자료유형
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- 대한수의학회(7)
- 대한생리학회-대한약리학회(6)
- 대한약리학회(3)
- 한국식물병리학회(3)
- 대한신경정신의학회(2)
- 대한생리학회(1)
- 대한치과교정학회(1)
- 한국미생물생명공학회(1)
- 한국자원리싸이클링학회(1)
- 한국탄소학회(1)
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- THE KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY(6)
- JOURNAL OF VETERINARY SCIENCE(4)
- KOREAN JOURNAL OF VETERINARY RESEARCH(구 대한수의학회지)(3)
- 대한약리학잡지(3)
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- 대한생리학회지(1)
- 자원리싸이클링 : 한국자원리싸이클링학회지(1)
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Optimum Conditions for the Formation of Acetoin as a Precursor of Tetramethylpyrazine during the Citrate Fermentation by Lactococcus lactis subsp. lactis biovar. diacetilactis FC1
Kim. Kyoung-Heon, Lee. Hyong-Joo 한국미생물생명공학회 Journal of microbiology and biotechnology 5 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 1991, Vol.1 No.3 202-206 (5 pages)
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Inhibition of β-amyloid1-40 Peptide Aggregation and Neurotoxicity by Citrate
YongHoonPark, Young-JinKim, IlHongSon, HyunDukYang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.4 2 273-279 (7 pages)
from 84.6 to 93.8% as compared with the AՂ1-40 aggregates alone treated cells (65.3%). Furthermore, Hoechst 33342 staining showed that citrate (1.0 mM) suppressed AՂ1-40 aggregates-induced apoptosis in the cells. This study suggests that citrate can inhibit AՂ1-40 aggregation and protect neurons from the apoptotic effects of AՂ1-40 aggregates. Accordingly, our findings suggest that citrate administration should be viewed as a novel neuroprotective strategy for AD. -
Immunohistochemical evaluation of the goat forestomach during prenatal development
Angela Garcia, Javier Masot, Antonio Franco, Antonio Gazquez, Eloy Redondo, * 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 1호 4 35-43 (9 pages)
Here we report the detection and distribution of synaptophysin (SPY), non-neuronal enolase (NNE), glial fibrillary acidic protein (GFAP), vimentin (VIM), neuropeptide Y (NPY), and vasoactive intestinal peptide (VIP) expression in the goat forestomach during prenatal development. A total of 140 embryos and fetuses were examined to evaluate protein expression from the first stage of prenatal life until birth. In all cases, SPY immunoreactivity was detected at 53 days gestation in the lamina... -
Immunohistochemical Localization of Bcl-2 in the Spinal Cords of Rats with Experimental Autoimmune Encephalomyelitis
Chang-Jong Moon, Yong-Duk Lee and Tae-Kyun Shin 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 4호 5 279-283 (5 pages)
We examined the localization of the anti-apoptotic molecule Bcl-2 in the spinal cords of Lewis rats with experimental autoimmune encephalomyelitis (EAE). Western blot analysis showed that Bcl-2 was constitutively expressed in normal spinal cords, and weakly increased in response to complete Freund's adjuvant(CFA) immunization. In EAE, with infiltration of inflammatory cells into spinal cords, Bcl-2 declined during the peak stage and further decreased during the recovery stage.... -
