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임상 빅데이터를 이용한 영적간호진단 적용 현황 분석
김형순, 박현숙, 정현숙, 김미경, 박은영, 김동연 한국근거기반간호학회 근거와 간호 12 Pages
한국근거기반간호학회 근거와 간호 2021, 제 9권 제 1호 2 10-21 (12 pages)
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The effects of an additional weight aquatic exercise program on balance and lower extremity strength in persons with stroke
Jae-ho Park, Yi-jung Chung 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2018, 제 7권 제 1호 2 6-12 (7 pages)
Objective: The purpose of this study was to investigate the effects of an additional weight aquatic exercise program on the balance and lower extremity strength on aquatic environment in persons with stroke. Design: Randomized controlled trial. Methods: All subjects were randomly divided into three groups where thirteen subjects were in the additional weight aquatic exercise group, twelve subjects in the aquatic exercise group, and fifteen subjects in the control group. Subjects received a... -
나쁜 소식 전하기와 관련된 개인적 특성이 학생들의 의사소통기술에 영향을 미치는가?
임선주(Sun Ju Im), 윤소정(So Jung Yune), 이상엽(Sang Yeoup Lee), 정해진(Hae Jin Jeong), 강신영(Shin Young Kang), 감비성(Bee Sung Kam), 윤형곤(Hyung Gon Yoo 한국의학교육학회 Korean Journal of Medical Education 10 Pages
한국의학교육학회 Korean Journal of Medical Education 2008, 제 20권 제 3호 7 231-240 (10 pages)
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Lateral flow immunocharomtographic assay for earlyand rapid detection of antibody to porcine reproductive and respiratorysyndrome virus in porcine plasma
In Ohk Ouh, Kwang Myun Cheong, Sang Oh Lee, Chun Hoi Kim, Eun Sung Jeon, Hye Young Lee, Ji Eun Yu, Jae Young Song, In Soo Cho, Sang Ho C 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 256 475-476 (2 pages)
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Evaluation of potassium clavulanate as supplement to selective medium and the effect of incubation conditions for detecting Campylobacter
Bai Wei, Se Yeoun Cha, Ke Shang, Jeong Woo Kang, Hae Chul Park, Kwang Jick Lee, Hyung Kwan Jang 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 218 312-313 (2 pages)
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Antimicrobial susceptibility of Campylobacter isolates from breeder and broiler flocks in Korea
Bai Wei, Se Yeoun Cha, Min Kang, Jun Feng Zhang, Yong Tack Hong, Jeong Woo Kang, Hae Chul Park, Kwang Jick Lee, Hyung Kwan Jang 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 217 311-312 (2 pages)
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Rapid visual detection of Mycobacterium avium subsp. paratuberculosis by recombinase polymerase amplification combined with a lateral flow dipstick
Guimin Zhao, Hongmei Wang, Peili Hou, Chengqiang He, Hongbin He 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 2호 10 242-250 (9 pages)
Paratuberculosis (Johne’s disease) is a chronic debilitating disease of domestic and wild ruminants. However, widespread point-of-care testing is infrequent due to the lack of a robust method. The isothermal recombinase polymerase amplification (RPA) technique has applied for rapid diagnosis. Herein, RPA combined with a lateral flow dipstick (LFD) assay was developed to estimate DNA from Mycobacterium avium subsp. paratuberculosis. First, analytical specificity and sensitivity of the RPA-nfo... -
Prepubertal growth and single nucleotide polymorphism analysis of the growth hormone gene of low birth weight Holstein calves
Younghye Ro, Woojae Choi, Hoyung Kim, Hojin Jang, Hoseon Lee, Yoonseok Lee, Danil Kim 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 1호 20 157-160 (4 pages)
