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전체 선택해제
총 97건 검색
본문검색 결과만 보기
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NSC(국가안전보장회의) 체제의 한미일 비교
한국경호경비학회 시큐리티연구 2013, 제 37호 2 29-50 (22 pages)
아베 신조(安部普三) 내각 등 새로운 정권 출범을 맞아, 공히 주요 선거공약으로 제시한바 있는 위기관리 및 안보 정책의 정비 ? 강화를 시도하고 있다. 그 핵심 중 하나는 최근 미국의 모델을 참조로 한 안보 및 위기관리 정책에서의 NSC 또는 그 유사 기구의 기능 확대 및 강화이다. 해당 각국의 NSC 조직은 각기 다른 특성을 가지고 있으나, 현 정치 ? 안보 상황에서 안보 및 위기관리 정책의 컨트롤 타워로서 주된 역할을 담당할 수 있는 잠재성이 있다고 볼 수 있다. 따라서 이 논문에서는 한국, 미국, 일본 등 3개 국가 정부의 NSC... -
지속가능경영 외국사례 - NSC 일본, 철강
한국환경기술인연합회 한국환경기술인연합회 환경기술인 3 Pages
한국환경기술인연합회 환경기술인 2004, Vol.21 No.2 30-32 (3 pages)
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NSC를 첨가한 소일시멘트의 일축압축강도
김병일, 김영욱, 이승현 한국지반공학회 韓國地盤工學會論文集 7 Pages
한국지반공학회 韓國地盤工學會論文集 2002, Vol.18 No.4 159-165 (7 pages)
소일시멘트는 보수, 보강이 쉬우며, 경제적이고, 자연 친화적이기 때문에 도로포장, 사면보호, 흙막이 벽체, 연약지반 개량 등 여러 분야에 활용되고 있으며, 최근에는 소일시멘트의 강도를 증가시키기 위해 특수 혼화재료를 섞어서 사용하는 경우가 많아졌다. 이 연구에서는 혼화재료인 NSC(New Soil Chemical)를 섞은 소일시멘트의 일축압축강도를 측정하는 실험을 수행하였으며, 흙 종류, 시멘트 함량, NSC 혼합비에 따른 일축압축강도의 변화 양상을 파악하고자 하였다. 연구결과 NSC 용액은 흙종류에 따라 차이는 있으나 일축압축강도를... -
발행인 만남 - 이종석 세종연구소 수석연구위원/전 통일부장관 겸 NSC 상임위원장
유동준, Yu. Dong-Jun 한국단미사료협회 피드저널 4 Pages
한국단미사료협회 피드저널 2007, Vol.5 No.10 65-68 (4 pages)
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RELAP5/MOD1/NSC를 이용한 원자력 1호기 외부전원상실사고해석;II:설계기준사고
Kim. Hyo-Jung, Chung. Bub-Dong, Lee. Young-Jin, Kim. Jin-Soo 한국원자력학회 Journal of the Korean Nuclear Society 8 Pages
한국원자력학회 Journal of the Korean Nuclear Society 1986, Vol.18 No.3 175-182 (8 pages)
열, 수력학적 최적 계산용 코드인 RELAP5/MOD1/NSC를 사용하여 모의하였다. 본 분석은 최적 계산모델로 수행되었으나, 사고 전개 및 가정등 보수성을 갖는 평가 방법에 의거하였다. 해석결과중 노심평균온도, 증기발생기 및 가압기 수위 등의 중요한 열·수력학적 변수를 원자력 1호기의 최종 안전성 분석보고서의 결과와 비교하였다. 본 해석결과에서 노심평균온도와 가압기 수위는 보다 낮게, 증기발생기 수위는 보다 높게 나타남으로써 더 향상된 안전한계치를 확인하였다. 이것은 본 해석에서 최적 열·수력 모델을 사용하였을 뿐만... -
RELA5/MOD1/NSC를 이용한 원자력 1호기 외부전원상실사고해석 - I. 실제사고해석
Kim. Hho-Jung, Chung. Bub-Dong, Lee. Young-Jin, Kim. Jin-Soo 한국원자력학회 Journal of the Korean Nuclear Society 10 Pages
한국원자력학회 Journal of the Korean Nuclear Society 1986, Vol.18 No.2 97-106 (10 pages)
열, 수력학적최적계산용 코드인 RELAP5/MODl/NSC를 사용하여 모의하였으며 해석결과는 발전소 실측자료와 잘 일치하였다. 원자로 냉각재펌프의 트립에 따른 flow coastdown후에 hot-cold leg온도차에 의하여 자연순환 유동이 형성됨이 확인되었으며 실측자료와 잘 일치하여 이와 관련된 전산코드의 열수력학 적모델의 타당성을 입증할 수 있었다. 또한 위의 사고전개가 정상운전상태인 전출력(100%)에서 재발하였을 경우를 가정하여 해석하였다. 이러한 해석을 통하여 보조급수의 공급과 더불어 증기발생기 PORV의 적절한 작동으로 원자력... -
아시아 지역 영연방국가의 지정하도급(NSC)제도에 관한 비교 연구 - 표준계약약관의 지정하도급자 항목분석을 중심으로 -
조재용, 김정곤, 박형근, Cho. Jaeyong, Kim. Junggon, Park. Hyeonggeun 한국건설관리학회 한국건설관리학회논문집 11 Pages
한국건설관리학회 한국건설관리학회논문집 2014, Vol.15 No.3 12-22 (11 pages)
프로젝트 주체가 참여하고 있으며, 프로젝트를 둘러싼 수행환경 및 계약관행이 국내 건설 프로젝트와 다르기 때문에 다양한 리스크 요인이 존재하고 있다. 특히 해외건설 프로젝트의 문제가운데 하나가 Nominated Sub-Contracting (NSC)로 알려진 영국과 영국연방국가에서 사용되어지고 있는 하도급계약이다. 본 논문은 영국과 아시아지역 영연방 국가의 JCT약관, SIA약관, HKIA약관, PAM약관의 비교를 통해 NSC제도와 차이점을 소개한다. 또한 NSC계약의 채용 거부와 계약 해지와 관련된 약관항목분석을 통해 NSC제도의 유형을 분류한다. -
미국의 국가안전보장정책 결정과정(6)-NSC의 역할(하)
김현보, Kim. Hyeon-Bo 한국방위산업진흥회 國防과 技術 10 Pages
한국방위산업진흥회 國防과 技術 1988, Vol.1988 No.7 38-47 (10 pages)
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미국의 국가안전보장정책 결정과정(5)-NSC의 역할(중)
김현보, Kim. Hyeon-Bo 한국방위산업진흥회 國防과 技術 9 Pages
한국방위산업진흥회 國防과 技術 1988, Vol.1988 No.6 12-20 (9 pages)
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Direct lineage transition by defined factors
Kyung Tae Lim, Sung Min Kim, Seung Chan Lee, Jong Hun Kim, Tae Hwan Kwak, Dong Wook Han, 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 춘계학술심포지움 10 79-79 (1 pages)
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Effects of neural stem cells and 5-fluorocytosine in canine metastatic lung tumor
