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The Action of Acetylcholine on the End-Plate Potential
Koh, Il-Sup 대한생리학회 대한생리학회지 8 Pages
대한생리학회 대한생리학회지 1975, 제 9권 제 2호 6 41-48 (8 pages)
The failure of the action potential at the end-plate membrane to reach the sodium equilibrium potential is due to the stimulating action of acetylcholine on Na+-K+ pump. This action of acetylcholine causes an enormous increase in the K+ transport rate. The quantitative amount of potassium ions in the inside of the end-plate membrane prevented the permeability of sodium ions during the depolarization phase of the action potential. It would favor the changes in the shape of action potential by... -
교정시설에서 종교교육(교화)제도의 개선방안-종교교정위원을 중심으로
한국종교교육학회 종교교육학연구 2020, 제 63권 3 37-54 (18 pages)
범죄인에 대한 교육형주의(敎育型主義)의 수단인 종교교육은 교화에서 가장 유효한 수단으로 널리 활용되어 왔다. 우리나라에서는 구한말에 이승만에 의한 기독교 종교교화가 종교교화의 시초였다. 그 뒤 일제 강점기의 제국주의적 종교교육형주의와 권위주의 정권하의 정치적 종교교육형주의를 거쳐 오늘날은 정치성은 완화되었으나 보수적이고 관료화된 종교교육형주의가 부드럽고 세련되게 지배하고 있다. 우리나라 종교교화의 개선방안을 운론하기에 앞서서 먼저 역사적으로 수용자의 종파별 구성의 변천의 내용과 의미와 종교교화의... -
Comparison of the effects of different-sized airways in inspiratory trainers on maximal inspiratory pressure and rating of perceived exertion scale in healthy young people
Young-In Hwang, Ki-Song Kim 물리치료재활과학회 Physical Therapy Rehabilitation Science 5 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2018, 제 7권 제 1호 4 18-22 (5 pages)
Objective: This study aimed to investigate the effect of different-sized airways of the inspiratory muscle trainer (IMT) on maximal inspiratory pressure (MIP) and the rating of perceived exertion, as measured by the modified Borg scale (m-Borg). Design: Cross-sectional study. Methods: Twenty healthy subjects (10 men, 10 women) volunteered for the study. The spirometry was used to measure MIP. The trial order of the three spirometry conditions was chosen randomly. After measuring the MIP and... -
Effect of changes in head postures during use of laptops on muscle activity of the neck and trunk
Seul-gi Lee, Ye-seb Lee, Yi-jung Chung 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2017, 제 6권 제 1호 6 33-38 (6 pages)
Objective: This study tried to examine the muscle activity of the neck and trunk according to head posture changes during use of laptops. Design: Cross-sectional study. Methods: This study included nineteen young men and women. All subjects maintained each posture while practice typing on laptops for ten minutes with a 5-minute break between each posture. For the neutral head posture, the subjects practiced typing while pulling their chins down towards the Adam’s apple and were able to look at... -
The effect of applying a head-weight device on cervical angle and pain of neck muscles
Jin-Hong Kim, Jong-Gun Kim, Kwang-Sun Do, Jong-eun Yim 물리치료재활과학회 Physical Therapy Rehabilitation Science 5 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2016, 제 5권 제 2호 8 101-105 (5 pages)
Objective: The purpose of this study was to measure the change in pain threshold of levator scapular muscle, carniovertebral angle, and head position angle when applying a head-weight device on healthy adult. Design: Cross-sectional study. Methods: This study was conducted with 21 healthy adult male and female who voluntarily agreed to participate in this study after being informed of the purpose and method of this study. After measuring the cervical angle and pain threshold of levator scapular... -
Double filtration plasmapheresis in the treatment of hyperproteinemia in dogs affected by Leishmania infantum
Francesca Perondi, Claudio Brovida, Gianila Ceccherini, Grazia Guidi, Ilaria Lippi 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 3호 18 472-476 (5 pages)