Holstein calves weighing less than 20 kg at birth have been noted in Korea. Due to insufficient information, we raised small calves with age-matched normal birth weight Holstein calves and determined body weights before puberty. In addition, 3 single nucleotide polymorphisms (SNPs) of the growth hormone (GH) gene were analyzed. Up to 10 months of age, low birth weight calves were smaller than normal weight calves. In exon 5 of the GH gene, SNP genotype variation was detected in some small... -
Development of an immunochromatographic strip for detection of antibodies against porcine reproductive and respiratory syndrome virus
Huawei Li, Jifei Yang, Dengke Bao, Jie Hou, Yubao Zhi, Yanyan Yang, Pengchao Ji, Enmin Zhou, Songlin Qiao, Gaiping Zhang 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 3호 7 307-316 (10 pages)
A simple and rapid immunochromatographic test strip incorporating a colloidal gold-labeled recombinant Nsp7 antigen probe was successfully developed for the detection of anti-porcine reproductive and respiratory syndrome virus (PRRSV) antibodies in swine. Recombinant Nsp7 protein of PRRSV labeled with colloidal gold was dispensed on a conjugate pad for use as the detector. Staphylococcal protein A and purified porcine anti-Nsp7 antibodies were blotted on a nitrocellulose membrane to form test... -
Phenotypic and genotypic antimicrobial resistance and virulence genes of Salmonella enterica isolated from pet dogs and cats
Songsak Srisanga, Sunpetch Angkititrakul, Patcharee Sringam, Phuong T. Le Ho, An T. T. Vo, Rungtip Chuanchuen 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 3호 3 273-281 (9 pages)
Salmonella enterica isolates (n = 122), including 32 serotypes from 113 dogs and 9 cats, were obtained from household dogs (n = 250) and cats (n = 50) during 2012?2015. The isolates were characterized by serotyping, antimicrobial resistance phenotyping and genotyping, and virulence gene screening. Serovars Weltevreden (15.6%) and Typhimurium (13.9%) were the most common. The majority (43%) of the isolates were multidrug resistant. The dog isolates (12.3%) harbored class 1 integrons, of which the... -
Enhancing effects of serum-rich and cytokine-supplemented culture conditions on developing blastocysts and deriving porcine parthenogenetic embryonic stem cells
Soo-Kyung Jung, Hyun-Jung Kim, Chan-Lan Kim, Joo-Hyeong Lee, Jin-Young You, Eun-Song Lee, Jeong-Mook Lim, Seon Jong Yun, Jae-You 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 4호 9 519-528 (10 pages)
The present study was conducted to develop an effective method for establishment of porcine parthenogenetic embryonic stem cells (ppESCs) from parthenogenetically activated oocyte-derived blastocysts. The addition of 10% fetal bovine serum (FBS) to the medium on the 3rd day of oocyte culturing improved the development of blastocysts, attachment of inner cell masses (ICMs) onto feeder cells, and formation of primitive ppESC colonies. ICM attachment was further enhanced by basic fibroblast growth... -
Betulinic acid prevents alcohol-induced liver damage by improving the antioxidant system in mice
Jine Yi*, Wei Xia, Jianping Wu, Liyun Yuan, Jing Wu, Di Tu, Jun Fang, Zhuliang Tan* 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 1호 16 141-148 (8 pages)
Betulinic acid (BA), a pentacyclic lupane-type triterpene, has a wide range of bioactivities. The main objective of this work was to evaluate the hepatoprotective activity of BA and the potential mechanism underlying the ability of this compound to prevent liver damage induced by alcohol in vivo. Mice were given oral doses of BA (0.25, 0.5, and 1.0 mg/kg) daily for 14 days, and induced liver injury by feeding 50% alcohol orally at the dosage of 10 ml/kg after 1 h last administration of BA. BA... -
Evaluation of the estrogenic effects of dietary perinatal Trifolium pratense
