203
Soon Won Choi, Ji Hee Shin, Jae Jun Kim, Tae Hoon Shin, Myung Geun Kook, Yoojin Seo, Hyung Sik Kim, Kyung Sun Kang 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 272 341-341 (1 pages)
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Overexpression of Ref-1 Inhibits Lead-induced Endothelial Cell Death via the Upregulation of Catalase
KwonHoLee, SangKiLee, HyoShinKim, EunJungCho, HeeKyoungJoo, EunJiLee, JiYoungLee, MyoungSooPark, SeokJongChang, Chung-HyunCho, JinBongPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.6 4 431-436 (6 pages)
in a concentration- and time-dependent manner. However, Ref-1 overexpression with AdRef-1 significantly inhibited Pb-induced cell death in the endothelial cells. Also the overexpression of Ref-1 significantly suppressed Pb-induced superoxide and hydrogen peroxide elevation in the endothelial cells. Pb exposure induced the downregulation of catalase, it was inhibited by the Ref-1 overexpression in the endothelial cells. Taken together, our data suggests that the overexpression of Ref-1 inhibited... -
Stem Cell Based Strategies for the Treatment of Degenerative Retinal Diseases
박정현, 구승엽, 조명수, 이학섭, 최영민, 문신용, 유형곤, Park. Jung-Hyun, Ku. Seung-Yup, Cho. Myung-Soo, Lee. Hak-Sup, Choi. Young-Min, Moon. Shin-Yong, Yu. Hyeong 대한생식의학회 대한생식의학회지= The Korean journal of reproductive medicine 8 Pages
대한생식의학회 대한생식의학회지= The Korean journal of reproductive medicine 2010, Vol.37 No.3 199-206 (8 pages)
망막 질환에서의 줄기세포 치료는 이전까지 치료가 불가능하다고 여겨졌던 환자들에서 시력을 향상시킬 수 있는 가능성 때문에 주목 받고 있다. 본문에서는 망막 전구세포의 분화를 위해 사용되는 태아 줄기세포, 배아줄기세포 및 성체줄기세포 등 다양한 세포 종류와, 내인적, 외인적 인자 및 이식 방법에 대해 논의하였다. 망막색소상피세포뿐만 아니라 시각세포 전구체로 성공적으로 분화시킨 실험적 연구가 보고되고 있다. 줄기세포기반치료는 아직 한계가 있지만 망막 질환 환자에서 시력을 회복하기 위한 보다 근본적인 치료... -
A serine/threonine phosphatase 1 of Streptococcus suis type 2 is an important virulence factor
Lihua Fang, Jingjing Zhou, Pengcheng Fan, Yunkai Yang, Hongxia Shen, Weihuan Fang 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 4호 3 439-447 (9 pages)
Streptococcus suis is regarded as one of the major pathogens of pigs, and Streptococcus suis type 2 (SS2) is considered a zoonotic bacterium based on its ability to cause meningitis and streptococcal toxic shock-like syndrome in humans. Many bacterial species contain genes encoding serine/threonine protein phosphatases (STPs) responsible for dephosphorylation of their substrates in a single reaction step. This study investigated the role of stp1 in the pathogenesis of SS2. An isogenic stp1... -
Inhibition by miR-410 facilitates direct retinal pigment epithelium differentiation of umbilical cord blood-derived mesenchymal stem cells
Soon Won Choi, Jae-Jun Kim, Min-Soo Seo, Sang-Bum Park, Tae-Hoon Shin, Ji-Hee Shin, Yoojin Seo, Hyung-Sik Kim, Kyung-Sun Kang 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 1호 8 59-65 (7 pages)
is a major component of the eye. This highly specialized cell type facilitates maintenance of the visual system. Because RPE loss induces an irreversible visual impairment, RPE generation techniques have recently been investigated as a potential therapeutic approach to RPE degeneration. A microRNA-based technique is a new strategy for producing RPE cells from adult stem cell sources. Previously, we identified that antisense microRNA-410 (anti-miR-410) induces RPE differentiation from amniotic... -
Normal clinical electroretinography parameters for poodle, Labrador retriever, Thai ridgeback, and Thai Bangkaew
Metita Sussadee, Janjira Phavaphutanon, Kornchai Kornkaewrat, Aree Thayananuphat 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 1호 9 67-74 (8 pages)
The purpose of the present study was to establish normal electroretinogram (ERG) parameters using 56 normal eyes of four dog breeds common in Thailand: poodle, Labrador retriever, Thai ridgeback, and Thai Bangkaew. Standard ERG findings were bilaterally recorded using a handheld multi-species ERG unit with an ERG-jet lens electrode for 28 dogs under preanesthesia with diazepam, anesthesia with propofol, and anesthesia maintenance with isoflurane. There were significant... -
