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총 1,234건 검색
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대한수의학회 대한수의학회 학술대회발표집 춘계학술심포지움 91 134-134 (1 pages)
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Netrin-1-Induced Stem Cell Bioactivity Contributes to the Regeneration of Injured Tissues via the Lipid Raft-Dependent Integrin α6β4 Signaling Pathway
Sei Jung Lee, Hyeon Su Lim, Jun Sung Kim, So Hee Ko, Xaykham Onphachanh, Ho Jae Han 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 춘계학술심포지움 33 100-101 (2 pages)
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The effect of intravenous injection of human adipose derived stem cell conditioned medium on ovulation and subsequent embryo development in aged mice
Kihae Ra, Geon A Kim, Hyun Ju Oh, Sung Keun Kang, Jeong Chan Ra, Byeong Chun Lee 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 316 381-382 (2 pages)
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Transforming growth factor-beta induced epithelial- mesenchymal transition abolished without TGF-beta condition: Cancer stem cell properties and cisplatin resistance in lungcancer cell lines
Seong Kwan Kim, Jin A Park, Sang Hyun Cho, Weijia Zheing, Jeong Min Choi, Ho Chul Shin 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 232 336-337 (2 pages)
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Promoting Stem Cell Proliferation by Vegetable Resources
Mi Jeong Park, Da Un Jeong, Na Yeon Gu, Jeong Su Byeon, In Soo Cho, Sang Ho Cha, Jienny Lee 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 230 335-336 (2 pages)
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Update of stem cell therapy for orthopedic diseases of animals
Hyun Sook Park 대한수의학회 대한수의학회 학술대회발표집 1 Pages
대한수의학회 대한수의학회 학술대회발표집 추계학술심포지움 27 141-141 (1 pages)
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Clinical assessment after human adipose stem cell transplantation into dogs
Seok Hee Lee, Erif M.N. Setyawan, Yoo Bin Choi, Jeong Chan Ra, Sung Keun Kang, Byeong Chun Lee, Geon A Kim 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 3호 15 452-461 (10 pages)
Adipose tissue-derived stem cell (ASCs) are an attractive source of stem cells with therapeutic applicability in various fields for regenerating damaged tissues because of their stemness characteristics. However, little has reported on evaluating adverse responses caused by human ASC therapy. Therefore, in the present study, a clinical assessment after human ASC transplantation into dogs was undertaken. A total of 12 healthy male dogs were selected and divided into four groups: saline infusion,... -
The potential role of COX-2 in cancer stem cell-mediated canine mammary tumor initiation: an immunohistochemical study
Jian Huang, Di Zhang, Fuqiang Xie, Degui Lin 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 2호 13 225-231 (7 pages)
Increasing evidence suggests that cancer stem cells (CSCs) are responsible for tumor initiation and maintenance. Additionally, it is becoming apparent that cyclooxygenase (COX) signaling is associated with canine mammary tumor development. The goals of the present study were to investigate COX-2 expression patterns and their effect on CSC-mediated tumor initiation in primary canine mammary tissues and tumorsphere models using immunohistochemistry. Patterns of COX-2, CD44, octamer-binding... -
Suitability of autologous serum for expanding rabbit adipose-derived stem cell populations
Jae-Jun Bahn, Jin-Young Chung, Wooseok Im, Manho Kim, Sae Hoon Kim* 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2012, 제 13권 제 4호 11 413-417 (5 pages)
Adipose-derived stem cells (ASCs) are believed to have potential use for treating many illnesses. Most cells, including ASCs, are generally cultured in medium containing fetal bovine serum (FBS). However, FBS, which could induce an immune response or infection, is not recommended for clinical applications. In the present study, we evaluated the morphology, proliferation rate, and characterization of rabbit ASCs grown in medium containing autologous serum (AS) and compared these cells to ones... -
