자료유형
발행기관
- 대한생리학회-대한약리학회(27)
- 대한생리학회(24)
- 우리말학회(24)
- 대한약리학회(15)
- 아시아장애사회학회(10)
- 대한신경정신의학회(9)
- 대한기계학회(1)
- 대한수의학회(1)
- 대한치과교정학회(1)
- 대한치과이식임플란트학회(1)
- 전력전자학회(1)
- 한국고분자학회(1)
- 한국기초간호학회(1)
- 한국미술치료학회(1)
- 한국안광학회(1)
- 한국인간발달학회(1)
간행물
- THE KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY(27)
- 대한생리학회지(24)
- 우리말연구(24)
- 대한약리학잡지(15)
- 아시아장애사회학연구(10)
- 신경정신의학(9)
- JOURNAL OF DENTAL IMPLANT RESEARCH(1)
- JOURNAL OF KOREAN BIOLOGICAL NURSING SCIENCE(1)
- JOURNAL OF POWER ELECTRONICS : JPE(1)
- JOURNAL OF VETERINARY SCIENCE(1)
- MACROMOLECULAR RESEARCH(1)
- THE KOREAN JOURNAL OF ORTHODONTICS(1)
- 대한기계학회론문집. TRANSACTIONS OF THE KOREAN SOCIETY OF MECHANICAL ENGINEERS. A. A(1)
- 미술치료연구(1)
- 인간발달연구(1)
- 한국안광학회지(1)
전체 선택해제
총 119건 검색
본문검색 결과만 보기
-
Phacoemulsification and acryl foldable intraocular lens implantation in dogs: 32 cases
Na-Young Yi, Shin-Ae Park, Man-Bok Jeong, Won-Tae Kim, Se-Eun Kim, Je-Min Chae, Kang-Moon Seo 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2006, 제 7권 제 3호 12 281-285 (5 pages)
(n = 4), hyphema (n = 3) and corneal ulcer (n = 2). The complications associated with the IOL were decenteration of the optic (n = 2) and ventral haptic displacement (n = 1). Most cases of PCO were found only around the margin of the IOL, and all eyes had vision during the observation period. In conclusion, the implantation of an acryl-foldable lens with a squared edge at the time of phacoemulsification is an effective method for preserving the central visual field of dogs with cataract. -
A STUDY ON THE EXPRESSION OF TYPE I AND TYPE II COLLAGEN GENES AND PROTEINS IN THE DEVELOPING HUMAN MANDIBLE
Yoon-Ah Kook, Sang-Cheol Kim, Eun-Cheol Kim 대한치과교정학회 The Korean Journal of Orthodontics 9 Pages
대한치과교정학회 The Korean Journal of Orthodontics 1995, 제 25권 제 6호 8 723-731 (9 pages)
Type I and type II collagens are considered the major collagens of bone and cartilage respectively. Monitoring the patterns of those gene and protein expressions during development will provide a basis for the understanding of the normal and abnormal growths. This study was undertaken to investigate the expression of collagen genes and proteins involved in the developing human mandible. Fifty embryos and fetuses were studied with Alcian blue-PAS, Masson´s Trichrome, reverse transcription... -
Inhibitory Effects of Ginsenoside Metabolites, Compound K and Protopanaxatriol, on GABAC Receptor-Mediated Ion Currents
Byung-HwanLee, Sung-HeeHwang, Sun-HyeChoi, Hyeon-JoongKim, Joon-HeeLee, Sang-MokLee, YunGyongAhn, Seung-YeolNah 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.2 3 127-132 (6 pages)
Ginsenosides, one of the active ingredients of Panax ginseng, show various pharmacological and physiological effects, and they are converted into compound K (CK) or protopanaxatriol (M4) by intestinal microorganisms. CK is a metabolite derived from protopanaxadiol (PD) ginsenosides, whereas M4 is a metabolite derived from protopanaxatriol (PT) ginsenosides. The Ճ-aminobutyric acid receptorC (GABAC) is primarily expressed in retinal bipolar cells and several regions of the brain. However,... -
Forward-Mode Na+-Ca2+ Exchange during Depolarization in the Rat Ventricular Myocytes with High EGTA
Eun-GiKim, ChangMannKo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.6 5 487-494 (8 pages)
During depolarization, extrusion of Ca2 from sarcoplasmic reticulum through forward-mode Na-Ca2 exchange was studied in the rat ventricular myocytes patch-clamped in whole-cell configuration. In order to confine the Ca2 responses in a micro-domain by limiting the Ca2 diffusion time, rat ventricular myocytes were dialyzed with high (14 mM) EGTA. K current was suppressed by substituting KCl with 105 mM CsCl and 20 mM TEA in the pipette filling solution... -
