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121.

The Modulatory Role of Spinally Located Histamine Receptors in the Regulation of the Blood Glucose Level in D-Glucose-Fed Mice

Yun-BeomSim, Soo-HyunPark, Sung-SuKim, Chea-HaKim, Su-JinKim, Su-MinLim, Jun-SubJung, Ohk-HyunRyu, Moon-GiChoi, Hong-WonSuh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.1 5 41-46 (6 pages)

Yun-BeomSim, Soo-HyunPark, Sung-SuKim, Chea-HaKim, Su-JinKim, Su-MinLim, Jun-SubJung, Ohk-HyunRyu, Moon-GiChoi, Hong-WonSuh 저
...
- 3,000원
The possible roles of spinal histamine receptors in the regulation of the blood glucose level were studied in ICR mice. Mice were intrathecally (i.t.) treated with histamine 1 (H1) receptor agonist (2-pyridylethylamine) or antagonist (cetirizine), histamine 2 (H2) receptor agonist (dimaprit) or antagonist (ranitidine), histamine 3 (H3) receptor agonist (α-methylhistamine) or antagonist (car-cinine) and histamine 4 (H4) receptor agonist (VUF 8430) or antagonist (JNJ 7777120), and the blood...
122.

Anti-Inflammatory and Anti-Superbacterial Properties of Sulforaphane from Shepherd’s Purs

WooJinChoi, SeongKeunKim, HeeKukPark, UyDongSohn, WonyongKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.1 4 33-39 (7 pages)

WooJinChoi, SeongKeunKim, HeeKukPark, UyDongSohn, WonyongKim 저
...
- 3,000원
Shepherd’s purse, Capsella bursa-pastoris (L.) Medik., has been considered a health food for centuries in Asia and is known to contain the isothiocyanate compound sulforaphane. In this study, we evaluated the anti-inflammatory and antibacterial properties of a sulforaphane-containing solution (SCS) isolated from shepherd’s purse. SCS had significant anti-inflammatory activity indicated by the decreased levels of nitric oxide (NO), cytokines (interleukin 1β [IL-1β], IL-6, and IL-10), and...
123.

Antiapoptotic Effect of Paricalcitol in Gentamicin-induced Kidney Injury

SangHeonSuh, KoEunLee, JeongWooPark, InJinKim, OkKim, ChangSeongKim, JoonSeokChoi, EunHuiBae, SeongKwonMa, JongUnLee, SooWanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.5 9 435-440 (6 pages)

SangHeonSuh, KoEunLee, JeongWooPark, InJinKim, OkKim, ChangSeongKim, JoonSeokChoi, EunHuiBae, SeongKwonMa, JongUnLee, SooWanKim 저
...
- 3,000원
While the anti-apoptotic effect of paricalcitol has been demonstrated in various animal models, it is not yet clear whether paricalcitol attenuates the apoptosis in gentamicin (GM)-induced kidney injury. We investigated the effect of paricalcitol on apoptotic pathways in rat kidneys damaged by GM. Rats were randomly divided into three groups: 1) Control group (n=8), where only vehicle was delivered, 2) GM group (n=10), where rats were treated with GM (150 mg/kg/day) for 7 days, 3) PARI group...
124.

Ineffective Doses of Dexmedetomidine Potentiates the Antinoci-ception Induced by Morphine and Fentanyl in Acute Pain Model

MuminUnal, SinanGursoy, AhmetAltun, CevdetDuger, IclalOzdemirKol, KenanKaygusuz, IhsanBagcivan, CanerMimaroglu 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.5 6 417-422 (6 pages)

MuminUnal, SinanGursoy, AhmetAltun, CevdetDuger, IclalOzdemirKol, KenanKaygusuz, IhsanBagcivan, CanerMimaroglu 저
...
- 3,000원
The aim of this study was to evaluate the synergistic potentiation effect of ineffective doses of dexmedetomidine on antinociception induced by morphine and fentanyl in acute pain model in rats. Seventy albino Wistar rats were separated into 7 groups. Data for the control and sham groups were recorded. The ineffective dose of dexmedetomidine was investigated and found to be 3 Ռg/kg. Each group was administered the following medications: 3 mg/kg morphine (intraperitoneal) to Group 3, 5...
125.

Chronic Administration of Baicalein Decreases Depression-Like Behavior Induced by Repeated Restraint Stress in Rats

BombiLee, BongjunSur, JinheePark, Sung-HunKim, SunohKwon, MijungYeom, InsopShim, HyejungLee, Dae-hyunHahm 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.5 3 393-403 (11 pages)

BombiLee, BongjunSur, JinheePark, Sung-HunKim, SunohKwon, MijungYeom, InsopShim, HyejungLee, Dae-hyunHahm 저
...
- 4,000원
Baicalein (BA), a plant-derived active flavonoid present in the root of Scutellaria baicalensis, has been widely used for the treatment of stress-related neuropsychiatric disorders including depression. Previous studies have demonstrated that repeated restraint stress disrupts the activity of the hypothalamic-pituitary-adrenal (HPA) axis, resulting in depression. The behavioral and neurochemical basis of the BA effect on depression remain unclear. The present study used the forced swimming test...
126.

