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1051.

Zerumbone, Sesquiterpene Photochemical from Ginger, Inhibits Angiogenesis

Ju-HyungPark, GeunMookPark, Jin-KyungKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.4 5 335-340 (6 pages)

Ju-HyungPark, GeunMookPark, Jin-KyungKim 저
...
- 3,000원
of vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1, which are key regulators of endothelial cell function and angiogenesis. In vivo matrigel plug assay in mice demonstrated significant decrease in vascularization and hemoglobin content in the plugs from zerumbone-treated mice, compared with control mice. Overall, these results suggest that zerumbone inhibits various attributes of angiogenesis, which might contribute to its reported antitumor effects.
1052.

Polymorphisms of SLC22A9 (hOAT7) in Korean Females with Osteoporosis

SeongKyuAhn, ChangKookSuh, SeokHoCha 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.4 3 319-325 (7 pages)

SeongKyuAhn, ChangKookSuh, SeokHoCha 저
...
- 3,000원
Among solute carrier proteins, the organic anion transporters (OATs) play an important role for the elimination or reabsorption of endogenous and exogenous negatively charged anionic compounds. Among OATs, SLC22A9 (hOAT7) transports estrone sulfate with high affinity. The net decrease of estrogen, especially in post-menopausal women induces rapid bone loss. The present study was performed to search the SNP within exon regions of SLC22A9 in Korean females with osteoporosis. Fifty healthy controls...
1053.

Chronic Alcohol Consumption Results in Greater Damage to the Pancreas Than to the Liver in the Rats

Seong-SuLee, Oak-KeeHong, AnesJu, Myung-JunKim, Bong-JoKim, Sung-RaeKim, Won-HoKim, Nam-HanCho6, Moo-IlKang, Sung-KooKang, Dai-JinKim, Soon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.4 2 309-318 (10 pages)

Seong-SuLee, Oak-KeeHong, AnesJu, Myung-JunKim, Bong-JoKim, Sung-RaeKim, Won-HoKim, Nam-HanCho6, Moo-IlKang, Sung-KooKang, Dai-JinKim, Soon 저
...
- 3,000원
Alcohol consumption increases the risk of type 2 diabetes. However, its effects on prediabetes or early diabetes have not been studied. We investigated endoplasmic reticulum (ER) stress in the pancreas and liver resulting from chronic alcohol consumption in the prediabetes and early stages of diabetes. We separated Otsuka Long-Evans Tokushima Fatty (OLETF) rats, a type-2 diabetic animal model, into two groups based on diabetic stage: prediabetes and early diabetes were defined as occurrence...
1054.

Effect of Sulfonylureas Administered Centrally on the Blood Glucose Level in Immobilization Stress Model

NaveenSharma, Yun-BeomSim, Soo-HyunPark, Su-MinLim, Sung-SuKim, Jun-SubJung, Jae-SeungHong, Hong-WonSuh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.3 2 197-202 (6 pages)

NaveenSharma, Yun-BeomSim, Soo-HyunPark, Su-MinLim, Sung-SuKim, Jun-SubJung, Jae-SeungHong, Hong-WonSuh 저
...
- 3,000원
Sulfonylureas are widely used as an antidiabetic drug. In the present study, the effects of sulfonylurea administered supraspinally on immobilization stress-induced blood glucose level were studied in ICR mice. Mice were once enforced into immobilization stress for 30 min and returned to the cage. The blood glucose level was measured 30, 60, and 120 min after immobilization stress initiation. We found that intracerebroventricular (i.c.v.) injection with 30 μg of glyburide, glipizide,...
1055.

Analysis of the Baroreceptor and Vestibular Receptor Inputs in the Rostral Ventrolateral Medulla following Hypotension in Conscious Rats

YanLan, Huan-JunLu, XianJiang, Li-WeiLi, Yan-ZhaoYang, Guang-ShiJin, JooYoungPark, MinSunKim, ByungRimPark, Yuan-ZheJin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.2 11 159-165 (7 pages)

YanLan, Huan-JunLu, XianJiang, Li-WeiLi, Yan-ZhaoYang, Guang-ShiJin, JooYoungPark, MinSunKim, ByungRimPark, Yuan-ZheJin 저
...
- 3,000원
Input signals originating from baroreceptors and vestibular receptors are integrated in the rostral ventrolateral medulla (RVLM) to maintain blood pressure during postural movement. The contribution of baroreceptors and vestibular receptors in the maintenance of blood pressure following hypotension were quantitatively analyzed by measuring phosphorylated extracellular regulated protein kinase (pERK) expression and glutamate release in the RVLM. The expression of pERK and glutamate release in the...
1056.

