주제분류
- 의약학(123)
- 자연과학(59)
- 농수해양학(56)
- 사회과학(25)
- 특수교육학(22)
- 교육학(8)
- 보건학(6)
- 기타(5)
- 심리학(2)
- 유아교육학(2)
- 공학(1)
- 사회복지학(1)
- 예체능(1)
자료유형
발행기관
- 대한생리학회-대한약리학회(86)
- 대한수의학회(56)
- 한국식물병리학회(48)
- 한국청각언어재활학회(22)
- 인문사회과학기술융합학회(19)
- 대한신경정신의학회(12)
- 한국탄소학회(11)
- 물리치료재활과학회(10)
- 대한생리학회(9)
- 대한약리학회(6)
- 한국교육사회학회(3)
- 한국기초간호학회(2)
- 한국노년학연구회(2)
- 한국데이터정보과학회(2)
- 한국보건기초의학회(2)
- 환태평양유아교육연구학회(2)
- 경인교육대학교 교육연구원(1)
- 국민연금연구원(1)
- 대한신경계작업치료학회(1)
- 아시아장애사회학회(1)
- 은행법학회(1)
- 이화여자대학교 교과교육연구소(1)
- 조선대학교 기초과학연구원(1)
- 한국가족치료학회(1)
- 한국경호경비학회(1)
- 한국교육치료학회(1)
- 한국국제이해교육학회(1)
- 한국성인교육학회(1)
- 한국심리치료학회(1)
- 한국열환경공학회(1)
- 한국인간발달학회(1)
- 한국임상움직임치료학회(1)
- 한국전자파학회(1)
- 한국통계학회(1)
- 한국헬스커뮤니케이션학회(1)
간행물
- THE KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY(86)
- THE PLANT PATHOLOGY JOURNAL (45)
- JOURNAL OF VETERINARY SCIENCE(44)
- AUDIOLOGY AND SPEECH RESEARCH(22)
- 예술인문사회융합멀티미디어논문지(19)
- CARBON LETTERS(11)
- 신경정신의학(11)
- PHYSICAL THERAPY REHABILITATION SCIENCE(10)
- KOREAN JOURNAL OF VETERINARY RESEARCH(구 대한수의학회지)(9)
- 대한생리학회지(9)
- 대한약리학잡지(6)
- 교육사회학연구(3)
- 대한수의학회 학술대회발표집(3)
- 식물병연구(3)
- ASIA-PACIFIC JOURNAL OF RESEARCH IN EARLY CHILDHOOD EDUCATION(2)
- JOURNAL OF KOREAN BIOLOGICAL NURSING SCIENCE(2)
- 한국노년학연구(2)
- 한국데이터정보과학회지(2)
- 한국보건기초의학회지(2)
- ANDRAGOGY TODAY(1)
- JOURNAL OF THE CHOSUN NATURAL SCIENCE(1)
- JOURNAL OF THE KOREAN STATISTICAL SOCIETY(1)
- PSYCHIATRY INVESTIGATION(1)
- 가족과 가족치료(1)
- 교과교육학연구(1)
- 교육논총(1)
- 교육치료연구(1)
- 국민연금연구원 연구보고서(1)
- 국제이해교육연구(1)
- 시큐리티연구(1)
- 아시아장애사회학연구(1)
- 열환경공학(1)
- 은행법연구(1)
- 인간발달연구(1)
- 재활치료과학(1)
- 한국심리치료학회지(1)
- 한국임상움직임치료학회지(1)
- 한국전자파학회논문지(1)
- 헬스커뮤니케이션연구(1)
전체 선택해제
총 311건 검색
본문검색 결과만 보기
-
Cytotoxic Activity and Structure Activity Relationship of Ceramide Analogues in Caki-2 and HL-60 Cells
YongJinKim, EunAeKim, UyDongSohn, ChulBuYim, ChaeukIm 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.6 14 441-447 (7 pages)
a ceramidase inhibitor and induces apoptosis to give potent anticancer activity. A series of thiourea B13 analogues was evaluated for their in vitro cytotoxic activities against human renal cancer Caki-2 and leukemic cancer HL-60 in the MTT assay. Some compounds (12, 15, and 16) showed stronger cytotoxicity than B13 and C6-ceramide against both tumor cell lines, and compound (12) gave the most potent activity with IC50 values of 36 and 9</SUB>ՌM, respectively. Molecular modeling of... -
Regulation of Adenosine-activated GIRK Channels by Gq-coupled Receptors in Mouse Atrial Myocytes
HanaCho 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.3 5 145-150 (6 pages)
or bradykinin prior to a second application of Ado reduced the amplitude of the second IK(Ado) to 25.5±11.6%, 30.5±5.6%, and 96.0±2.7%, respectively. The potency of IK(Ado) inhibition by GqPCRs was different with that observed in acetylcholine-activated GIRK currents (IK(ACh)) (endothelin-1＞phenylephrine＞bradykinin). IK(Ado) was almost completely inhibited by 500ՌM of the PIP2 scavenger neomycin, suggesting low PIP2 affinity of IK(Ado). Taken together, these results suggest that the... -
Intraocular Injection of Muscimol Induces Illusory Motion Reversal in Goldfish
Sang-YoonLee, Chang-SubJung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.6 10 469-473 (5 pages)
of goldfish caused the fish to rotate in the opposite direction to that of the spinning pattern during an optomotor response (OMR) measurement. Muscimol, a GABAA receptor agonist, modified OMR in a concentration- dependent manner. The GABAB receptor agonist baclofen and GABAC receptor agonist CACA did not affect OMR. The observed modifications in OMR included decreased anterograde rotation (0.01∼0.03</SUB>ՌM), coexistence of retrograde rotation and decreased anterograde rotation... -
Arachidonic Acid Activates K＋-Cl?-cotransport in HepG2 Human Hepatoblastoma Cells
YongSooLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.5 11 401-408 (8 pages)
K＋-Cl−-cotransport (KCC) has been reported to have various cellular functions, including proliferation and apoptosis of human cancer cells. However, the signal transduction pathways that control the activity of KCC are currently not well understood. In this study we investigated the possible role of phospholipase A2 (PLA2)-arachidonic acid (AA) signal in the regulatory mechanism of KCC activity. Exogenous application of AA significantly induced K＋ efflux in a dose-dependent manner, which... -