Black rice anthocyanidins prevent retinal photochemical damage via involvement of the AP-1/NF-κB/Caspase-1 pathway in Sprague-Dawley Rats
Hao Jia, Wei Chen, Xiaoping Yu, Xiuhua Wu, Shuai Li, Hong Liu, Jiru Liao, Weihua Liu, Mantian Mi, Longjian Liu, Daomei Cheng 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2013, 제 14권 제 3호 15 345-353 (9 pages)
The effects of black rice anthocyanidins (BRACs) on retinal damage induced by photochemical stress are not well known. In the present study, Sprague-Dawley rats were fed AIN-93M for 1 week, after which 80 rats were randomly divided into two groups and treated with (n = 40) or without BRACs (n = 40) for 15 days, respectively. After treatment, both groups were exposed to fluorescent light (3,000 ± 200 lux; 25°C), and the protective effect of dietary BRACs were evaluated afterwards. Our results... -
Electroretinography recordings using a light emitting diode active corneal electrode in healthy beagle dogs
Yoshiki Itoh, Seiya Maehara, Norihiko Itoh*, Kazuto Yamashita, Yasuharu Izumisawa 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2013, 제 14권 제 1호 11 77-84 (8 pages)
Electroretinography (ERG) is a well-established diagnostic procedure for objectively evaluating retinal function. In this study, ERG in beagle dogs, which are a popular experimental animal, was performed to determine the normal range of ERG variables and assess differences between the left and right eyes. ERG findings including rod, combined rod-cone, single-flash cone, and 30-Hz flicker responses were recorded with an LED-electrode in 43 sedated beagle dogs. The subjects were divided into young... -
Distribution of caveolin isoforms in the lemur retina
Ágnes I Berta, Anna L Kiss, Ákos Lukáts, Arnold Szabó, Ágoston Szél 대한수의학회 Journal of Veterinary Science 3 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 3호 15 295-297 (3 pages)
The distribution of caveolin isoforms was previously evaluated in the retinas of different species, but has not yet been described in the primate retina. In this study, the distribution of caveolins was assessed via immunochemistry using isoform-specific antibodies in the retina of the blackand- white ruffed lemur. Here, we report the presence of a variety of caveolin isoforms in many layers of the lemur retina. As normal human retinas were not available for research and the retinas of primates... -
Immunohistochemical study of caveolin-1 and -2 in the rat retina
Heechul Kim, Taeki Lee, Jeeyoung Lee, Meejung Ahn, Changjong Moon, Myung Bok Wie, Taekyun Shin 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 2호 1 101-104 (4 pages)
indicated that caveolin-1 was expressed in the majority of retinal layers, including the ganglion cell layer, inner plexiform layer, outer plexiform layer, and in the vascular endothelial cells of the retina. Caveolin-2 was primarily immunostained in the vessels, but in a few other elements as well. This is the first demonstration of caveolin differential expression in the retina of rats, and suggests that caveolin plays an important role in signal transduction in glial cells and neuronal cells. -
Original Article : Expression analysis of ciliary rootlet coiled coil protein mRNA during Xenopus development
Md. Mahfujur Rahman , In Shik Kim , Dong Choon Ahn , Ho Seong Cho , Won Il Kim , Bumseok Kim , Gee Wook Shin , Jungkee K 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 4 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2015, 제 55권 제 3호 5 181-184 (4 pages)
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당귀수산, 생강, 커큐민의 대사성 질환과 관련된 일과성 수용체 전압 이온통로조절에 관한 연구
김병주(Byung Joo Kim) 한방비만학회 대한한방비만학회지 9 Pages
한방비만학회 대한한방비만학회지 2018, 제 18권 제 1호 2 10-18 (9 pages)
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The advantage of topographic prominence-adopted filter for the detection of short-latency spikes of retinal ganglion cells
JungryulAhn, Myoung-HwanChoi, KwangsooKim, SolomonS.Senok, Dong-ilDanCho, Kyo-inKoo, YongsookGoo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.5 10 555-563 (9 pages)