Three dogs were evaluated for severe hyperproteinemia and hyperglobulinemia secondary to Leishmania infantum. Double filtration plasmapheresis (DFPP) was performed in two dogs at days 1, 2, and 6 after presentation. The third dog received DFPP at days 1 and 3 after presentation and eleven hemodialysis treatments. Significant reduction in serum total protein (p < 0.0001), alpha-1 (p = 0.023), alpha-2 (p = 0.018), gamma globulins (p = 0.0105), and a significant increase in albumin/globulin ratio... -
Evaluation of a fixed-dose combination of benazepril and pimobendan in dogs with congestive heart failure: a randomized non-inferiority clinical trial
Jonathan N. King, Atsushi Hirakawa, Junko Sonobe, Hiroshi Otaki, Nobuhiro Sakakibara, Wolfgang Seewald, Sophie Forster 대한수의학회 Journal of Veterinary Science 12 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 1호 15 117-128 (12 pages)
A fixed-dose combination tablet of benazepril and pimobendan (Fortekor Plus; Elanco Animal Health) was tested in dogs with congestive heart failure (CHF) caused by myxomatous mitral valve disease (MMVD) in a three-arm, masked, randomized, non-inferiority clinical trial in Japan. The test group (n = 34) received Fortekor Plus twice daily. Two control groups received registered formulations of benazepril (Fortekor; Elanco Animal Health) and pimobendan (Vetmedin; Boehringer Ingelheim Vetmedica)... -
Effects of aluminum on the reduction of neural stem cells, proliferating cells, and differentiating neuroblasts in the dentate gyrus of D-galactose-treated mice via increasing oxidative stress
Sung Min Nam, Jong Whi Kim, Dae Young Yoo, Woosuk Kim, Hyo Young Jung, Jung Hoon Choi, In Koo Hwang, Je Kyung Seong, Yeo Sung Yo 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 2호 1 127-136 (10 pages)
Aluminum (Al) accumulation increases with aging, and long-term exposure to Al is regarded as a risk factor for Alzheimer’s disease. In this study, we investigated the effects of Al and/or D-galactose on neural stem cells, proliferating cells, differentiating neuroblasts, and mature neurons in the hippocampal dentate gyrus. AlCl3 (40 mg/kg/day) was intraperitoneally administered to C57BL/6J mice for 4 weeks. In addition, vehicle (physiological saline) or D-galactose (100 mg/kg) was... -
Reduction of adult hippocampal neurogenesis is amplified by aluminum exposure in a model of type 2 diabetes
Sung Min Nam, Jong Whi Kim, Dae Young Yoo, Hyo Young Jung, Jung Hoon Choi, In Koo Hwang, Je Kyung Seong, Yeo Sung Yoon 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2016, 제 17권 제 1호 2 13-20 (8 pages)
In this study, we investigated the effects of chronic aluminum (Al) exposure for 10 weeks on cell proliferation and neuroblast differentiation in the hippocampus of type 2 diabetic rats. Six-week-old Zucker diabetic fatty (ZDF) and Zucker lean control (ZLC) rats were selected and randomly divided into Al- and non-Al-groups. Al was administered via drinking water for 10 weeks, after which the animals were sacrificed at 16 weeks of age. ZDF rats in both Al- and non-Al-groups showed increases in... -
Quantitative real-time polymerase chain reaction for detecting Mycoplasma hyosynoviae and Mycoplasma hyorhinis in pen-based oral, tonsillar, and nasal fluids
João Carlos Gomes Neto, Leslie Bower, Barbara Z. Erickson, Chong Wang, Matthew Raymond, Erin L. Strait 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 2호 9 195-201 (7 pages)
Mycoplasma (M.) hyorhinis and M. hyosynoviae are pathogens known to cause disease in pigs post-weaning. Due to their fastidious nature, there is increased need for culture-independent diagnostic platforms to detect these microorganisms. Therefore, this study was performed to develop and optimize quantitative real-time PCR (qPCR) assays to rapidly detect M. hyorhinis and M. hyosynoviae in pen-based oral fluids as well as nasal and tonsillar fluids as proxies for samples used in swine herd... -
Use of aglepristone for the treatment of P4 induced insulin resistance in dogs
