자료유형
전체 선택해제
총 19건 검색
본문검색 결과만 보기
-
Cytotoxicity and Structure-activity Relationships of Naphthyridine Derivatives in Human Cervical Cancer, Leukemia, and Prostate Cancer
YuJinHwang, MiLyangChung, UyDongSohn, ChaeukIm 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.6 7 517-524 (8 pages)
Naphthyridine compounds are important, because they exhibit various biological activities including anticancer, antimicrobial, and anti-inflammatory activity. Some naphthyridines have antimitotic effects or demonstrate anticancer activity by inhibiting topoisomerase II. These compounds have been investigated as potential anticancer agents, and several compounds are now part of clinical trials. A series of naphthyridine derivatives were evaluated for their in vitro cytotoxic activities against... -
Cytotoxicities and Quantitative Structure Activity Relationships of B13 Sulfonamides in HT-29 and A549 Cells
SeulKiChanLee, SangMinPark, ChaeukIm 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.6 14 423-430 (8 pages)
B13 analogues are being considered as therapeutic agents for cancer cells, since B13 is a ceramide analogue and inhibits ceramidase to promote apoptosis in cancer cells. B13 sulfonamides are assumed to have biological activity similar to B13, since they are made by bioisosterically substituting the carboxyl moiety of B13 with sulfone group. Twenty B13 sulfonamides were evaluated for their in vitro cytotoxicities against human colon cancer HT-29 and lung cancer A549 cell lines using MTT assays.... -
Cytotoxic Activity and Structure Activity Relationship of Ceramide Analogues in Caki-2 and HL-60 Cells
YongJinKim, EunAeKim, UyDongSohn, ChulBuYim, ChaeukIm 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.6 14 441-447 (7 pages)
B13, a ceramide analogue, is a ceramidase inhibitor and induces apoptosis to give potent anticancer activity. A series of thiourea B13 analogues was evaluated for their in vitro cytotoxic activities against human renal cancer Caki-2 and leukemic cancer HL-60 in the MTT assay. Some compounds (12, 15, and 16) showed stronger cytotoxicity than B13 and C6-ceramide against both tumor cell lines, and compound (12) gave the most potent activity with IC50 values of 36 and 9</SUB>ՌM,... -
Hydrogen Peroxide Prompted Lignification Affects Pathogenicity of Hemi-biotrophic Pathogen Bipolaris sorokiniana to Wheat
Ajit Poudel, Sudhir Navathz, Ramesh Chand, Vinod K. Mishra, Pawan K. Singh, Arun K. Joshi 한국식물병리학회 The Plant Pathology Journal 14 Pages
한국식물병리학회 The Plant Pathology Journal 2019, 35권 4호 1 287-300 (14 pages)
Spot blotch caused by Bipolaris sorokiniana has spread to more than 9 million ha of wheat in the warm, humid areas of the Eastern Gangetic Plains (EGP) of South Asia and is a disease of major concern in other similar wheat growing regions worldwide. Differential lignin content in resistant and susceptible genotypes and its association with free radicals such as hydrogen peroxide (H2O2), superoxide (O2 -) and hydroxyl radical (OH-) were studied after inoculation under field conditions for two... -
Dispersions of partially reduced graphene oxide in various organic solvents and polymers
Hye Min Kim, Seo Gyun Kim, Heon Sang Lee 한국탄소학회 Carbon Letters 8 Pages