The Protective Effect of Melatonin Administration against Adriamycin-induced Cardiotoxicity in Rats
JinHan, ChungheeKim, NariKim, JuheePark, YoungchurlYang, EuiyongKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.4 6 333-342 (10 pages)
Adriamycin is a commonly used chemotherapeutic agent for cancer, including acute leukemia, lymphoma, and a number of solid human tumors. However, recent studies have recognized severe cardiotoxicity after an acute dose, which are likely the result of generation of free radicals and lipid peroxidation. Therefore, the clinical uses of adriamycin have been limited. Melatonin, the pineal gland hormone known for its ability to modulate circardian rhythm, has recently been studied in its several... -
Effect of Propofol on Ion Channels in Acutely Dissociated Dorsal Raphe Neuron of Sprague-Dawley Rats
Bong-JaeLee, Moo-IlKwon, Min-ChulShin, Youn-JungKim, Chang-JuKim, SoonAeKim, Ee-HwaKim, Joo-HoChung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.2 10 189-197 (9 pages)
To investigate propofol's effects on ionic currents induced by γ-aminobutyric acid (GABA) and glycine as well as on those produced by the nicotinic acetylcholine- and glutamate-responsive channels, rat dorsal raphe neurons were acutely dissociated and the nystatin-perforated patch-clamp technique under voltage- clamp conditions was used to observe their responses to the administration of propofol. Propofol evoked ion currents in a dose-dependent manner, and propofol (104 M) was used to... -
Electrical Stimulation Can Facilitate Vestibular Compensation Following Unilateral Labyrinthectomy in Rats
ByungRimPark, JinOkKim, MinSunKim, MoonYoungLee, JaeHyoKim, Yuan-ZheJin, MyungAeChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.2 2 123-131 (9 pages)
To investigate the effects of electrical stimulation on vestibular compensation, which is the recovery of vestibular symptoms following unilateral labyrinthectomy (UL), intermittent electrical stimulation was applied to the injured vestibular portion in Sprague-Dawley rats. Vestibuloocular and vestibulospinal reflexes, electrical activity and expression of c-Fos protein in medial vestibular nuclei (MVN) were measured with time following UL. Spontaneous nystagmus occurred with frequency of... -
Altered Delayed Rectifier K+ Current of Rabbit Coronary Arterial Myocytes in Isoproterenol-Induced Hypertrophy
NariKim, JinHan, EuiyongKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.1 5 33-40 (8 pages)
The aim of present study was to define the cellular mechanisms underlying changes in delayed rectifier K (KDR) channel function in isoproterenol-induced hypertrophy. It has been proposed that KDR channels play a role in regulation of vascular tone by limiting membrane depolarization in arterial smooth muscle cells. The alterations of the properties of coronary KDR channels have not been studied as a possible mechanism for impaired coronary reserve in cardiac hypertrophy. The present... -
Role of Gap Junctions in the Endothelium-Dependent Hyperpolarization of Vascular Smooth Muscle Cells
YoshimichiYamamoto, MeganF.Klemm, HikaruHashitani, RichardJ.Lang, TsuyoshiSoji, HikaruSuzuki 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2001, Vol.5 No.1 1 1-8 (8 pages)