Emrah Yatkin, Suzan Daglioglu 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2011, 제 12권 제 2호 3 121-126 (6 pages)
This study was designed to investigate the potential estrogenic effects of perinatal dietary phytoestrogens on the rat uterus. Pregnant rats were divided to three groups provided the following diets: (1) rat chow, (2) rat chow with 7.5% Trifolium (T.) pratense, or (3) rat chow supplemented with 17β-estradiol (0.5 mg/kg). The dams in each group were kept on the same diet during pregnancy and lactation. Female offspring were euthanized on day 21 at which time body and organ weights were recorded... -
Detection of Helicobacter spp. in gastric, fecal and saliva samples from swine affected by gastric ulceration
Patrizia Casagrande Proietti*, Annalisa Bietta, Chiara Brachelente, Elvio Lepri, Irit Davidson, Maria Pia Franciosini 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2010, 제 11권 제 3호 7 221-225 (5 pages)
The aim of this study was to evaluate the presence of Helicobacter (H.) spp. in swine affected by gastric ulceration. Stomachs from 400 regularly slaughtered swine were subjected to gross pathological examination to evaluate the presence of gastric ulcers. Sixty-five samples collected from ulcerated pars esophagea and 15 samples from non-ulcerated pyloric portions were submitted to histopathological and molecular analyses, to detect Helicobacter spp., H. suis and H. pylori by PCR. Feces and... -
Evaluation of PCR inhibitory effect of enrichment broths and comparison of DNA extraction methods for detection of Salmonella Enteritidis using real-time PCR assay
Ji-Yeon Hyeon, In-Gyun Hwang, Hyo-Sun Kwak, Chankyu Park, In-Soo Choi, Kun-Ho Seo 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2010, 제 11권 제 2호 8 143-149 (7 pages)
The best enrichment broth and DNA extraction scheme was determined for rapid and sensitive detection of Salmonella Enteritidis in steamed pork using real-time PCR. The inhibitory effect of commonly used Salmonella enrichment broths, Rappaport-Vassiliadis (RV) and Muller-Kauffmann tetrathionate with novobiocin (MKTTn), on real-time PCR was confirmed. The inhibition of PCR was statistically significant (p < 0.05) in RV and MKTTn, as compared with buffered peptone water (BPW) or phosphate-buffered... -
The combination of deoxynivalenol and zearalenone at permitted feed concentrations causes serious physiological effects in young pigs
Feng Chen, Yulin Ma, Chunyi Xue, Jingyun Ma, Qingmei Xie, Genhu Wang, Yingzuo Bi, Yongchang Cao, * 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 1호 6 39-44 (6 pages)
This study was to investigate the effects of the combination of deoxynivalenol (DON) and zearalenone (ZON) on pigs. Twenty-four weaning piglets were divided into a control group fed a diet free of mycotoxins and a toxin group fed a diet containing 1 mg/kg DON and 250 Ռg/kg ZON. The results showed that supplementation of DON and ZON in diets had extensive effects on pigs. More specifically, DON and ZON caused levels of total protein, albumin, and globulin in sera to decrease (p < 0.05) by... -
In vitro susceptibilities of Leptospira spp. and Borrelia burgdorferi isolates to amoxicillin, tilmicosin, and enrofloxacin
Doo Kim, Dorsey Kordick, Thomas Divers, Yung-Fu Chang 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 4호 9 355-359 (5 pages)
Antimicrobial susceptibility testing was conducted with 6 different spirochetal strains (4 strains of Leptospira spp. and 2 strains of Borrelia burgdorferi) against 3 antimicrobial agents, commonly used in equine and bovine practice. The ranges of MIC and MBC of amoxicillin against Leptospira spp. were 0.05-6.25 μg/ml and 6.25-25.0 μg/ml, respectively. And the ranges of minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) of amoxicillin against B. burgdorferi... -
