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전체 선택해제
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본문검색 결과만 보기
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Transverse Vibration of a Uniform Euler-Bernoulli Beam Under Varying Axial Force Using Differential Transformation Method
Shin. Young-Jae, Yun. Jong-Hak 대한기계학회 Journal of mechanical science and technology 6 Pages
대한기계학회 Journal of mechanical science and technology 2006, Vol.20 No.2 191-196 (6 pages)
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Continuous straight archwire에 의하여 발생하는 force system의 분석
최광철(Kwang-Chul Choy), 손병화(Byung Hwa Sohn) 대한치과교정학회 The Korean Journal of Orthodontics 10 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1996, 제 26권 제 3호 6 281-290 (10 pages)
이에 본 연구는 linear beam theory를 도입하여 full arch에 straight wire가 장착된 경우 geometry(a/b), 재질, 단면의 모양, interbracket distance에 관계없이 발생 가능한 모든 상태를 설명할 수 있는 식을 유도하고 일례의 분석을 통하여 다음과 같은 결과를 얻었다. 1. Bilateral fixed beam의 양끝에서 발생하는 force system을 알 수 있는 계산식을 얻었다. 2. 이를 이용하여 continuous straight archwire가 장착된 경우 각 치아에 발생하는 force system을 알 수 있다. 3. Continuous straight archwire장착시 영구변형의... -
A multiple scales method solution for the free and forced nonlinear transverse vibrations of rectangular plates
Shooshtari. A., Khadem. S.E. 테크노프레스 Structural engineering and mechanics : An international journal 18 Pages
테크노프레스 Structural engineering and mechanics : An international journal 2006, Vol.24 No.5 543-560 (18 pages)
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Comparative Study of Stator Core Composition in Transverse Flux Rotary Machine
Lee. Ji-Young, Moon. Seung-Ryul, Koo. Dae-Hyun, Kang. Do-Hyun, Lee. Geun-Ho, Hong. Jung-Pyo 대한전기학회 Journal of electrical engineering & technology 6 Pages
대한전기학회 Journal of electrical engineering & technology 2011, Vol.6 No.3 350-355 (6 pages)
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슬링 뉴렉 기법이 교각 운동 시 몸통 근육과 넙다리뒤근육의 근 활성도에 미치는 영향
하용목, 오재섭, 안덕현, 김미현 한국임상움직임치료학회 한국임상움직임치료학회지 9 Pages
한국임상움직임치료학회 한국임상움직임치료학회지 2021, 제 1권 제 1호 4 25-33 (9 pages)
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Effects of foot pressure using the elastic band with rings during sit-to-stand in persons with stroke
Young-In Hwang, Ki-Song Kim 물리치료재활과학회 Physical Therapy Rehabilitation Science 5 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2017, 제 6권 제 4호 1 159-163 (5 pages)
Objective: Persons with stroke have a tendency to exhibit asymmetric weight-bearing during sit-to-stand because due to the attempt to support themselves with the non-paretic foot. However, there are few devices that can assist with sit-to-stand (STS) performance. This study was designed to investigate the use of the elastic band with rings (EBR) in improving weight-bearing effectively in persons with stroke during STS training. Design: Cross-sectional study. Methods: Thirteen stroke survivors... -
Changes of abdominal muscle thickness during stable and unstable surface bridging exercise in young people
Tae Hoon Kim, Joo-hee Hahn, Ju-Ri Jeong, Chang-joo Lee, You Jin Kim, Sung Min Choi, Da Young Jeon, Jin Hwa Lee, In-Hyuk Lim, Wan-Hee Lee 물리치료재활과학회 Physical Therapy Rehabilitation Science 5 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2016, 제 5권 제 4호 8 210-214 (5 pages)
Objective: The aim of this study was to measure the muscle architectural parameters of abdominal muscles in healthy individuals by rehabilitative ultrasound imaging (RUSI) and to investigate their changes after bridging exercise in various environments. Design: Cross-sectional study. Methods: The study included 40 healthy participants (19 men, 21 women). Subjects were randomly allocated to a stable surface group (SG, n=20) or an unstable surface group (UG, n=20). The participants assumed three... -
Gait analysis on the condition of arm swing in healthy young adults
Hyun-Min Koo, Su-Young Lee 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2016, 제 5권 제 3호 7 149-154 (6 pages)