Hyperpolarization of arterial smooth muscle by acetylcholine is considered to be produced by the release of an unidentified chemical substance, an endothelium-derived hyperpolarizing factor (EDHF). Several chemicals have been proposed as the candidate for EDHF. However, none of them fulfil completely the nature and property of EDHF. Ultrastructural observation with electron microscope reveals that in some arteries, gap junctions are formed between endothelial and smooth muscle cells. In small... -
The Effect of NO Donor on Contraction, Cytosolic Ca2+ Level and Ionic Currents in Guinea-pig Ileal Smooth Muscle
Seong-ChunKwon, Ki-YoungPark, Duck-SunAhn, Young-HoLee, Bok-SoonKang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.1 5 33-40 (8 pages)
This study was designed to clarify the mechanism of the inhibitory action of a nitric oxide (NO) donor, 3-morpholino-sydnonimine (SIN-1), on contraction, cytosolic Ca2 level ([Ca2]i), and ionic currents in guinea-pig ileum. SIN-1 (0.01∼100μM) inhibited 25 mM KCl- or histamine (10μM)-induced contraction in a concentration-dependent manner. SIN-1 reduced both the 25 mM KCl- and the histamine-stimulated increases in muscle tension in parallel with decreased [Ca2]i. Using... -
Responses of Dorsal Horn Neurons to Peripheral Chemical Stimulation in the Spinal Cord of Anesthetized Cats
SungJunJung, JooMinPark, JoonHoLee, JiHyeLee, Su-YongEun, SangJeongKim, Won-IlLim, SunHeeCho, JunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.1 3 15-24 (10 pages)
Although nociceptive informations are thought to be processed via different neural mechanisms depending on the types of stimuli, sufficient data have not been accumulated yet. We performed a series of experiments to elucidate the possible neural mechanisms as to chemical stimuli such as formalin, capsaicin and ATP. Single unit activity of wide dynamic range (WDR) neurons and high threshold cells were recorded extracellularly from the lumbosacral enlargement of cat spinal cord before and after... -
Role of Ca2+ in the Stimulation of Glucose Transport by Insulin in Adipocytes
Sung-HoeChang, YeonJinJang, Kun-KooPark, GhiSuKim, HeeJeongRyu, ChunSikPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.3 14 357-364 (8 pages)
We investigated the role of Ca2 and protein kinases/phosphatases in the stimulatory effect of insulin on glucose transport. In isolated rat adipocytes, the simple omission of CaCl2 from the incubation medium significantly reduced, but did not abolish, insulin-stimulated 2-deoxy glucose (2-DG) uptake. Pre-loading adipocytes with intracellular Ca2 chelator, 5,5'-dimethyl bis (o-aminophenoxy)ethane-N,N,N'N' tetraacetic acetoxymethyl ester (5,5'-dimethyl BAPTA/AM) completely blocked... -
The Effects of Sera from Amyotrophic Lateral Sclerosis Patients on Neuromuscular Transmission and Calcium Channels in Mice
HaiDunYan, JimokKim, SungJunJung, JunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 17 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.1 13 101-117 (17 pages)
Amyotrophic lateral sclerosis (ALS) is a degenerative neuromuscular disease of unknown etiology in which the upper and lower motor neurons are progressively destroyed. Recent evidences support the role of autoimmune mechanisms in the pathogenesis of ALS. This study investigated the effects of sera from ALS patients on neuromuscular transmission in phrenic nerve-hemidiaphragm preparations and on calcium currents of single isolated dorsal root ganglion (DRG) cells in mice. Mice were injected with... -
Mechanism of Membrane Hyperpolarization by Extracellular K+ in Resistance-sized Cerebral Arterial Muscle Cell of Rabbit
SeHoonKim, KunMooChoi, HoeSukKim, ByeongHwaJeon, SeokJongChang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.1 1 1-10 (10 pages)