General pharmacological profiles of bee venom and its water soluble fractions in rodent models
Hyun-Woo Kim, Young-Bae Kwon, Tae-Won Ham, Dae-Hyun Roh, Seo-Yeon Yoon, Seuk-Yun Kang, Il-Suk Yang, Ho-Jae Han, Hye-Jung Lee, Al 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2004, 제 5권 제 4호 5 309-318 (10 pages)
Recently, the antinociceptive and anti-inflammatory efficacy of bee venom (BV, Apis mellifera) has been confirmed in rodent models of inflammation and arthritis. Interestingly, the antinociceptive and anti-inflammatory effect of whole BV can be reproduced by two water-soluble fractions of BV (>20 kDa:BVAF1 and<10 kDa: BVAF3). Based on these scientific findings, BV and its effective water-soluble fractions have been proposed as potential anti-inflammatory and antinociceptive pharmaceuticals.... -
Immunostimulatory effects of anionic alkali mineral complex solution Barodon in porcine lymphocytes
Byung Woo Yoo, Soo Il Choi, So Hyun Kim, Soo Jin Yang, Hye Cheong Koo, Sang Hoon Seo, Bong Kyun Park, Han Sang Yoo, Yong Ho Park 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2001, 제 2권 제 1호 3 15-24 (10 pages)
The anionic alkali mineral complex solution, Barodon (Barodon-S.F. Corp., Korea), was evaluated for its effectiveness as a nonspecific immunostimulator in pigs. The effects of Barodon were determined by analysis of feed efficiency, growth rate, and phenotype of leukocyte subpopulations using monoclonal antibodies specific to porcine leukocyte differentiation antigens and flow cytometry (FC). The study was focused to investigate the change in proportion of the CD4+CD8+ double positive T... -
Tricuspid valve dysplasia complicated with pulmonic regurgitation in a Cocker Spaniel dog
So Jeong Nam , Ran Choi , In Chul Park , Chang Baig Hyun , 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 7 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2008, 제 48권 제 4호 13 481-487 (7 pages)
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ARTISTS IN SCHOOLS: A CASE STUDY OF THE ARTS-IN-EDUCATION PROJECT
Jane CHEUNG 한국음악교육공학회 음악교육공학 11 Pages
한국음악교육공학회 음악교육공학 2004, 제 4호 8 135-145 (11 pages)
최근 예술교육개혁의 목표는 학교 단위의 예술 교과과정의 발달을 위해서 학교에 더 많은 자치권을 허용하고, 예술에서의 우선권을 수행하기 위해 학생들에게 더욱 더 새로운 형태의 공간을 제공하는 등의 실제 현장에서의 장점을 만드는 것이다. 이 연구에서는 홍콩의 2개의 고등학교에서 시도된 학교 교육과정, 학생의 학습과 예술가와의 협력에 관한 “교육에서의 예술” 프로젝트의 효과를 조사하였다. 음악적 생산물에 대해 공식적인 시간과 비공식적인 시간 동안 학교교사와 협력적으로 일한 예술가에 대한 사례연구 결과는 특별한... -
그래미 음악교육가상이 미국 음악교육에 미친 영향
한국음악교육학회 음악교육연구 2020, 제 49권 제 4호 10 231-250 (20 pages)
본 연구는 미국 ‘그래미 음악교육가상’이 미국 음악교육의 사회적 인식 변화와 발전에 미친 영향을 탐구 하는데 목적이 있다. 미국 교육가상의 특징을 살펴보기 위해 미국 주요 교육가상의 종류, 선발기준, 선발방법 등을 조사하고, 그래미 음악교육가상의 제정 과정, 선정 참여 주체, 선정 방법 등을 조사하였다. 연구결과 미국 그래미 음악교육가상은 미국 그래미상의 사회적, 문화적, 경제적 영향력에 힘입어 미국 사회에 음악교육의 중요성과 음악교사의 가치를 널리 알리는데 주요한 역할을 했으며, 미국 음악 교육가들과 함께... -
최근 독일 음악과 교육과정의 구조적 특징
한국음악교육학회 음악교육연구 2019, 제 48권 제 4호 11 223-251 (29 pages)
본 연구는 독일의 최근 음악과 교육과정에 나타난 구조적 다양성을 들춰내고 그 함의를 밝혀내고자 한다. 독일 각 주에서 사용하는 모든 음악과 교육과정을 분석해 본 결과, 그 체제는 교사에게 학습 내용을 실제적으로 안내하는 방식을 취하고 있었다. 하지만 교육과정의 명칭과 내용 구조 및 역량 안내가 주에 따라 다양했다. 그럼에도 불구하고 역량 중심으로 음악과 교육과정을 설계하는 것이 기본 추세인 것으로 나타났다. 주에 따라 음악과 교육과정의 개정 시기가 다름에도 전반적으로 역량 중심의 체제를 사용하면서 학습 영역을... -
Fuller와 Bown의 교사염려모델에 기초한 예비 초등교사의 음악교수에 대한 염려 조사
최미영(Mi Young Choi) 한국음악교육학회 음악교육연구 18 Pages
한국음악교육학회 음악교육연구 2016, 제 45권 제 2호 11 275-292 (18 pages)
본 연구의 목적은 Fuller와 Bown의 교사염려모델을 사용하여 예비 초등교사의 음악교수에 대한 염려를 알아보는데 있다. 연구대상은 교육대학교 음악교육 심화전공 4학년 예비교사 15명이다. 연구 자료로는 동료학생 대상의 모의 음악수업과 교육실습 음악수업에서 각각 사용된 교수학습 지도안, 동료교수 음악수업과 교육실습 음악수업에서 촬영한 수업 DVD, 그리고 각각의 수업에서 수업을 마친 후 예비교사가 기록한 자기 평가지 및 연구자와의 비구조화된 인터뷰가 사용되었다. 예비 초등교사의 자기 평가지와 전사한 인터뷰의 내용은... -