Objective: The arm swing is associated with gait ability in healthy young adults. The purpose of this study was to examine the effects of arm swing during gait in healthy young adults. Design: Cross-sectional study. Methods: Forty-five subjects without any orthopedic or neurological injuries participated in this study. All subjects performed all three conditions according to the arm swing type as follows: first procedure (condition 1), walking as usual without arm swing constraint; second... -
Comparison on postural control between abdominal draw-in maneuver and abdominal expansion maneuver in persons with stroke
Ho-Suk Choi, Yu-Jin Shim, Won-Seob Shin 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2016, 제 5권 제 3호 1 113-119 (7 pages)
Objective: The effect of abdominal expansion maneuver (AEM) and abdominal draw-in maneuver (ADIM) on postural control in an unsupported position in stroke patients. Design: Randomized controlled trial. Methods: A total of 36 persons with hemiplegic stroke participated in this study. The subjects were randomly divided into an AEM experimental group (n=12), an experimental ADIM group (n=12), and a control group (n=12). We collected the general characteristics of all subjects and the pre-test... -
Comparison of multifidus and external oblique abdominis activity in standing position according to the contraction patterns of the gluteus maximus
Hyuk-Soon Choi, Su-Young Lee 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2016, 제 5권 제 1호 7 40-46 (7 pages)
Objective: The purpose of this study was to examine the effect on multifidus and external oblique abdominis muscle activation during hip contraction of three types (concentric, isometric, eccentric) in standing position. Design: Cross-sectional study. Methods: Twenty healthy adult men volunteered to participate in this study. Muscle activation was recorded from gluteus maximus, both multifidus, and both external oblique abdominis by surface electromyography (EMG) while holding position in the... -
Effects of balance imagery of semi-tandem stance on a flat floor and balance beam for postural control
Jeong-Weon Lee, Su-jin Hwang 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2015, 제 4권 제 2호 5 87-93 (7 pages)
Objective: Balance is a preceding task for functional activities in daily activities as well as community-dwelling activities. To learn skilled and functional activities, it is also necessary to imagine an appropriate and effective movement representation used to plan and execute the functional activities. The purpose of this study was to evaluate the effects of balance imagery of semi-tandem stance on a flat floor and balance beam on balance abilities for elderly and young adults. Design:... -
Correlation between lateral abdominal, rectus femoris, and triceps brachii muscle thickness and endurance during prone bridge exercise in healthy young adults
Kyeong Bong Lee, Jong Geun Kim, Han Gi Park, Ji Eun Kim, Hye Sun Kim, Wan Hee Lee 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2015, 제 4권 제 1호 2 11-16 (6 pages)
Objective: Prone bridge exercise is one of the core strengthening exercise for improving abdominal, lower and upper extremity muscles. In addition, coactivation of the trunk muscles and extremities is important for treatment of low back pain. This study aimed to investigate the correlation between the thickness, cross-sectional area of the target muscle, and endurance during prone bridge exercise. Our hypothesis was that an increase in muscle thickness is positively related to the hold time for... -
The effect of co-contraction exercises of abdominal bracing combined with ankle dorsiflexion on abdominal muscle thickness and strength in patients with chronic low back pain
Wenlan Chai, So Hee Lee, Yu Hyung Park 물리치료재활과학회 Physical Therapy Rehabilitation Science 8 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2014, 제 3권 제 2호 3 93-100 (8 pages)
