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전체 선택해제
총 762건 검색
본문검색 결과만 보기
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Mathematical Modeling and Simulation of spread of FMD and HPAI in the Republic of Korea
Hachung Yoon, Chang Hyung Lee, Pil Won Kim, Hyo Jeong Lee, Woo-seog Jeong, Jida Choi, Yong Myung Kang, Jee Hye Kim, Chung Sik Jung, Hong 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 춘계학술심포지움 47 107-108 (2 pages)
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A quantitative modeling approach to estimate the risks posed by the smuggled animal products contaminated with Foot-and-Mouth Disease (FMD) virus
KiOkHong, GilHongLee, SonIlPak 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 9 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2005, 제 45권 제 2호 12 223-231 (9 pages)
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Prediction of pharmacokinetics and drug-drug interaction potential using physiologically based pharmacokinetic (PBPK) modeling approach: A case study of caffeine and ciprofloxacin
Min-HoPark, Seok-HoShin, Jin-JuByeon, Gwan-HoLee, Byung-YongYu, YoungG.Shin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.1 13 107-115 (9 pages)
of PBPK modeling and simulation for this study. Compared to caffeine, the PBPK modeling for ciprofloxacin was challenging due to several factors including solubility, permeability, clearance and tissue distribution etc. Therefore, intensive parameter sensitivity analysis (PSA) was conducted to optimize the PBPK model for ciprofloxacin. Overall, the increase in Cmax of caffeine by ciprofloxacin was not significant. However, the increase in AUC was observed and was proportional to the administered... -
Spatial reproducibility of complex fractionated atrial electrogram depending on the direction and configuration of bipolar electrodes: an in-silico modeling study
Jun-SeopSong, Young-SeonLee, MinkiHwang, Jung-KeeLee, ChangyongLi, BoyoungJoung, Moon-HyoungLee, EunBoShim, Hui-NamPak 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.5 8 507-514 (8 pages)
Although 3D-complex fractionated atrial electrogram (CFAE) mapping is useful in radiofrequency catheter ablation for persistent atrial fibrillation (AF), the directions and configuration of the bipolar electrodes may affect the electrogram. This study aimed to compare the spatial reproducibility of CFAE by changing the catheter orientations and electrode distance in an in -silico left atrium (LA). We conducted this study by importing the heart CT image of a patient with AF into a 3D-homogeneous... -
Modeling of the Parathyroid Hormone Response after Calcium Intake in Healthy Subjects
JaeEunAhn, SangilJeon, JongtaeLee, SeunghoonHan, Dong-SeokYim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.3 4 217-223 (7 pages)
Plasma ionized calcium (Ca2+) concentrations are tightly regulated in the body and maintained within a narrow range; thus it is challenging to quantify calcium absorption under normal physiologic conditions. This study aimed to develop a mechanistic model for the parathyroid hormone (PTH) response after calcium intake and indirectly compare the difference in oral calcium absorption from PTH responses. PTH and Ca2+ concentrations were collected from 24 subjects from a clinical trial performed to... -
Modeling of Arrhythmogenic Automaticity Induced by Stretch in Rat Atrial Myocytes
JaeBoumYoum, ChaeHunLeem, YinHuaZhang, NariKim, JinHan, YungE.Earm 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.5 8 267-274 (8 pages)
Since first discovered in chick skeletal muscles, stretch-activated channels (SACs) have been proposed as a probable mechano-transducer of the mechanical stimulus at the cellular level. Channel properties have been studied in both the single-channel and the whole-cell level. There is growing evidence to indicate that major stretch-induced changes in electrical activity are mediated by activation of these channels. We aimed to investigate the mechanism of stretch-induced automaticity by... -
The Influence of Maternal Factors and Child Self-regulation on Peer Initiative: A Structural Equation Modeling Approach
Seonhyung Choi, Sunhee Kim 환태평양유아교육연구학회 Asia-Pacific journal of research in early childhood education 24 Pages
환태평양유아교육연구학회 Asia-Pacific journal of research in early childhood education 2021, Vol.15 No.3 1 1-24 (24 pages)
