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Mutations of p53 Tumor Suppressor Gene in Spontaneous Canine Mammary Tumors
Chung-Ho Lee and Oh-Kyeong Kweon 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 4호 10 321-325 (5 pages)
the p53 gene for mutations in 20 spontaneous canine mammary tumors using polymerase chain reaction (PCR) with direct sequence analysis to evaluate the role of this gene in canine mammary tumorigenesis and analyzed to compare with other clinicopathological parameters including age, histology, stage, recurrence and death from tumor. Four missense (one case had two missense mutations) and one nonsense mutations were detected in 10 malignant lesions (40%), and two missense and one silent mutations... -
Identification of Novel Mutations In Adenosine Deaminase Gene In Korean Leukemia Patients
박기호, Park. Ki-Ho 한국생명과학회 생명과학회지 4 Pages
한국생명과학회 생명과학회지 2010, Vol.20 No.3 453-456 (4 pages)
백혈병은 조혈모세포의 비정상적인 증식에 의해 일어나서 질환이고, adenosine deaminase (ADA) 유전자는 백혈병의 약물 작용점으로 중요하다. 이러한 연구의 일환으로 한국인 백혈병 환자 20명의 ADA 유전자의 변이를 조사하기 위해 혈액 genomice DNA를 추출하여 염기서열을 결정하였다. 그 결과 nonsense 변이인 F101F 하나, missense 변이 E260K, D8Y 각각 하나, 그리고 외국에서는 보고되지 않은 것으로 정상인에서 IVS6-52 에 GC가 도입된 것을 확인하였다. 백혈병 환자와 유전자 변이간에 통계학적인 차이점은 없지만 이러한... -
The Mutation of a Novel Saccharomyces cerevisiae SRL4 Gene Rescues the Lethality of rad53 and lcd1 Mutations by Modulating dNTP Levels
Choi. Do-Hee, Oh. Young-Mi, Kwon. Sung-Hun, Bae. Sung-Ho 한국미생물학회 The journal of microbiology 6 Pages
한국미생물학회 The journal of microbiology 2008, Vol.46 No.1 75-80 (6 pages)
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Gene Mutations of 23S rRNA Associated with Clarithromycin Resistance in Helicobacter pylori Strains Isolated from Korean Patients
Kim. Jung-Mogg, Kim. Joo-Sung, Kim. Na-Young, Kim. Yeoung-Jeon, Kim. In-Young, Chee. Young-Joon, Lee. Chul-Hoon, Jung. Hyun-Chae 한국미생물생명공학회 Journal of microbiology and biotechnology 6 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 2008, Vol.18 No.9 1584-1589 (6 pages)
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Characterization of Mutations in AlHK1 Gene from Alternaria longipes: Implication of Limited Function of Two-Component Histidine Kinase on Conferring Dicarboximide Resistance
Luo. Yiyong, Yang. Jinkui, Zhu. Mingliang, Yan. Jinping, Mo. Minghe, Zhang. Keqin 한국미생물생명공학회 Journal of microbiology and biotechnology 8 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 2008, Vol.18 No.1 15-22 (8 pages)
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Effects of Mutations in the Regulatory Region on Transcriptional Regulation of glpD Gene
Jeong. Hee-Tae, Choi. Yong-Lark, Chung. Soo-Yeol, Chung. Chung-Han 한국미생물생명공학회 Journal of microbiology and biotechnology 5 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 1995, Vol.5 No.5 245-249 (5 pages)
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Genotype Distribution of the Mutations in the Coagulation Factor V Gene in the Korean Population: Absence of Its Association with Coronary Artery Disease
Hong. Seung-Ho 한국동물학회 Korean journal of biological sciences 5 Pages
한국동물학회 Korean journal of biological sciences 2003, Vol.7 No.3 255-259 (5 pages)
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Characterization of the Acetolactate synthase (ALS) gene and Molecular Assay of Mutations Associated with Sulfonylurea Herbicide Resistance of Monochoria vaginalis
박태선, 박홍규, 구본일, 김영두, 고재권, 이인용, 박재읍, Park. Tae-Seon, Park. Hong-Kyu, Ku. Bon-Il, Kim. Young-Doo, Ko. Jae-Kwon, Lee. In-Yong, Park. Jae-Eup 한국농약과학회 농약과학회지 8 Pages
한국농약과학회 농약과학회지 2009, Vol.13 No.4 290-297 (8 pages)
본 연구는 한국에서 발생하고 있는 설포닐우레아계 제초제 저항성 및 감수성 물달개비의 ALS 염기서열 분석에 의한 ALS 유전자의 특성과 제초제 저항성 메카니즘을 구명하기 위하여 실시하였다. 감수성 및 저항성 두 계통의 biotype에서 815개의 염기서열을 분석하였다. 분석된 염기서열에서 감수성 biotype으로부터 4개 clone, 저항성 계통으로부터 15개 clone, 총 19개의 clone들을 크게 4 group으로 분류할 수 있었다. 첫 번째 group은 저항성 및 감수성 biotype의 ALS 유전자 염기서열이 차이가 없었으며, 두 번째 그룹은 아미노산... -
No Effect of High Fat Diet-Induced Obesity on Spontaneous Reporter Gene Mutations in gpt Delta Mice
Takasu. Shinji, Ishii. Yuji, Matsushita. Kohei, Kuroda. Ken, Kijima. Aki, Kodama. Yukio, Ogawa. Kumiko, Umemura. Takashi 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 4 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2014, Vol.15 No.17 7149-7152 (4 pages)