Enhanced expression of constitutive and inducible forms of nitric oxide synthase in autoimmune encephalomyelitis
Seungjoon Kim, Changjong Moon, Myung Bok Wie, Hyungmin Kim, Naoyuki Tanuma, Yoh Matsumoto, Taekyun Shin 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2000, 제 1권 제 1호 2 11-17 (7 pages)
To elucidate the role of nitric oxide synthase (NOS) in the pathogenesis of experimental autoimmune encephalomyelitis (EAE), we analyzed the expression of constitutive neuronal NOS (nNOS), endothelial NOS (eNOS), and inducible NOS (iNOS) in the spinal cords of rats with EAE. We further examined the structural interaction between apoptotic cells and spinal cord cells including neurons and astrocytes, which are potent cell types of nitric oxide (NO) production in the brain. Western blot analysis... -
Original Article : Virulence factors, antimicrobial resistance patterns, and genetic characteristics of hydrogen sulfide-producing Escherichia coli isolated from swine
Hyun Eui Park , Min Kyoung Shin , Hong Tae Park , Seung Won Shin , Myunghwan Jung , Young Bin Im , Han Sang Yoo 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 7 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2015, 제 55권 제 3호 7 191-197 (7 pages)
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Original Article : Chemopreventive effects of garlic and mugwort mixture extract on Helicobacter pylori-associated mouse gastric carcinogenesis
So Young Youm , Tae Wang Kim , Sang Kyung Shin , Heon Sang Jeong , Jong Koo Kang , Tae Myoung Kim , Kil Ho Kim , Byeong 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 7 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2014, 제 54권 제 3호 7 171-177 (7 pages)
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Isolation and characterization of fowl adenovirus serotype 4 from chickens with hydropericardium syndrome in Korea
Hong Su Park , Il Soo Lim , Sang Kyu Kim , Toh Kyung Kim , Sang Geon Yeo 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 8 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2011, 제 51권 제 3호 5 209-216 (8 pages)
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NecroX-5 protects mitochondrial oxidative phosphorylation capacity and preserves PGC1α expression levels during hypoxia/ reoxygenation injury
VuThiThu, HyoungKyuKim, LeThanhLong, BayalagmaaNyamaa, In-SungSong, ToThanhThuy, NguyenQuangHuy, JubertMarquez, SoonHaKim, NariKim, KyungS 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.2 9 201-211 (11 pages)
system. Proteomic analysis was performed using liquid chromatography-mass spectrometry (LC-MS) and non-labeling peptide count protein quantification. Real-time PCR, western blot, citrate synthases and mitochondrial complex activity assays were then performed to assess heart function. Treatment with NecroX-5 during hypoxia significantly preserved electron transport chain proteins involved in oxidative phosphorylation and metabolic functions. NecroX-5 also improved mitochondrial complex I, II, and... -