Mechanism of Relaxation Via TASK-2 Channels in Uterine Circular Muscle of Mouse

SeungHwaHong, RohyunSung, YoungChulKim, HikaruSuzuki, WoongChoi, YeonJinPark, IllWoonJi, ChanHyungKim, SunChulMyung6, MooYeolLee, TongMook 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.4 14 359-365 (7 pages)

SeungHwaHong, RohyunSung, YoungChulKim, HikaruSuzuki, WoongChoi, YeonJinPark, IllWoonJi, ChanHyungKim, SunChulMyung6, MooYeolLee, TongMook 저
...
- 3,000원
Plasma pH can be altered during pregnancy and at labor. Membrane excitability of smooth muscle including uterine muscle is suppressed by the activation of K＋ channels. Because contractility of uterine muscle is regulated by extracellular pH and humoral factors, K＋ conductance could be connected to factors regulating uterine contractility during pregnancy. Here, we showed that TASK-2 inhibitors such as quinidine, lidocaine, and extracellular acidosis produced contraction in uterine circular...
127.

Changes in c-Fos Expression in the Forced Swimming Test: Common and Distinct Modulation in Rat Brain by Desipramine and Citalopram

SunHyeChoi, SungChung, JinHeeCho, YunHaCho, JinWookKim, JeongMinKim, HeeJeongKim, HyunJuKim, KyungHoShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.4 10 321-329 (9 pages)

SunHyeChoi, SungChung, JinHeeCho, YunHaCho, JinWookKim, JeongMinKim, HeeJeongKim, HyunJuKim, KyungHoShin 저
...
- 3,000원
Rodents exposed to a 15-min pretest swim in the forced swimming test (FST) exhibit prolonged immobility in a subsequent 5-min test swim, and antidepressant treatment before the test swim reduces immobility. At present, neuronal circuits recruited by antidepressant before the test swim remain unclear, and also less is known about whether antidepressants with different mechanisms of action could influence neural circuits differentially. To reveal the neural circuits associated with antidepressant...
128.

Curcumin Attenuates Radiation-Induced Inflammation and Fibrosis in Rat Lungs

YuJiCho, ChinOkYi, ByeongTakJeon, YiYeongJeong, GiMunKang, JungEunLee, GuSeobRoh, JongDeogLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.4 3 267-274 (8 pages)

YuJiCho, ChinOkYi, ByeongTakJeon, YiYeongJeong, GiMunKang, JungEunLee, GuSeobRoh, JongDeogLee 저
...
- 3,000원
A beneficial radioprotective agent has been used to treat the radiation-induced lung injury. This study was performed to investigate whether curcumin, which is known to have anti-inflammatory and antioxidant properties, could ameliorate radiation-induced pulmonary inflammation and fibrosis in irradiated lungs. Rats were given daily doses of intragastric curcumin (200 mg/kg) prior to a single irradiation and for 8 weeks after radiation. Histopathologic findings demonstrated that macrophage...
129.

Effect of Cholera Toxin Administered Supraspinally or Spinally on the Blood Glucose Level in Pain and D-Glucose Fed Animal Models

Yun-BeomSim, Soo-HyunPark, Yu-JungKang, Sung-SuKim, Chea-HaKim, Su-JinKim, Jun-SubJung, Ohk-HyunRyu, Moon-GiChoi, Seong-SooChoi, Hong-WonS 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.2 8 163-167 (5 pages)

Yun-BeomSim, Soo-HyunPark, Yu-JungKang, Sung-SuKim, Chea-HaKim, Su-JinKim, Jun-SubJung, Ohk-HyunRyu, Moon-GiChoi, Seong-SooChoi, Hong-WonS 저
...
- 1,500원
In the present study, the effect of intrathecal (i.t.) or intracerebroventricular (i.c.v.) administration with cholera toxin (CTX) on the blood glucose level was examined in ICR mice. The i.t. treatment with CTX alone for 24 h dose-dependently increased the blood glucose level. However, i.c.v. treatment with CTX for 24 h did not affect the blood glucose level. When mice were orally fed with D-glucose (2 g/kg), the blood glucose level reached to a maximum level at 30 min and almost returned to...
130.

Differential Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on Motor Behavior and Dopamine Levels at Brain Regions in Three Different Mouse Strains

Keun-SungLee, Jin-KooLee, Hyung-GunKim, HakRimKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.1 13 89-97 (9 pages)

Keun-SungLee, Jin-KooLee, Hyung-GunKim, HakRimKim 저
...
- 3,000원
Developing an animal model for a specific disease is very important in the understanding of the underlying mechanism of the disease and allows testing of newly developed new drugs before human application. However, which of the plethora of experimental animal species to use in model development can be perplexing. Administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is a very well known method to induce the symptoms of Parkinson's disease in mice. But, there is very limited...

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