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Lack of Mutations in Protein Tyrosine Kinase Domain Coding Exons 19 and 21 of the EGFR Gene in Oral Squamous Cell Carcinomas
Mehta. Dhaval Tushar, Annamalai. Thangavelu, Ramanathan. Arvind 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 5 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2014, Vol.15 No.11 4623-4627 (5 pages)
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BRCA1 Gene Exon 11 Mutations in Uighur and Han Women with Early-onset Sporadic Breast Cancer in the Northwest Region of China
Cao. Yu-Wen, Fu. Xin-Ge, Wan. Guo-Xing, Yu. Shi-Ying, Cui. Xiao-Bin, Li. Li, Jiang. Jin-Fang, Zheng. Yu-Qin, Zhang. Wen-Jie, Li. Feng 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 6 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2014, Vol.15 No.11 4513-4518 (6 pages)
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Serum Carcinoembryonic Antigen Levels before Initial Treatment are Associated with EGFR Mutations and EML4-ALK Fusion Gene in Lung Adenocarcinoma Patients
Wang. Wen-Tao, Li. Yin, Ma. Jie, Chen. Xiao-Bing, Qin. Jian-Jun 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 6 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2014, Vol.15 No.9 3927-3932 (6 pages)
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Lack of CHEK2 Gene Mutations in Differentiated Thyroid Carcinoma Patients using High Resolution Melting Analysis
Fayaz. Shima, Fard-Esfahani. Pezhman, Torbati. Peyman Mohammadi 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 4 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2014, Vol.15 No.12 5019-5022 (4 pages)
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High Frequency of TP53 but not K-ras Gene Mutations in Bolivian Patients with Gallbladder Cancer
Asai. Takao, Loza. Ernesto, Roig. Guido Villa-Gomez, Ajioka. Yoichi, Tsuchiya. Yasuo, Yamamoto. Masaharu, Nakamura. Kazutoshi 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 6 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2014, Vol.15 No.13 5449-5454 (6 pages)
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Novel Mutations of the PARP-1 Gene Associated with Colorectal Cancer in the Saudi Population
Alshammari. Atika Hazzaa, Shalaby. Manal Aly, Alanazi. Mohammad Saud, Saeed. Hesham Mahmoud 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 7 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2014, Vol.15 No.8 3667-3673 (7 pages)
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Relationship between Epidermal Growth Factor Receptor Gene Mutations and Clinicopathological Features in Patients with Non-Small Cell Lung Cancer in Western Turkey
Unal. Olcun Umit, Oztop. Ilhan, Calibasi. Gizem, Baskin. Yasemin, Koca. Dogan, Demir. Necla, Akman. Tulay, Ellidokuz. Hulya, Yilmaz. Ahm 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 5 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2013, Vol.14 No.6 3705-3709 (5 pages)
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Genetic Screening for Mutations in the Chip Gene in Intracranial Aneurysm Patients of Chinese Han Nationality
Su. Li, Zhang. Yuan, Zhang. Chun-Yang, Zhang. An-Long, Mei. Xiao-Long, Zhao. Zhi-Jun, Han. Jian-Guo, Zhao. Li-Jun 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 3 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2013, Vol.14 No.3 1687-1689 (3 pages)
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Differences in Epidermal Growth Factor Receptor Gene Mutations and Relationship with Clinicopathological Features in NSCLC Between Uygur and Han Ethnic Groups
Zhang. Yan, Wang. Qiang, Han. Zhi-Gang, Shan. Li 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 5 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2013, Vol.14 No.5 2879-2883 (5 pages)
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Lack of RING Finger Domain (RFD) Mutations of the c-Cbl Gene in Oral Squamous Cell Carcinomas in Chennai, India
Rajendran. Senthilnathan, Muthupalani. Rajendran Shanmugam, Ramanathan. Arvind 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 3 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2013, Vol.14 No.2 1073-1075 (3 pages)
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c-KIT Positive Schistosomal Urinary Bladder Carcinomas are Frequent but Lack KIT Gene Mutations