Safety and outcomes of subconjunctival allogenic mesenchymal stem cell transplantation in canine experimental corneal defects
Ju Won Kim , So Young Lee , Hee Myung Park 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 6 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2012, 제 52권 제 3호 2 157-162 (6 pages)
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Prospective validation of a novel dosing scheme for intravenous busulfan in adult patients undergoing hematopoietic stem cell transplantation
Sang-HeonCho, Jung-HeeLee, Hyeong-SeokLim, Kyoo-HyungLee, Dae-YoungKim, SangminChoe, Kyun-SeopBae, Je-HwanLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.3 3 245-251 (7 pages)
adult patients who received busulfan as conditioning therapy for hematopoietic stem cell transplantation (HCT) participated in this prospective study. Patients were randomized to receive intravenous busulfan, either as the conventional dosage (3.2 mg/kg daily) or according to the new dosing scheme based on their actual body weight (ABW) (23×ABW0.5 mg daily) targeting an area under the concentration-time curve (AUC) of 5924 μM∙min. Pharmacokinetic profiles were collected using a limited... -
Allogeneic clonal mesenchymal stem cell therapy for refractory graft-versus-host disease to standard treatment: a phase I study
HyeonGyuYi, Seung-AhYahng, InhoKim, Je-HwanLee, Chang-KiMin, JunHyungKim, ChulSooKim, SunU.Song 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.1 8 63-67 (5 pages)
Severe graft-versus-host disease (GVHD) is an often lethal complication of allogeneic hematopoietic stem cell transplantation (HSCT). The safety of clinicalgrade mesenchymal stem cells (MSCs) has been validated, but mixed results have been obtained due to heterogeneity of the MSCs. In this phase I study, the safety of bone marrow-derived homogeneous clonal MSCs (cMSCs) isolated by a new subfractionation culturing method was evaluated. cMSCs were produced in a GMP facility and intravenously... -
Effects of Human Mesenchymal Stem Cell Transplantation Combined with Polymer on Functional Recovery Following Spinal Cord Hemisection in Rats
JiSooChoi, JoongWooLeem, KyungHeeLee, Sung-SooKim, HaeyoungSuh-Kim, SeJungJung, UnJengKim, BaeHwanLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.6 6 405-411 (7 pages)
The spontaneous axon regeneration of damaged neurons is limited after spinal cord injury (SCI). Recently, mesenchymal stem cell (MSC) transplantation was proposed as a potential approach for enhancing nerve regeneration that avoids the ethical issues associated with embryonic stem cell transplantation. As SCI is a complex pathological entity, the treatment of SCI requires a multipronged approach. The purpose of the present study was to investigate the functional recovery and therapeutic... -
Effect of 5-FU and MTX on the Expression of Drug-resistance Related Cancer Stem Cell Markers in Non-small Cell Lung Cancer Cells
HeeYi, Hee-JungCho, Soo-MinCho, KyulJo, Jin-APark, Soo-HanLee, Byung-JoonChang, Jin-SukKim, Ho-ChulShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.1 2 11-16 (6 pages)
Cancer stem cells (CSCs) are often characterized by the elevated expression of drug-resistance related stem-cell surface markers, such as CD133 and ABCG2. Recently, we reported that CSCs have a high level of expression of the IL-6 receptor (IL-6R). The purpose of this study was to investigate the effect of anticancer drugs on the expression of the drug resistance-related cancer stem cell markers, ABCG2, IL-6R, and CD133 in non-small cell lung cancer (NSCLC) cell lines. A549, H460, and H23 NSCLC... -
Quantitative Phosphoproteomics of the Human Neural Stem Cell Differentiation into Oligodendrocyte by Mass Spectrometry
Cho. Kun, Kim. Jin Young, Kim. Eunmin, Park. Gun Wook, Kang. Tae Wook, Yoon. Jung Hae, Kim. Seung U., Byun. Kyunghee, Lee. Bonghee, Yoo. 한국질량분석학회 Mass spectrometry letters 8 Pages
한국질량분석학회 Mass spectrometry letters 2012, Vol.3 No.4 93-100 (8 pages)
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Expression of Recombinant Human Stem Cell Factor (hSCF) Protein using Bombyx mori Protein Disulfide Isomerase (bPDI)
