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Effect of UV Irradiation and Rebamipide on the Blood Flow and Viability of Rabbit Skin Flap
Eung-JooSuh, Hyoung-ChulChoi, Uy-DongSohn, Jeoung-HeeHa, Kwang-YounLee, Won-JoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.5 14 581-589 (9 pages)
This study was undertaken to examine the effects of ultraviolet light (UVL) and rebamipide on the cutaneous blood flow and tissue survival on rabbit skin flap. In a random bipedicle flap, Laser Doppler Flowmetry (LDF) was employed to measure the blood flow of flap (BFF). Wound Margin Strength (WMS) measured by force transducer and Light microscophy were used for evaluation of tissue viability. Single exposure to UVL increased the BFF gradually for more than 15 hours, and decreased the... -
Role of Intracellular Taurine in Monensin-induced Na+, Ca++ Accumulation and Mechanical Dysfunction in Isolated Rat Hearts
Young-hoonKim, Jong-wanPark, Myung-sukKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.5 9 537-546 (10 pages)
dose-dependent increase in intracellular Na accompanied with a subsequent increase in intracellular Ca and a mechanical dysfunction. In this monensin-treated heart, myocardial taurine content was decreased with a concomittent increase in the release of taurine. The monensin-induced increases in intracellular Na, Ca and depression of cardiac function were prevented in the hearts of which taurine content had been increased by high-taurine diet. Conversely,... -
Altered Vascular Calcium Regulation in Hypertension
Won-jaeKim, Jong-unLee, YongHyunPark, SangChaeNam 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.5 8 529-535 (7 pages)
The present study was aimed at investigating whether the vascular calcium regulation is altered in hypertension. Two-kidney, one clip (2K1C) and deoxycorticosterone acetate (DOCA)-salt hypertension were made in rats, and their thoracic aortae were taken 4 weeks later. The isometric contractile response and calcium uptake of the endothelium-denuded aortic preparations were determined. Caffeine (0.1∼35 mmol/L) induced a greater contraction in 2K1C and DOCA-salt hypertension than in normotensive... -
Effect of t-butylhydroperoxide on Na+-dependent Glutamate Uptake in Rabbit Brain Synaptosome
HyunJeLeeYongKeunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.4 3 367-376 (10 pages)
(dibucaine, butacaine and quinacrine). However, the effect was prevented by iron chelators (deferoxamine and phenanthroline) and phenolic antioxidants (N,N'-diphenyl-phenylenediamine, butylated hydroxyanisole, and butylated hydroxytoluene). At low concentrations (<1.0 mM), t-BHP inhibited glutamate uptake without altering lipid peroxidation. Moreover, a large increase in lipid peroxidation by ascorbate/Fe2+ was not accompanied by an inhibition of glutamate uptake. The impairment of glutamate... -
Reduction of TNFα-induced Oxidative DNA Damage Product, 8-Hydroxy-2′-Deoxyguanosine, in L929 Cells Stably Transfected with Small Heat Shock Protein
Young-MeePark, Eun-MiChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 11 209-219 (11 pages)
the level of 8-hydroxy-2′-deoxyguanosine (8 ohdG), which has been increasingly recognized as one of the most sensitive markers of oxidative DNA damage. Our results clearly demonstrated that the level of 8 ohdG increased in L929 cells in a TNFα dose-dependent manner. Subsequently, we asked whether small HSP has a protective effect on TNFα-induced oxidative DNA damage. To accomplish this goal, we have stably transfected L929 cells with mouse small hsp cDNA (hsp25) since these cells are devoid... -
Two Types of Voltage-dependent Outward Potassium Currents in Smooth Muscle Cells of Rabbit Basilar Atery
TongMookKang, InsukSo, DaeYongUhm, KiWhanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 15 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 7 169-183 (15 pages)
and inactivation of IK(V) was at the more hyperpolarized range than that of Ito contrary to the reports in other vascular SMCs. Tetraethylammonium chloride (TEA; 10 mM) markedly inhibited IK(V) but little affected Ito. 4-Aminopyridine (4-AP) had similar inhibitory potency on both currents. While a low concentration of Cd2+ (0.5 mM) shifted the current- voltage relationship of Ito to the positive direction without change of maximum conductance, Cd2+ did not cause any appreciable change for IK(V). -
The Influence of N6-cyclopentyladenosine and Magnesium on Norepinephrine Release in the Rat Hippocampus
YeungBongPark, SangDukPark, BongKyuChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 3 135-142 (8 pages)
(3 Hz, 5 V cm-1, 2 ms, rectangular pulses), and the influence of various agents on the evoked tritium outflow was investigated. N6-cyclopentyladenosine (CPA), in concentrations ranging from 0.1 to 10 ㄍM, decreased the [3H]-NE release in a dose-dependent manner without changing the basal rate of release, and these effects were significantly inhibited by 8-cyclopentyl-1,3-dipropylxanthine (DPCPX, 2 ㄍM) treatment. When the magnesium concentration was reduced to 0.4 mM or completely... -
Predicting Working Memory Capacity in Older Subjects Using Quantitative Electroencephalography
Jae Hyuk Shin, Kyungun Jhung, Jae Seok Heo, Suk Kyoon An, Jin Young Park 대한신경정신의학회 Psychiatry Investigation 6 Pages
대한신경정신의학회 Psychiatry Investigation 2018, 제 15권 제 8호 7 790-795 (6 pages)
brain network parameters were, calculated. In the feature extraction stage, the statistical power of the spectral and network parameters was calculated for the low-, moderate-, and high-performance groups. Afterward, the highly-powered features were selected as input into a support vector machine classifier with two discrete outputs: low- or high-performance groups. The classifier was then trained using a training set and the performance of the classification process was evaluated using a test... -
요통을 호소하는 신병들의 정신의학적 특성
이종훈, 조주연 대한신경정신의학회 신경정신의학 8 Pages
대한신경정신의학회 신경정신의학 1998, 제 37권 제 1호 6 75-82 (8 pages)
저자는 요통을 호소하는 입대한 장병들의 정신의학적 특성을 알아보기 위해 본 연구를 시도하였다. 환자군 은 1996년 9월 6일부터 11월 15일사이에 ○○사단 신병교육대에 입대한 48명이고, 대조군은 이들과 같은 시 기에 입대한 장병중에서 통증을 호소하지 않는 장병 48명을 무작위 추출하였다. 각 군은 MMPI, Beck의 우 울척도, Zung의 자가통증척도, 그리고 Barron의 자아강도척도를 실시했다. 자료는 chi-square test 또는 ttest에 의해 분석되었다. 검사의 결과는 다음과 같다. 1) 인구학적 변인상 환자군이 경제적으로 낮은 계층에... -
공황장애 약물치료의 최근 경향
대한신경정신의학회 신경정신의학 1998, 제 37권 제 4호 3 620-631 (12 pages)
현재 공황장애의 치료는 크게 약물치료와 인지행동치료로 구분되며, 두가지 치료를 함께 병행했을 때 가장 효과가 좋은 것으로 인정되고 있다. 1960년대에 imipramine의 독특한 항공황효과가 알려진 이후, 항우울제 는 공황장애의 1차치료약물로 사용되었다. 그러나 최근의 임상연구결과 항우울제인 SSRIs가 공황발작의 빈 도와 강도를 현저히 감소시키고, 항공황효과면에서 고전적항우울제에 필적할만하다. 또한 SSRIs가 다른 삼 환계항우울제, 단가아민 산화효소억제제, 벤조다이아제핀에 비해 전체적으로 안전성, 부작용, 의존성의...


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