Electrical stimulation through retinal prosthesis elicits both short and long-latency retinal ganglion cell (RGC) spikes. Because the short-latency RGC spike is usually obscured by electrical stimulus artifact, it is very important to isolate spike from stimulus artifact. Previously, we showed that topographic prominence (TP) discriminator based algorithm is valid and useful for artifact subtraction. In this study, we compared the performance of forward backward (FB) filter only vs. TP-adopted... -
Electrophysiological and Histologic Evaluation of the Time Course of Retinal Degeneration in the rd10 Mouse Model of Retinitis Pigmentosa
SeolAJae, KunNoAhn, JiYoungKim, JeHoonSeo, HyongKyuKim, YongSookGoo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.3 8 229-235 (7 pages)
but the frequency of power spectral peak of local field potential at PW3 and PW3.5 is significantly different among other age groups (p<0.05). Histologic examination of rd10 retinae showed significant decrease in thickness of the outer nuclear layer at PW3. TUNEL positive cells were most frequently observed at PW3. From these data, we confirm that in the rd10 mouse, the most precipitous retinal degeneration occurs between PW3∼PW4 and that photoreceptor degeneration is complete by PW5. -
Gap Junction Contributions to the Goldfish Electroretinogram at the Photopic Illumination Level
Doh-YeonKim, Chang-SubJung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.3 11 219-224 (6 pages)
Understanding how the b-wave of the electroretinogram (ERG) is generated by full-field light stimulation is still a challenge in visual neuroscience. To understand more about the origin of the b-wave, we studied the contributions of gap junctions to the ERG b-wave. Many types of retinal neurons are connected to similar and different neighboring neurons through gap junctions. The photopic (cone-dominated) ERG, stimulated by a small light beam, was recorded from goldfish (Carassius auratus) using... -
Spontaneous Oscillatory Rhythm in Retinal Activities of Two Retinal Degeneration (rd1 and rd10) Mice
YongSookGoo, KunNoAhn, YeongJunSong, SuHeokAhn, SeungKeeHan, SangBaekRyu, KyungHwanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.6 13 415-422 (8 pages)
Previously, we reported that besides retinal ganglion cell (RGC) spike, there is ∼10 Hz oscillatory rhythmic activity in local field potential (LFP) in retinal degeneration model, rd1 mice. The more recently identified rd10 mice have a later onset and slower rate of photoreceptor degeneration than the rd1 mice, providing more therapeutic potential. In this study, before adapting rd10 mice as a new animal model for our electrical stimulation study, we investigated electrical characteristics of... -
Electrically-evoked Neural Activities of rd1 Mice Retinal Ganglion Cells by Repetitive Pulse Stimulation
SangBaekRyu, JangHeeYe, JongSeungLee, YongSookGoo, ChiHyunKim, KyungHwanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.6 6 443-448 (6 pages)
For successful visual perception by visual prosthesis using electrical stimulation, it is essential to develop an effective stimulation strategy based on understanding of retinal ganglion cell (RGC) responses to electrical stimulation. We studied RGC responses to repetitive electrical stimulation pulses to develop a stimulation strategy using stimulation pulse frequency modulation. Retinal patches of photoreceptor-degenerated retinas from rd1 mice were attached to a planar multi-electrode array... -
Microarray Analysis of Differentially Expressed Genes in the Brains of Tubby Mice
JeongHoLee, ChulHoonKim, DongGooKim, YoungSooAhn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.2 4 91-98 (8 pages)
The tubby mouse is characterized by progressive retinal and cochlear degeneration and late-onset obesity. These phenotypes are caused by a loss-of-function mutation in the tub gene and are shared with several human syndromes, suggesting the importance of tubby protein in central nervous system (CNS) functioning. Although evidence suggests that tubby may act as a transcription factor mediating G-protein coupled receptor (GPCR) signaling, any downstream gene regulated by tubby has yet to be... -
