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전체 선택해제
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본문검색 결과만 보기
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Photochemical Formation of 3-Methoxycyclohex-2-en-1-ones from 1,3-Cyclohexanedione and 2-Allyl-3-hydroxycyclohex-2-en-1-one in Methanol in the Presence of Quinones
Kim. Sung-Sik, Chang. Ji-Ae, Kim. Ae-Rhan, Mah. Yoon-Jung, Kim. Hyun-Jin, Kang. Chan 한국광과학회 Journal of photoscience: an international journal officail organ of the Korean Society of Photoscien 4 Pages
한국광과학회 Journal of photoscience: an international journal officail organ of the Korean Society of Photoscien 2000, Vol.7 No.3 111-114 (4 pages)
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Photoaddition Reactions of 1 , 4 Diphenylbut -1-EN-3-YNE to Quinones
Kim. Sung-Sik, Kim. Ae-Rhan, Chang. Ji-Ae, Mah. Yoon-Jung, Lim. Jin-Sun, Yoo. Dong-Jin, Jeon. Il-Cheol 한국광과학회 Journal of photoscience: an international journal officail organ of the Korean Society of Photoscien 6 Pages
한국광과학회 Journal of photoscience: an international journal officail organ of the Korean Society of Photoscien 1999, Vol.6 No.1 7-12 (6 pages)
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The Synthesis of Novel Mono(alkoxy)-, Tris(thio)- and Tetrakis(thio)-Substituted Quinones from the Reactions of p-Chloranil with Various S-Nucleophiles
Ibis. Cemil, Yildiz. Mahmut, Sayil. Cigdem 대한화학회 Bulletin of the Korean Chemical Society 6 Pages
대한화학회 Bulletin of the Korean Chemical Society 2009, Vol.30 No.10 2381-2386 (6 pages)
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Synthesis of Heterocyclic Quinones Containing Bridgehead Nitrogen Atom from 2-Aminonaphtho[2,3-d]thiazole-4,9-dione
Fandy. Ragab F. 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 4 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2000, Vol.23 No.5 446-449 (4 pages)
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PHOTOCHEMICAL FORMATION OF ISOMERIC QUINONE METHIDES FROM o-QUINONES AND ONE-WAY ISOMERIZATION
Kim. Ae-Rhan 한국광과학회 Journal of photoscience: an international journal officail organ of the Korean Society of Photoscien 4 Pages
한국광과학회 Journal of photoscience: an international journal officail organ of the Korean Society of Photoscien 1997, Vol.4 No.2 49-52 (4 pages)
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PHOTOADDITION REACTIONS OF 1,4-DIPHENYLBUT-1-EN-3-YNE TO p-QUINONES
Kim. Sung-Sik, So. Mi-Hyun 한국광과학회 Journal of photoscience: an international journal officail organ of the Korean Society of Photoscien 4 Pages
한국광과학회 Journal of photoscience: an international journal officail organ of the Korean Society of Photoscien 1996, Vol.3 No.2 61-64 (4 pages)
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Pulsed-wave Doppler ultrasonographic evaluation of hepatic vein in dogs with tricuspid regurgitation
Jaehwan Kim, Soyoung Kim, Kidong Eom 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 1호 10 73-79 (7 pages)
This study was performed to identify the relationships between hepatic vein (HV) measurements, including flow velocity and waveform, using pulsed-wave (PW) Doppler ultrasonography, and the severity of tricuspid regurgitation (TR) in dogs. The study included 22 dogs with TR and 7 healthy dogs. The TR group was subdivided into 3 groups according to TR jet profile obtained by echocardiography. The hepatic venous waveform was obtained and classified into 3 types. A variety of HV measurements,... -
Tissue Doppler and strain imaging of left ventricle in Beagle dogs with iatrogenic hypercortisolism
Heejin Oui, Sunghoon Jeon, Gahyun Lee, Seungjo Park, Kyoung-Oh Cho, Jihye Choi 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 3호 14 357-365 (9 pages)
Changes in radial and longitudinal left ventricular (LV) function were investigated in beagles with iatrogenic hypercortisolism. A total of 11 normal dogs were used, and 2 mg/kg prednisone was administered per oral q12 h for 28 days to 7 out of 11 dogs to induce iatrogenic hypercortisolism. Body weight, blood pressure, conventional echocardiography and tissue Doppler imaging (TDI) of normal and iatrogenic hypercortisolism groups were conducted. The myocardial wall velocity of the LV was measured... -
Pulsed tissue Doppler imaging of the left ventricular septal mitral annulus in healthy dogs
Jihye Choi, Hyunwook Kim, Junghee Yoon* 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2013, 제 14권 제 1호 12 85-90 (6 pages)
