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111.

Effects of Chlorhexidine digluconate on Rotational Rate of n-(9-Anthroyloxy)stearic acid in Model Membranes of Total Lipids Extracted from Porphyromonas gingivalis Outer Membranes

Hye-OckJang, Dong-WonKim, Byeong-IllKim, Hong-GuSim, Young-HoLee, Jong-HwaLee, Jung-HaBae, Moon-KyoungBae, Tae-HyukKwon, IlYun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.2 3 83-88 (6 pages)

Hye-OckJang, Dong-WonKim, Byeong-IllKim, Hong-GuSim, Young-HoLee, Jong-HwaLee, Jung-HaBae, Moon-KyoungBae, Tae-HyukKwon, IlYun 저
...
- 3,000원
The purpose of this study was to provide a basis for studying the molecular mechanism of pharmacological action of chlorhexidine digluconate. Large unilamellar vesicles (OPGTL) were prepared with total lipids extracted from cultured Porphyromonas gingivalis outer membranes (OPG). The anthroyloxy probes were located at a graded series of depths inside a membrane, depending on its substitution position (n) in the aliphatic chain. Fluorescence polarization of n-(9-anthroyloxy)stearic acid was used...
112.

Stretch-activated K+ Channels in Rat Atrial Myocytes

JaeBoumYoum 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.6 8 341-318 (8 pages)

JaeBoumYoum 저
...
- 3,000원
Mechanical stimuli to the cardiac myocytes initiate many biochemical and physiological events. Stretch-activated cation channels have been suggested to mediate these events. In this study, cell-attached and inside-out excised-patch clamp methods were used to identify stretch-activated cation channels in adult rat atrial myocytes. Channel openings were increased in cell-attached configuration when negative pressure was applied to the pipette, and also in inside-out excised patches by negative...
113.

Intrinsic Gating in Inward Rectifier Potassium Channels (Kir2.1) with Low Polyamine Affinity Generated by Site Directed Mutagenesis

ISo, , IAshmole, HSoh, CSPark, PJSpencer, MLeyl, PRStanfield, 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.3 3 131-142 (12 pages)

ISo, , IAshmole, HSoh, CSPark, PJSpencer, MLeyl, PRStanfield, 저
...
- 4,100원
We have studied mutant forms of Kir2.1 in which an aspartate residue (D172), important for gating by intracellular polyamines, is replaced by one of three basic residues (Arg, Lys or His). Such channels are highly selective for K+, but show inward rectification that is a shallow function of voltage compared with that found in wild type. This inward rectification occurs with a reduced affinity for spermine and persists in the absence of polyamines. Though the unitary current-voltage relation...
114.

Effects of Chlorhexidine Digluconate on Rotational Rate of n-(9-Anthroyloxy)stearic Acid in Porphyromonas ginginvalis Outer Membranes

Hye-OckJang, Seong-KweonCha, ChangLee, Min-GakChoi, Sung-RyulHuh, Sang-HunShin, In-KyoChung, IlYun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.3 2 125-130 (6 pages)

Hye-OckJang, Seong-KweonCha, ChangLee, Min-GakChoi, Sung-RyulHuh, Sang-HunShin, In-KyoChung, IlYun 저
...
- 3,000원
The aim of this study was to provide a basis for studying the molecular mechanism of pharmacological action of chlorhexidine digluconate. Fluorescence polarization of n-(9-anthroyloxy)stearic acid was used to examine the effect of chlorhexidine digluconate on differential rotational mobility of different positions of the number of membrane bilayer phospholipid carbon atoms. The six membrane components differed with respect to 2, 3, 6, 9, 12, and 16-(9-anthroyloxy)stearic acid (2-AS, 3-AS, 6-AS,...
115.

Relatoinship between Sarcoplasmic Reticular Calcium Release and Na+-Ca2+ Exchange in the Rat Myocardial Contraction

Eun-GiKim, SoonJinKim, ChangMannKo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 14 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.3 4 197-210 (14 pages)

Eun-GiKim, SoonJinKim, ChangMannKo 저
...
- 4,300원
Suppressive role of Na⁢-Ca2⁢ exchange in myocardial tension generation was examined in the negative frequency-force relationship (FFR) of electric field stimulated left atria (LA) from postnatal developing rat heart and in the whole-cell clamped adult rat ventricular myocytes with high concentration of intracellular Ca2⁢ buffer (14 mM EGTA). LA twitch amplitudes, which were suppressed by cyclopiazonic acid in a postnatal age-dependent manner, elicited frequency-dependent and...
116.