Long Term Effect of High Glucose and Phosphate Levels on the OPG/RANK/RANKL/TRAIL System in the Progression of Vascular Calcification in rat Aortic Smooth Muscle Cells

YangHoKang, JungSookJin, SeokManSon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.2 5 111-118 (8 pages)

YangHoKang, JungSookJin, SeokManSon 저
...
- 3,000원
Osteoprotegerin (OPG), receptor activator of NF-κB ligand (RANKL)/receptor activator of NF-κB (RANK) axis, and TNF-related apoptosis-inducing ligand (TRAIL) participate in vascular calcification process including atherosclerosis, but their contributions under high glucose (HG) and phosphate (HP) condition for a long-term period (more than 2 weeks) have not been fully determined. In this study, we evaluated the effects of HG and HP levels over 2 or 4 weeks on the progression of vascular...
1057.

Isolation and In Vitro Culture of Vascular Endothelial Cells from Mice

ShinkyuChoi, JiAeeKim, KwanChangKim, SukHyoSuh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.1 6 35-42 (8 pages)

ShinkyuChoi, JiAeeKim, KwanChangKim, SukHyoSuh 저
...
- 3,000원
In cardiovascular disorders, understanding of endothelial cell (EC) function is essential to elucidate the disease mechanism. Although the mouse model has many advantages for in vivo and in vitro research, efficient procedures for the isolation and propagation of primary mouse EC have been problematic. We describe a high yield process for isolation and in vitro culture of primary EC from mouse arteries (aorta, braches of superior mesenteric artery, and cerebral arteries from the circle of...
1058.

Extremely Low Frequency Magnetic Field Modulates the Level of Neurotransmitters

YoonHeeChung, YoungJooLee, HoSungLee, SuJinChung, CheolHeeLim, KeonWoongOh, UyDongSohn, EonSubPark, JiHoonJeong 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.1 3 15-20 (6 pages)

YoonHeeChung, YoungJooLee, HoSungLee, SuJinChung, CheolHeeLim, KeonWoongOh, UyDongSohn, EonSubPark, JiHoonJeong 저
...
- 3,000원
This study was aimed to observe that extremely low frequency magnetic field (ELF-MF) may be relevant to changes of major neurotransmitters in rat brain. After the exposure to ELF-MF (60 Hz, 2.0 mT) for 2 or 5 days, we measured the levels of biogenic amines and their metabolites, amino acid neurotransmitters and nitric oxide (NO) in the cortex, striatum, thalamus, cerebellum and hippo-campus. The exposure of ELF-MF for 2 or 5 days produced significant differences in norepinephrine and vanillyl...
1059.

TRPV1 in Salivary Gland Epithelial Cells Is Not Involved in Salivary Secretion via Transcellular Pathway

SeulkiChoi, Yong-HwanShin, EunNamkoong, Sung-MinHwang, XinCong, GuangyanYu, KyungpyoPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.6 12 525-530 (6 pages)

SeulkiChoi, Yong-HwanShin, EunNamkoong, Sung-MinHwang, XinCong, GuangyanYu, KyungpyoPark 저
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- 3,000원
Transient receptor potential vanilloid subtype 1 (TRPV1) was originally found in sensory neurons. Recently, it has been reported that TRPV1 is expressed in salivary gland epithelial cells (SGEC). However, the physiological role of TRPV1 in salivary secretion remains to be elucidated. We found that TRPV1 is expressed in mouse and human submandibular glands (SMG) and HSG cells, originated from human submandibular gland ducts at both mRNA and protein levels. However, capsaicin (CAP), TRPV1 agonist,...
1060.

Phasic and Tonic Inhibition are Maintained Respectively by CaMKII and PKA in the Rat Visual Cortex

KayoungJoo, ShinHeeYoon, Duck-JooRhie, , Hyun-JongJang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.6 11 517-524 (8 pages)

KayoungJoo, ShinHeeYoon, Duck-JooRhie, , Hyun-JongJang 저
...
- 3,000원
of tonic inhibition relied on protein kinase A activity. Depolarization of membrane potential (5 min of 0 mV holding) potentiated phasic inhibition via Ca2+ and CaMKII but tonic inhibition was not affected. Thus, phasic and tonic inhibition seem to be independently maintained and regulated by different signaling cascades in the same cell. These results suggest that neuromo-dulatory signals might differentially regulate phasic and tonic inhibition in response to changes in brain states.

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