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Neuroprotective effect of Sigesbeckia pubescens extract onglutamate-induced oxidative stress in HT22 cells via downregulation of MAPKs and caspase pathway
Rashedunnabi Aka, In shik Kim, Dong choon Ahn, Hyun Jin Tae, Gi Beum Kim, Byung Yong Park 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 294 353-353 (1 pages)
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Cytoprotective Constituents of Alpinia katsumadai Seeds Against Glutamate-Induced Oxidative Injury in HT22 Cells
Jeong. Gil-Saeng, Li. Bin, Lee. Dong-Sung, Byun. Erisa, Kang. Dae-Gill, Lee. Ho-Sub, Kim. Youn-Chul 한국생약학회 Natural product sciences 4 Pages
한국생약학회 Natural product sciences 2007, Vol.13 No.3 268-271 (4 pages)
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Cytoprotective Activity of Belamcanda chinensis Rhizome Against Glutamate-Induced Oxidative Injury in HT22 Cells
Jeong. Gil-Saeng, An. Ren-Bo, Oh. Seung-Hwan, Kang. Dae-Gill, Lee. Ho-Sub, Kim. Youn-Chul 한국생약학회 Natural product sciences 4 Pages
한국생약학회 Natural product sciences 2007, Vol.13 No.2 101-104 (4 pages)
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Triptolide Inhibits the Proliferation of Immortalized HT22 Hippocampal Cells Via Persistent Activation of Extracellular Signal-Regulated Kinase-1/2 by Down-Regulating Mitogen-Activated Protein Kinase Phosphatase-1 Expression
Koo. Hee-Sang, Kang. Sung-Don, Lee. Ju-Hwan, Kim. Nam-Ho, Chung. Hun-Taeg, Pae. Hyun-Ock 대한신경외과학회 Journal of Korean neurosurgical society 8 Pages
대한신경외과학회 Journal of Korean neurosurgical society 2009, Vol.46 No.4 389-396 (8 pages)
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Water Extract of Samultang Reduces Apoptotic Cell Death by H2O2-Induced Oxidative Injury in SK-N-MC Cells
GyoungWanLee, MinSunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.3 1 139-145 (7 pages)
Chinese herb, on apoptotic cell death by H2O2-induced oxidative stress in SK-N-MC cells. A nuclear fragmentation was observed via fluorescence imaging 12 h after exposure to 30</SUB>ՌM H2O2 and DNA laddering was detected via agarose electrophoresis gel. In addition, increases in sub-G1 phase and cleavage of the PARP protein were observed. However, treatment with SMT for 2 h prior to H2O2 exposure significantly reduced apoptotic cell death induced by incubation with 30ՌM H2O2 in... -
글루타메이트로 유발한 HT22세포 독성에 대한 백두산 식물 추출물의 보호 효과
리빈, 정길생, 안인파, 이동성, 변에리사, 윤권하, 김윤철, Li. Bin, Jeong. Gil-Saeng, An. Ren-Bo, Lee. Dong-Sung, Byun. Erisa, Yoon. Kwon-Ha, Kim. Youn-Chul 한국생약학회 생약학회지 5 Pages
한국생약학회 생약학회지 2008, Vol.39 No.3 213-217 (5 pages)
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물푸레나무 수피의 생쥐 해마 유래 HT22 세포 보호와 항산화 활성 물질
정길생, 윤권하, 김현철, 오승환, 김명중, 강대길, 이호섭, 김윤철, Jeong. Gil-Saeng, Yoon. Kwon-Ha, Kim. Hyun-Chul, Oh. Seung-Hwan, Kim. Myong-Jung, Kang. Dae-Gill, Lee. 한국생약학회 생약학회지 4 Pages
한국생약학회 생약학회지 2007, Vol.38 No.3 287-290 (4 pages)
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HT22 세포에서 Curcumin 유도체가 Heme Oxygenase-1 발현에 미치는 효과
정용관, 이윤정, 천현자, 류일환, 지연주, 채권우, 김영숙, 손지우, 강현규, 이성희, 안인파, 정헌택, 배현옥, Cheong. Yong-Kwan, Lee. Yun-Jung, Chun. Hyun-Ja, Ryu. Il-Hwan, Jee. Yeon-Ju, Chae 대한약학회 약학회지 5 Pages
대한약학회 약학회지 2011, Vol.55 No.4 319-323 (5 pages)
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Isolation and characterization of the Citrobacter freundii phage EF1 from earthworm (Eisenia fetida)
Jun Heon Yeo, Jung Seok Lee, Se Pyeong Im, Jassy Mary Lazarte, Si Won Kim, Jae Wook Jung, Hong Jae Shin, Jung Yeol Bae, Ae Rin Lee, Jae s 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 293 352-353 (2 pages)
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Neuroprotective effect of caffeic acid phenethyl ester in 3-nitropropionic acid-induced striatal neurotoxicity
JiaBak, HeeJungKim, SeongYunKim, Yun-SikChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.3 7 279-286 (8 pages)