We sought to find out the mechanism of vascular relaxation by extracellular K concentration ([K]o) in the cerebral resistant arteriole from rabbit. Single cells were isolated from the cerebral resistant arteriole, and using voltage-clamp technique barium-sensitive K currents were recorded, and their characteristics were observed. Afterwards, the changes in membrane potential and currents through the membrane caused by the change in [K]o was observed. In the smooth... -
Roles of Na+-Ca2+ Exchange in the Negative Force-Frequency Relationship
ChangMannKoSoonJinKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.6 8 715-724 (10 pages)
Frequency-force relationships (FFR) were studied in electrically field stimulated rat left atria (LA) by reducing the stimulation frequency from resting 3 Hz to test frequencies (0.1-1 Hz) for 5 minutes. The twitch amplitudes of LA elicited the typical negative staircases with 3-phased changes: the initial rapid increase, the second decrease and the following plateau at test frequencies. Verapamil (3⁓105 M) pretreatment elicited frequency-dependent suppression of the twitch... -
Further Characterization of Bombesin Like Immunoreactivities from the Skin of Korean Fire-bellied Toad, Bombina orientalis
HyeokYilKwon, HyungSeoPark, MooHoWon, YunLyulLee, HyoungJinPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.5 12 637-644 (8 pages)
Previously, we have isolated authentic bombesin and another bombesin like peptide named bombesin like immunoreactivity (BLI)-K2 from the skin of Korean fire-bellied toad, Bombina orientalis. In the present study, we have newly purified three heterogeneous forms of BLI named BLI-K3, BLI-K4, and BLI-K5 from side fractions obtained in previous isolation of bombesin like peptide. The BLIs were separated into five peaks on a column of C18 preparative HPLC. Among them, three minor peaks containing... -
Regulation of Salt and Volume Transport along the Nephron during Acute Systolic Hypertension
AliciaA.McDonough, YibinZhang, ClaraE.Magyar, AustinK.Mircheff 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.5 1 541-547 (7 pages)
-
Increased Activity of Large Conductance Ca2+-Activated K+ Channels in Negatively-Charged Lipid Membranes
JinBongParkPanDongRyu 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.4 15 529-539 (11 pages)
The effects of membrane surface charge originated from lipid head groups on ion channels were tested by analyzing the activity of single large conductance Ca2-activated K (maxi K) channel from rat skeletal muscle. The conductances and open-state probability (Po) of single maxi K channels were compared in three types of planar lipid bilayers formed from a neutral phosphatidylethanolamine (PE) or two negatively-charged phospholipids, phosphatidylserine (PS) and phosphatidylinositol... -
Altered Renal Nitric Oxide System in Experimental Hypertensive Rats
EunSukYang, JongUnLee, DaeGillKang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.4 7 455-460 (6 pages)
The present study was aimed at investigating whether the development of hypertension is related with an altered expression of nitric oxide synthases (NOS) in the kidney. By Western blot analysis, the expression of bNOS and ecNOS isoforms was determined in the kidney of deoxycorticosterone acetate (DOCA)-salt and two-kidney, one clip (2K1C) rats. In DOCA-salt hypertension, the expression of both bNOS and ecNOS was decreased, along with tissue contents of nitrites. In 2K1C hypertension, the... -