of three weeks, respectively. All the subjects were evaluated for abdominal muscle thickness and strength before and after intervention using ultrasonography and MedX machine. Results: The external oblique (EO), internal oblique, transverse abdominis (TrA) muscle thickness and the strength produced at 48°, 60°, 72° showed a significant increase in the ABDF group after intervention, with a more significant improvement in EO and TrA muscle thickness in the ABDF group compared with the AB group... -
The changes of rectus abdominis muscle thickness according to the angle during active straight leg raise
Hwang Jae Lee, Kil Ho Shin, Sung Mi Byun, Hyeon Seo Jeong, Ji Su Hong, Su Ji Jeong, Wan Hee Lee 물리치료재활과학회 Physical Therapy Rehabilitation Science 5 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2013, 제 2권 제 1호 8 44-48 (5 pages)
Objective: The purpose of this study was to investigate changes of abdominal muscles thickness according to the angle during the active straight leg raise (ASLR) in young healthy subjects. Design: Cross sectional study. Methods: Twenty-three healthy university students (13 men and 10 women) voluntary participated to the study in S University. The ASLR was performed with the subject lying supine with lower extremities straight on a standard plinth, hands resting on the chest, and elbows on the... -
A study to evaluate the effects of ultraviolet blood irradiation in a diabetic rabbit model
Gareeballah Osman Adam, Gi Beum Kim, Jin Ryong Park, Kyung Min Choi, Gwan Seob Shim, Shang Jin Kim, Jin Shang Kim, Hyung Sub Kang 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 269 339-340 (2 pages)
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Echocardiographic assessment of coronary artery flow in normal canines and model dogs with myocardial infarction
Nohwon Park, Jaehwan Kim, Miyoung Lee, Soyun Lee, Sunhye Song, Seungjun Lee, Soyoung Kim, Yangwoo Park, Kidong Eom* 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 1호 17 149-155 (7 pages)
This study was conducted to evaluate the usefulness of coronary arterial profiles from normal dogs (11 animals) and canines (six dogs) with experimental myocardial infarction (MI) induced by ligation of the left coronary artery (LCA). Blood velocity of the LCA and right coronary artery (RCA) were evaluated following transthoracic pulsed-wave Doppler echocardiography. The LCA was observed as an infundibular shape, located adjacent to the sinus of Valsalva. The RCA appeared as a tubular structure... -
Evaluation of a canine small intestinal submucosal xenograft and polypropylene mesh as bioscaffolds in an abdominal full-thickness resection model of growing rats
A-Jin Lee, Sung-Ho Lee, Wook-Hun Chung, Dae-Hyun Kim, Dai-Jung Chung, Sun Hee Do, Hwi-Yool Kim* 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2013, 제 14권 제 2호 9 175-184 (10 pages)
We evaluated the biological scaffold properties of canine small intestinal submucosa (SIS) compared to a those of polypropylene mesh in growing rats with full-thickness abdominal defects. SIS is used to repair musculoskeletal tissue while promoting cell migration and supporting tissue regeneration. Polypropylene mesh is a non-resorbable synthetic material that can endure mechanical tension. Canine SIS was obtained from donor German shepherds, and its porous collagen fiber structure was... -
Activation of Akt/protein kinase B mediates the protective effects of mechanical stretching against myocardial ischemia-reperfusion injury
Chan-Hyung Kim*, Jia Hao, Hee-Yul Ahn, Si Wook Kim* 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2012, 제 13권 제 3호 4 235-244 (10 pages)