Shams. Tahany M., Metawea. Mokhtar, Salim. Elsayed I. 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 6 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2013, Vol.14 No.1 15-20 (6 pages)
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Molecular Investigation of Isocitrate Dehydrogenase Gene (IDH) Mutations in Gliomas: First Report of IDH2 Mutations in Indian Patients
Ranjan Das. Bibhu, Tangri. Rajiv, Ahmad. Firoz, Roy. Arnab, Patole. Kamlakar 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 4 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2013, Vol.14 No.12 7261-7264 (4 pages)
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Lack of KRAS Gene Mutations in Chronic Myeloid Leukemia in Iran
Kooshyar. Mohammad Mahdi, Ayatollahi. Hossein, Keramati. Mohammad Reza, Sadeghian. Mohammad Hadi, Miri. Mohsen, Sheikhi. Maryam 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 4 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2013, Vol.14 No.11 6653-6656 (4 pages)
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Absence of P53 Gene Mutations in Exons 5 - 7 Among Breast Cancer Patients of Bengalee Hindu Caste Females, West Bengal, India
Roy. Abhishikta Ghosh, Sarkar. B.N., Roy. Rakesh, Rao. V.R., Bandyopadhyay. A.R. 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 3 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2012, Vol.13 No.9 4477-4479 (3 pages)
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Identification of Novel Compound Heterozygous Mutations in the ACADS Gene of an Asymptomatic Korean Newborn with Short Chain Acyl-CoA Dehydrogenase Deficiency by Tandem Mass Spectrometry
Cheon. Chong-Kun, Choi. Hyung-Soon, Kim. Su-Yung, Yoo. Han-Wook, Kim. Gu-Hwan 대한의학유전학회 Journal of genetic medicine 5 Pages
대한의학유전학회 Journal of genetic medicine 2012, Vol.9 No.1 42-46 (5 pages)
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Somatic Mutations of the ENPP2 (Autotaxin/lysoPLD) Gene in Breast Cancer
Song. Jae-Hwi, Kim. Jeong-Kyu, Noh. Ji-Heon, Jung. Kwang-Hwa, Eun. Jung-Woo, Kim. Chang-Jae, Bae. Hyun-Jin, Xie. Hong-Jian, Ahn. Young-M 대한독성유전단백체학회 Molecular & cellular toxicology 5 Pages
대한독성유전단백체학회 Molecular & cellular toxicology 2007, Vol.3 No.4 262-266 (5 pages)
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Prevalence of Drug Resistance-Associated Gene Mutations in Plasmodium vivax in Central China
Lu. Feng, Wang. Bo, Cao. Jun, Sattabongkot. Jetsumon, Zhou. Huayun, Zhu. Guoding, Kim. Kwonkee, Gao. Qi, Han. Eun-Taek 대한기생충학회 The Korean journal of parasitology 6 Pages
대한기생충학회 The Korean journal of parasitology 2012, Vol.50 No.4 379-384 (6 pages)
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Detection of Novel Oxazolidinone and Phenicol resistance gene optrA in Enterococcal isolates from Food Animals and Animal Carcasses
Migma Tamang, Dong Chan Moon, Su Ran Kim, Hee Young Kang, Ki chan Lee, Hyang Mi Nam, Geum Chan Jang, Hee Soo Lee, Suk Chan Jung, Suk Kyu 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 169 282-283 (2 pages)
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Polymorphism in the serotonin transporter protein gene in Maltese dogs with degenerative mitral valve disease
Chang-Min Lee, Jae-Ik Han, Min-Hee Kang, Seung-Gon Kim, Hee-Myung Park 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 1호 16 129-135 (7 pages)
Degenerative mitral valve disease (DMVD) is the most commonly acquired cardiac disease in dogs. This study evaluated the relationship between genetic variations in the serotonin transporter (SERT) gene of Maltese dogs and DMVD. Genomic DNA was extracted from blood samples collected from 20 client-owned DMVD Maltese dogs and 10 healthy control dogs, and each exon of the SERT gene was amplified via polymerase chain reaction. The resulting genetic sequences were aligned and analyzed for variations... -
Analysis of structure-function relationship in porcine rotavirus A enterotoxin gene
Sharad Saurabh, Shubhankar Sircar, Jobin J. Kattoor, Souvik Ghosh, Nobumichi Kobayashi, Krisztian Banyai, Obli R. VinodhKumar, U 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 1호 6 35-43 (9 pages)