Hydroxyl Radical-Mediated Commitment of HL-60 Cells to Differentiation Modulation of Differentiation Process by Phosphodiesterase Inhibitors
YoungJinCho, WoongShickAhn, SeokHoCha, Kweon-HaengLee, WonIlKim, MyungHeeChung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.3 12 369-376 (8 pages)
This report shows that hydroxyl radical, generated by a Fenton reaction involving adenosine 5'-diphosphate/Fe2+ complex (5-15 ㄍM) and H2O2 (2 ㄍM), induced differentiation of HL-60 cells in a dose- and time-dependent manner. This is evidenced by the increases in 12-O-tetradecanoylphorbol 13-acetate- and fMLP-stimulated superoxide production capability. The cells exposed to hydroxyl radical for defined periods (24∼96 hr) continued to differentiate even after the hydroxyl radical... -
Electrolysis of Physiological Salt Solution Generates a Factor that Relaxes Vascular Smooth Muscle
Pil-OhSongKi-ChurlChang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.2 10 217-223 (7 pages)
Oxygen-derived free radicals have been implicated in many important functions in the biological system. Electrical field stimulation (EFS) causes arterial relaxation in animal models. We found that EFS applied to neither muscle nor nerve but to Krebs solution caused a relaxation of rat aorta that had been contracted with phenylephrine. In the present study, therefore, we investigated the characteristics of this EIRF (electrolysis-induced relaxing factor) using rat isolated aorta. Results... -
Inhibitory Effects of Ginseng Saponins on c-fos mRNA Expression and the Proliferation of Rat Aortic Vascular Smooth Muscle Cells Stimulated by Angiotensin II
WoongChoi, JinYoungJung, HunSikKim, YeoPyoYun, JongDaePark, HeeYulAhn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.2 8 201-207 (7 pages)
To evaluate the possibility that the ginseng saponins could be developed as an anti-arteriosclerotic agent, we examined the inhibitory effects of ginseng saponins (total saponin[TS], panaxatriol[PT], panaxadiol[PD]) on the expression of c-fos mRNA and the proliferation of cultured rat aortic vascular smooth muscle cells (VSMCs) stimulated by angiotensin II (Ang II). TS and PT (1.0 mg/ml) suppressed c-fos mRNA induction in VSMCs stimulated by 10-5 M Ang II. The order of inhibitory potency was... -
External pH Effects on Delayed Rectifier K+ Currents of Small Dorsal Root Ganglion Neuron of Rat
YoungHoKim, JungHyunHahn, InJaLim, SungkwonChung, HyoWeonBang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.2 4 165-172 (8 pages)
Under certain pathophysiological conditions, such as inflammation and ischemia, the concentration of H+ ion in the tissue surrounding neurons is changed. Variations in H+ concentration are known to alter the conduction and/of the gating properties of several types of ion channels. Several types of K+ channels are modulated by pH. In this study, the whole cell configuration of the patch clamp technique has been applied to the recording of the responses of change of external pH on the delayed... -
기니픽의 회장평활근에서 NANC 신경전달물질의 작용기전
이영호, 김종훈, 강복순 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 14 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.6 20 783-796 (14 pages)
Action Mechanisms of NANC Neurotransmitters in Smooth Muscle of Guinea Pig Ileum. 2 -. T1IO .. n r 1 Young-Ho Lee'， Jong-Hoon Kim -
동방결절에서 과분극에 의해 활성화되는 내향전류에 대한 Cyclic-GMP의 영향 Effects of Cyclic-GMP on Hyperpolarization-activated inward Current (If) in Sino-atrial Node Cells of Rabbit
유신, 호원경, 엄융의, ShinYoo, Won-KyungHo, YungEEarm 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.6 14 731-739 (9 pages)