Enrico Bigliardi*, Carla Bresciani, Daniela Callegari, Francesco Di Ianni, Giorgio Morini, Enrico Parmigiani, Ezio Bianchi 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 2호 13 267-271 (5 pages)
Insulin resistance (IR) in dogs is suspected when hyperglycemia is present despite administration of insulin doses greater than 1.0 to 1.5 UI/kg. IR is caused by increases in counter regulatory hormones concentrations (glucagon, glucocorticoids, catecholamines and growth hormone). This study was conducted to investigate the use of aglepristone (RU 46534), a P4 receptor antagonist, for the treatment of IR diabetes mellitus in bitches during the luteal phase. All animals were treated with porcine... -
Effects of one-time and two-time intra-articular injection of hyaluronic acid sodium salt after joint surgery in dogs
Korakot Nganvongpanit*, Burin Boonsri, Thatdanai Sripratak, Patsanan Markmee 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2013, 제 14권 제 2호 14 215-222 (8 pages)
4 weeks after injection for evaluation of chondroitin sulfate (CS-WF6) and hyaluronan (HA). The results revealed significantly (p < 0.05) improved clinical scores by the end of week 4 in G.1 and G.2 relative to G.3; however, there was no significant difference between G.1 and G.2. There was a significant decrease (p < 0.05) in serum CS-WF6 levels beginning at week 2 in G.1 and G.2. At weeks 3 and 4, serum HA in G.1 and G.2 differed from that in G.3 (p < 0.05). No significant difference (p >... -
Pulsed tissue Doppler imaging of the left ventricular septal mitral annulus in healthy dogs
Jihye Choi, Hyunwook Kim, Junghee Yoon* 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2013, 제 14권 제 1호 12 85-90 (6 pages)
This study evaluated pulsed TDI variables including the isovolumic time interval and duration of the major wave in a population of large healthy dogs. Longitudinal myocardial motion at the septal mitral annulus was evaluated with pulsed TDI in 45 healthy adult dogs. Maximal myocardial velocities, isovolumic time intervals, and duration of the myocardial waves were measured. The correlation between time intervals and velocity variables was also investigated. The mean maximal systolic velocity was... -
Cone beam computed tomography and intraoral radiography for diagnosis of dental abnormalities in dogs and cats
Marcello R. Roza*, Luiz Antonio F. Silva, Mauricio Barriviera, Alessandro L. Januário, Ana Cristina B. Bezerra, Maria Clori 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2011, 제 12권 제 4호 12 387-392 (6 pages)
The development of veterinary dentistry has substantially improved the ability to diagnose canine and feline dental abnormalities. Consequently, examinations previously performed only on humans are now available for small animals, thus improving the diagnostic quality. This has increased the need for technical qualification of veterinary professionals and increased technological investments. This study evaluated the use of cone beam computed tomography and intraoral radiography as complementary... -
Comparison between open and closed methods of herniorrhaphy in calves affected with umbilical hernia
Bibek Chandra Sutradhar*, Mohammad Farhad Hossain, Bhajan Chandra Das, Gonhyung Kim, Mohammad Alamgir Hossain 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2009, 제 10권 제 4호 11 343-347 (5 pages)
method-treated cases than in closed method-treated cases (5%). Hernia recurred in three calves treated with open herniorrhaphy within 2 weeks of the procedure, with swelling in situ and muscular weakness at the site of operation. Shorter operation time and excellent healing rate (80%) were found in calves treated with closed herniorrhaphy. These findings suggest that the closed herniorrhaphy is better than the commonly-used open method for the correction of reducible umbilical hernia in calves. -