This study evaluated pulsed TDI variables including the isovolumic time interval and duration of the major wave in a population of large healthy dogs. Longitudinal myocardial motion at the septal mitral annulus was evaluated with pulsed TDI in 45 healthy adult dogs. Maximal myocardial velocities, isovolumic time intervals, and duration of the myocardial waves were measured. The correlation between time intervals and velocity variables was also investigated. The mean maximal systolic velocity was... -
Evaluation of plasma N-terminal pro-brain natriuretic peptide and troponin I concentrations in dogs with congenital ventricular outflow tract stenosis
Gye-dong Kim , Sang-il Suh , In-chul Park , Changbaig Hyun , 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 5 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2016, 제 56권 제 4호 4 223-227 (5 pages)
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Original Article : Usefulness of ultrasound contrast media for cardiac output measurement with echocardiography
Je Woong Yun , Seong Chan Yeon , Hee Chun Lee 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 6 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2015, 제 55권 제 1호 7 47-52 (6 pages)
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Effects of Free Anthraquinones Extract from the Rhubarb on Cell Proliferation and Accumulation of Extracellular Matrix in High Glucose Cultured-Mesangial Cells
JianyunWang, HuiFang, BingzhengDong, DongdongWang, YanLi, XiaoChen, LijuanChen, TongWei, QunliWei 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.6 2 485-489 (5 pages)
Diabetic nephropathy (DN) is the leading cause of end-stage failure of the kidney, but the efficacy of currently available strategies for the prevention of DN remains unsatisfactory. In this study, we investigated the effects of free anthraquinones (FARs) extract, which was extracted from the rhubarb and purified by macroporous resin DM130 with gradient mixtures of ethanol/water as the lelution solvents, in high glucose-cultured glomerular mesangial cells (MCs). The cell proliferation was... -
5,8-Dimethoxy-2-Nonylamino-Naphthalene-1,4-DioneInhibitsVascular Smooth Muscle Cell Proliferation by Blocking Autophosphorylation of PDGF-Receptor β
YohanKim, Jung-JinLee, Sang-GilLee, Sang-HyukJung, Joo-HuiHan, SoYoungYang, , EunjuYun, Gyu-YongSong, Chang-SeonMyung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.3 4 203-208 (6 pages)
As the abnormal proliferation of vascular smooth muscle cells (VSMCs) plays a critical role in the development of atherosclerosis and vascular restenosis, a candidate drug with antiproliferative properties is needed. We investigated the antiproliferative action and underlying mechanism of a newly synthesized naphthoquinone derivative, 5,8-dimethoxy-2-nonylamino-naphthalene-1,4-dione (2-nonylamino- DMNQ), using VSMCs treated with platelet-derived growth factor (PDGF). 2-Nonylamino-DMNQ inhibited... -
Ischemia/reperfusion Lung Injury Increases Serum Ferritin and Heme Oxygenase-1 in Rats
Yoon-YubPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.3 7 181-187 (7 pages)
Intestinal ischemia/reperfusion (I/R) is one of common causes of acute lung injury (ALI). Early and accurate diagnosis of patients who are like to develop serious acute respiratory distress syndrome (ARDS) would give a therapeutic advantage. Ferritin and heme oxygenase-1 (HO-1) are increased by oxidative stress and are potential candidates as a predictive biomarker of ARDS. However, the mechanisms responsible for the increases of ferritin and HO-1, and their relationship to ALI, are unclear. In... -
Induction of Heme Oxygenase-1 by Traditional Herb Mix Extract Improves MKN-74 Cell Survival and Reduces Stomach Bleeding in Rats by Ethanol and Aspirin in vivo
YoungJinKang, HyungSukMoon, HyeJungKim, HanGeukSeo, JaeHeunLee, KiChurlChang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.2 4 65-70 (6 pages)
Chinese herb medicines have traditionally been used to treat or alleviate the symptom of various diseases. The rationale for use of certain herbs to certain disorder is now getting unveiled by modern technology. In the present study, we investigated whether herb mix extract (HMX), which is alleged to be useful for gastric ulcer, protects stomach from oxidative stress. Rats were allowed to normal diet with and without HMX (1, 5, 10 mg/kg) for 30 days. To induce gastric ulcer, ethanol (75%, 1.5... -