Epigallocatechin-3-Gallate (EGCG) Attenuates Traumatic Brain Injury by Inhibition of Edema Formation and Oxidative Stress
BoZhang, BingWang, ShuhuaCao, YongqiangWang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.6 3 491-497 (7 pages)
Traumatic brain injury (TBI) is a major cause of mortality and long-term disability, which can decrease quality of life. In spite of numerous studies suggesting that Epigallocatechin-3- gallate (EGCG) has been used as a therapeutic agent for a broad range of disorders, the effect of EGCG on TBI remains unknown. In this study, a weight drop model was established to evaluate the therapeutic potential of EGCG on TBI. Rats were administered with 100 mg/kg EGCG or PBS intraperitoneally. At different... -
The Critical Roles of Zinc: Beyond Impact on Myocardial Signaling
SungRyulLee, SuJinNoh, JuliusRyanPronto, YuJeongJeong, HyoungKyuKim, InSungSong, ZhelongXu, HyogYoungKwon, SeChanKang, Eun-HwaSohn, KyungS 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.5 1 389-400 (12 pages)
Zinc has been considered as a vital constituent of proteins, including enzymes. Mobile reactive zinc (Zn2+) is the key form of zinc involved in signal transductions, which are mainly driven by its binding to proteins or the release of zinc from proteins, possibly via a redox switch. There has been growing evidence of zinc’s critical role in cell signaling, due to its flexible coordination geometry and rapid shifts in protein conformation to perform biological reactions. The importance and... -
Effect of Defibrotide on Rat Reflux Esophagitis
HyoungKiKim, SooRanChoi, SangJinChoi, MyungSupChio, YongKyooShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.6 5 319-328 (10 pages)
This study was aimed at evaluating the effect of defibrotide on the development of the surgically induced reflux esophagitis, on gastric secretion, lipid peroxidation, polymorphonuclear leukocytes (PMNs) accumulation, polymorphonuclear leukocytes adherence, superoxide anion and hydrogen peroxide production in PMNs, scavenge of hydroxyl radical and hydrogen peroxide, cytokine (interleukin-1β, tumor necrosis factor-α) production in blood, and intracellular calcium mobilization in PMNs.... -
Prevention of Diabetes Using Adenoviral Mediated Hepatocyte Growth Factor Gene Transfer in Mice
Hye-JeongLee, Hyun-JeongKim, Mee-SookRoh, Jae-IkLee, Sung-WonLee, Dong-SikJung, Duk-KyuKim, Mi-KyoungPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.5 3 261-266 (6 pages)
Type 1 diabetes is an organ-specific autoimmune disease caused by the cytotoxic T cells-mediated destruction of the insulin-producing beta cells in the Langerhans pancreatic islets. Hepatocyte growth factor (HGF) is a potent mitogen and a promoter of proliferation of insulin producing beta cells of pancreatic islets. To study the role of HGF via viral vector in the development of streptozotocin (STZ)-induced diabetes in mice, we have developed an adenoviral vector genetically engineered to carry... -
반복적 스트레스가 흰쥐의 Opioid성 신경전달에 미치는 영향
사공정규, 이광헌, 구본훈, 김진성, 이종범, 하정희 대한신경정신의학회 신경정신의학 9 Pages
대한신경정신의학회 신경정신의학 1999, 제 38권 제 3호 18 638-646 (9 pages)