Ultrasonographic evaluation of tracheal collapse in dogs
Kidong Eom, Kumjung Moon, Yunsang Seong, Taeho Oh, Sungjoon Yi, Keunwoo Lee, Kwangho Jang* 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 4호 10 401-406 (6 pages)
Tracheal ultrasonography was performed to measure the width of the tracheal ring shadow and to assess the clinical relevance of these measurements for identifying tracheal collapse. The first tracheal ring width (FTRW) and thoracic inlet tracheal ring width (TITRW) were measured on both expiration and inspiration. The mean of the FTRW width (129 dogs) was greater in expiration (10.97 ± 1.02 mm, p = 0.001) than that in inspiration (9.86 ± 1.03 mm). For 51 normal dogs, the mean of the... -
Bilateral Polydactyly in a foal
Bianca Carstanjen, Marie Abitbol, Christophe Desbois 대한수의학회 Journal of Veterinary Science 3 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 2호 17 201-203 (3 pages)
The following case report describes the diagnosis and surgery of bilateral polydactyly of unknown origin in a colt. A 7-month-old Berber colt was referred for cosmetic and curative excision of supernumerary digits. Radiographic examination revealed bilateral polydactyly and welldeveloped first carpal bones. Surgery consisted of an osteotomy of both second metacarpal bones combined with an amputation of the supernumerary digits. The follow-up at 18 months after surgery revealed a sound horse with... -
Successful introduction of modified dorsolumbar epidural anesthesia in a bovine referral center
Miho Hiraoka, Toshiharu Miyagawa, Hayato Kobayashi, Toshihiko Takahashi, Hiroaki Kishi, Hiroshi Kobayashi, Inhyung Lee 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 2호 13 181-184 (4 pages)
This study describes the successful use of modified dorsolumbar epidural anesthesia with a fixed volume of anesthetic in a bovine referral center. Among the 130 Holstein cattle scheduled for flank surgery, 90 cattle received a mixed anesthetic consisting of 1 ml of xylazine hydrochloride and 3 ml of lidocaine hydrochloride by modified dorsolumbar epidural anesthesia. Eighteen cattle with dehydration and/or lameness received a mixed anesthetic containing 0.5 ml of xylazine and 3 ml of lidocaine.... -
Organotypic slice culture of the hypothalamic paraventricular nucleus of rat
Eun Seong Cho, So Yeong Lee, Jae-Yong Park, Seong-Geun Hong, Pan Dong Ryu 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 1호 3 15-20 (6 pages)
Organotypic slice cultures have been developed as an alternative to acute brain slices because the neuronal viability and synaptic connectivity in these cultures can be preserved well for a prolonged period of time. This study evaluated a stationary organotypic slice culture developed for the hypothalamic paraventricular nucleus (PVN) of rat. The results showed that the slice cultures maintain the typical shape of the nucleus, the immunocytochemical signals for oxytocin, vasopressin, and... -
Effects of 5-HT4 selective receptor agonist, mosapride citrate on electrocardiogram in dogs
Ji Sang Chae , Jin Ok Ahn , Ye Rin Coh , Chong Woo Park , Hwa Young Youn 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 5 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2012, 제 52권 제 3호 3 163-167 (5 pages)
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토끼에서 출생 후 고환간질세포의 발생에 관한 연구
태현진, 박영재, 강형섭, 김남수 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 10 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2005, 제 45권 제 3호 2 325-334 (10 pages)
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Displacement and stress distribution of the maxillofacial complex during maxillary protraction using palatal plates
Jusuk Eom, Mohamed Bayome, Jae Hyun Park, Hee Jin Lim, Yoon-Ah Kook, Seong Ho Han 대한치과교정학회 The Korean Journal of Orthodontics 12 Pages