Ser1778 of 53BP1 Plays a Role in DNA Double-strand Break Repairs
Jung-HeeLee, Hyang-MinCheong, Mi-YoungKang, Sang-YoungKim, YoonsungKang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.5 2 343-348 (6 pages)
53BP1 is an important genome stability regulator, which protects cells against double-strand breaks. Following DNA damage, 53BP1 is rapidly recruited to sites of DNA breakage, along with other DNA damage response proteins, including Ճ-H2AX, MDC1, and BRCA1. The recruitment of 53BP1 requires a tandem Tudor fold which associates with methylated histones H3 and H4. It has already been determined that the majority of DNA damage response proteins are phosphorylated by ATM and/or ATR after DNA... -
Heme Oxygenase-1 Induced by Aprotinin Inhibits Vascular Smooth Muscle Cell Proliferation Through Cell Cycle Arrest in Hypertensive Rats
HyoungChulChoi, KwangYounLee, DongHyupLee, YoungJinKang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.4 7 309-313 (5 pages)
Spontaneous hypertensive rats (SHR) are an established model of genetic hypertension. Vascular smooth muscle cells (VSMC) from SHR proliferate faster than those of control rats (Wistar-Kyoto rats; WKY). We tested the hypothesis that induction of heme oxygenase (HO)-1 induced by aprotinin inhibits VSMC proliferation through cell cycle arrest in hypertensive rats. Aprotinin treatment inhibited VSMC proliferation in SHR more than in normotensive rats. These inhibitory effects were associated with... -
Functional Connectivity Map of Retinal Ganglion Cells for Retinal Prosthesis
JangHeeYe, SangBaekRyu, KyungHwanKim, YongSookGoo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.6 4 307-314 (8 pages)
Retinal prostheses are being developed to restore vision for the blind with retinal diseases such as retinitis pigmentosa (RP) or age-related macular degeneration (AMD). Among the many issues for prosthesis development, stimulation encoding strategy is one of the most essential electrophysiological issues. The more we understand the retinal circuitry how it encodes and processes visual information, the greater it could help decide stimulation encoding strategy for retinal prosthesis. Therefore,... -
Lysophosphatidylcholine Increases Ca2+ Current via Activation of Protein Kinase C in Rabbit Portal Vein Smooth Muscle Cells
SeungsooJung, YounghoLee, SungsikHan, YoungwhanKim, TaiksangNam, DucksunAhn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.1 5 31-34 (4 pages)
of the present study was to examine the effects of LPC on L-type Ca2+ current (ICa(L)) activity and to elucidate the mechanism of LPC-induced change of ICa(L) in rabbit portal vein smooth muscle cells using whole cell patch clamp. Extracellular application of LPC increased ICa(L) through whole test potentials, and this effect was readily reversed by washout. Steady state voltage dependency of activation or inactivation properties of ICa(L) was not significantly changed by LPC. Staurosporine (100... -
Neuroprotective Effects of Lithium on NMDA-induced Excitotoxicity in Mouse Cerebrum
Gee-younKwon, Soo-kyungKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.3 1 111-122 (12 pages)
Therefore, it is highly likely that the protection offered by chronic lithium treatment occurred at far upstream of caspase activation, since the chronic lithium treatment increased the expression of Bcl-2, an important antiapoptotic gene known to act upstream of caspase cascade. Timm's histochemistry indicated the complete blockade of the NMDA insults by the treatment. There was no indication of axonal regeneration, which follows synaptic degeneration induced by neuronal damage. Furthermore,... -
Insulin Resistance of Skeletal Muscle was Recovered by Leptin Injection in vivo, but not in vitro, in High-fat Diet Fed Rats
Kyung-OhDoh, Jeong-OakPark, Jeong-RyaeJeon, Jong-YeonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2005, Vol.9 No.2 8 125-130 (6 pages)
the high fat-fed rats, compared to chow diet rats (p＜0.01), and it was decreased significantly by leptin treatment (p＜0.01). The glucose transport was measured under basal and 60μU/ml of insulin with or without 50 ng/ml of leptin. Leptin had no direct stimulatory effect on glucose transport under both basal and insulin-stimulated conditions in vitro. These results demonstrate that leptin injection to high fat diet fed rats recovered impaired insulin responsiveness of the skeletal muscles and...
