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Absorption Promoters in the Rectal Absorption of Drugs
Yata. Noboru 한국약제학회 藥劑學會誌 15 Pages
한국약제학회 藥劑學會誌 1985, Vol.15 No.4 231-245 (15 pages)
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Intestinal Absorption of Fibrinolytic and Proteolytic Lumbrokinase Extracted from Earthworm, Eisenia andrei
XiangMeiYan, Chung-HyoKim, ChulKyuLee, JangSikShin, IlHwanCho, UyDongSohn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.2 2 71-75 (5 pages)
To investigate the intestinal absorption of a fibrinolytic and proteolytic lumbrokinase extracted from Eisenia andrei, we used rat everted gut sacs and an in situ closed-loop recirculation method. We extracted lumbrokinase from Eisenia andrei, and then raised polyclonal antibody against lumbrokinase. Fibrinolytic activity and proteolytic activity in the serosal side of rat everted gut sacs incubated with lumbrokinase showed dose- and time-dependent patterns. Immunological results obtained by... -
Evaluation of a fixed-dose combination of benazepril and pimobendan in dogs with congestive heart failure: a randomized non-inferiority clinical trial
Jonathan N. King, Atsushi Hirakawa, Junko Sonobe, Hiroshi Otaki, Nobuhiro Sakakibara, Wolfgang Seewald, Sophie Forster 대한수의학회 Journal of Veterinary Science 12 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 1호 15 117-128 (12 pages)
A fixed-dose combination tablet of benazepril and pimobendan (Fortekor Plus; Elanco Animal Health) was tested in dogs with congestive heart failure (CHF) caused by myxomatous mitral valve disease (MMVD) in a three-arm, masked, randomized, non-inferiority clinical trial in Japan. The test group (n = 34) received Fortekor Plus twice daily. Two control groups received registered formulations of benazepril (Fortekor; Elanco Animal Health) and pimobendan (Vetmedin; Boehringer Ingelheim Vetmedica)... -
Pharmacokinetics of tilmicosin in healthy pigs and in pigs experimentally infected with Haemophilus parasuis
Ling Zhang, Li Zhao, Yonghong Liu, Junfeng Liu, Xianqiang Li 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2017, 제 18권 제 4호 2 431-437 (7 pages)
by using WinNonlin software. After TIL administration, the main PK parameters of TIL in healthy and H. parasuis-infected pigs were as follows: Area under the concentration-time curve, maximal drug concentration, half-life of the absorption phase, half-life of the distribution phase, and half-life of the elimination phase were 34.86 ± 9.69 vs. 28.73 ± 6.18 μgㆍh/mL, 1.77 ± 0.33 vs. 1.67 ± 0.28 μg/mL, 2.27 ± 0.45 vs. 2.24 ± 0.44 h, 5.35 ± 1.40 vs. 4.61 ± 0.35 h, and 43.53 ± 8.17 vs.... -
Effect of serum-derived albumin scaffold and canine adipose tissue-derived mesenchymal stem cells on osteogenesis in canine segmental bone defect model
Daeyoung Yoon, Byung-Jae Kang, Yongsun Kim, Seung Hoon Lee, Daeun Rhew, Wan Hee Kim, Oh-Kyeong Kweon 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 4호 2 397-404 (8 pages)
Composite biological and synthetic grafts with progenitor cells offer an alternative approach to auto- or allografts for fracture repair. This study was conducted to evaluate osteogenesis of autologous serum-derived albumin (ASA) scaffolds seeded with canine adipose tissue-derived mesenchymal stem cells (Ad-MSCs) in a canine segmental bone defect model. ASA scaffold was prepared with canine serum using cross-linking and freeze-drying procedures. Beta-tricalcium phosphate (β-TCP) was mixed at... -
Oxidative response of neutrophils to platelet-activating factor is altered during acute ruminal acidosis induced by oligofructose in heifers
Claudia Concha, María Daniella Carretta, Pablo Alarcón, Ivan Conejeros, Diego Gallardo, Alejandra Isabel H 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 2호 7 217-224 (8 pages)