대한치과교정학회 The Korean Journal of Orthodontics 2018, 제 48권 제 5호 4 304-315 (12 pages)
Objective: The purpose of this study was to analyze initial displacement and stress distribution of the maxillofacial complex during dentoskeletal maxillary protraction with various appliance designs placed on the palatal region by using three-dimensional finite element analysis. Methods: Six models of maxillary protraction were developed: conventional facemask (Type A), facemask with dentoskeletal hybrid anchorage (Type B), facemask with a palatal plate (Type C), intraoral traction using a... -
CEPHALOMETRIC STUDY OF OBSTRUCTIVE SLEEP APNEA PATIENTS IN THE UPRIGHT AND SUPINE POSITIONS
Jong-Chul Kim, Alan A Lowe 대한치과교정학회 The Korean Journal of Orthodontics 10 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1995, 제 25권 제 6호 1 655-664 (10 pages)
Sixty male patients with polysomnographically documented OSA were included in this study. A pair of cephalograrns were obtained in the upright and supine positions. In the supine position, the ANB angle, lower facial height and the cross-sectional area of soft palate increased and there was a decrease in the vertical airway length and oropharynx cross-sectional area. Positional changes did not affect the cross-sectional area of tongue, but the cross-sectional area of the oropharynx decreased in... -
3급 부정교합 환자에서의 치료후 골격변화 양상에 관한 연구
정동화(Dong-Hwa Chung), 차경석(Kyung-Suk Cha) 대한치과교정학회 The Korean Journal of Orthodontics 13 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1996, 제 26권 제 3호 5 267-279 (13 pages)
교정치료는 치료 후의 분석이 이루어져야 그 성공여부를 평가받을 수 있다. 왜냐하면 교정치료는 환자자신의 고유한 균형을 변화시켜 또 다른 균형을 설정해가는 과정이기 때문이다. 그러나 1급이나 2급 부정교합에 비해 3급 부정교합 환자에 대한 연구는 미비하였다. 이 연구는 일반적인 교정치료시와 보정기간 중에는 어떠한 변화과정을 겪으며, 이들 중 재발 양상을 나타내는 요소에 대하여 치료 전의 골격형태와 치료기간 중 변화량과의 상관관계를 알아보고자 시행하였다. 초진시의 Hellman dental age가 ⅢB이상이며 1년... -
유성견 급속정중이개시 정중구개봉하부위의 조직학적 변화에 대한 연구
이두희(Doo-Hee Lee), 정규림(Kyu-Rhim Chung) 대한치과교정학회 The Korean Journal of Orthodontics 10 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1996, 제 26권 제 2호 3 153-162 (10 pages)
정중구개봉합의 급속확장은 상악골의 악궁의 폭을 증가시키고, 전방이동을 용이하게 하므로 전후방적인 악골의 부조화나 상악치열궁 협착 등을 치료하는데 널이 사용되고 있다. 이 연구는 정주구개봉합의 급속이개시 봉합부위에서 나타나는 골개조 판정 및 교원섬유의 변화를 관찰하고자 시행되었다. 생후 6-8개월된 유성견 4마리를 실험동물로 사용하여 인상을 채득한 후 주조된 급속정중이개장치에 Hyrax screw를 납착하여 장착시키고 1회에 90°씩, 1일 2회전시켜 10일간 지속하였다. X-ray상에서 봉합의 이개를 확인한 후... -
동화 각색을 이용한 주크박스 뮤지컬 프로그램 개발 - 초등학교 1,2학년 창의적 체험활동 시간을 중심으로 -
김민제, 공혜린 한국음악교육학회 음악교육연구 25 Pages
한국음악교육학회 음악교육연구 2021, 제 50권 제 4호 3 45-69 (25 pages)
이 연구는 동화 각색과 주크박스 뮤지컬 형식을 활용하여 초등학교 1-2학년을 대상으로 하는 음악교육 프로그램을 개발하는데 목적이 있다. 이를 위하여 준비, 개발, 시범 적용(파일럿)을 통한 수정 및 보완의 3단계 절차로 연구를 수행하였다. 최종 개발된 프로그램은 다음과 같은 특징 을 가진다. 첫째, 창의적 체험활동 교육과정과 즐거운 생활 교육과정의 주요 역량 중 하나인 심미 적 감성 역량, 창의적 사고 역량, 의사소통 역량 함양을 포함한다. 둘째, 즐거운 생활 교육과정의 음악 활동인 노래 부르기, 노랫말(가사) 바꾸기,... -
음악창작의 문화 비교를 위한 예비연구 - 한국과 미국을 중심으로 -
박은실, 강상미 한국음악교육학회 음악교육연구 22 Pages
한국음악교육학회 음악교육연구 2020, 제 49권 제 4호 3 53-74 (22 pages)
본 예비연구의 목적은 한국과 미국의 초등학교 고학년 학생들의 음악창작 결과를 분석하여 음악창작에 대한 문화를 비교하는 것이다. 32명의 한국학생들과 35명의 미국학생들을 대상으로 4주간 창작 지도를 하고 MuseScore2를 이용하여 8마디 가락을 창작하게 하였다. 합의적 평가기법(CAT)을 이용하여 평가한 결과, 두 나라 간 창의성에서 통계적으로 유의미한 차이가 없었다. 그러나 창의성에서 높은 점수와 낮은 점수를 받은 작품들을 추가적으로 분석한 결과, 창의성이 높은 그룹은 다양한 소리 선택, 발전과 대조, 구조화 등의... -
Camouflage Extraction Treatment of Unilateral Cleft Lip and Palate Patient: 4-year Follow-up
Woowon Jang, Jueon Song, Soonshin Hwang, Chooryung J. Chung, Kyung-Ho Kim 대한구순구개열학회 대한구순구개열학회지 7 Pages
대한구순구개열학회 대한구순구개열학회지 2019, 제 22권 1호 6 33-39 (7 pages)
Cleft lip and palate is one of the most common congenital abnormalities in the dentofacial region. Orthodontic treatment for adult patients with cleft lip and palate is difficult because of several factors such as dental anomalies, limitations in tooth movement around the cleft region, and retention. Here we report a case involving a 20-year-old woman with unilateral cleft lip and palate who successfully underwent camouflage orthodontic treatment for skeletal Class II malocclusion accompanied by... -