Yawon Hwang, Dongwook Kim, Dongwoo Chang, Byeongwoo Ahn, Yun-Bae Kim, Gonhyung Kim 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 2호 17 257-260 (4 pages)
cell (NSC)/5-fluorocytosine (5-FC) therapy on canine metastatic lung tumor. The therapeutic effects appeared approximately two weeks after 5-FC administration. Thoracic radiographs revealed a reduced number of lung nodules and decreased nodule size. However, there were no significant antitumor effects on primary lesions in abdominal organs. In conclusion, human NSC/5-FC prodrug therapy can secure patient quality of life with the same or more therapeutic effects and fewer side effects than other... -
Metabolism and excretion of novel pulmonary-targeting docetaxel liposome in rabbits
JieWang, LiZhang, LijuanWang, ZhonghongLiu, YuYu 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.1 6 45-54 (10 pages)
Our study aims to determine the metabolism and excretion of novel pulmonary-targeting docetaxel liposome (DTX-LP) using the in vitro and in vivo animal experimental models. The metabolism and excretion of DTX-LP and intravenous DTX (DTX-IN) in New Zealand rabbits were determined with ultra-performance liquid chromatography tandem mass spectrometry. We found DTX-LP and DTX-IN were similarly degraded in vitro by liver homogenates and microsomes, but not metabolized by lung homogenates.... -
Epigallocatechin-3-gallate rescues LPS-impaired adult hippocampal neurogenesis through suppressing the TLR4-NF-κB signaling pathway in mice
Kyung-JooSeong, Hyun-GwanLee, MinSukKook, Hyun-MiKo, Ji-YeonJung, Won-JaeKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.1 6 41-51 (11 pages)
Adult hippocampal dentate granule neurons are generated from neural stem cells (NSCs) in the mammalian brain, and the fate specification of adult NSCs is precisely controlled by the local niches and environment, such as the subventricular zone (SVZ), dentate gyrus (DG), and Toll-like receptors (TLRs). Epigallocatechin-3-gallate (EGCG) is the main polyphenolic flavonoid in green tea that has neuroprotective activities, but there is no clear understanding of the role of EGCG in adult neurogenesis... -
Disappearance of Hypoxic Pulmonary Vasoconstriction and O2-Sen-sitive Nonselective Cationic Current in Arterial Myocytes of Rats Under Ambient Hypoxia
HaeYoungYoo, SungJoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.5 13 463-468 (6 pages)
Acute hypoxia induces contraction of pulmonary artery (PA) to protect ventilation/perfusion mismatch in lungs. As for the cellular mechanism of hypoxic pulmonary vasoconstriction (HPV), hypoxic inhibition of voltage-gated K+ channel (Kv) in PA smooth muscle cell (PASMC) has been suggested. In addition, our recent study showed that thromboxane A2 (TXA2) and hypoxia-activated nonselective cation channel (INSC) is also essential for HPV. However, it is not well understood whether HPV is maintained... -
Comparison of Ectopic Gene Expression Methods in Rat Neural Stem Cells
WoosukKim, JiHyeonKim, Sun-YoungKong, Min-HyePark, UyDongSohn, Hyun-JungKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.1 4 23-30 (8 pages)
Neural stem cells (NSCs) have the ability to proliferate and differentiate into various types of cells that compose the nervous system. To study functions of genes in stem cell biology, genes or siRNAs need to be transfected. However, it is difficult to transfect ectopic genes into NSCs. Thus to identify the suitable method to achieve high transfection efficiency, we compared lipid transfection, electroporation, nucleofection and retroviral transduction. Among the methods that we tested, we... -