Akt/protein kinase B is a well-known cell survival factor and activated by many stimuli including mechanical stretching. Therefore, we evaluated the cardioprotective effect of a brief mechanical stretching of rat hearts and determined whether activation of Akt through phosphatidylinositol 3-kinase (PI3K) is involved in stretch-induced cardioprotection (SIC). Stretch preconditioning reduced infarct size and improved post- ischemic cardiac function compared to the control group. Phosphorylation of... -
Computed tomographic characteristics of acute thoracolumbar intervertebral disc disease in dogs
Changyun Lim, Oh-Kyeong Kweon, Min-Cheol Choi, Jihye Choi, Junghee Yoon, * 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2010, 제 11권 제 1호 11 73-79 (7 pages)
Forty canine patients with a presumptive diagnosis of the intervertebral disc herniation at the thoracolumbar region were imaged. A neurological examination was performed and all patients were classified under four grades by the examination. The degrees of attenuation of the herniated disc material were measured in Housefield units (HU) in each image. The ratio of the area to herniated disc material and the height to disc material were measured. The clinical grade was correlated with the area... -
Canine model of ischemic stroke with permanent middle cerebral artery occlusion: clinical and histopathological findings
Byeong-Teck Kang, Jong-Hwan Lee, Dong-In Jung, Chul Park, Su-Hyun Gu, Hyo-Won Jeon, Dong-Pyo Jang, Chae-Young Lim, Fu-Shi Quan, 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 4호 9 369-376 (8 pages)
The aim of the present study was to assess the clinical and histopathological findings in a canine model of ischemic stroke. Cerebral ischemic stroke was induced by middle cerebral artery occlusion in four healthy beagle dogs using silicone plugs. They showed neurological signs of forebrain dysfunction such as reduced responsiveness, head turning, circling, postural reaction deficits, perceptual deficits, and hemianopsia. These signs gradually regressed within 4 weeks without therapy. On... -
Epigallocatechin-3 gallate prevents cardiac hypertrophy induced by pressure overload in rats
Jia Hao, Chan-Hyung Kim, Tae-Sun Ha, Hee-Yul Ahn 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 2호 4 121-129 (9 pages)
suprarenal transverse abdominal aortic constriction (AC) in rats. Three weeks after AC surgery, heart to body weight ratio increased in the AC group by 34% compared to the sham group. EGCG administration suppressed the load-induced increase in heart weight by 69%. Attenuation of cardiac hypertrophy by EGCG was associated with attenuation of the increase in myocyte cell size and fibrosis induced by aortic constriction. Despite abolition of hypertrophy by EGCG, transstenotic pressure gradients did... -
Original Article : Anatomy of the diaphyseal nutrient foramen in the long bones of the pectoral limb of German Shepherds
Jeoung Ha Sim , Dong Choon Ahn 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 6 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2014, 제 54권 제 3호 8 179-184 (6 pages)
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Displacement and stress distribution of the maxillofacial complex during maxillary protraction using palatal plates
Jusuk Eom, Mohamed Bayome, Jae Hyun Park, Hee Jin Lim, Yoon-Ah Kook, Seong Ho Han 대한치과교정학회 The Korean Journal of Orthodontics 12 Pages
대한치과교정학회 The Korean Journal of Orthodontics 2018, 제 48권 제 5호 4 304-315 (12 pages)
and F, transverse expansion was performed simultaneously with maxillary protraction. Results: Type C displayed the greatest amount of anterior dentoskeletal displacement in the sagittal plane. Types A and B resulted in similar amounts of anterior displacement of all the maxillofacial landmarks. Type D showed little movement, but Type E with expansion and the palatal plate displayed a larger range of movement of the maxillofacial landmarks in all directions. Conclusions: The palatal plate served... -
The effects of posterior retraction on the displacement of the maxilla
