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Immunostimulatory effects of anionic alkali mineral complex solution Barodon in porcine lymphocytes
Byung Woo Yoo, Soo Il Choi, So Hyun Kim, Soo Jin Yang, Hye Cheong Koo, Sang Hoon Seo, Bong Kyun Park, Han Sang Yoo, Yong Ho Park 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2001, 제 2권 제 1호 3 15-24 (10 pages)
The anionic alkali mineral complex solution, Barodon (Barodon-S.F. Corp., Korea), was evaluated for its effectiveness as a nonspecific immunostimulator in pigs. The effects of Barodon were determined by analysis of feed efficiency, growth rate, and phenotype of leukocyte subpopulations using monoclonal antibodies specific to porcine leukocyte differentiation antigens and flow cytometry (FC). The study was focused to investigate the change in proportion of the CD4+CD8+ double positive T... -
Efficacy evaluation of commercial disinfectants by using Salmonella enterica serovar Typhimurium as a test organism
Yangho Jang, Kwangjick Lee, Seonjong Yun, Myoungheon Lee, Jaeyoung Song, Byungjoon Chang, Nong-hoon Choe 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 2호 11 209-216 (8 pages)
The efficacies of six commercial disinfectants were evaluated by using Salmonella enterica serovar Typhimurium under simulated natural conditions such as sub-zero temperature, short disinfecting time, and surface type (uneven or smooth). We used a suspensionmodel test to determine the disinfecting efficacy under varying contact times (1, 5, 10, and 30 min) and temperatures (25°C, 4°C, 0°C, and -10°C). The bactericidal effect according to surface structure was measured by using a carriermodel... -
Increased humoral antibody response of foot-and-mouth disease virus vaccine in growing pigs pre-treated with poly-γ-glutamic acid
Jee-Hoon Lee, Ik-Jae Kang, A-Reum Kim, You-Sun Noh, Hee-Chun Chung, Bong-Kyun Park 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 2호 15 253-256 (4 pages)
This study was conducted to determine if humoral antibody response of foot-and-mouth disease (FMD) vaccine improved in 8-week-old growing pigs born to well-vaccinated sows pre-treated with 60 mg of poly-γ-glutamic acid (γ-PGA) three days before vaccination. Antibody against FMD virus serotype O was measured 0, 2, 4 and 6 weeks post-vaccination, using a PrioCHECK FMDV type O ELISA kit. The results showed that positive antibody reactions against FMDV serotype O antigen among a component of the... -
Genistein attenuates isoflurane-induced neurotoxicity and improves impaired spatial learning and memory by regulating cAMP/CREB and BDNF-TrkB-PI3K/Akt signaling
TaoJiang, Xiu-qinWang, ChuanDing, Xue-lianDu 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.6 2 579-589 (11 pages)
Anesthetics are used extensively in surgeries and related procedures to prevent pain. However, there is some concern regarding neuronal degeneration and cognitive deficits arising from regular anesthetic exposure. Recent studies have indicated that brain-derived neurotrophic factor (BDNF) and cyclic AMP response element-binding protein (CREB) are involved in learning and memory processes. Genistein, a plant-derived isoflavone, has been shown to exhibit neuroprotective effects. The present study... -
The Critical Roles of Zinc: Beyond Impact on Myocardial Signaling
SungRyulLee, SuJinNoh, JuliusRyanPronto, YuJeongJeong, HyoungKyuKim, InSungSong, ZhelongXu, HyogYoungKwon, SeChanKang, Eun-HwaSohn, KyungS 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.5 1 389-400 (12 pages)
Zinc has been considered as a vital constituent of proteins, including enzymes. Mobile reactive zinc (Zn2+) is the key form of zinc involved in signal transductions, which are mainly driven by its binding to proteins or the release of zinc from proteins, possibly via a redox switch. There has been growing evidence of zinc’s critical role in cell signaling, due to its flexible coordination geometry and rapid shifts in protein conformation to perform biological reactions. The importance and... -
Comparison of Ectopic Gene Expression Methods in Rat Neural Stem Cells