연구목적： 반복적인 스트레스에 노출된 실험동물에서 opioid성 신경전달의 변화양상을 검색하고 내인성 opioid peptide 의 변화양상을 알아보기 위하여 본 연구를 시행하였다. 방 법： 본 연구에서는 웅성 흰쥐에게 하루 2시간, 2주간의 반복적인 부동화 스트레스를 가한 후 뇌의 각 부위에서 opioid 수용체의 mu-, delta- 및 kappa- 아형의 최대결합력 및 친화력의 변화 양상을 관찰하였다. 결 과： 반복적 부동화 스트레스 노출군에서는 대조군에 비하여 delta-아형 수용체의 수가 시상하부(hypothalamus) 및 선조체(striatum)에서... -
소 부신수실 크롬친화성 세포에서 Nicotine의 장기간 자극으로 유발된 Proenkephalin A mRNA의 증가 및 [Met5]-enkephalin의 분비 증가가 Lipoxygenase 경로에 의해 매개됨
서홍원(Hong-Won Suh), 김영희(Yung-Hi Kim) 대한약리학회 대한약리학잡지 8 Pages
대한약리학회 대한약리학잡지 1993, 제 29권 제 2호 9 237-244 (8 pages)
소 부신수실 크롬친화성 세포(BAMC)에서 [Met5]-enkephalin (ME)의 분비와 Proenkephalin A (proENK) mRNA의 함량에 대한 nicotine의 영향과 이에 대한 indomethacin, nordihydroguaiaretic acid(NDGA) 및 captopril의 작용을 연구하였다. 10 uM Nicotine으로 BAMC 세포를 장기간 자극시 proENK mRNA의 함량과 배양액으로의 ME 분비가 유의하게 증가하였다. BAMC 세포를 NDGA(lipoxygenase 억제제, 10 uM), indomethacin (cyclooxygenase 억제제), captopril (angiotensin 변환효소 억제제)만으로 처리시에는 ME 분비와 proENK mRNA의... -
Interaction between Renin-Angiotensin and Endothelium-Derived Nitric Oxide Systems in Two-Kidney, One Clip Hypertensive Rats
Ahn, Hyun-Tack, Nah, Kook-Joo, Lee, Jong-Un 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1996, 제 30권 제 1호 4 33-42 (10 pages)
The present study was aimed to investigate the role of endothelium-derived nitric oxide (NO) in the control of renin release and to examine if NO is implicated in the development of two-kidney, one clip (2K1C) hypertension. Male Sprague-Dawley rats (150 ~ 200 g) were constricted at the left renal artery. They were then supplemented with NG-nitro-L-arginine methyl ester (L-NAME, 5mg/100 mL) or with L-arginine hydrochloride (400 mg/100 mL) in the drinking water. The control group was supplied... -
Proteomic Changes in the Sound Vibration-Treated Arabidopsis thaliana Facilitates Defense Response during Botrytis cinerea Infection
Ritesh Ghosh, Bosung Choi, Young Sang Kwon, Tufail Bashir, Dong-Won Bae, Hanhong Bae 한국식물병리학회 The Plant Pathology Journal 14 Pages
한국식물병리학회 The Plant Pathology Journal 2019, 35권 6호 7 609-622 (14 pages)
Sound vibration (SV) treatment can trigger various molecular and physiological changes in plants. Previously, we showed that pre-exposure of Arabidopsis plants to SV boosts its defense response against Botrytis cinerea fungus. The present study was aimed to investigate the changes in the proteome states in the SV-treated Arabidopsis during disease progression. Proteomics analysis identified several upregulated proteins in the SVinfected plants (i.e., SV-treated plants carrying Botrytis... -
$LiCoO_2$의 재합성시(再合成時) 전극특성(電極特性)에 미치는 탄소(炭素)의 영향(影響)
이철경, 박정길, 손정수, Lee. Churl-Kyoung, Park. Jeong-Kil, Sohn. Jeong-Soo 한국자원리싸이클링학회 資源리싸이클링 : 한국자원리싸이클링학회지 10 Pages
한국자원리싸이클링학회 資源리싸이클링 : 한국자원리싸이클링학회지 2007, Vol.16 No.6 10-19 (10 pages)
침출액으로부터 양극활물질을 재합성하는 공정으로 citrate precursor combustion법을 제안하고 가능성을 확인하였다. 기존의 전극제조 공정에서는 활물질인 $LiCoO_2$와 첨가제인 탄소의 비중 및 크기 차이로 균일한 혼합이 이루어지지 않으므로 충방전 용량이 이론용량에 비하여 매우 낮고 또한 싸이클이 반복될수록 용량이 크게 감소하는 경향을 보였다. 본 연구에서는 합성된 $LiCoO_2$ 전극특성을 향상시키는 일환으로 합성공정의 개선을 통하여 초미립 $LiCoO_2$을 합성하였으며, 탄소 첨가시 혼합법의 개선에 의하여 우수한 충방전... -