비주 결손의 범위에 따른 피판의 선택과 재건
송상현, 조혜민, 박진후, 정휘동, 정영수 대한구순구개열학회 대한구순구개열학회지 6 Pages
대한구순구개열학회 대한구순구개열학회지 2018, 제 21권 1호 5 23-28 (6 pages)
Congenital and acquired columella defect is rare. Columella is a small subunit of the nose, but determines the projection of nasal tip, defines the nasolabial angle, and is related to the structural relationship between alar rims and the nasal base. The showing of columella from various angles is also important for aesthetic point of view. Thus, reconstruction of columella defect is quite challengeable operation for surgeons. The recipient site should be harmonious with surrounding area, also... -
치조열환자에서 치조골 이식술의 예후
이수연, 명훈, 서병무, 황순정, 이종호, 김명진, 최진영 대한구순구개열학회 대한구순구개열학회지 8 Pages
대한구순구개열학회 대한구순구개열학회지 2006, 제 9권 2호 3 71-78 (8 pages)
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Molina distractor를 이용한 상/ 하악 동시 신장술 증례의 보고
백경원, 김근우, 최진영 대한구순구개열학회 대한구순구개열학회지 8 Pages
대한구순구개열학회 대한구순구개열학회지 2006, 제 9권 2호 1 55-62 (8 pages)
1980년 일리자로프가 하지에서의 골 신장술을 발표한 이래 수많은 외과 의사들이 임상연구와 발표를 거듭해 현재의 골 신장술을 이루었다. 악골에서 골 신장술의 적용은 1992년 8명의 악골 기형환아에게 하악지 신장술을 적용한 맥카시의 발표를 기점으로 시작되었다. 골 신장술의 장점은 부족한 골조직과 함께 주변 연조직을 신장시키는 것으로 복합적 조직 결손을 보이는 선천성 악골 기형 환자들에게 특히 유리하게 적용시킬 수 있다. 반안모 왜소증은 안면 반측의 상/하악골 및 악관절, 연조직의 저성장 및 결손을 보이는 비교적 흔한... -
편측성 구순구개열 환자에 있어 구순성형술과 동반한 서골피판법 치험례
박형욱, 송인석, 김유진, 김수호, 천강용, 서병무 대한구순구개열학회 대한구순구개열학회지 7 Pages
대한구순구개열학회 대한구순구개열학회지 2012, 제 15권 2호 2 61-67 (7 pages)
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Human umbilical cord blood mesenchymal stem cells engineered to overexpress growth factors accelerate outcomes in hair growth
Dong Ho Bak, Mi Ji Choi, Soon Re Kim, Byung Chul Lee, Jae Min Kim, Eun Su Jeon, Wonil Oh, Ee Seok Lim, Byung Cheol Park, Moo Joong Kim, Ju 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.5 9 555-566 (12 pages)
Human umbilical cord blood mesenchymal stem cells (hUCB-MSCs) are used in tissue repair and regeneration; however, the mechanisms involved are not well understood. We investigated the hair growth-promoting effects of hUCB-MSCs treatment to determine whether hUCB-MSCs enhance the promotion of hair growth. Furthermore, we attempted to identify the factors responsible for hair growth. The effects of hUCB-MSCs on hair growth were investigated in vivo, and hUCB-MSCs advanced anagen onset and hair... -
Dual control of the vestibulosympathetic reflex following hypotension in rats
SangEonPark, Yuan-ZheJin, ByungRimPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.6 13 675-686 (12 pages)
Orthostatic hypotension (OH) is associated with symptoms including headache, dizziness, and syncope. The incidence of OH increases with age. Attenuation of the vestibulosympathetic reflex (VSR) is also associated with an increased incidence of OH. In order to understand the pathophysiology of OH, we investigated the physiological characteristics of the VSR in the disorder. We applied sodium nitroprusside (SNP) to conscious rats with sinoaortic denervation in order to induce hypotension.... -
Effect of etoricoxib on experimental oxidative testicular ischemia–reperfusion damage in rats induced with torsion–detorsion
TurgutYapanoglu, FatihOzkaya, AliHaydarYilmaz, RenadMammadov, FerdaKeskinCimen, ErkanHirik, DurduAltuner 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.5 1 457-464 (8 pages)
Etoricoxib features antioxidant and anti-inflammatory properties concomitantly, suggesting that it may be beneficial in testicular ischemia reperfusion (I/R) damage. Our aim is to investigate the effects of etoricoxib on testicular I/R damage induced with torsion-detorsion (TD). The etoricoxib + torsion-detorsion (ETD) groups of animals were given etoricoxib in 50 and 100 mg/kg of body weight (ETD-50 and ETD-100), while the testes torsion-detorsion (TTD) and sham operation rat group (SOG)... -