WoosukKim, JiHyeonKim, Sun-YoungKong, Min-HyePark, UyDongSohn, Hyun-JungKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.1 4 23-30 (8 pages)
Neural stem cells (NSCs) have the ability to proliferate and differentiate into various types of cells that compose the nervous system. To study functions of genes in stem cell biology, genes or siRNAs need to be transfected. However, it is difficult to transfect ectopic genes into NSCs. Thus to identify the suitable method to achieve high transfection efficiency, we compared lipid transfection, electroporation, nucleofection and retroviral transduction. Among the methods that we tested, we... -
Quercetin-induced Growth Inhibition in Human Bladder Cancer Cells Is Associated with an Increase in Ca2+-activated K+ Channels
YangmiKim, Wun-JaeKim, , Eun-JongCha 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.5 5 279-284 (6 pages)
Quercetin (3,3',4',5,7-pentahydroxyflavone) is an attractive therapeutic flavonoid for cancer treatment because of its beneficial properties including apoptotic, antioxidant, and antiproliferative effects on cancer cells. However, the exact mechanism of action of quercetin on ion channel modulation is poorly understood in bladder cancer 253J cells. In this study, we demonstrated that large conductance Ca2+- activated K+ (BKCa) or MaxiK channels were functionally expressed in 253J cells, and... -
Effects of Chlorhexidine digluconate on Rotational Rate of n-(9-Anthroyloxy)stearic acid in Model Membranes of Total Lipids Extracted from Porphyromonas gingivalis Outer Membranes
Hye-OckJang, Dong-WonKim, Byeong-IllKim, Hong-GuSim, Young-HoLee, Jong-HwaLee, Jung-HaBae, Moon-KyoungBae, Tae-HyukKwon, IlYun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.2 3 83-88 (6 pages)
The purpose of this study was to provide a basis for studying the molecular mechanism of pharmacological action of chlorhexidine digluconate. Large unilamellar vesicles (OPGTL) were prepared with total lipids extracted from cultured Porphyromonas gingivalis outer membranes (OPG). The anthroyloxy probes were located at a graded series of depths inside a membrane, depending on its substitution position (n) in the aliphatic chain. Fluorescence polarization of n-(9-anthroyloxy)stearic acid was used... -
Effects of Chlorhexidine Digluconate on Rotational Rate of n-(9-Anthroyloxy)stearic Acid in Porphyromonas ginginvalis Outer Membranes
Hye-OckJang, Seong-KweonCha, ChangLee, Min-GakChoi, Sung-RyulHuh, Sang-HunShin, In-KyoChung, IlYun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.3 2 125-130 (6 pages)
The aim of this study was to provide a basis for studying the molecular mechanism of pharmacological action of chlorhexidine digluconate. Fluorescence polarization of n-(9-anthroyloxy)stearic acid was used to examine the effect of chlorhexidine digluconate on differential rotational mobility of different positions of the number of membrane bilayer phospholipid carbon atoms. The six membrane components differed with respect to 2, 3, 6, 9, 12, and 16-(9-anthroyloxy)stearic acid (2-AS, 3-AS, 6-AS,... -
Molecular Aspects of Organic Ion Transporters in the Kidney
SeokHoChaHitoshiEndou 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 16 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.2 1 107-122 (16 pages)
A function of the kidney is elimination of a variety of xenobiotics ingested and wasted endogenous compounds from the body. Organic anion and cation transport systems play important roles to protect the body from harmful substances. The renal proximal tubule is the primary site of carrier-mediated transport from blood into urine. During the last decade, molecular cloning has identified several families of multispecific organic anion and cation transporters, such as organic anion transporter... -
HOCl과 NH2Cl에 의한 Hyaluronic Acid의 변성에 있어서 Taurine의 억제 효과
이정수(Chung-Soo Lee), 이경용(Kyung-Yong Lee), 이광수(Kwang-Soo Lee) 대한약리학회 대한약리학잡지 12 Pages
대한약리학회 대한약리학잡지 1992, 제 28권 제 2호 9 201-212 (12 pages)
외인성 taurine이 HOCl, NH2Cl과 그밖의 산화성 물질에 의한 hyaluronic acid의 변성에 미치는 영향을 관찰하였다. HOCl, NH2Cl과 그밖의 산화성 물질에 대한 taurine의 제거 작용을 조사하였다. Taurine의 항 산화 작용을 또한 치올 화합물의 작용과 비교 관찰하였다. Hyaluronic acid의 점성도는 HOCl과 NH2Cl에 의하여 뚜렷하게 용량에 따라 감소하였다. Hyaluronic acid에 대한 HOCl의 변성 효과는 NH2Cl에 의한 것보다 현저하였다. Taurine은 HOCl과 NH2Cl에 의한 hyaluronic acid의 변성을 효과적으로 용량에 따라 억제하였다.... -