or unfriendly. This study used structural equation modeling to examine the contributions of mother’s coaching competence, parenting behavior, and child self-regulation to peer initiative. Participants comprised mothers of children aged 3 to 5 years (n = 343) in Korea and their teachers (n = 39). Structural equation modeling indicated that the relationship between mothers’ coaching competence and friendly peer initiative was fully mediated by maternal affection and child self-regulation.... -
The Impact of Sample Size on Three-Level Quadratic Cross-Classified Multiple Membership Growth Curve Modeling Estimation
정혜원(Chung Hyewon), 전현정(Jeon Hyeonjeong), 박소영(Park Soyoung) 한국교육학회 교육학연구 22 Pages
한국교육학회 교육학연구 2022, 60권 7호 1 1-22 (22 pages)
a minimum sample size requirement for the three-level quadratic cross-classified multiple membership growth curve modeling, this study employed a simulation under a variety of conditions including the number of measurement occasions (4, 5, and 6), the number of groups (30, 50, 100, and 200), average group size (10, 30, and 50), and multiple membership rates (20% and 40%). Across all of the simulated conditions, no substantial bias was found for the fixed effect and level-one variance component... -
A Comparison of Three Bayesian Point Estimates for Cross-Classified Multiple Membership Growth Curve Modeling
Chung Hyewon, Jeon Hyeonjeong, Park Soyoung 한국교육학회 교육학연구 26 Pages
한국교육학회 교육학연구 2021, 59권 7호 7 167-192 (26 pages)
mode estimates of the between-school variances in the intercept and slope were substantially overestimated. In general, with the inverse Wishart prior, the Markov chain Monte Carlo (MCMC) posterior median is recommended for cross-classified multiple membership growth curve modeling, except under certain conditions. With the uniform prior, the MCMC mode is recommended for estimating cross-classified multiple membership growth curve modeling rather than the MCMC posterior mean or posterior median. -
Development and Validation of the Theory of Transition to College Student : A Sequential Mixed Method of Grounded Theory and Structural Equation Modeling
Hong Song-Ee 한국교육학회 교육학연구 36 Pages
한국교육학회 교육학연구 2021, 59권 3호 3 55-90 (36 pages)
a questionnaire was developed based on the established transition theory. The validation of the theory was analyzed through structural equation modeling (SEM), and a multi-group analysis was conducted to find out what differences existed in the structural model for dormitory, self-catering, and commuting to school. As a result of the qualitative study, 112 concepts, 34 subcategories, and 9 categories were derived from open coding. As a result of the quantitative analysis through SEM, first, the... -
DESIGN OF ANFIS NETWORKS USING HYBRID GENETIC AND SVD METHODS FOR MODELING AND PREDICTION OF RUBBER ENGINE MOUNT STIFFNESS
Marzbanrad. J., Jamali. A. 한국자동차공학회 International journal of automotive technology 8 Pages
한국자동차공학회 International journal of automotive technology 2009, Vol.10 No.2 167-174 (8 pages)
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Digital Modeling of a Time delayed Continuous-Time System
박종진, 최규석, 박인규, 강정진, Park. Jong-Jin, Choi. Gyoo-Seok, Park. In-Ku, Kang. Jeong-Jin 한국인터넷방송통신학회 한국인터넷방송통신학회 논문지 6 Pages
한국인터넷방송통신학회 한국인터넷방송통신학회 논문지 2012, Vol.12 No.1 211-216 (6 pages)
연속시간 시스템의 제어 이론은 잘 개발되어 왔다. 컴퓨터 기술의 발달로 인해 디지털 제어 기법이 여러 분야에 적용되어 왔다. 제어 시스템에 시간 지연이 있는 경우는 시스템을 효율적으로 제어하는 것이 어렵다. 제어기와 액츄에이터 그리고 센서와 제어기 간에 있는 지연은 제어 성능을 떨어뜨리고 전체 시스템을 불안정하게 할 수 있다. 본 논문에서는 다중의 상태, 입력 그리고 출력 지연을 가지는 제어 시스템을 위한 새로운 근사 이산화 방법과 디지털 설계 그리고 조정가능한 계수를 가지는 일반화된 쌍선형 변환 방법을... -
Practical modeling of cigarette ventilation rate
Kim. Young-Hoh, Lee. Moon-Yong, Rhee. Kyu-Seo, Lee. Dong-Wook 한국연초학회 한국연초학회지 10 Pages
한국연초학회 한국연초학회지 1999, Vol.21 No.2 109-118 (10 pages)
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우리나라 대학생의 혼전 성윤리의식 형성과정 모델화-가톨릭계 대학 여학생을 중심으로
한국종교교육학회 종교교육학연구 2012, 제 40권 8 179-204 (26 pages)
본 연구는 대학생의 혼전 성윤리의식 형성과정에 관한 연구로서 성 가치관 혼란과 성도덕 붕괴의 현실 속에서 대학생들이 어떻게 자신만의 성의식을 형성해 가는지 그 과정과 경험의 의미를 밝히고 이를 모델화하기 위해 Strauss와 Corbin(1998)의 근거이론방법을 적용하여 수행하였다. 연구결과 혼전 성윤리의식 형성과정의 중심현상은 ‘혼란의 늪을 빠져나오기’로 파악되었다. 즉 여학생들의 순결 가치관 형성은 단순한 가정교육의 영향이나 종교적 신념이 아닌 ‘혼란의 늪을 빠져나와 확실한 꿈을 꾸는 과정’이었고, ‘개인과... -