한국탄소학회 Carbon Letters 2017, Vol.23 8 55-62 (8 pages)
We report on the dispersion state of partially reduced graphene oxide (PRGO) in organic solvents, namely methyl ethyl ketone, ethyl acetate, methylene chloride, toluene, and xylene, by controlling the carbon to oxygen (C/O) atomic ratio of the PRGOs. A two-phase solvent exchange method is also proposed to transfer PRGO from water to an aprotic solvent, such as methyl ethyl ketone. We achieve relatively good dispersion in aprotic and non-polar solvents by controlling the C/O atomic ratio of the... -
Synthesize multi-walled carbon nanotubes via catalytic chemical vapour deposition method on Fe-Ni bimetallic catalyst supported on kaolin
Aliyu A, Abdulkareem AS, Kovo AS, Abubakre OK, Tijani JO, Kariim I 한국탄소학회 Carbon Letters 18 Pages
한국탄소학회 Carbon Letters 2017, Vol.21 5 33-50 (18 pages)
In this study, Fe-Ni bimetallic catalyst supported on kaolin is prepared by a wet impregnation method. The effects of mass of kaolin support, pre-calcination time, pre-calcination temperature and stirring speed on catalyst yields are examined. Then, the optimal supported Fe-Ni catalyst is utilised to produce multi-walled carbon nanotubes (MWCNTs) using catalytic chemical vapour deposition (CCVD) method. The catalysts and MWCNTs prepared using the optimal conditions are characterized using high... -
Electrochemical synthesis of nanosized hydroxyapatite/graphene composite powder
Vesna Mi?kovi?-Stankovi?, Sanja Erakovi?, Ana Jankovi?, Maja Vuka?inovi?-Sekuli?, Miodrag Mitri?, Young Chan Jung, Soo Jin Park, Kyong 한국탄소학회 Carbon Letters 8 Pages
한국탄소학회 Carbon Letters 2015, Vol.16 No.4 2 233-240 (8 pages)
Electrochemical synthesis was employed to prepare a novel hydroxyapatite/graphene (HAP/ Gr) composite powder suitable for medical applications as a hard tissue implant (scaffold). The synthesis was performed in a homogeneous dispersion containing Na2H2EDTA·2H2O, NaH2PO4 and CaCl2 with a Ca/EDTA/PO4 3? concentration ratio of 0.25/0.25/0.15M, along with 0.01 wt% added graphene nanosheets, at a current density of 137 mA cm?2 and pH value of 9.0. The field emission scanning electron microscopy and... -
Non-blinking dendritic crystals from C-dot solution
Ashmi Mewada, Ritesh Vishwakarma, Bhushan Patil, Chinmay Phadke 한국탄소학회 Carbon Letters 4 Pages
한국탄소학회 Carbon Letters 2015, Vol.16 No.3 8 211-214 (4 pages)
Bio-imaging and drug carriers for delivery have created a huge demand for crystals. Crystals are fascinating materials that have been grown for a long time but obtaining biocompatible fluorescent crystals is a challenging task. We report on the growth of fluorescent crystals using a carbon dot (C-dot) solution by a hydrothermal process. The crystallization pattern of these C-dots exhibited a unique dendritic structure having a feather-like morphology. The growth temperature and pressure were... -
Double-walled carbon nanotubes: synthesis, structural characterization, and application
Yoong Ahm Kim, Kap-Seung Yang, Hiroyuki Muramatsu, Takuya Hayashi, Morinobu Endo, Mauricio Terrones, Mildred S. Dresselhaus 한국탄소학회 Carbon Letters 12 Pages
한국탄소학회 Carbon Letters 2014, Vol.15 No.2 4 77-88 (12 pages)