we analyzed the nsp4 gene from porcine RVs isolated from diarrheic and non-diarrheic cases at different levels of protein folding to explore correlations to diarrhea-inducing capabilities and evolution of nsp4 in the porcine population. Full-length nsp4 genes were amplified, cloned, sequenced, and then analyzed for antigenic epitopes, RotaC classification, homology, genetic relationship, modeling of NSP4 protein, and prediction of post-translational modification. RV presence was observed in both... -
Sequence analysis of the spike gene of Porcine epidemic diarrhea virus isolated from South China during 2011-2015
Xiaoya Zhao, Zhili Li, Xiduo Zeng, Guanqun Zhang, Jianqiang Niu, Baoli Sun, Jingyun Ma 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 2호 14 237-243 (7 pages)
The spike gene of porcine epidemic diarrhea virus (PEDV) was sequenced from 55 South China field strains isolated from pigs with symptoms of diarrhea. The sequences were compared within the set of field strains as well as with reference strains available in GenBank. Within the 55 South China PEDV field strains, the deduced amino acid sequence identities ranged from 93.8% to 99.9 % and ranged from 90.7% to 99.5% when compared with the foreign reference strains in GenBank. Our phylogenetic... -
Genomic diversity of the Avian leukosis virus subgroup J gp85 gene in different organs of an infected chicken
Fanfeng Meng, Xue Li, Jian Fang, Yalong Gao, Lilong Zhu, Guiju Xing, Fu Tian, Yali Gao, Xuan Dong, Shuang Chang, Peng Zhao, Zhiz 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 4호 8 497-503 (7 pages)
The genomic diversity of Avian leukosis virus subgroup J (ALV-J) was investigated in an experimentally infected chicken. ALV-J variants in tissues from four different organs of the same bird were re-isolated in DF-1 cells, and their gp85 gene was amplified and cloned. Ten clones from each organ were sequenced and compared with the original inoculum strain, NX0101. The minimum homology of each organ ranged from 96.7 to 97.6%, and the lowest homology between organs was only 94.9%, which was much... -
Isolation and phylogenetic analysis of hemagglutinin gene of H9N2 influenza viruses from chickens in South China from 2012 to 2013
Han-Qin Shen, Zhuan-Qiang Yan, Fan-Gui Zeng, Chang-Tao Liao, Qing-Feng Zhou, Jian-Ping Qin, Qing-Mei Xie, Ying-Zuo Bi, Feng Chen 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 3호 9 317-324 (8 pages)
As part of our ongoing influenza surveillance program in South China, 19 field strains of H9N2 subtype avian influenza viruses (AIVs) were isolated from dead or diseased chicken flocks in Guangdong province, South China, between 2012 and 2013. Hemagglutinin (HA) genes of these strains were sequenced and analyzed and phylogenic analysis showed that 12 of the 19 isolates belonged to the lineage h9.4.2.5, while the other seven belonged to h9.4.2.6. Specifically, we found that all of the viruses... -
Cloning, expression and functional analysis of the duck Toll-like receptor 5 (TLR5) gene
Yuqiang Cheng, Yingjie Sun, Hengan Wang, Shuduan Shi, Yaxian Yan, Jing Li, Chan Ding, Jianhe Sun 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 1호 6 37-46 (10 pages)
the present study, the first TLR5 gene in duck was cloned. The open reading frame (ORF) of duck TLR5 (dTLR5) cDNA is 2580 bp and encodes a polypeptide of 859 amino acids. We also cloned partial sequences of myeloid differentiation factor 88, 2’-5’-oligoadenylate synthetase (OAS), and myxovirus resistance (Mx) genes from duck. dTLR5 mRNA was highly expressed in the bursa of Fabricius, spleen, trachea, lung, jejunum, rectum, and skin; moderately expressed in... -
M gene analysis of canine coronavirus strains detected in Korea
Seok-Young Jeoung, So-Yun Ann, Hyun-Tae Kim, Doo Kim, 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 4호 5 495-502 (8 pages)
Korean strains had homology ranged from 86.3% to 98.3% (89.1% to 99.2% for the amino acid sequence) and 87.7% to 97.8% (92.4% to 100% for the amino acid sequence) when compared to FCoV-like CCV strains (type I). Three amino acid variations in the M gene were characteristic for the Korean CCV strains. Phylogenetic analysis demonstrated that the 22 Korean CCV strains belonged to four typical CCV clusters (i.e., a unique Korean CCV cluster, a type II and transmissible gastroenteritis virus cluster,...


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