Reactive oxygen species (ROS) production is one of the main mechanisms used to kill microbes during innate immune response. D-lactic acid, which is augmented during acute ruminal acidosis, reduces platelet activating factor (PAF)-induced ROS production and L-selectin shedding in bovine neutrophils in vitro. This study was conducted to investigate whether acute ruminal acidosis induced by acute oligofructose overload in heifers interferes with ROS production and L-selectin shedding in blood... -
An overview of calf diarrhea - infectious etiology, diagnosis, and intervention
Yong-il Cho, Kyoung-Jin Yoon* 대한수의학회 Journal of Veterinary Science 17 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 1호 1 1-17 (17 pages)
Calf diarrhea is a commonly reported disease in young animals, and still a major cause of productivity and economic loss to cattle producers worldwide. In the report of the 2007 National Animal Health Monitoring System for U.S. dairy, half of the deaths among unweaned calves was attributed to diarrhea. Multiple pathogens are known or postulated to cause or contribute to calf diarrhea development. Other factors including both the environment and management practices influence disease severity or... -
All blood, No stool: enterohemorrhagic Escherichia coli O157:H7 infection
Jang W. Yoon, Carolyn J. Hovde 대한수의학회 Journal of Veterinary Science 14 Pages
대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 3호 1 219-232 (14 pages)
Enterohemorrhagic Escherichia coli serotype O157:H7 is a pathotype of diarrheagenic E. coli that produces one or more Shiga toxins, forms a characteristic histopathology described as attaching and effacing lesions, and possesses the large virulence plasmid pO157. The bacterium is recognized worldwide, especially in developed countries, as an emerging food-borne bacterial pathogen, which causes disease in humans and in some animals. Healthy cattle are the principal and natural reservoir of E.... -
Hepatic encephalomyelopathy in a calf with congenital portosystemic shunt (CPSS)
Valeria Cafe Marcal, *, Anna Oevermann, Tim Bley, Patrizia Pfister4, Julien Miclard1 대한수의학회 Journal of Veterinary Science 3 Pages
대한수의학회 Journal of Veterinary Science 2008, 제 9권 제 1호 16 113-115 (3 pages)
A 4-month-old female Holstein Friesian calf was referred to the Veterinary Teaching Hospital, University of Berne, Switzerland for evaluation of ataxia, weakness, apathy and stunted growth. Clinical examination revealed generalized ataxia, propioceptive deficits, decreased menace response and sensibility. Postmortem examination did not reveal macroscopic changes of major organs. Histologically, the brain and the spinal cord lesions were characterized by polymicrocavitation, preferentially... -
An immunohistochemical study of chromogranin A and Sp-1 immunoreactive cells in the gastrointestinal tract of ovariectomized rats
Sae Kwang Ku, Hyeung Sik Lee, Jae Hyun Lee 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2005, 제 6권 제 3호 3 191-196 (6 pages)
The changes on the regional distributions and frequencies of two types of chromogranin, chromogranin A (CGA) and bovine Sp-1 chromogranin (BCG)-immunoreactive (IR)cells in gastrointestinal (GI)tract of osteoporotic Sprague-Dawley rat induced by ovariectomy were studied by immunohistochemical methods. The experimental animals were divided into two groups, one is non-ovariectomized group (Sham)and the other is ovariectomized group (OVX). Samples were collected from each part of GI tract at 10th... -
Calcium metabolism in cows receiving an intramuscular injection of 1,25-dihydroxyvitamin D3 combined with prostaglandin F2?? closely before parturition
Norio Yamagishi, Yu Ayukawa, Inhyung Lee, Kenji Oboshi, Yoshihisa Naito 대한수의학회 Journal of Veterinary Science 3 Pages
대한수의학회 Journal of Veterinary Science 2005, 제 6권 제 2호 13 165-167 (3 pages)