Characteristics of K+ Outward Currents in the Cochlear Outer Hair Cells of Circling Mice within the First Postnatal Week
JiWoongAhn, ShinWookKang, SeungCheolAhn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.4 11 383-388 (6 pages)
K+ outward currents in the outer hair cells (OHCs) of circling mice (homozygous (cir/cir) mice), an animal model for human deafness (DFNB6 type), were investigated using a whole cell patch clamp technique. Littermate heterozygous (+/cir) mice of the same age (postnatal day (P) 0 −P6) were used as controls. Similar slow rising K+ currents were observed in both genotypes, but their biophysical and pharmacological properties were quite different. The values of Vhalf for activation were... -
Changes in c-Fos Expression in the Forced Swimming Test: Common and Distinct Modulation in Rat Brain by Desipramine and Citalopram
SunHyeChoi, SungChung, JinHeeCho, YunHaCho, JinWookKim, JeongMinKim, HeeJeongKim, HyunJuKim, KyungHoShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.4 10 321-329 (9 pages)
Rodents exposed to a 15-min pretest swim in the forced swimming test (FST) exhibit prolonged immobility in a subsequent 5-min test swim, and antidepressant treatment before the test swim reduces immobility. At present, neuronal circuits recruited by antidepressant before the test swim remain unclear, and also less is known about whether antidepressants with different mechanisms of action could influence neural circuits differentially. To reveal the neural circuits associated with antidepressant... -
Inhibitory Effects of Quercetin on Muscle-type of Nicotinic Acetylcholine Receptor-Mediated Ion Currents Expressed in Xenopus Oocytes
Byung-HwanLee, Tae-JoonShin, Sung-HeeHwang, Sun-HyeChoi, JiyeonKang, Hyeon-JoongKim, Chan-WooPark, Soo-HanLee, Seung-YeolNah 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.4 2 195-201 (7 pages)
The flavonoid quercetin is a low molecular weight compound generally found in apple, gingko, tomato, onion and other red-colored fruits and vegetables. Like other flavonoids, quercetin has diverse pharmacological actions. However, relatively little is known about the influence of quercetin effects in the regulation of ligand-gated ion channels. Previously, we reported that quercetin regulates subsets of nicotinic acetylcholine receptors such as Ձ3Ղ4, Ձ7 and Ձ9Ձ10.... -
Response of IKr and hERG Currents to the Antipsychotics Tiapride and Sulpiride
Su-HyunJo, So-YoungLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.5 9 305-310 (6 pages)
at the end of the voltage pulse, nor the amplitude of hERG tail currents, showed any concentration-dependent changes with either tiapride or sulpiride (3∼300</SUP>ՌM). However, our findings did show that tiapride increased the potential for half-maximal activation (V1/2) of HERG at 10∼300ՌM, whereas sulpiride increased the maximum conductance (Gmax) at 3, 10 and 100ՌM. In guinea pig ventricular myocytes, bath applications of 100 and 500ՌM tiapride at 36oC blocked... -
Effects of Isoflurane Anesthesia on Post-Anesthetic Sleep-Wake Architectures in Rats
Hwan-SooJang, Ji-YoungJung, Kwang-HoJang, Maan-GeeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.5 7 291-297 (7 pages)
The sleep homeostatic response significantly affects the state of anesthesia. In addition, sleep recovery may occur during anesthesia, either via a natural sleep-like process to occur or via a direct restorative effect. Little is known about the effects of isoflurane anesthesia on sleep homeostasis. We investigated whether 1) isoflurane anesthesia could provide a sleep-like process, and 2) the depth of anesthesia could differently affect the post-anesthesia sleep response. Nine rats were treated... -