Differential Inhibition of MPP+- or 6-Hydroxydopamine-induced Cell Viability Loss in PC12 Cells by Trifluoperazine and W-7
ChungSooLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.4 9 247-252 (6 pages)
The present study assessed the effect of calmodulin antagonists trifluoperazine and W-7 against the cytotoxicity of MPP and 6-hydroxydopamine (6-OHDA) in relation to the mitochondrial dysfunction and cell death in PC12 cells. Trifluoperazine (an inhibitor of the mitochondrial permeability transition and calmodulin antagonist) and W-7 (a specific calmodulin antagonist) significantly attenuated the MPP- induced cell viability loss in PC12 cells with a maximum inhibition at 0.5∼1μM;... -
Effects of Dopamine on Intracellular pH in Opossum Kidney Cells
KyungWooKang, YungKyuKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.3 11 187-191 (5 pages)
Na/H exchanger (NHE) has a critical role in regulation of intracellular pH (pHi) in the renal proximal tubular cells. It has recently been shown that dopamine inhibits NHE in the renal proximal tubules. Nevertheless, there is a dearth of information on the effects of long-term (chronic) dopamine treatment on NHE activities. This study was performed to elucidate the pHi regulatory mechanisms during the chronic dopamine treatments in renal proximal tubular OK cells. The resting pHi... -
Tissue-Specific Regulation of Angiotensinogen and Angiotensin II Receptor Gene Expression in Deoxycorticosterone Acetate-Salt Hypertensive Rats
JongUnLeeMiRaAn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.3 9 315-320 (6 pages)
Molecular regulation of the renin-angiotensin system (RAS) was investigated in deoxycorticosterone acetate (DOCA)-salt hypertension. The expression of renin, angiotensinogen and angiotensin II receptor genes in the kidney and liver was determined by Northern blot analysis in rats which were made DOCA-salt hypertensive over the period of 2 or 4 weeks. Along with the hypertension, renin mRNA was decreased in the remnant kidney. The expression of angiotensinogen gene was not significantly altered... -
Effect of the Inhibition of PLA2 on Oxidative Lung Injury Induced by Interleukin-1
YoungManLee, HyunGugCho, Yoon-YubPark, Jong-KiKim, YoonJeongLee, Won-HarkPark, TeoanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.5 10 617-628 (12 pages)
In order to understand the pathogenetic mechanism of adult respiratory distress syndrome (ARDS), the role of phospholipase A2 (PLA2) in association with oxidative stress was investigated in rats. Interleukin-1 (IL-1, 50 ㄍg/rat) was used to induce acute lung injury by neutrophilic respiratory burst. Five hours after IL-1 insufflation into trachea, microvascular integrity was disrupted, and protein leakage into the alveolar lumen was followed. An infiltration of neutrophils was... -
Effect of Bromocriptine on 6-Hydroxydopamine-induced Lipid Peroxidation and Cytotoxicity in vitro and in vivo
YongSikKim, SunghoMaeng, ChanWoongPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.5 4 565-572 (8 pages)
The present study was to evaluate the protective effects of bromocriptine, which is known as D2 dopamine receptor agonist and used for the treatment of patients with Parkinson's disease (PD), on 6-hydroxydopamine (6-OHDA)-induced neurotoxicity in vitro and in vivo. Lipid peroxidation product (malondialdehyde; MDA) produced by the administration of 6-OHDA was profoundly reduced following the treatment of bromocriptine in a dose-dependent manner in rabbit brain homogenate. Quinone formation by... -
대뇌 피질 신경 세포 일차 배양에서 6-hydroxydopamine에 의한 신경세포사멸의 특성
정재훈, 강효정, 손성향, 정영기, 곽병주, 노재성 대한신경정신의학회 신경정신의학 10 Pages
대한신경정신의학회 신경정신의학 2000, 제 39권 제 3호 17 656-665 (10 pages)
연구목적： 본 연구는 생쥐 태자 대뇌 피질 세포 일차 배양에서 파킨슨씨병의 동물 모델을 만드는데 사용되는 신경독 성 물질인 6-hydroxydopamine(6-OHDA)에 의한 신경세포 사멸의 특성을 관찰한 것이다. 방 법： 생쥐태자의 신경세포를 배양하여 6-OHDA를 처리하고 이와 더불어 여러가지 신경세포 사멸에 영향을 주 는 물질을 투여하여 신경세포의 사멸을 정량적으로 분석하고 형태학적 분석을 전자현미경을 통하여 관찰하 였다 결 과： 배양한 신경세포에 6-OHDA를 처리하면 투여 양에 비례하여 신경세포의 사멸이 증가하며 50μM 6-... -
상악동 골이식과 임플란트 식립의 예후에 미치는 영향 평가
김영균, 김진아 대한치과이식임플란트학회 Journal of Dental Implant Research 7 Pages
대한치과이식임플란트학회 Journal of Dental Implant Research 2012, 제 31권 2호 1 31-37 (7 pages)
상악 구치부는 대부분의 골질이 type III, IV로 이루어져 있고 잔존골량이 부족한 경우가 많기 때문에 임플란트의 성공률이 낮은 것으로 알려져 있다1). 오랜 기간 무치악으로 방치되는 경우 상악동 의 함기화와 함께 잔존골의 흡수가 일어나 임플란트 식립을 위한 절대적인 골량이 부족해진다. 이를 해결하기 위한 첫 번째 시도가 1980년에 Boyne에 의해 소개되었는데 Caldwell-Luc 방식으로 상악동에 접근하고 이식재로 자가 망상골인 장골을 사용하였다2). 이 후 많은 임상가들에 의해 다양한 시도가 있었고, 1986년 Tatum3)이 측방...