The aim of present study is to investigate the effects of cGMP on hyperpolarization activated inward current (If), pacemaker current of the heart, in rabbit sino-atrial node cells using the whole-cell patch clamp technique. When sodium nitroprusside (SNP, 80μM), which is known to activate guanylyl cyclase, was added, If amplitude was increased and its activation was accelerated. However, when If was prestimulated by isopreterenol (ISO, 1μM), SNP reversed the effect of ISO. In the absence of... -
흰쥐 심근의 역 사다리 효과에 있어서 생후 연령에 따른 Na+-Ca2+ 교환의 역할에 관한 연구 Studies on the Roles of Na+-Ca2+ Exchange according to Postnatal Age in the Negative Staircase Effect of the Rat Heart
이해용, 김순진, 고창만, Hae-yongLee, SoonJinKimChangMannKo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.6 12 707-716 (10 pages)
Recent reports revealed that the Na-Ca2 exchangers and feet structures of sarcoplasmic reticulum(SR) are located in close vicinity in the specific compartment. Therefore, we investigated the possibility that the Na-Ca2 exchanger may decrease the tension development by transporting the Ca2 out of the cell right after it released from SR, on the basis of this anatomical proximity. We exammined the negative force-frequency relationship of the developed tension in... -
Effect of pH on the ATP-sensitive K+ Channel in Aortic Smooth Muscle Cells from Rats
SeHoonKim, IlSuKim, HoeSukKim, ByeongHwaJeon, SeokJongChang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.5 11 555-563 (9 pages)
The effects of pH on K currents were investigated in single smooth muscle cells isolated from the thoracic aorta of Wistar-Kyoto rats. Whole-cell K currents were recorded in the conventional configuration of the voltage-clamp technique. Pinacidil (10uM) activated the whole-cell current and the pinacidil-activated current was completely inhibited by glibenclamide (10uM) , an inhibitor of ATP-sensitive K channel (KATP channel). Pinacidil-activated current was reversed at near... -
The Influence of N6-cyclopentyladenosine and Magnesium on Norepinephrine Release in the Rat Hippocampus
YeungBongPark, SangDukPark, BongKyuChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 3 135-142 (8 pages)
As it has been reported that the depolarization-induced norepinephrine (NE) release is modulated by activation of presynaptic A1-adenosine heteroreceptor and various lines of evidence indicate that A2-adenosine receptor also presents in hippocampus, and that the adenosine effect is magnesium dependent, the present study was undertaken to delineate the role of adenosine receptors in the modulation of hippocampal NE release. Slices from the rat hippocampus were equilibrated with [3H]-NE and the... -
Inhibition of Phospholipase A2 Diminishes the Acute Alveolar Injury Induced by Interleukin-1
YoungManLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.1 9 71-78 (8 pages)
In an attempt to investigate the role of phospholipase A2(PLA2) in interleukin-1 (IL-1) induced acute lung injury, mepacrine was tried to inhibit PLA2 in IL-1 induced ARDS rats. For confirmation of acute lung injury by IL-1, and to know the role of neutrophils in this injury, lung leak index, lung myeloperoxidase(MPO), number of neutrophils and protein content in the bronchoalveolar lavage (BAL) and wet lung weight were measured. At the same time lung PLA2 was measured to know the effect of... -
Meprobamate Chlorpromazine 및 電擊療法이 白鼠의 Estrous Cycle에 미치는 影響
羅鳳鎭, 朱鐘球, 金恩洗, 金光曰 대한신경정신의학회 신경정신의학 6 Pages
대한신경정신의학회 신경정신의학 1966, 제 5권 제 1호 14 59-64 (6 pages)
-
Lithium 및 數種 睡眼劑가 家兎 血中酒精濃度에 미치는 影響에 關한 實驗的 研究