Bo-Yeong Yoo, Jong-Chul Kim 대한치과교정학회 The Korean Journal of Orthodontics 13 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1996, 제 26권 제 6호 5 691-703 (13 pages)
class II malocclusion. The retraction force of 400g was applied to the first molar. The direction of the force application was 23° downward, parallel, 23° upward and 45` upward to the occlusal plane. The stress distribution and the displacement within the maxilla were analyzed by three-dimensional finite element method. The findings obtained were as follows: 1. Maxillary first molar was displaced posteriorly and inferiorly in 23° downward, parallel, 23° upward retraction but it was displaced... -
상악 전치 intrusion 시 저항중심의 위치에 관한 3차원 유한요소법적 연구
박춘근(Chun-Keun Park), 양원식(Won-Sik Yang) 대한치과교정학회 The Korean Journal of Orthodontics 14 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1997, 제 27권 제 2호 8 259-272 (14 pages)
Segmented arch mechanics를 적용하여 상악 전치에 intrusive force를 가할 때 저항중심의 전후방 위치를 알아내기 위해 상악 6전치와 치근막 및 치조골의 3차원 유한요소모델을 제작하였다. Intrusion시키고자 하는 치아의 수, 치축의 경사도 및 치조골의 흡수 정도에 따른 저항중심의 위치변화를 비교 관찰하여 다음과 같은 결과를 얻었다. 1. 치축 경사도와 치조골의 높이가 정상일 경우, 치아의 수에 따른 저항중심부의 위치는 다음과 같았다. 1) 중절치 2개를 대상으로 한 경우에는 측절치 브라켓의 원심면 부위에 위치하였다. 2)... -
Camouflage Extraction Treatment of Unilateral Cleft Lip and Palate Patient: 4-year Follow-up
Woowon Jang, Jueon Song, Soonshin Hwang, Chooryung J. Chung, Kyung-Ho Kim 대한구순구개열학회 대한구순구개열학회지 7 Pages
대한구순구개열학회 대한구순구개열학회지 2019, 제 22권 1호 6 33-39 (7 pages)
Cleft lip and palate is one of the most common congenital abnormalities in the dentofacial region. Orthodontic treatment for adult patients with cleft lip and palate is difficult because of several factors such as dental anomalies, limitations in tooth movement around the cleft region, and retention. Here we report a case involving a 20-year-old woman with unilateral cleft lip and palate who successfully underwent camouflage orthodontic treatment for skeletal Class II malocclusion accompanied by... -
구순구개열 환자에서 급속 구개 확장술에 대한 고찰
김민진, 안장훈, 조영석, 안소미, 김주원 대한구순구개열학회 대한구순구개열학회지 9 Pages
대한구순구개열학회 대한구순구개열학회지 2014, 제 17권 1호 6 45-53 (9 pages)
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Spatial reproducibility of complex fractionated atrial electrogram depending on the direction and configuration of bipolar electrodes: an in-silico modeling study
Jun-SeopSong, Young-SeonLee, MinkiHwang, Jung-KeeLee, ChangyongLi, BoyoungJoung, Moon-HyoungLee, EunBoShim, Hui-NamPak 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.5 8 507-514 (8 pages)
Although 3D-complex fractionated atrial electrogram (CFAE) mapping is useful in radiofrequency catheter ablation for persistent atrial fibrillation (AF), the directions and configuration of the bipolar electrodes may affect the electrogram. This study aimed to compare the spatial reproducibility of CFAE by changing the catheter orientations and electrode distance in an in -silico left atrium (LA). We conducted this study by importing the heart CT image of a patient with AF into a 3D-homogeneous... -
Lamotrigine Decreased Hippocampal Damage and Improved Vascular Risk Markers in a Rat Model of Pentylenetetrazole Induced Kindling Seizure
BasmaSHaggag, AmanyHHasanin, MonaHRaafat, HalaSAbdelKawy 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.3 11 269-278 (10 pages)
Various antiepileptic drugs (AEDs) especially enzyme-inducing AEDs might be associated with increased vascular risk, through impairment of the endogenous antioxidative ability which may trigger oxygen-dependent tissue injury. Lamotrigine (LTG) a non-enzyme-inducing AED has scarce information regarding its effects on oxidative stress. The present study aimed to study the possible modulation of vascular risk factors of epileptogenesis by LTG, in a rat model of kindling seizure induced by... -
Effects of Treadmill Exercise on the Recovery of Dopaminergic Neuron Loss and Muscle Atrophy in the 6-OHDA Lesioned Parkinson's Disease Rat Model