Benzyl Alcohol이 세포막의 형태 및 Calcium 이온 이동에 미치는 영향
이황현(Lee, Hwang-Hyun), 하종식(Hah, Jong-Sik), 김구자(Kim, Ku-Ja) 대한생리학회 대한생리학회지 12 Pages
대한생리학회 대한생리학회지 1987, 제 21권 제 2호 1 157-168 (12 pages)
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Selection of Small Synthetic Antimicrobial Peptides Inhibiting Xanthomonas citri subsp. citri Causing Citrus Canker
한국식물병리학회 The Plant Pathology Journal 8 Pages
한국식물병리학회 The Plant Pathology Journal 2017, 33권 1호 10 87-94 (8 pages)
Citrus canker disease decreases the fruit quality and yield significantly, furthermore, emerging of streptomycin-resistant pathogens threatens the citrus industry seriously because of a lack of proper control agents. Small synthetic antimicrobial peptides (AMPs) could be a promising alternative. Fourteen hexapeptides were selected by using positional scanning of synthetic peptide combinatorial libraries. Each hexapeptide showed different antimicrobial spectrum against Bacillus, Pseudomonas,... -
Antimicrobial Cyclic Peptides for Plant Disease Control
한국식물병리학회 The Plant Pathology Journal 11 Pages
한국식물병리학회 The Plant Pathology Journal 2015, 31권 1호 1 1-11 (11 pages)
Antimicrobial cyclic peptides derived from microbes bind stably with target sites, have a tolerance to hydrolysis by proteases, and a favorable degradability under field conditions, which make them an attractive proposition for use as agricultural fungicides. Antimicrobial cyclic peptides are classified according to the types of bonds within the ring structure; homodetic, heterodetic, and complex cyclic peptides, which in turn reflect diverse physicochemical features. Most antimicrobial cyclic... -
Antimicrobial Effects of a Hexapetide KCM21 against Pseudomonas syringae pv. tomato DC3000 and Clavibacter michiganensis subsp. michiganensis
한국식물병리학회 The Plant Pathology Journal 9 Pages
한국식물병리학회 The Plant Pathology Journal 2014, 30권 3호 2 245-253 (9 pages)
Antimicrobial peptides (AMPs) are small but effective cationic peptides with variable length. In previous study, four hexapeptides were identified that showed antimicrobial activities against various phytopathogenic bacteria. KCM21, the most effective antimicrobial peptide, was selected for further analysis to understand its modes of action by monitoring inhibitory effects of various cations, time-dependent antimicrobial kinetics, and observing cell disruption by electron microscopy. The effects... -
Three-dimensional porous graphene materials for environmental applications
Muruganantham Rethinasabapathy, Sung-Min Kang, Sung-Chan Jang, Yun Suk Huh 한국탄소학회 Carbon Letters 13 Pages
한국탄소학회 Carbon Letters 2017, Vol.22 1 1-13 (13 pages)
Porous materials play a vital role in science and technology. The ability to control their pore structures at the atomic, molecular, and nanometer scales enable interactions with atoms, ions and molecules to occur throughout the bulk of the material, for practical applications. Three-dimensional (3D) porous carbon-based materials (e.g., graphene aerogels/hydrogels, sponges and foams) made of graphene or graphene oxide-based networks have attracted considerable attention because they offer low... -
NO gas sensing ability of activated carbon fibers modified by an electron beam for improvement in the surface functional group
Mi-Seon Park, Sangmin Lee, Min-Jung Jung, Hyeong Gi Kim, Young-Seak Lee 한국탄소학회 Carbon Letters 7 Pages
한국탄소학회 Carbon Letters 2016, Vol.20 3 19-25 (7 pages)
Activated carbon fiber (ACF) surfaces are modified using an electron beam under different aqueous solutions to improve the NO gas sensitivity of a gas sensor based on ACFs. The oxygen functional group on the ACF surface is changed, resulting in an increase of the number of non-carbonyl (-C-O-C-) groups from 32.5% for pristine ACFs to 39.53% and 41.75% for ACFs treated with hydrogen peroxide and potassium hydroxide solutions, respectively. We discover that the NO gas sensitivity of the gas sensor... -