To determine the effect of exogenous 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] combined with induced parturition on calcium (Ca) metabolism, cows received a single intramuscular injection of 1,25(OH)2D3 and prostaglandin F2α (PGF2α) closely before calving. Ten late-pregnant, multiparous Holstein cows were assigned to 1,25(OH)2D3 group (five treated with both 1,25(OH)2D3 and PGF2α) and control group (five treated with PGF2α). 1,25(OH)2D3 group showed an increase in plasma Ca concentration around... -
Effect of intratesticular injection of xylazine/ketamine combination on canine castration
Joon-ki Kim, Seong-mok Jeong, Na-Young Yi, Man-Bok Jeong, Eun-song Lee, Tchi-chou Nam, Kang-moon Seo 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2004, 제 5권 제 2호 10 151-155 (5 pages)
of administration did not affect rectal temperature. Mean induction time was significantly (p < 0.05) longer in IT group than in IM and IV groups. On the contrary, mean arousal time and mean walking time were shortened in IT group. Clinical signs related to pain response at the time of injection and vomiting were less observed in IT group than in IM group, and head shaking was less shown in IT group than in IM and IV groups during recovery period. These results indicated that intratesticular... -
Analgesic effect of caudal epidural ketamine in cattle
Inhyung Lee, Tomo Yoshiuchi, Norio Yamagishi, Kenji Oboshi, Yu Ayukawa, Naoki Sasaki, Haruo Yamada 대한수의학회 Journal of Veterinary Science 4 Pages
대한수의학회 Journal of Veterinary Science 2003, 제 4권 제 3호 10 261-264 (4 pages)
This study was performed to clarify the analgesic effect of ketamine injected into the first intercoccygeal (Co1- Co2) epidural space in standing cattle. Five adult cows were randomly received 3 treatments at least 1 week interval: 5, 10 and 20 mL of 5% ketamine. Sedation, analgesia, ataxia and other effects on cardiopulmonary and rumen functions were assessed before ketamine administration and until 120 min. The analgesia without sedation was shown at tail and perineum about 5 min after all... -
Effect of fever on pharmacokinetics and dosage regimen of intramuscularly administered amikacin in goats
A. K. Agrawal, S. D. Singh, C. Jayachandran 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2001, 제 2권 제 2호 4 91-96 (6 pages)
condition at most of the time intervals. Various pharmacokinetic parameters like t(1/2), AUC, AUMC, MRT and Vd(area) were significantly higher whereas total body clearance (Cl(B)) was significantly lower in febrile goats as compared to normal goats. Absorption half-life (t(1/2) ka) value differed non-significantly. For maintaining mean therapeutic level of 2 mg/ml, a priming dose (D*) of 14.732.28 mg/kg, followed by maintenance dose (D(o)) of 13.952.28 mg/kg at shorter dosage interval (t) of 8 h... -
원저 : 개 파보바이러스성 장염에 대한 난황항체의 예방 및 치료 효과
오경은, 정석영, 김보미, 장상호, 이남형, 조영재, 김두, 최정훈, 한태욱 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 7 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2014, 제 54권 제 2호 1 67-73 (7 pages)
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Original Article : Preoperative administration effect of metronidazole, ceftriaxone sodium and their combination on stenotic index of jejunal anastomotic segment of dogs
Rehan Rafique , Muhammad Nadeem Asi , Muhammad Saqib , Muhammad Hammad Hussain , Awais Ur Rehman Sial , Aqsa Mushtaq 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 4 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2014, 제 54권 제 1호 5 27-30 (4 pages)
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Intrahepatic portosystemic shunt with a second degree atrioventricular block fixed by transvenous coil embolization in a dog
Seung Gon Lee , So Jeong Nam , Hyun Wook Kim , Chang Baig Hyun , 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 8 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2008, 제 48권 제 4호 15 493-500 (8 pages)