Antipruritic effect of curcumin on histamine-induced itching in mice
Han Kyu Lee, Seok Bum Park, Su-youne Chang, Sung Jun Jung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.5 8 547-554 (8 pages)
Itching is a common clinical symptom of skin disease that significantly affects a patient’s quality of life. Transient receptor potential vanilloid 1 (TRPV1) receptors of keratinocytes and peripheral nerve fibers in skin are involved in the regulation of itching as well as pain. In this study, we investigated whether curcumin, which acts on TRPV1 receptors, affects histamine-induced itching in mice, using behavioral tests and electrophysiological approaches. We found that histamine-induced... -
Neuroprotective effect of lithium after pilocarpine-induced status epilepticus in mice
NamgueHong, Yun-SikChoi, SeongYunKim, HeeJungKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.1 15 125-131 (7 pages)
Status epilepticus is the most common serious neurological condition triggered by abnormal electrical activity, leading to severe and widespread cell loss in the brain. Lithium has been one of the main drugs used for the treatment of bipolar disorder for decades, and its anticonvulsant and neuroprotective properties have been described in several neurological disease models. However, the therapeutic mechanisms underlying lithium’s actions remain poorly understood. The muscarinic receptor... -
Dehydroevodiamine·HCl enhances cognitive function in memory-impaired rat models
KiYoungShin, KaYoungKim, Yoo-HunSuh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.1 7 55-64 (10 pages)
Progressive memory impairment such as that associated with depression, stroke, and Alzheimer’s disease (AD) can interfere with daily life. In particular, AD, which is a progressive neurodegenerative disorder, prominently features a memory and learning impairment that is related to changes in acetylcholine and abnormal β-amyloid (Aβ) deposition in the brain. In the present study, we investigated the effects of dehydroevodiamine·HCl (DHED) on cognitive improvement and the related mechanism in... -
Dexmedetomidine Modulates Histamine-induced Ca2+ Signaling and Pro-inflammatory Cytokine Expression
DongkiYang, JeongHeeHong 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.5 3 413-420 (8 pages)
Dexmedetomidine is a sedative and analgesic agent that exerts its effects by selectively agonizing α2 adrenoceptor. Histamine is a pathophysiological amine that activates G protein-coupled receptors, to induce Ca2+ release and subsequent mediate or progress inflammation. Dexmedetomidine has been reported to exert inhibitory effect on inflammation both in vitro and in vivo studies. However, it is unclear that dexmedetomidine modulates histamine-induced signaling and pro-inflammatory cytokine... -
Association of Angiotensin Converting Enzyme I/D and α-actinin-3 R577X Genotypes with Growth Factors and Physical Fitness in Korean Children
KijinKim, NayoungAhn, WookwangCheun, ChangbaeHong, JayoungByun, YoungsikJoo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.2 8 131-139 (9 pages)
This study analyzed the differences in aerobic and anaerobic exercise ability and growth-related indicators, depending on the polymorphism of the ACE and the ACTN3 genes, to understand the genetic influence of exercise ability in the growth process of children. The subjects of the study consisted of elementary school students (n=856, age 10.32±0.07 yr). The anthropometric parameters, physical fitness and growth factors were compared among groups of the ACE I/D or the ACTN3 R577X polymorphisms.... -
Scant Extracellular NAD Cleaving Activity of Human Neutrophils is Down-Regulated by fMLP via FPRL1