A Carbohydrate Fraction, AIP1, from Artemisia Iwayomogi Reduces the Action Potential Duration by Activation of Rapidly Activating Delayed Rectifier K+ Channels in Rabbit Ventricular Myocytes
WonSunPark, YounKyoungSon, EunAKo, SeongWooChoi, NariKim, Tae-HoonChoi, HyunJooYoun, Su-HyunJo, DaHyeHong, JinHan 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.3 1 119-125 (7 pages)
We investigated the effects of a hot-water extract of Artemisia iwayomogi, a plant belonging to family Compositae, on cardiac ventricular delayed rectifier K+ current (IK) using the patch clamp technique. The carbohydrate fraction AIP1 dose-dependently increased the heart rate with an apparent EC50 value of 56.1±5.5Ռg/ml. Application of AIP1 reduced the action potential duration (APD) in concentration-dependent fashion by activating IK without significantly altering the resting membrane... -
Direct Block of Cloned K+ Channels, Kv1.5 and Kv1.3, by Cyclosporin A, Independent of Calcineurin Inhibition
BokHeeChoi, SangJuneHahn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.6 7 353-362 (10 pages)
The interaction of cyclosporine A (CsA), an immunosuppressant, with rat brain Kv1.5 (Kv1.5) channels, which were stably expressed in Chinese hamster ovary cells, was investigated using the whole-cell patch-clamp technique. CsA reversibly blocked Kv1.5 currents at 50 mV in a reversible concentration- dependent manner with an apparent IC50 of 1.0μM. Other calcineurin inhibitors (cypermethrin, autoinhibitory peptide) had no effect on Kv1.5 and did not prevent the inhibitory effect of CsA.... -
Effects of Local Anesthetics on Rotational Mobility of n-(9-Anthroyloxy)stearic Acid in Neuronal Membranes
Hye-OckJang, ChangLee, Min-GakChoi, Sang-HunShin, In-KyoChung, IlYun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.3 1 119-124 (6 pages)
To elucidate the molecular mechanism of pharmacological action of local anesthetics, we studied membrane actions of tetracaine, bupivacaine, lidocaine, prilocaine and procaine. Fluorescence polarization of n-(9-anthroyloxy)stearic acid (n-AS) was used to examine the effects of these local anesthetics on differential rotational mobility of different positions of the number of synaptosomal plasma membrane vesicle (SPMV) phospholipid carbon atoms. The four membrane components differed with respect... -
Involvement of NAD(P)H Oxidase in a Potential Link between Diabetes and Vascular Smooth Muscle Cell Proliferation
HyeYoungJeong, MiRanYun, ChiDaeKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.2 9 103-109 (7 pages)
The cellular mechanisms that contribute to the acceleration of atherosclerosis in diabetes are poorly understood. Therefore, the potential mechanisms involved in the diabetes-dependent increase in vascular smooth muscle cell (VSMC) proliferation was investigated. Using primary culture of VSMC from streptozotocin-induced diabetic rat aorta, cell proliferation assay showed two-fold increase in cell number accompanied with enhanced superoxide generation compared to normal VSMC, 2 days after... -
Altered Secretory Pattern of Pancreatic Enzymes and Gastrointestinal Hormones in Streptozotocin-induced Diabetic Rats
Myung-JunKim, GyeongRyulRyu, Sae-YoungYi, DoSikMin, Duck-JooRhie, ShinHeeYoon, SangJuneHahn, Myung-SukKim, Yang-HyeokJo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2002, Vol.6 No.6 6 311-317 (7 pages)
This study was performed to investigate the pancreatic exocrine dysfunction in streptozotocin- induced diabetic rats. Changes in pancreatic enzymes secretion and in pancreatic enzymes content were observed. The output and the tissue content of amylase were significantly reduced in diabetic rats, while the output and the content of lipase were increased. Plasma secretin and cholecystokinin (CCK) concentrations of diabetic rats were significantly increased compared to those of normal rats. The...


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