Modulation of Ca2+-Activated Potassium Channels by cGMP- Dependent Signal Transduction Mechanism in Cerebral Arterial Smooth Muscle Cells of the Rabbit
JinHan, NariKim, KwangbokLee, EuiyongKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.6 2 439-444 (6 pages)
cell-attached and inside-out patch configurations of patch-clamp techniques. Both molsidomine derivative 3-morpholinosydnonimine-N-ethylcarbamide (SIN-1, 50μM) and 8-(4-Chlorophenylthio)-guanosine-3',5'-cyclic monophosphate (8-pCPT-cGMP, 100μM), a membrane-permeable analogue of cGMP, increased the KCa channel activity in the cell-attached patch configuration, and the effect was removed upon washout of the drugs. In inside-out patches, single-channel current amplitude was not changed by SIN-1... -
Electrophysiological Analysis of GABA and Glycine Action on Neurons of the Catfish Retina
Bai, Sun-Ho, Jung, Chang-Sub, Lee, Sung-Jong 대한생리학회 대한생리학회지 12 Pages
대한생리학회 대한생리학회지 1993, 제 27권 제 2호 5 163-174 (12 pages)
Vertebrate retinal neurons, like brain tracts farm complex synaptic relations in the enter and inner plexiform layers which ape equivalent to the central nervous system nuclei. The effects of γ-aminobutyric acid(GABA) and glycine on retinal neurons were explored to discern the mechanisms of action of neurotransmitters. Experiments were performed in the superfused retina-eyecup preparation of the channel catfish, Ictalurus punctatus, using intracellular electrophysiological techniques. The roles... -
Induction of Drought Stress Resistance by Multi-Functional PGPR Bacillus Licheniformis K11 in Pepper
한국식물병리학회 The Plant Pathology Journal 8 Pages
한국식물병리학회 The Plant Pathology Journal 2013, 29권 2호 10 201-208 (8 pages)
Drought stress is one of the major yield affecting factor for pepper plant. The effects of PGPRs were analyzed in relation with drought resistance. The PGPRs inoculated pepper plants tolerate the drought stress and survived as compared to non-inoculated pepper plants that died after 15 days of drought stress. Variations in protein and RNA accumulation patterns of inoculated and noninoculated pepper plants subjected to drought conditions for 10 days were confirmed by two dimensional... -
Regulation of Pathogenesis by Light in Cercospora zeae-maydis: An Updated Perspective
한국식물병리학회 The Plant Pathology Journal 7 Pages
한국식물병리학회 The Plant Pathology Journal 2011, 27권 2호 1 103-109 (7 pages)
The fungal genus Cercospora is one of the most ubiquitous groups of plant pathogenic fungi, and gray leaf spot caused by C. zeae-maydis is one of the most widespread and damaging foliar diseases of maize in the world. While light has been implicated as a critical environmental regulator of pathogenesis in C. zeae-maydis, the relationship between light and the development of disease is not fully understood. Recent discoveries have provided new insights into how light influences pathogenesis and... -
식물바이러스 면역반응 최신 연구 동향 및 전망
김남연, 홍진성, 정래동 한국식물병리학회 식물병연구 17 Pages
한국식물병리학회 식물병연구 2018, 24권 1호 2 9-25 (17 pages)
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A Study on Development of Improvement Guidelines of Smart Accessibility for the Disabled
Woochun Jun 인문사회과학기술융합학회 예술인문사회융합멀티미디어논문지 12 Pages
인문사회과학기술융합학회 예술인문사회융합멀티미디어논문지 2015, 제 5권 제 5호 6 47-58 (12 pages)
In current knowledge and information society, digital divide is a big concern for all. That is, the disabled have some troubles to enjoy their daily life. Recently, numerous ICT and smart devices are available for the disabled as well as the non-disabled. For the disabled, improving smart accessibility is very important to live in smart environment. The purpose of this paper is to present some practical guidelines for improving smart accessibility for the disabled. The improvement guidelines are... -
개구리 망막에 있는 광수용세포의 미세구조
김진숙, 전진석, Kim. Jin-Suk, Jeon. Jin-Seok 한국현미경학회 한국전자현미경학회지 9 Pages
한국현미경학회 한국전자현미경학회지 1995, Vol.25 No.4 115-123 (9 pages)


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