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Anti-inflammatory Effects of Flavonoids on TNBS-induced Colitis of Rats
MinjaeJoo, HanSangKim, TaeHoonKwon, AlishaPalikhe, TinSarZaw, JiHoonJeong, UyDongSohn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.1 7 43-50 (8 pages)
It has been shown that the extracts including eupatilin and quercetin-3-β-D-glucuronopyranoside had mucoprotective effects on the esophagus and stomach through their antioxidant activities. This study was designed to investigate the anti-inflammatory effect of these flavonoid compounds in an animal model of inflammatory bowel disease induced by 2,4,6-trinitrobenzene sulfonic acid. Experimental colitis was induced by intracolonic administration of 2,4,6-trinitrobenzene sulfonic acid. Extracts... -
Comparison of Vasodilator Effects of Platycodin D and D3 in Rats
Dong-YoonLim, Byeong-CheolKim, Eun-BangLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.3 5 149-155 (7 pages)
The aim of the present study was to examine the effects of platycodin D and D3, which are active components derived from the roots of Platycodon grandiflorum A. DC., on the contractile force of the i3olated rat aorta and blood pressure of the anesthetized rat, and also to elucidate its mechanism of action. Both phenylephrine (an adrenergic α1-receptor agonist) and high potassium (a membrane- depolarizing agent) caused great contractile responses in the isolated aortic strips. Platycodin D at... -
복강경 수술에서 기복제 이산화탄소의 37℃ 가온이 수술 중 체온, 수축기압 및 심박동수와 산염기 균형에 미치는 영향
박진일, 윤혜상 한국기초간호학회 Journal of Korean Biological Nursing Science 10 Pages
한국기초간호학회 Journal of Korean Biological Nursing Science 2017, Volume 19, No 2 4 76-85 (10 pages)
복강경 수술은 도입 초기에 여성의 불임시술, 충수돌기절제술과 담낭절제술 등의 단시간 수술에 이용하였지만 최근에는 3시간 이상 소요되는 대장절제술에 이용될 정도로 적용 범위가 확대되고 있다[1]. 복강경 수술은 개복술과 비교하여 통증이 적고, 회복이 신속하여 재원기간이 짧고, 수술 후 일상생활에의 복귀가 신속하다 -
Carbon Fibers for the Repair of Abdominal Wall Defects in Rabbits
A.K.Gangwar, A.K.Sharma, Naveen Kumar, S.K.Maiti, N.Kumar, S.K.Ma 한국탄소학회 Carbon Letters 10 Pages
한국탄소학회 Carbon Letters 2005, Vol.6 No.1 3 15-24 (10 pages)
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Inclusion Complex of Analgesic and antiinflammatory Agents with Cyclodextrins (II) : Effect of $2-Hydroxypropyl-{eta}-cyclodextrin$ on the Release of Ibuprofen Suppository
오인준, 이미영, 이용복, 신상철, Oh. In-Joon, Lee. Mi-Young, Lee. Yong-Bok, Shin. Sang-Chul 한국약제학회 藥劑學會誌 7 Pages
한국약제학회 藥劑學會誌 1997, Vol.27 No.3 165-171 (7 pages)
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폴리비닐알코올 하이드로겔 캅셀을 삽입한 중공좌제로부터 염산프로프라놀롤의 조절 방출
진선경, 문이렌, 구영순 대한약학회 약학회지 10 Pages
대한약학회 약학회지 1999, Vol.43 No.2 150-159 (10 pages)
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아세트아미노펜 좌제의 용출과 직장흡수
한정선, 심창구, 김신근 대한약학회 약학회지 10 Pages
대한약학회 약학회지 1987, Vol.31 No.5 286-295 (10 pages)
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중쇄지방산염 함유 Eudispert hv 하이드로겔의 인슐린 직장 흡수증대효과
한건, 김준식, 유정희, 정연복, Han. Kun, Kim. Joun-Sik, Yoo. Jeoung-Hee, Chung. Youn-Bok 한국약제학회 藥劑學會誌 10 Pages
한국약제학회 藥劑學會誌 1997, Vol.27 No.3 189-198 (10 pages)
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염산 프로프라놀롤-고체 분산계-폴리비닐알코올 하이드로겔 중공좌제로부터의 약물방출
정진훈, 이정연, 구영순, Chung. Jeen-Hoon, Lee. Jeong-Yeon, Ku. Young-Soon 한국약제학회 藥劑學會誌 10 Pages
한국약제학회 藥劑學會誌 1996, Vol.26 No.4 299-308 (10 pages)
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이부프로펜 리지네이트의 직장흡수에 미치는 좌제기제 및 첨가제의 영향
전홍렬, 박동우, 이승목, 이정우, 최영욱, Jeon. Hong-Ryeol, Park. Dong-Woo, Lee. Seung-Mok, Yi. Jung-Woo, Choi. Young-Wook 한국약제학회 藥劑學會誌 9 Pages
한국약제학회 藥劑學會誌 1994, Vol.24 No.3 145-153 (9 pages)
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푸로푸라놀롤 좌제 개발에 관한 연구
김가나, 최준식, 이진환, Kim. Ga-Na, Choi. Jun-Shik, Lee. Jin-Hwan 한국약제학회 藥劑學會誌 6 Pages
한국약제학회 藥劑學會誌 1991, Vol.21 No.2 73-78 (6 pages)