金核, 眞鑛建, 李起蘇, 白尙昌 대한신경정신의학회 신경정신의학 12 Pages
대한신경정신의학회 신경정신의학 1972, 제 11권 제 4호 5 243-254 (12 pages)
-
-
Nialamide 및 Lithium 이 가토 혈중 알콜 농도에 미치는 영향에 관한 실험적 연구
대한신경정신의학회 신경정신의학 1975, 제 14권 제 4호 12 453-459 (7 pages)
-
불면증에 대한 L-Tryptophan의 임상적 효과
김문엽, 정희연 대한신경정신의학회 신경정신의학 9 Pages
대한신경정신의학회 신경정신의학 1985, 제 24권 제 2호 20 335-343 (9 pages)
-
酒精投與 및 禁斷이 白鼠 腦 및 肝 Adenosine Triphosphatase 活性에 미치는 影響
田珍淑, 張焕, , 金亀, 子 대한신경정신의학회 신경정신의학 31 Pages
대한신경정신의학회 신경정신의학 1986, 제 25권 제 2호 3 235-265 (31 pages)
-
소동통우울증과 다동통우울증간의 통각내성치에 대한 Naloxone 효과의 차이
박제민, 김명정 대한신경정신의학회 신경정신의학 13 Pages
대한신경정신의학회 신경정신의학 1986, 제 25권 제 3호 6 388-400 (13 pages)
-
Catecholamines에 관(關)하여 -제5편(第五編) : 자궁(子宮) catecholamines에 관한 실험적(實驗的) 연구(硏究)-
이우주(Woo Choo Lee) 대한약리학회 대한약리학잡지 24 Pages
대한약리학회 대한약리학잡지 1983, 제 19권 제 1호 2 37-60 (24 pages)
-
복합경구피임제 복용이 혈청 지질함량에 미치는 영향
김정희(J.H. Kim), 김원준(W.J. Kim) 대한약리학회 대한약리학잡지 6 Pages
대한약리학회 대한약리학잡지 1981, 제 17권 제 2호 8 69-74 (6 pages)
-
McN-A-343, Clonidine 및 Cocaine의 백서(白鼠)와 가토정관(家兎精管)의 자극효과(刺戟效果)에 대(對)한 영향(影響)
양효구(Hyo Koo Yang) 대한약리학회 대한약리학잡지 8 Pages
대한약리학회 대한약리학잡지 1981, 제 17권 제 2호 3 23-30 (8 pages)
1) 흰쥐 및 가토정관표본(家兎精管標本)에서 전기자극(電氣刺戟)(Field Stimulation)에 의한 수축반응(收縮反應)에 미치는 McN-A-343. cocain 및 clonidine등 그 작용(作用)에 NE와의 유관성(有關性)이 시사(示唆)되어 있는 약물(藥物)의 영향(影響)을 조사(調査)하였다. 2) 소양(小量)의 McN-A-343(0.003, 0.03, 0.3μ g/ml), clonidine(0.003, 0.03μg/ml), cocaine(0.03μg/ml)존재하(存在下)에서 5 ~ 10Hz에 의한 자극효과(刺戟效果)는 억제(抑制)되었고 이 억제(抑制)는 yohimbine, piperoxan 투여(投與)에 의하여... -
두개내압상승(頭蓋內壓上昇)에 따른 혈압상승(血壓上昇)과 교감신경기능(交感神經機能)과의 관계(關係) -Clonidine, phenoxybenzamine 및 phentolamine의 영향(影響)-
정우섭(Woo Sup Chung) 대한약리학회 대한약리학잡지 6 Pages
대한약리학회 대한약리학잡지 제 15권 제 1,2호 2 7-12 (6 pages)
1. 두개내압상승(頭蓋內壓上昇)에 혈압상승(血壓上昇)이 중추(中樞)의 교감신경기능(交感神經機能)과의 관계(關係)가 있음을 확인(確認)하기 위하여, clonidine, phenoxybenzamine 및 phentolamine을 사용(使用)하여 이들 약물(藥物)이 두 개내압상승(頭蓋內壓上昇)에 따른 협압상승(血壓上昇)에 미치는 영향(影響)을 조사(調査)하였다. 2. 정맥내(靜脈內) clonidine은 측뇌실내(側腦室內) 주입시(注入時)와 같이 두개내압상승(頭蓋內壓上昇)에 따른 혈압상승(血壓上昇)을 억제(抑制)하였다. 3. Phenoxybenzamine 및 phentolamine의... -
취조직 재생능에 관한 실험
이명선(M.S. Lee), 이선영(S.Y. Lee) 대한약리학회 대한약리학잡지 8 Pages
대한약리학회 대한약리학잡지 제 14권 제 1,2호 6 47-54 (8 pages)
-
뇌내(腦內) Norepinephrine, Clonldine에 의한 심박(心搏) 및 혈압변동(血壓變動)에 관한 연구(硏究)
이정청(Jung Chung Lee) 대한약리학회 대한약리학잡지 12 Pages
대한약리학회 대한약리학잡지 제 14권 제 1,2호 2 13-24 (12 pages)
1) Urethane 마취가토(痲醉家兎)의 내뇌(腦內)(측뇌실(刻腦室) 또는 소뇌연수조내(小腦延髓槽內)에 norepinephrine (NE), clonidine을 주입(注入)할 때 일어나는 심박감소(心搏減少), 혈압하강(血壓下降)에 관한 이들 약물(藥物)의 작용점(作用點)을 조사(調査)할 것을 시도(試圖)하였다. 2) NE의 뇌내주입(腦內注入)은 심박감소(心搏減少)를 일으켰으나 혈압(血壓)에 미치는 영향(影響)은 뚜렷치 않았다. Clonidine은 심박감소(心搏減少), 혈압하강(血壓下降)을 일으켰다. 3) 측뇌실내주입(刻腦室內注入)... -
황련성분의 혈압하강 작용
곽인숙(I.S. Kwak), 이상복(S.B. Lee), 조병헌(B.H. Cho), 조규철(K.C. Cho) 대한약리학회 대한약리학잡지 5 Pages
대한약리학회 대한약리학잡지 1976, 제 12권 제 2호 8 61-65 (5 pages)
-
흰쥐의 위산(胃酸)분비에 대한 고장(高張)포도당용액의 영향
김혜영(H.Y. Kim), 조태순(T.S. Cho), 홍사석(S.S. Hong) 대한약리학회 대한약리학잡지 6 Pages
대한약리학회 대한약리학잡지 1976, 제 12권 제 1호 6 57-62 (6 pages)
-
가토(家兎)에서 Nicotine, DMPP, McN-A-343, AHR-602, Tyramine, Angiotensin, Neostigmine이 심박증가(心博增加)를 일으키는 작용점(作用點)에 관한 연구(硏究)
박평순(Pyong-Soon Bark) 대한약리학회 대한약리학잡지 12 Pages
대한약리학회 대한약리학잡지 1975, 제 11권 제 2호 4 29-40 (12 pages)
1. 척수가토(脊髓家兎)에서 nicotine, DMPP, McN-A-343, AHR-602, tyramine, angiotensin및 neostigmine에 의한 심박증가(心搏增加)의 작용점(作用點)을 조사(調査)하였다. 2. 상기약물(上記藥物)에 의한 심박증가(心搏增加)는 reserpine 처리가토(處理家兎)에서는 대단히 약(弱)하였고, Propranolol 투여후(投與後)에는 거의 나타나지 않았다. 3. Tetrodotoxin, guanethidine은 isoproterenol, nicotine, DMPP, tyramine에 의한 심박증가(心搏增加)에는 영향(影響)을 미치지 않았으나 McN-A-343, AHR-602, angiotensin, neostigmine에... -
Prostaglandins와 여성생식기(女性生殖器) 계통(系統)
홍기환(Ki-Whan Hong), 김해성(Hae-Sung Kim) 대한약리학회 대한약리학잡지 19 Pages
대한약리학회 대한약리학잡지 1975, 제 11권 제 1호 9 61-79 (19 pages)