Bile Acid Inhibition of N-type Calcium Channel Currents from Sympathetic Ganglion Neurons
HyeKyungLee, KyoungHwaLee, Eui-SicCho 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.1 4 25-30 (6 pages)
Under some pathological conditions as bile flow obstruction or liver diseases with the enterohepatic circulation being disrupted, regurgitation of bile acids into the systemic circulation occurs and the plasma level of bile acids increases. Bile acids in circulation may affect the nervous system. We examined this possibility by studying the effects of bile acids on gating of neuronal (N)-type Ca2＋ channel that is essential for neurotransmitter release at synapses of the peripheral and central... -
Stem Cells in Drug Screening for Neurodegenerative Disease
Hyun-JungKim, ChangYunJin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.1 1 1-9 (9 pages)
Because the average human life span has recently increased, the number of patients who are diagnosed with neurodegenerative diseases has escalated. Recent advances in stem cell research have given us access to unlimited numbers of multi-potent or pluripotent cells for screening for new drugs for neurodegenerative diseases. Neural stem cells (NSCs) are a good model with which to screen effective drugs that increase neurogenesis. Recent technologies for human embryonic stem cells (ESCs) or induced... -
Functional Expression of TRPV4 Cation Channels in Human Mast Cell Line (HMC-1)
KyungSooKim, DongHoonShin, JooHyunNam, KyungSunPark, YinHuaZhang, WooKyungKim, SungJoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.6 11 419-425 (7 pages)
Mast cells are activated by specific allergens and also by various nonspecific stimuli, which might induce physical urticaria. This study investigated the functional expression of temperature sensitive transient receptor potential vanilloid (TRPV) subfamily in the human mast cell line (HMC-1) using whole-cell patch clamp techniques. The temperature of perfusate was raised from room temperature (RT, 23∼25oC) to a moderately high temperature (MHT, 37∼39oC) to activate TRPV3/4, a high temperature... -
Inhibition of Arterial Myogenic Responses by a Mixed Aqueous Extract of Salvia Miltiorrhiza and Panax Notoginseng (PASEL) Showing Antihypertensive Effects
EunBokBaek, HaeYoungYoo, SuJungPark, Young-ShinChung, Eun-KyungHong, SungJoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.4 4 287-293 (7 pages)
The dried roots of Danshen (Salvia miltiorrhiza) and Sanchi (Panax notoginseng) have been widely used in traditional Chinese medicine for promoting blood circulation as well as various other bodily functions. Here we investigated the effects of a mixture of aqueous extracts of Danshen and Sanchi, named PASEL, on blood pressure and vascular contractility in rats. Orally administered PASEL (62.5 mg/kg and 250 mg/kg, for 5 weeks) lowered the blood pressure of spontaneous hypertensive rats (SHR) but... -
Oxidized Low-density Lipoprotein- and Lysophosphatidylcholine-induced Ca2＋ Mobilization in Human Endothelial Cells
MoonYoungKim, GuoHuaLiang, JiAeeKim, SooSeungChoi, ShinkuChoi, SukHyoSuh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.1 5 27-32 (6 pages)
was further enhanced by OxLDL or by LPC. Increased SOC by OxLDL or by LPC was inhibited by U73122. In voltage-clamped cells, OxLDL or LPC increased [Ca2＋]i and simultaneously activated non-selective cation (NSC) currents. LPC-induced NSC currents were inhibited by 2-APB, La3＋ or U73122, and NSC currents were not activated by LPC in the presence of tempol. Furthermore, in voltage-clamped HUVECs, OxLDL enhanced SOC and evoked outward currents simultaneously. Clamping intracellular Ca2＋ to 1... -