Double walled carbon nanotubes (DWCNTs) are considered an ideal model for studying the coupling interactions between different concentric shells in multi-walled CNTs. Due to their intrinsic coaxial structures they are mechanically, thermally, and structurally more stable than single walled CNTs. Geometrically, owing to the buffer-like function of the outer tubes in DWCNTs, the inner tubes exhibit exciting transport and optical properties that lend them promise in the fabrication of field-effect... -
Water and oxygen permeation through transparent ethylene vinyl alcohol/(graphene oxide) membranes
Hye Min Kim, Heon Sang Lee 한국탄소학회 Carbon Letters 7 Pages
한국탄소학회 Carbon Letters 2014, Vol.15 No.1 7 50-56 (7 pages)
We prepared ethylene vinyl alcohol (EVOH)/graphene oxide (GO) membranes by solution casting method. X-ray diffraction analysis showed that GOs were fully exfoliated in the EVOH/GO membrane. The glass transition temperatures of EVOH were increased by adding GOs into EVOH. The melting temperatures of EVOH/GO composites were decreased by adding GOs into EVOH, indicating that GOs may inhibit the crystallization of EVOH during non-isothermal crystallization. However, the equilibrium melting... -
대표농도경로 시나리오에 의한 미래 강수량의 지역빈도해석
김덕환, 홍승진, 최창현, 한대건, 이종소, 김형수 한국습지학회 한국습지학회지 11 Pages
한국습지학회 한국습지학회지 2015, Vol.17 No.1 10 80-90 (11 pages)
기후변화로 인해 강우 패턴과 강우강도의 변동성이 커지고 있으며, 도시화 및 산업화에 따른 불투수면적의 증가로 인 해, 집중호우에 따른 도시침수와 홍수피해가 심화될 것으로 예상하고 있다. 따라서 본 연구에서는 홍수방어 대안 설정 을 위한 설계 강수량(design rainfall) 또는 확률강수량에도 변화가 예상되므로 지역빈도해석을 통해 미래 확률강수량 을 산정 및 분석하고자 한다. 기상청 산하 30년 이상의 관측치를 갖고 있는 58개 지점을 대상으로 과거 관측자료를 수집하고, 기후변화를 고려한 미래 확률강수량 추정을 위해... -
RCP 시나리오를 고려한 극치통계분석 및 빈도해석
김덕환, 김연수, 홍승진, Ly Sidoeun, 정영훈, 김형수 한국습지학회 한국습지학회지 13 Pages
한국습지학회 한국습지학회지 2013, Vol.15 No.4 19 595-607 (13 pages)
본 연구에서는 기상청 산하 30년 이상의 관측치를 갖고 있는 기상관측소 58개 지점을 대상으로, 과거 관측자료 및 대표 농도경로(RCP) 시나리오에 의한 강수량 자료를 이용하여 극치통계분석 및 확률강수량을 산정하였다. 기후변화 시나리오 자료의 편의를 제거하기 위하여 분위사상법(Quantile Mapping) 및 이상치 검정을 실시하였다. 이를 통해 보정된 시나리오 값을 이용하여 ETCCDI 극한지수 중에서 강수관련 지수를 이용한 극치통계분석을 실시하였고, 빈도해석을 통한 미래 목 표기간별 확률강수량의 변화율을 살펴보았다. 미래... -
유한차분법과 유한체적법을 이용한 1차원과 2차원 개수로 흐름해석
김만식, 이진희, 정찬, 박노혁 한국습지학회 한국습지학회지 13 Pages
한국습지학회 한국습지학회지 2008, Vol.10 No.2 5 67-79 (13 pages)
하천에서의 부정류 해석을 위해서 1차원 유한차분법(FDM)인 Abbott-Ionescu scheme과 2차원 유한체적법(FVM)인 근사의 Riemann solver(Osher scheme)에 대하여 살펴보았다. 두 모형은 직선 하도, 약간 굽어진 사행하도 및 사행하도에서의 흐름 문제들에 적용되었으며 결과의 비교는 균일한 직사각형 수로에 대하여 이루어졌다. 하천의 복잡한 형상의 표현하기 위해서는 이를 고려할 수 있는 유한체적법을 이용하였다. 유한차분법과 유한체적법 결과는 수위 및 유량 수문곡선에 대하여 매우 만족스러운 것으로 나타났다. 균일한 직선하도에... -
선형 격자 형성 방정식을 이용한 직교 격자 형성에 관한 연구
이상욱, 권장혁, 권오준, Lee. S. W., Kwon. J. H., Kwon. O. J. 한국전산유체공학회 한국전산유체공학회지 8 Pages
한국전산유체공학회 한국전산유체공학회지 2000, Vol.5 No.1 14-21 (8 pages)
-
Towards Prediction of Unsteady Turbulent Flow over a Square Cylinder using Two-Equation Turbulence Models
이상산, Lee. Sangsan 한국전산유체공학회 한국전산유체공학회지 8 Pages
한국전산유체공학회 한국전산유체공학회지 1996, Vol.1 No.1 47-54 (8 pages)
비유선형 물체 주위의 유동은 정체유동, 경계층 박리 및 재부착, 주기적 와열의 생성등의 복잡한 유동현상이 공존한다. 이와 같은 유동의 2-방정식 난류모델을 이용한 정확한 예측은 일반적으로 불가능 하다고 인식되어 왔으나, 본 연구에서는 기존의 비교적 단순한 난류모델을 활용한 정사각주 주위의 비정상 난류유동의 예측 가능성을 체계적으로 규명하였다. 적절한 난류모델의 선정과 더불어 시간 정확도, 공간 정확도 및 대류항 처리법 등이 해석의 결과에 미치는 영향을 살펴 보았다. 기존의 표준 κ-ε모델은 정체점 주위에서...