Electroencephalographic Correlation Dimension Changes with Depth of Halothane

MaanGeeLee, EunJuPark, JungMeeChoi, MoonHanYoon 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.5 5 491-499 (9 pages)

MaanGeeLee, EunJuPark, JungMeeChoi, MoonHanYoon 저
...
- 3,000원
the last 5-mins of EEG recording at each concentration level. Correlation coefficients between the parameters and the movements were calculated. Standardized values of three parameters, betaL power, median power frequency (MPF), and D2 were derived by calculation based on the number of animals showing the movement in response to a tail clamp. The betaL power had the largest correlation coefficient to spontaneous movement and to the response to a tail clamp than any other band parameter. MPF had...
117.

Electroencephalographic Effects of Chlorpromazine in Rats

JeongEYunMaanGeeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.3 2 245-250 (6 pages)

JeongEYunMaanGeeLee 저
...
- 3,000원
The effects of an antipsychotic, chlorpromazine, on the electroencephalogram (EEG) were observed while rats were awake but immobile. The time course and the dose-dependency of the EEG changes were examined. The method of the power spectrum analysis was used to examine the EEG changes by the drug. The bands were divided into delta (1∼3.5 Hz), theta (3.5∼8 Hz), alpha (8∼13 Hz), beta1 (13∼21 Hz), beta2 (21∼30 Hz) and gamma (30∼50 Hz). In rats, the low dose of chlropromazine (1 mg/kg, i.p.)...
118.

Combination of Electroconvulsive Therapy and Clozapine in Treatment-Resistant Schizophrenia

Jung Hyun Kim, Tak Youn, Jun Gwon Choi, Seong Hoon Jeong, Hee Yeon Jung, Yong Sik Kim, In Won Chung 대한신경정신의학회 Psychiatry Investigation 7 Pages

대한신경정신의학회 Psychiatry Investigation 2018, 제 15권 제 8호 13 829-835 (7 pages)

Jung Hyun Kim, Tak Youn, Jun Gwon Choi, Seong Hoon Jeong, Hee Yeon Jung, Yong Sik Kim, In Won Chung 저
...
- 3,000원
Objective_This study aimed to investigate the effectiveness and tolerability of the combination of electroconvulsive therapy (ECT) in patients with clozapine-treated schizophrenia. Methods_Patients with clozapine-treated schizophrenia during five years of pre-determined period were recruited from Electronic Medical Record. Clinical effects of acute ECT on psychotic symptoms were investigated. We also tried to identify predictive variables requiring maintenance treatment of ECT. Results_Fourteen...
119.

공황장애 환자의 삶의 질

김세주, 김영신, 유상우 대한신경정신의학회 신경정신의학 9 Pages

대한신경정신의학회 신경정신의학 2001, 제 40권 제 3호 4 407-415 (9 pages)

김세주, 김영신, 유상우 저
...
- 3,000원
연구목적： 공황장애는 많은 환자들에게서 잘 회복되지 않는 만성적인 질환으로 알려져 있다. 따라서 공황장애가 환자 들의 삶에 미치는 부정적인 영향은 매우 클 것으로 생각된다. 그러나 공황장애 환자에서 공황발작의 심각도와 빈도, 유병기간, 광장공포증의 정도, 동반된 우울증상의 정도 등 여러 요인들이 삶의 질과 어떤 관련이 있는 지는 잘 알려져 있지 않다. 따라서 본 연구에서는 신체적 건강 영역, 심리적 영역, 사회적 관계 영역, 환경 영역 등을 평가하는 한국판 세계보건기구 삶의 질 척도를 사용하여, 공황장애 환자의...
120.

정신분열병 환자에서 Estrogen Receptor 1 유전형과 Apo E ε4 대립유전자의 상호 작용

최태영, 기백석, 이미경, 박애자, 곽경환, 남범우, 민경준, 박두병 대한신경정신의학회 신경정신의학 16 Pages

대한신경정신의학회 신경정신의학 2002, 제 41권 제 5호 11 831-846 (16 pages)

최태영, 기백석, 이미경, 박애자, 곽경환, 남범우, 민경준, 박두병 저
...
- 4,500원
연구목적： 최근 연구에서 보면 estrogen 수용체 1 유전자(ESR1) 다형성이 알츠하이머형 치매와 연관이 있 다는 연구결과가 있었다. 이에 본 저자는 ESR1 유전형의 정신분열병과의 연합여부와 ApoE ε4 대 립유전자와의 상호작용 여부를 연구하였다. 방 법： 한국인 정신분열병 환자 46명과 정상인 40명을 대상으로 중합효소연쇄반응을 이용해서 ESR1 Xba Ⅰ과 PvuⅡ, 그리고 아포지단백 E(ApoE) 유전자형과 빈도를 비교하고, 환자군에서 임상아형, 가족력 유무, 발병 연령에 따라 차이가 있는지를 비교 분석하였다. 결 과： 정신분열병...

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