Buffering Contribution of Mitochondria to the [Ca2+]i Increase by Ca2+ Influx through Background Nonselective Cation Channels in Rabbit Aortic Endothelial Cells
YoungChulKim, SangJinLee, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.1 5 29-36 (8 pages)
To prove the buffering contribution of mitochondria to the increase of intracellular Ca2+ level ([Ca2+]i) via background nonselective cation channel (background NSCC), we examined whether inhibition of mitochondria by protonophore carbonylcyanide m-chlorophenylhydrazone (CCCP) affects endothelial Ca2+ entry and Ca2+ buffering in freshly isolated rabbit aortic endothelial cells (RAECs). The ratio of fluorescence by fura-2 AM (R340/380) was measured in RAECs. Biological state was checked by... -
Increase of Intracellular Ca2+ Concentration Induced by Lysophosphatidylcholine in Murine Aortic Endothelial Cells
MeiHongZhu, SungJinPark, HyunJinKim, DongKiYang, SukHyoSuh, InsukSo, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2002, Vol.6 No.2 5 93-100 (8 pages)
Effects of oxidized low-density lipoprotein (ox-LDL), l-α-stearoyl-lysophosphatidylcholine (LPC), on intracellular Ca2 concentration were examined in mouse endothelial cells by measuring intracellular Ca2 concentration ([Ca2]i) with fura 2-AM and reverse transcription-polymerase chain reaction (RT-PCR). LPC increased [Ca2]i under the condition of 1.5 mM [Ca2]o but did not show any effect under the nominally Ca2-free condition. Even after the store... -
The Protective Effect of Melatonin Administration against Adriamycin-induced Cardiotoxicity in Rats
JinHan, ChungheeKim, NariKim, JuheePark, YoungchurlYang, EuiyongKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.4 6 333-342 (10 pages)
Adriamycin is a commonly used chemotherapeutic agent for cancer, including acute leukemia, lymphoma, and a number of solid human tumors. However, recent studies have recognized severe cardiotoxicity after an acute dose, which are likely the result of generation of free radicals and lipid peroxidation. Therefore, the clinical uses of adriamycin have been limited. Melatonin, the pineal gland hormone known for its ability to modulate circardian rhythm, has recently been studied in its several... -
Differentiation of Neuroepithelial Progenitor Cells Implanted into Newborn Rat Brain Striatum
SungChoonKwon, JungSunPark, JeanJuLee, TaickSangNam, DongSooYeon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.1 2 9-17 (9 pages)
It has been demonstrated that multipotent neuronal progenitor cells can be isolated from the developing or adult CNS and proliferated in vitro in response to epidermal growth factor. The present study was undertaken to investigate the differentiation of neuronal progenitor cells after transplantation into the neonatal rat forebrain striatum. Primary cultured progenitor cells were labeled with 3,3'-dioctadecycloxacarbonyl- amine perchlorate (DiO). DiO labeled progenitor cells were implanted into... -
Characteristics of Ca2+ Stores in Rabbit Cerebral Artery Myocytes
SungJoonKim, JinKyungKim, InsukSo, SukHyoSuh, SangJinLee, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.3 6 313-322 (10 pages)
In a myocyte freshly isolated from rabbit cerebral artery, the characteristics of Ca2 release by histamine or caffeine were studied by microspectrofluorimetry using a Ca2-binding fluorescent dye, fura-2. Histamine (5 ㄍM) or caffeine (10 mM) induced a phasic rise of cytoplasmic free Ca2 concentration ([Ca2]c) which could occur repetitively with extracellular Ca2 but only once or twice in Ca2-free bathing solution. Also, the treatment with...