Kim. Sung-Wan, Yun. Eun-Young, Kim. Seong-Ryul, Park. Seung-Won, Kang. Seok-Woo, Lee. Kwang-Gill, Kwon. O-Yu, Goo. Tae-Won 한국잠사학회 International journal of industrial entomology 5 Pages
한국잠사학회 International journal of industrial entomology 2010, Vol.21 No.2 151-155 (5 pages)
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Expression of Human Stem Cell Factor with Recombinant Baculovirus in BmN Cell Line and Silkworm
Xijie. Guo, Yongfeng. Jin, Mingguan. Yang, Yaozhou. Zhang 한국잠사학회 International journal of industrial entomology 6 Pages
한국잠사학회 International journal of industrial entomology 2002, Vol.4 No.1 51-56 (6 pages)
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Effect of Conditioning Regimen Intensity on Cytomegalovirus Infection and Related Risk Factors Analysis in Allogeneic Hematopoietic Stem Cell Transplantation
이혜민, 허윤정, 임현정, 정선영, 인용원, 정철원, 이영미, 손기호, Lee. Hye-Min, Heo. Yoon-Jeong, Im. Hyun-Jeong, Chung. Seon-Young, In. Yong-Won, Jung. Chul-Won, Lee. Y 한국임상약학회 한국임상약학회지 8 Pages
한국임상약학회 한국임상약학회지 2012, Vol.22 No.2 123-130 (8 pages)
거대세포바이러스(Cytomegalovirus; CMV) 감염은 동종조혈모세포이식 환자의 주요 사망원인 중 하나이다. 용량감소전처치(Reduced-intensity conditioning; RIC)를 이용한 조혈모세포이식은 골수억제전처치(Myeloablative conditioning; MAC)에 비해 골수억제 및 면역억제가 적으므로 CMV 감염 발생율을 감소시킬 것이라 예상되었으나 예방적 면역억제요법, T세포 제거 약제의 사용 등으로 서로 상이한 결과가 보고되고 있다. 2007년 1월부터 2009년 12월까지 총 141명의 환자(MAC 113명, RIC 28명)가 동종조혈모세포이식을 받았으며, CMV... -
Alterations of Cyclosporine Concentrations by Antibiotics in Patients with Hematopoietic Stem Cell Transplantation
송헌정, 유옥리, 최유리, 방준석, 나현오, Song. Hun-Jung, Li. Liu Yu, Choi. Yu-Ri, Bang. Joon-Seok, La. Hyen-Oh 한국임상약학회 한국임상약학회지 6 Pages
한국임상약학회 한국임상약학회지 2011, Vol.21 No.4 305-310 (6 pages)
조혈모세포이식술(또는 HSCT)을 받은 환자에게는 이식관련 부작용의 예방 또는 치료를 위해 면역억제 약물이 투여되는데, 그 중 하나인 cyclosporine은 therapeutic index가 작고 다양한 요인에 의해 혈중농도가 변화되므로 사용시에는 세심한 관찰과 조절이 필요하다. 특히 HSCT 환자에서 발생하는 호중구 감소성 발열(또는 NPF)의 치료목적으로 투여하는 항생제에 의하여 cyclosporine의 혈중농도가 변화될 수 있고, 또 임상적 경과에 따라 항생제 처방이 중도에 변경되는 경우도 빈번하지만, 실제로 항생제 처방의 중간변경에 의한... -
Acute Kidney Injury Models: Focus on the Therapeutic Effects of Stem Cell in Preclinical Approach
남현숙, 우재석, 우흥명, Nam. Hyun-Suk, Woo. Jae-Seok, Woo. Heung-Myong 한국임상수의학회 Journal of veterinary clinics 7 Pages
한국임상수의학회 Journal of veterinary clinics 2010, Vol.27 No.5 533-539 (7 pages)
최근 줄기세포를 이용한 재생의학분야의 세포치료 연구가 활발히 진행되고 있으나 상대적으로 복잡한 구조를 갖는 신장에서는 난치성 질환인 급성신부전에 대한 줄기세포 치료의 효과는 아직도 논란의 여지가 많다. 이는 연구자마다 다양한 동물모델을 사용하는 것이 한 원인으로 지적되고 있다. 본 연구에서는 줄기세포의 치료효과 분석을 위한 최적의 동물모델 조건을 확립하고자 한다. 쥐를 사용하여 세 종류의 급성신장손상모델을 다음과 같이 다양한 농도와 조건에서 분석하였다: glycerol (대조군, 8 ml/kg, 10 ml/kg), cisplatin... -
Stem Cell Biotechnology for Cell Therapy
LEE. Dong-Ree, KIM. Ha Won 한국응용약물학회 The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmaco 8 Pages
한국응용약물학회 The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmaco 2005, Vol.13 No.4 199-206 (8 pages)
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Preparation and Characterization of Genetically Engineered Mesenchymal Stem Cell Aggregates for Regenerative Medicine
Kim. Sun-Hwa, Moon. Hyung-Ho, Chung. Bong-Genn, Choi. Dong-Hoon 한국약제학회 Journal of pharmaceutical investigation 5 Pages
한국약제학회 Journal of pharmaceutical investigation 2010, Vol.40 No.6 333-337 (5 pages)
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Protection of Amyloid ${eta}$ Protein (25-35)-induced Neuronal Cell Damage by Methanol Extract of New Stem of Phyllostachys nigra Munro var. henonis Stapf in Cultured Rat Cortical Neuron
Ban. Ju-Yeon, Cho. Soon-Ock, Kwon. Soon-Ho, Kim. Jin-Bae, Song. Nak-Sul, Bae. Ki-Whan, Song. Kyung-Sik, Seng. Yeon-Hee 한국약용작물학회 韓國藥用作物學會誌 8 Pages
한국약용작물학회 韓國藥用作物學會誌 2005, Vol.13 No.2 95-102 (8 pages)
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Enhancement of Organ Regeneration in Animal Models by a Stem Cell-Stimulating Plant Mixture
Kiss. Istvan, Tibold. Antal, Halmosi. Robert, Bartha. Eva, Koltai. Katalin, Orsos. Zsuzsanna, Bujdoso. Laszlo, Ember. Istvan 한국식품영양과학회 Journal of medicinal food 6 Pages
한국식품영양과학회 Journal of medicinal food 2010, Vol.13 No.3 599-604 (6 pages)