Myoung-AeChoe, Byung-SooKoo, GyeongJuAn, SongheeJeon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.5 3 305-312 (8 pages)
This study was to determine the effect of exercise on the recovery of dopaminergic neuron loss and muscle atrophy in 6-OHDA-induced hemi Parkinson's disease model. Exercise was loaded twice per day for 30 minutes each time, at 5 days after 6-OHDA lesioning and continued for 16 days using a treadmill. Exercise significantly increased the number of tyrosine hydroxylase positive neuron in the lesioned substantia nigra and the expression level of tyrosine hydroxylase in the striatum compared with... -
Mechanical Stretch-Induced Protection against Myocardial Ischemia- Reperfusion Injury Involves AMP-Activated Protein Kinase
JiaHao, Hun-SikKim, WoongChoi, TaeSunHa, Hee-YulAhn, Chan-HyungKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.1 1 1-9 (9 pages)
AMP-activated protein kinase (AMPK) protects various tissues and cells from ischemic insults and is activated by many stimuli including mechanical stretch. Therefore, this study investigated if the activation of AMPK is involved in stretch-induced cardioprotection (SIC). Intraventricular balloon and aorto-caval shunt (ACS) were used to stretch rat hearts ex vivo and in vivo, respectively. Stretch preconditioning reduced myocardial infarct induced by ischemia-reperfusion (I/R) and improved... -
腦影像術을 通한 腦의 形態學的 分析 方法論 硏究
김주한, 이정희, 우종인 대한신경정신의학회 신경정신의학 12 Pages
대한신경정신의학회 신경정신의학 1995, 제 34권 제 4호 24 1204-1215 (12 pages)
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n-Alkanols가 소의 대뇌피질로부터 분리한 Synaptosomal Plasma Membrane Vesicles의 측방확산운동 범위와 속도에 미치는 영향
정인교(In-Kyo Chung), 강정숙(Jung-Sook Kang), 윤일(Il Yun) 대한약리학회 대한약리학잡지 8 Pages
대한약리학회 대한약리학잡지 1993, 제 29권 제 1호 16 157-164 (8 pages)
n-Alkanols의 분자적 약리작용기전 탐구에 기초자료를 제공하기 위하여 소의 신선한 대뇌피질로부터 분리한 synaptosomal plasma membrane vesicles (SPMV) 지질 이중층의 측방확산운동에 미치는 n-alkanols의 영향을 형광 probe법으로 검색하였다. n-Alkanols는 SPMV 지질 이중층의 측방확산운동 범위와 속도를 농도 의존적으로 증가시켰고 1-nonanol까지는 탄소수가 두개 증가될 때마다 그 효력은 약 10배 가량 증가되었으나 탄소수 10개인 1-decanol의 효력은 오히려 감소되는 경향을 나타내었다. -
GS354, GS389: 새로운 칼슘 길항제
장기철(Ki Churl Chang), 손동렬(Dong-Ryul Sohn), 정원석(Won Seog Chong), 정수연(Soo Youn Chung), 이영수(Young Soo Lee), 김시환(Si Hwan Kim), 노홍기(Hong Kee 대한약리학회 대한약리학잡지 8 Pages
대한약리학회 대한약리학잡지 1991, 제 27권 제 1호 6 45-52 (8 pages)
GS354와 GS389의 세포내 칼슘{[Ca2+]1: Fura-2의 형광으로 측정}과 근장력 변화에 대하여 백서의 흉부동맥을 사용하여 검토하였다. GS354와 GS389 모두 고농도의 포타슘과 노어에피네프린에 의한 수축을 억제시켰다. GS354의 헐관이완은 [Ca2+]1의 감소가 동반되었고 고농도의 포타슘에 의한 [Ca2+]1증가억제 현상도 칼슘통로 활성제인 Bay K8644에 의하여 길항되었다. 그러나 혈관이완 작용은 Bay K8644에 의해 억제 되지 않았다. 이러한 사실은 GS354는 칼슘통로를 차단하여 [Ca2+]1을 감소시키며 또한 수축기구에 대한 칼슘의 감수성을... -
Role of Na+-K+ Pump on Endothelium-dependent Relaxation
Sung, Sang-Hyun, Roh, Joon-Ryang, Park, Tae-Sic, Suh, Suk-Hyo, Hwang, Sang-Ik, Kim, Ki-Whan 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1993, 제 27권 제 2호 8 199-208 (10 pages)
To study the underlying mechanism through which the endothelium-dependent relaxation is inhibited by blocking the Na+ -K+ pump, the effects of Na+ -K+ pump blockade on the release of EDRF and its relaxing activity were examined, using organ bath study, bioassay technique, and cGMP measurement. Endothelium-dependent relaxation was attenuated by blocking the Na+ -K+ pump in the vascular ring with intact endothelium. In bioassay experiment EDRF release was decreased with the blockade of the Na+... -
토끼 대동맥 평활근의 내피세포 의존성 이완에 미치는 Ca2+ 및 Ca2+ 길항제의 효과
서석효(Suh, Suk-Hyo), 구용숙(Goo, Yong-Sook), 박춘옥(Park, Choon-Ok), 황상익(Hwang, Sang-Ik), 김기환(Kim, Ki-Whan) 대한생리학회 대한생리학회지 12 Pages
대한생리학회 대한생리학회지 1990, 제 24권 제 1호 8 91-102 (12 pages)
토끼 흉부 대동맥을 이용하여 내피세포 의존성 혈관이완에 대한 세포외 Ca2+과 여러가지 Ca2+ 길항제의 효과를 분석하여 EDRF의 작용기전을 밝혀 보고자 하였다. 대동맥 횡단 절편의 등장성 수축은 10-7 M 노에피네프린으로 유발시켰으며, 10-6 M 사세틸콜린으로 내피세포 의존성 혈관이완을 일으켰다. 내피세포는 작은 솜뭉치로 부드럽게 문질러서 제거하였으며, hemolysate를 사용하여 EDRF에 대한 헤모글로빈의 효과를 관찰하였다. 결과를 종합하면 다음과 같다. 1) 아세틸콜린에 의한 내피세포 의존성 혈관이완은 두 시기, 즉...