Calcium homeostasis in diabetes mellitus
Changhwan Ahn, Ji-Houn Kang, Eui-Bae Jeung 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 3호 1 261-266 (6 pages)
Diabetes mellitus (DM) is becoming a lifestyle-related pandemic disease. Diabetic patients frequently develop electrolyte disorders, especially diabetic ketoacidosis or nonketotic hyperglycemic hyperosmolar syndrome. Such patients show characteristic potassium, magnesium, phosphate, and calcium depletion. In this review, we discuss a homeostatic mechanism that links calcium and DM. We also provide a synthesis of the evidence in favor or against this linking mechanism by presenting recent... -
EFFECTS OF NITRIC OXIDE SYNTHASE INHIBITORS ON OSTEOCLAST-LIKE CELL FORMATION
Seung-Kyu Ahn, Jung-Kun Kim, Kyung-Suk Cha 대한치과교정학회 The Korean Journal of Orthodontics 8 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1995, 제 25권 제 6호 7 715-722 (8 pages)
Orthodontic tooth movement in response to orthodontic force results from actions of osteoclasts and osteoblasts in the cell level. Convincing evidence has now been provided to support the view that osteoclasts are derived from mononuclear cells that originate in the bone marrow or other hematopoietic organs and they migrate to the bones via vascular routes. Nitric oxide(NO), which accounts for the biological properties of endothelium-derived relaxmg factor(EDRF), is the endogenous stimulator of... -
흰쥐에서 급성 스트레스 유발 불안반응의 해소에 대한 신경교세포 말초성 벤조다이아제핀 수용체의 매개작용
김영욱, 박형배, 이종범, 김진성, 정성덕, 하정희, 송창진 대한신경정신의학회 신경정신의학 9 Pages
대한신경정신의학회 신경정신의학 1999, 제 38권 제 3호 19 647-655 (9 pages)
연구목적： 말초성 벤조다이아제핀 수용체가 스트레스로 유발된 불안반응에서의 불안해소작용을 알아보기 위해 흰쥐 에 급성 부동화(immobilization) 스트레스를 부하하여 유도된 불안반응에서 뇌조직중의 말초성 벤조다이아제핀 수용체의 매개작용을 검색하고자 본 연구를 시행하였다. 방 법： 흰쥐에 급성 부동화 스트레스를 가한 후 실험동물의 불안도를 elevated plus maze를 통하여 검정하고 말 초성 벤조다이아제핀 수용체의 변화를 수용체 결합반응을 통하여 검색하여 대조군과 비교했고, 말초성 벤조다이 아제핀 수용체 효현제 및... -
백서태자두개관에서 분리한 세포의 약리학적 및 생화학적 특성에 관한연구
한남수(Nam-Soo Han), 정동균(Dong-Kyun Cheong), 모리 마사카주(Masakazu，Mori) 대한약리학회 대한약리학잡지 16 Pages
대한약리학회 대한약리학잡지 1990, 제 26권 제 2호 12 193-208 (16 pages)
Transforming growth factor β(TGF-β)는 많은 세포의 증식, 분화 및 여러가지 세포기능에 대해 다양한 조절기능을 갖고 있는 multifunctional polypeptide로 알려져 있다. TGF-β는 골기질에 상당량 존재하며 골조직 대사에 대해 광범위한 영향을 나타낸다. 여러가지 연구결과에 의해 기질과 연관된 TGF-β는 골세포 자체의 산물로 여겨지고 있으나 골조직세포군중 어느종류의 세포가 TGF-β를 형성하는지에 대해서는 논란이 되고 있다. 본 연구는 TGF-β를 형성하는 골조직세포를 규명하고 TGF-β가 서로 다른 세포들에 미치는 영향을... -
흰쥐의 Carrageenin 유발 늑막염과 Croton oil 유발 육아종양에 미치는 Cyclobuxine D의 영향
이종화(Jong-Hwoa Lee), 박영현(Young-Hyun Park), 조병헌(Byung-Heon Cho), 김유재(Yu-Jae Kim), 김종배(Jong-Bae Kim), 김정목(Chung-Mok Kim), 김천숙(Chun-Sook K 대한약리학회 대한약리학잡지 7 Pages
대한약리학회 대한약리학잡지 1987, 제 23권 제 2호 10 151-157 (7 pages)
Steroidal alkaloid인 cyclobuxine D의 carrageenin으로 유발한 늑막염과 croton oil로 유발한 육아종양에 대한 영향을 관찰하고 그 작용을 aspirin, dexamethasone과 hydrocortisone의 작용과 비교하였다. Carrageenin으로 유발한 늑막염에서 혈장 삼출정도는 pontamine sky blue을 정맥으로 투여하여 20분 동안 늑막염 삼출물로 삼출되어 나오는 양으로 측정하였다. Cyclobuxine D는 용량적으로 삼출물의 양과 20분 동안 삼출되는 pontamine sky blue의 양을 감소시켰다. Cyclooxygenase 억제제인 aspirin과 phospholipase A2를...