Catalytic activity and controllable deposition of platinum nanoparticles on ionic polymer-functionalized graphene as catalysts for direct methanol fuel cells
Jiyoung Park, Changyoon Song, Qizhong Sun, Yongju Jung, Seok Kim 한국탄소학회 Carbon Letters 5 Pages
한국탄소학회 Carbon Letters 2015, Vol.16 No.4 6 260-264 (5 pages)
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Preparation and characterization of microporous NaOH activated carbons from hydrofluoric acid leached rice husk and its application for lead(II) adsorption
A. F. Hassan, A. M. Youssef 한국탄소학회 Carbon Letters 10 Pages
한국탄소학회 Carbon Letters 2014, Vol.15 No.1 8 57-66 (10 pages)
as an activating agent. Hydrofluoric acid pre-leached rice husk was used as a precursor. After leaching, the precursor was washed with distilled water, dried, crushed, and then sieved; a size fraction of 0.3-0.5 mm was selected for carbonization in the absence of air at 600°C. The carbonization product (LC) was mixed with NaOH at ratios of 1:2, 1:3, and 1:4 (wt of LC: wt of NaOH) and the produced ACs after activation at 800°C were designated NLC21, NLC31, and NLC41, respectively. Surface and... -
Removal of deltamethrin insecticide over highly porous
A. F. Hassan, A.M. Youssef, P. Priecel 한국탄소학회 Carbon Letters 9 Pages
한국탄소학회 Carbon Letters 2013, Vol.14 No.4 6 234-242 (9 pages)
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모래여과를 이용한 도시하천유지용수의 MBAS 제거 효율 평가
김홍배, 안경수 한국습지학회 한국습지학회지 7 Pages
한국습지학회 한국습지학회지 2006, Vol.8 No.2 1 45-51 (7 pages)
우리나라 대부분의 하수처리장에서는 영양염류 및 MBAS의 제거를 위하여 생물학적 고도처리시설 과 모래여과시설을 설치하여 운영하고 있다. 그러나 미처리된 영양염류 및 합성세제가 수계에 그대로 유입되어 하천에 사상성부착조류의 발생 및 하천의 자정작용을 방해하여 물에서의 이․취미 발생과 거품 때문에 미관상 불쾌하여 하수처리수를 도시하천유지용수로 재이용하는 G 하수처리장을 실험 대상으로 하여 모래여과시설에 대한 MBAS 제거효율을 파악하고자 본 연구를 실시하였다. 그 결과 모래여과를 이용한 MBAS의 최대 제거... -
리빙 음이온 중합법에 의한 SIS Triblock 공중합체의 제조 및 유류 고형화 특성
허재준, 이민규, 김시영, 주창식, Heo. Jae-Joon, Lee. Min-Gyu, Kim. Si-Young, Ju. Chang-Sik 한국환경과학회 한국환경과학회지 8 Pages
한국환경과학회 한국환경과학회지 2006, Vol.15 No.6 593-600 (8 pages)
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반응형 음이온화제 처리 면직물에 대한 중금속 이온의 흡착특성
김미경, 윤석한, 김태경, 임용진, Kim. Mi-Kyung, Yoon. Seok-Han, Kim. Tae-Kyeong, Lim. Yong-Jin 한국염색가공학회 韓國染色加工學會誌 10 Pages
한국염색가공학회 韓國染色加工學會誌 2005, Vol.17 No.1 20-29 (10 pages)
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반응형 음이온화제의 정전기적 인력에 의한 베르베린 색소의 염착성 향상
김태경, 윤석한, 임용진, 손영아 한국염색가공학회 韓國染色加工學會誌 8 Pages
한국염색가공학회 韓國染色加工學會誌 2003, Vol.15 No.6 47-54 (8 pages)
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셀룰로오스 섬유용 반응형 디클로로트리아진계 음이온화제의 합성 및 응용
김태경, 윤석한, 임용진, 손영아 한국염색가공학회 韓國染色加工學會誌 7 Pages
한국염색가공학회 韓國染色加工學會誌 2003, Vol.15 No.5 294-300 (7 pages)
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Heparin Attenuates the Expression of TNFα-induced Cerebral Endothelial Cell Adhesion Molecule
JeongHoLee, ChulHoonKim, GiHoSeo, JinuLee, JooHeeKim, DongGooKim, YoungSooAhn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.5 3 231-236 (6 pages)
Heparin is a well-known anticoagulant widely used in various clinical settings. Interestingly, recent studies have indicated that heparin also has anti-inflammatory effects on neuroinflammation-related diseases, such as Alzheimer's disease and meningitis. However, the underlying mechanism of its actions remains unclear. In the present study, we examined the anti-inflammatory mechanism of heparin in cultured cerebral endothelial cells (CECs), and found that heparin inhibited the tumor necrosis... -
A review: synthesis and applications of graphene/chitosan nanocomposites
Hui Yuan, Long-Yue Meng, Soo-Jin Park 한국탄소학회 Carbon Letters 7 Pages
한국탄소학회 Carbon Letters 2016, Vol.17 No.1 2 11-17 (7 pages)
Recently, with continuous developments in the field of materials science, graphene oxide (GO) has emerged as a promising material with excellent electrical, thermal, mechanical, and optical properties, which play important roles in most fields. Researchers have achieved considerable progress with graphene. Chitosan (CS) is a natural polymer that has been studied intensively owing to its specific formation, high chemical resistance, and excellent physical properties. These outstanding properties...


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