Md.AshrafulHasan, Md.TipuSultan, Won-GyunAhn, Yeon-JaKim, Ji-HyeJang, Chang-WonHong, Dong-KeunSong 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.6 8 497-502 (6 pages)
have scant extracellular ethe-no-NAD cleaving activity, which is much less than that of mouse bone marrow neutrophils, mouse peripheral neutrophils, human monocytes and lymphocytes. With high performance liquid chroma-tography (HPLC), we have identified that ADP-ribose (ADPR) is the major extracellular metabolite of NAD degradation by intact human neutrophils. The scant extracellular etheno-NAD cleaving activity is decreased further by N-formyl-methionine-leucine-phenylalanine (fMLP), a... -
Cardiac Damage Biomarkers Following a Triathlon in Elite and Non-elite Triathletes
Chan-HoPark, Kwi-BaekKim, JinHan, Jin-GooJi, Yi-SubKwak 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.5 10 419-423 (5 pages)
in elite and non-elite athlete groups. Fifteen healthy men participated in the study. Based on performance, they were divided into elite athlete group (EG: n=7) and non-elite athlete group (NEG: n=8). Participants’ blood samples were obtained during four periods: before, immediately, 2 hours and 7 days after finishing the race. creatine kinase (CK), creatine kinase-myoglobin (CK-MB), myoglobin, and lactate dehydrogenase (LDH) were significantly increased in both groups immediately after, and... -
Push-in Head Restraining Apparatus for Intracranial Self Stimulation Tasks in Rats
MootaekRoh, Il-SungJang, Maan-GeeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.2 3 103-108 (6 pages)
Head restraining is an experimental technique that firmly secures the animal’s head to a fixation apparatus for the precise control and sensing of behaviors. However, procedural and surgical difficulties and limitations have been obstructing the use of the technique in neurophysiological and behavioral experiments. Here, we propose a novel design of the head-restraining apparatus which is easy to develop and convenient for practical use. Head restraining procedure can be completed by sliding... -
Neuronal Responses in the Globus Pallidus during Subthalamic Nucleus Electrical Stimulation in Normal and Parkinson's Disease Model Rats
SangBaekRyu, EunKyungBae, JinhyungKim, , YongSupHwang, , ChangkyunIm, JinWooChang, , Hyung-CheulShin, KyungHwanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.4 7 299-306 (8 pages)
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) has been widely used as a treatment for the movement disturbances caused by Parkinson's disease (PD). Despite successful application of DBS, its mechanism of therapeutic effect is not clearly understood. Because PD results from the degeneration of dopamine neurons that affect the basal ganglia (BG) network, investigation of neuronal responses of BG neurons during STN DBS can provide informative insights for the understanding of the... -
Differential Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on Motor Behavior and Dopamine Levels at Brain Regions in Three Different Mouse Strains
Keun-SungLee, Jin-KooLee, Hyung-GunKim, HakRimKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.1 13 89-97 (9 pages)
Developing an animal model for a specific disease is very important in the understanding of the underlying mechanism of the disease and allows testing of newly developed new drugs before human application. However, which of the plethora of experimental animal species to use in model development can be perplexing. Administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is a very well known method to induce the symptoms of Parkinson's disease in mice. But, there is very limited...


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