The effects of increased unilateral and bilateral calcaneal eversion on pelvic and trunk alignment in standing position
Jae-hoon Yi 물리치료재활과학회 Physical Therapy Rehabilitation Science 5 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2016, 제 5권 제 2호 5 84-88 (5 pages)
Objective: Generally, it is known that there is a correlation between excessive calcaneus eversion and a patient with low back pain and it also affects pelvic alignment. However, there are not enough studies that show calcaneal eversion having an effect on the alignment of the trunk. Design: Cross-sectional study. Methods: A 3-dimensional motion analysis system was used to assess the lower limbs, pelvic alignment, and trunk alignment with increased unilateral and bilateral calcaneal eversion in... -
Effects of sit-to-stand imagery group training on balance performance in individuals with chronic hemiparetic stroke
Jeong-won Lee, Su-jin Hwang, Sin-ae Ahn 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2016, 제 5권 제 2호 2 63-69 (7 pages)
in Berg balance scale scores in the STS-IGT group (change value, 0.2±4.1 points) compared with the control group (change value, 0.3±0.9 points) (p<0.05). There was a greater improvement in Timed Up and Go scores in the STS-IGT group (change value, 2.6±1.5 sec) compared with the control group (change value, 0.9±1.0 sec) (p<0.05). Conclusions: STS-IGT can be considered as a useful option for restoration of STS movement and balance performance for individuals with chronic hemiparetic stroke who... -
‘가구(家口)’에 대한 고고학적 이해
김범철 한국고고학회 한국고고학전국대회 발표문 19 Pages
한국고고학회 한국고고학전국대회 발표문 제37회 한국고고학대회 1 13-31 (19 pages)
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Kilovoltage radiotherapy for companion animals
Jaehyeon Seo, Jaeman Son, Yeona Cho, Nohwon Park, Dong Wook Kim, Jinsung Kim, Myonggeun Yoon 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 4호 11 550-556 (7 pages)
Radiotherapy for the treatment of cancer in companion animals is currently administered by using megavoltage X-ray machines. Because these machines are expensive, most animal hospitals do not perform radiotherapy. This study evaluated the ability of relatively inexpensive kilovoltage X-ray machines to treat companion animals. A simulation study based on a commercial treatment-planning system was performed for tumors of the brain (non-infectious meningoencephalitis), nasal cavity (malignant nasal... -
Establishment and identification of cell lines from type O blood Korean native pigs and their efficiency in supporting embryonic development via somatic cell nuclear transfer
Anukul Taweechaipaisankul, Geon A Kim, Jun-Xue Jin, Su Cheong Yeom, Byeong Chun Lee 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 4호 3 492-499 (8 pages)
Due to their similarities with humans in anatomy, physiology, and genetics miniature pigs are becoming an attractive model for biomedical research. We aim to establish and evaluate blood type O cells derived from Korean native pig (KNP), a typical miniature pig breed in Korea. Ten cell lines derived from 8 KNP piglets and one adult female KNP (kidney and ear tissues) were established. To confirm the presence of blood type O, genomic DNA, fucosyltransferase (FUT) expression, and... -
Comparison of electrophysiological properties of two types of pre-sympathetic neurons intermingled in the hypothalamic paraventricular nucleus
Yiming Shen, Seong Kyu Han, Pan Dong Ryu 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 4호 2 483-491 (9 pages)
The hypothalamic paraventricular nucleus (PVN) contains two types of neurons projecting to either the rostral ventrolateral medulla (PVNRVLM) or the intermediolateral horn (IML) of the spinal cord (PVNIML). These two neuron groups are intermingled in the same subdivisions of the PVN and differentially regulate sympathetic outflow. However, electrophysiological evidence supporting such functional differences is largely lacking. Herein, we compared the electrophysiological properties of these... -
Cytological endometritis in dairy cows: diagnostic threshold, risk factors, and impact on reproductive performance
Soo Chan Lee, Jae Kwan Jeong, In Soo Choi, Hyun Gu Kang, Young Hun Jung, Soo Bong Park, Ill Hwa Kim 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 2호 17 301-308 (8 pages)