Caffeic acid phenethyl ester (CAPE), derived from honeybee hives, is a bioactive compound with strong antioxidant activity. This study was designed to test the neuroprotective effect of CAPE in 3-nitropropionic acid (3NP)-induced striatal neurotoxicity, a chemical model of Huntington’s disease (HD). Initially, to test CAPE’s antioxidant activity, a 2,2’-azino-bis-3-ethylbenzthiazoline-6-sulfonic acid (ABTS) antioxidant assay was employed, and CAPE showed a strong direct radicalscavenging eff... -
Carnosic acid protects against acetaminophen-induced hepatotoxicity by potentiating Nrf2-mediated antioxidant capacity in mice
QiGuo, ZhiyangShen, HongxiaYu, GaofengLu, YongYu, XiaLiu, PengyuanZheng 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.1 3 15-23 (9 pages)
Acetaminophen (APAP) overdose is one of the most common causes of acute liver failure. The study aimed to investigate the protective effect of carnosic acid (CA) on APAP-induced acute hepatotoxicity and its underlying mechanism in mice. To induce hepatotoxicity, APAP solution (400 mg/kg) was administered into mice by intraperitoneal injection. Histological analysis revealed that CA treatment significantly ameliorated APAP-induced hepatic necrosis. The levels of both alanine aminotransferase... -
Dieckol Attenuates Microglia-mediated Neuronal Cell Death via ERK, Akt and NADPH Oxidase-mediated Pathways
YanjiCui, Jee-YunPark, JinjiWu, JiHyungLee, Yoon-SilYang, Moon-SeokKang, Sung-CherlJung, JooMinPark, Eun-SookYoo, Seong-HoKim, SangmeeAhnJ 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.3 5 219-228 (10 pages)
Excessive microglial activation and subsequent neuroinflammation lead to synaptic loss and dysfunction as well as neuronal cell death, which are involved in the pathogenesis and progression of several neurodegenerative diseases. Thus, the regulation of microglial activation has been evaluated as effective therapeutic strategies. Although dieckol (DEK), one of the phlorotannins isolated from marine brown alga Ecklonia cava, has been previously reported to inhibit microglial activation, the... -
Induction of Heme Oxygenase-1 by Traditional Herb Mix Extract Improves MKN-74 Cell Survival and Reduces Stomach Bleeding in Rats by Ethanol and Aspirin in vivo
YoungJinKang, HyungSukMoon, HyeJungKim, HanGeukSeo, JaeHeunLee, KiChurlChang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.2 4 65-70 (6 pages)
of HO-1 but not COX-2, iNOS was significantly increased by HMX. Furthermore, HO-1 inhibitor, SnPP IX reduced the HO-1 activity and reversed the survival rate in HMX-treated MKN-74 cells. There's no difference between RAW 264.7 cells and MKN-74 cells. We, thus, concluded that HMX is beneficial for protection from oxidative injury, and induction of HO-1 by HMX in gastric cells is, at least, responsible for protection from oxidative stress such as ethanol, aspirin and possibly H. pylori infection. -
서장경으로부터 분리한 Homosyringaldehyde의 뇌신경세포 보호 활성
원진배, 이보형, 윤보라, 이지우, 마충제, Weon. Jin Bae, Lee. Bohyoung, Yun. Bo-Ra, Lee. Jiwoo, Ma. Choong Je 대한약학회 약학회지 5 Pages
대한약학회 약학회지 2012, Vol.56 No.5 299-303 (5 pages)
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Neuroprotective and Free Radical Scavenging Activities of Phenolic Compounds from Hovenia dulcis
Li. Gao, Min. Byung-Sun, Zheng. Chang-Ji, Lee. Joong-Ku, Oh. Sei-Ryang, Ahn. Kyung-Seop, Lee. Hyeong-Kyu 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 6 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2005, Vol.28 No.7 804-809 (6 pages)
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감송향물추출물의 HO-1 발현 촉진을 통한 세포보호 작용 및 항염작용
박철, 정민, 서은아, 권강범, 유도곤, Park. Chul, Zheng. Min, Seo. Eun-A, Kwon. Kang-Beom, Ryu. Do-Gon 대한동의생리학회 동의생리병리학회지 6 Pages
대한동의생리학회 동의생리병리학회지 2010, Vol.24 No.4 624-629 (6 pages)