We determined the threshold proportion of polymorphonuclear leukocytes (PMNs) for a diagnosis of cytological endometritis (CEM), the risk factors for this condition, and its impact on reproductive performance in dairy cows. Uterine cytology was performed on 407 Holstein cows 4 weeks postpartum to determine the proportions of endometrial cells and PMNs. A receiver operator characteristics curve was used to determine the threshold above which the PMN proportion affected the likelihood of cows... -
Polymorphism in the serotonin transporter protein gene in Maltese dogs with degenerative mitral valve disease
Chang-Min Lee, Jae-Ik Han, Min-Hee Kang, Seung-Gon Kim, Hee-Myung Park 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 1호 16 129-135 (7 pages)
Degenerative mitral valve disease (DMVD) is the most commonly acquired cardiac disease in dogs. This study evaluated the relationship between genetic variations in the serotonin transporter (SERT) gene of Maltese dogs and DMVD. Genomic DNA was extracted from blood samples collected from 20 client-owned DMVD Maltese dogs and 10 healthy control dogs, and each exon of the SERT gene was amplified via polymerase chain reaction. The resulting genetic sequences were aligned and analyzed for variations... -
Evaluation of a fixed-dose combination of benazepril and pimobendan in dogs with congestive heart failure: a randomized non-inferiority clinical trial
Jonathan N. King, Atsushi Hirakawa, Junko Sonobe, Hiroshi Otaki, Nobuhiro Sakakibara, Wolfgang Seewald, Sophie Forster 대한수의학회 Journal of Veterinary Science 12 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 1호 15 117-128 (12 pages)
A fixed-dose combination tablet of benazepril and pimobendan (Fortekor Plus; Elanco Animal Health) was tested in dogs with congestive heart failure (CHF) caused by myxomatous mitral valve disease (MMVD) in a three-arm, masked, randomized, non-inferiority clinical trial in Japan. The test group (n = 34) received Fortekor Plus twice daily. Two control groups received registered formulations of benazepril (Fortekor; Elanco Animal Health) and pimobendan (Vetmedin; Boehringer Ingelheim Vetmedica)... -
Infections by pathogens with different transmission modes in feral cats from urban and rural areas of Korea
Jusun Hwang, Nicole Gottdenker, Dae-Hyun Oh, Hang Lee, Myung-Sun Chun 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 4호 14 541-545 (5 pages)
In this study, we examine prevalences of three infectious pathogens with different transmission modes (Bartonella henselae, hemoplasma, and Toxoplasma gondii) in feral cats from urban and rural habitats. Infection status of the three pathogens in blood samples (n = 117) was determined through molecular or serological diagnostic methods. Overall prevalence of hemoplasma, Toxoplasma gondii, and Bartonella henselae was 47.9%, 50%, and 35.7%, respectively. Comparing the two habitats, only... -
Pharmacokinetics of tilmicosin in healthy pigs and in pigs experimentally infected with Haemophilus parasuis
Ling Zhang, Li Zhao, Yonghong Liu, Junfeng Liu, Xianqiang Li 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 4호 2 431-437 (7 pages)
A comparative in vivo pharmacokinetic (PK) study of tilmicosin (TIL) was conducted in 6 crossbred healthy pigs and 6 crossbred pigs infected with Haemophilus (H.) parasuis following oral administration of a single 40 mg/kg dose. The infected model was established by intranasal inoculation and confirmed by clinical signs, blood biochemistry, and microscopic examinations. Plasma TIL concentrations were determined by a validated high-performance liquid chromatography method with ultraviolet... -
Tissue distribution of marbofloxacin in pigs after a single intramuscular injection
Fan Yang, Yiming Liu, Zhili Li, Yuqin Wang, Baobao Liu, Zhensheng Zhao, Bianhua Zhou, Guoyong Wang 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 2호 6 169-173 (5 pages)
Tissue distribution of marbofloxacin was studied in pigs after a single intramuscular injection at 2.5 mg/kg body weight. Samples of plasma, muscle, liver, kidney, heart, lung, and muscle at the injection site were randomly collected from five pigs at 2, 6, 10, 24, 48, 72, and 96 h after administration. Marbofloxacin concentrations were determined by using high-performance liquid chromatography with ultraviolet detection and were subjected to non-compartmental analysis to obtain kinetic...
